2E7V,1IVZ


Conserved Protein Domain Family
SEA

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pfam01390: SEA 
SEA domain
Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.
Statistics
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PSSM-Id: 460188
Aligned: 184 rows
Threshold Bit Score: 41.4543
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2E7V_A          5 YFYHSSFQI-----LN-VEYTEALNSPATHEYRTLSERIEAMITDEFRGss-lKSEFIRTHV------VKL---RKe--g 66  
XP_003117737  117 QSYSGSFTI-----LR--QASEMFDMKNTNNYYLTFNRIQDGLDNIFVTssllRPYAAQAIL------TDL--------- 174 
EGT43132       74 QSYSGSFTI-----PQ--QASEIFDTKNTNTYFSIFNLIQNALDQIFVTss-lRPYAAQAIL------TDL--------- 130 
OCA39017       47 KLYSCSLNI-----VS-HELTYDLTRPESSSFRTEAAHLQKLVNGLVLAse-lAAYHNSCTV------YAF---GE---- 106 
CAG12530       45 QQYVVYLSI-----LN-RNFSADLSSHTSPTFKREARGVQSTVEKVMRSss-lSRYFNYTTV------FAF---GE---- 104 
XP_011220039  324 KLFPGSIIV-----K--VSEASGLGDENSLVYQKLHIEITDFFKNTFDNsd-yGQTVIEEVStspsarSEM---RAg--d 390 
Q9H3R2        214 KVFPGKISV-----TVsETFDPE--EKHSMAYQDLHSEITSLFKDVFGT-----SVYGQTVIltvstsLSP---RSemra 278  human
CAF90245      133 LYHNGTFRL-----PN-QDFTKDLINMSSTQSQVLAASLQEKIAGFYTSspalGRYFSEASI------SAFrdgENdq-s 199 
POM38282     3008 ESWNVPLWVvrdkeKP-IIFSESFDNPQTPVYKDYSKRLEKGIEGCYPHte-lRNAFVTAEVndivnpVLM---NAsy-d 3081 Caenorhabditi...
XP_016848065  255 VEFSILLPE--------EKYTDELSDPFTEEYQQLSLQFVSEIQNAYEG----LPGYKNIHV------NEF---RPsq-d 312  green anole
2E7V_A         67 TGVVADVVMKFRSS-KRNNRKVMKTRIQSVLRRL--SSS 102 
XP_003117737  175 QNRGNDLAVLFRVN-MLGGGSIDQNTVAAVVRDNinQLQ 212 
EGT43132      131 QNRGNDLTVLFRVN-MFGGGNVDQNTIAGIIRSNlnQLQ 168 
OCA39017      107 GSLKIYFWVSLEVP-NTDLKYVTESSVTAALNSVlhKKT 144 
CAG12530      105 GSVVAHLWLVMSVP-SSHVGAITVEKLSKSLQKGleRYS 142 
XP_011220039  391 NGVVVEVLNIFIET-TKENENTVSETIRKAIENStaGIT 428 
Q9H3R2        279 DDKFVNVTIVTILA---ETTSDNEKTVTEKINKAirSSS 314  human
CAF90245      200 PSVIAHYRLKFLMP---EEEEDQLRNFTLSREMVfnVFR 235 
POM38282     3082 TGLLFNTTVHFRKGmVQVPSDAYYQLVKYITKENnnEVG 3120 Caenorhabditis remanei
XP_016848065  313 D---SGMEVLYTVV---FDGEAISNATWDLINLQsnKVE 345  green anole
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