Conserved Protein Domain Family
COG5391

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COG5391: COG5391 
Phox homology (PX) domain protein [Intracellular trafficking and secretion / General function prediction only]
Statistics
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PSSM-Id: 227680
Aligned: 13 rows
Threshold Bit Score: 338.31
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
19115109 145 NSPPASTTALNLSSNIVPSINESKILEQEDDDVSNKSLPHAQQSIIRSFPDIQKQPKGFFSYPSSTVSSIAPSTLEAGNL 224 fission yeast
19173623     --------------------------------------------------------------------------------     Encephalitozoon cun...
19114817     --------------------------------------------------------------------------------     fission yeast
19113529   7 NNPFSGSDNRSASSAVNVEPKVEPSQHQGSSSVKENAISQPNESFQSRNMFFQKDVDSVVDSALDPNGIVITGAMKAESG 86  fission yeast
19112676     --------------------------------------------------------------------------------     fission yeast
19113272     --------------------------------------------------------------------------------     fission yeast
19075495   1 MAQDDSYEEKPEVISSDSGGSGYSTEIQIVGTVTSSDGSYVEYEIVHQKRSVWRRYSDFESLVKLMRRQYPAAIVPPIPG 80  fission yeast
19075429  59 KRSVNLKSLPFETLTLDSAPLGPLQFSDAPSMAPENNRLEVGLNTKINPLKGSSPALNADFSANKPWISEVNSFSPSPIG 138 fission yeast
6320090    7 VQENAKLNSETRNTGKAEPPHGTTEYVAEAEISKNGVGSPKKSPKKGKVGKGDNNKVETELVHTALLEKDNPFMEEGPTG 86  baker's yeast
6320633   57 SSSSLPSSPAHSSSAGSSRASTSSSTSSHAVVEADAETEPFVSLSMSTTATISKFTPHDMNGTQQIQIIDAGDFKDPWGK 136 baker's yeast
1352971      --------------------------------------------------------------------------------     baker's yeast
1709190    1 MDNYEGSDPWNTSSNAWTKDDDHVVSTTNSEPSLNGISGEFNTLNFSTPLDTNEEDTGFLPTNDVLEESIWDDSRNPLGA 80  baker's yeast
10720283     --------------------------------------------------------------------------------     baker's yeast
19115109 225 HSQQPPKFSVDSSVDDNAITPRKPFSKIPNRLSPSTQPLLSNSRHSSFRLASSSTSFPASLEMN----VDIDLEPSGYFF 300 fission yeast
19173623   1 ----------------------------------------------MEEKSVLEITIPGSRNVQ--------NKYTEYEV 26  Encephalitozoon cun...
19114817   1 ---------------------------------MSDSVNLDEPSTNSTHFLQCLVTEPRKELQG------SRDTHVSYLI 41  fission yeast
19113529  87 SHIVYIIKLQDSEIHHRYSEFASLRVQLSRLYPTCLVPPLPDKHKIMDYLINVTKNQRMSRMLE------ERKRLLQLFL 160 fission yeast
19112676   1 -------------------------------------------------MLKCTIKNEQIETLR------SGDTFVSYEI 25  fission yeast
19113272   1 --------------------------MDKLSRPEIRQQTTQQMYDVPENILEIDVINPQTHGIG-------RNMFTTYEI 47  fission yeast
19075495  81 KQSLLSYAKHPRKAKSDAEFLNFRSRMLELFLRQCLLHPCIRSNPIFDKFIHSTVSWHVTLSSLdl-pKDSNTDPLRLPP 159 fission yeast
19075429 139 ATENPTIPNSEQTVDTLDAASSSAPNFTHTVSSASSQKQGSTSLTDTENQKAHPAAAPQSLTPFy---IQVHDPHTVKEI 215 fission yeast
6320090   87 FTKSALLEIPGMRSHNLKNPNEDYEDDSEGLLPLNQESNAETCRTSLSGSINSMNGETSASEEPs---VSNRKKSARIHI 163 baker's yeast
6320633  137 HAIGYVILYENNKIIRRYSEFHSLRQSLTRLLPTIIIPPIPSKHSLLKYIWSPINAANDSKIIStrkkMLNSFLSNCLNI 216 baker's yeast
1352971    1 -----------------------MTDKGKNDLTSKAKDKARGNPEKPPYWFEIIVSDPQKRTGD----PGSSSGYVSYQI 53  baker's yeast
1709190   81 TGMSQTPNIAANETVIDKNDARDQNIEESEADLLDWTNNVRKTYRPLDADIIIIEEIPEREGLL--------FKHANYLV 152 baker's yeast
10720283   1 ---------------MPREFKSFGSTEKSLLSKGHGEPSYSEIYAEPENFLEIEVHNPKTHIPNg---MDSKGMFTDYEI 62  baker's yeast
19115109 301 YRHNNYIISDSSNTR---------EVLRRYSDFFWLHSYLMKKYpfr-rvPLIPLKKFHSKCFNSKQFFrtpp------- 363 fission yeast
19173623  27 VCVTNSRSFRKCYT----------KVFRRYSDFHRLHCRLKYLM--------KVLPEFPRKRWN---------------- 72  Encephalitozoon cun...
19114817  42 ITKTNLSIFTRAEC----------KVRRRFSDFVKLQEILSRMN------EDCVVPPLPAKHKLEYIKG----------- 94  fission yeast
19113529 161 RRVAQHPILGLSEVFr-------kFLSRHVSWKEVLHSPPISCLpk---dLLKAPPADPSSKENAELYKelpips----- 225 fission yeast
19112676  26 ETESDLPVFEDKKF----------SVRRRYKDFEMLHNILSHDY------NGYAIPPLPRKYTVSSFSG----------- 78  fission yeast
19113272  48 VCRTNMPYFRLHNS----------SVRRRYSEFEKFHDMLERES------GRVSIPPLPGKIFT---------------- 95  fission yeast
19075495 160 IATEHDPFAHLRSSMp-------lVMANSLSPPSSRALKPIHSLs----nPSTASSLEPSSPLGSE-------------- 214 fission yeast
19075429 216 TKSHTVYSVSTRLEEhnqpsvsnvTVQRRYNDFAFLYQLLSNNH------PGCIIPPIPEKQVVG--------------- 274 fission yeast
6320090  164 LEAKRVSEGQGRAYIayviqfensTVQRRYSDFESLRSILIRLF------PMTLIPPIPEKQSIKNYGKsitgssskyll 237 baker's yeast
6320633  217 QEISNDIVFQKFLNPefn---wkdVLSSSPIIILPLNNLLAPPLsptkpsPLHSILPIPSNSSLRNYNSiwqq------- 286 baker's yeast
1352971   54 STKTNNTSFYDNRGDpes----iiVVHRRYSDLLLLHDILLNRF------PTCIIPPLPDKKVFQYIAG----------- 112 baker's yeast
1709190  153 KHLIALPSTSPSEER---------TVVRRYSDFLWLREILLKRY------PFRMIPELPPKRIGS--------------- 202 baker's yeast
10720283  63 ICRTNLPSFHKRVS----------KVRRRYSDFEFFRKCLIKEIsml-nhPKVMVPHLPGKILLS--------------- 116 baker's yeast
19115109 364 ----------------pglSDFVNDLSHHPIFSNDEVVRVFFTEPNVFK------------NWRRENQKRIDQEIEQFLV 415 fission yeast
19173623  73 --------------------KMSREVVEERVRMLTVYMRFVCDQLLRSR------------EGVEKIEADIVAFIQGRSS 120 Encephalitozoon cun...
19114817  95 -------------------GRFSDNFINRRAKLLNRYITRCALHPVLHQsphfi--aflenPNWNNYVRFFIQPKLNNTS 153 fission yeast
19113529 226 --------------ktlvpRDNYDDVGKNFLMLEDTLQQYSIVAQEESNlfnqi--vlsnsKYCLAHSTLGAMFNALSLS 289 fission yeast
19112676  79 -------------------GSLSPIFIARRMQSLQTFLDRCSTHPVISNsmhmy--qflenNSWKSYYHNAWMQSENTKS 137 fission yeast
19113272  96 -------------------QRFRDDVIEERRQGLENFLRLVAGHPL-----------------IQTHSRVLSSFLQSPEF 139 fission yeast
19075495 215 -------------------DECHPPTSDMQPTHELNESPSTPTAPDFPHyn---------sSPSELSPTQRRSSISNGKD 266 fission yeast
19075429 275 --------------------RFDDEFIEQRRAALEVMLRKISAHPVLR-------------DDYSFKLFLEAETFDPRMT 321 fission yeast
6320090  238 psegsgsvdlslsvihasvNNSDEKLIRHRIRMLTEFLNKLLTNEEITKtsiitdfldpnnHNWHEFVNSSSTFSSLPKS 317 baker's yeast
6320633  287 ----------------hitVKSHNEISNLPTEILQNESQFTHIENLFQNykriithllkniRSNKSHFHSLSTYFAELGA 350 baker's yeast
1352971  113 -------------------DRFSQRFTQKRCHSLQNFLRRVSLHPDLSQskvfk--tflvsKDWESHRKVLQDSLQPNKD 171 baker's yeast
1709190  203 -------------------QNADQLFLKKRRIGLSRFINLVMKHPKLSNdd--------lvLTFLTVRTDLTSWRKQATY 255 baker's yeast
10720283 117 -------------------NRFSNEVIEERRQGLNTWMQSVAGHPL-----------------LQSGSKVLVRFIEAEKF 160 baker's yeast
19115109 416 VPQSQVPDASETVKER------------------------------------------------LLKLNMSTTTAINNQL 447 fission yeast
19173623 121 VPET---------------------------------------------------------------------------- 124 Encephalitozoon cun...
19114817 154 KLDEISDSLLNAFSKLke---------------------------------------------ePTEFDIQRDHVQQFMF 188 fission yeast
19113529 290 ESGKLLTALEKVGQANdhtclasid-------------------------------fmhnfviaVIEPLQELSKDAKNMR 338 fission yeast
19112676 138 KGNNVSGGIESSIQNLdp---------------------------------------------yAQSLYETAKQLLQNAD 172 fission yeast
19113272 140 KPTP---------------------------------------------------------------------------- 143 fission yeast
19075495 267 APSPVLKDLTSYTQEViv---------------------------------------------cRKFLHHSLSPSIHSTL 301 fission yeast
19075429 322 HRTTLIESSSSPLRSGps---------------------------------------------tSGLLDSFTSAFHTSGS 356 fission yeast
6320090  318 ILQCNPLDPTNTTRIHamlpipgsssqlllnkesndkkmdkersksftnieqdykqyenlldngIYKYNRRTTKTYHDLK 397 baker's yeast
6320633  351 YYNAFSLENDITMPNSlr--------------------------------------------esENNSNNPMMEIISHIE 386 baker's yeast
1352971  172 EVTDAFMNAFKTVHKQne---------------------------------------------eFTEIREKSDKLDRTVT 206 baker's yeast
1709190  256 DTSNEFADKKISQEFMkm---------------------------------------------wKKEFAEQWNQAASCID 290 baker's yeast
10720283 161 VG------------------------------------------------------------------------------ 162 baker's yeast
19115109 448 NIFRIFEKMIFTLQHFHEDFLRLQNSFNCLLDSGL-------YHQVFTSTFAQNESKIMSMAS---GHFYNIDSLLHQQN 517 fission yeast
19173623     --------------------------------------------------------------------------------     Encephalitozoon cun...
19114817 189 GISNLEGSIQKLLRLEKALESDYEDVSIQFDRLAS-------LDQALDVPIESIQNALQQTG-----TEYANLTEKLTLL 256 fission yeast
19113529 339 HIFIFRKMKFIQQVMVEELLTRKKSFLHLLERRERhaarlqqAIGEVDGDVILNRESEATLGVnnaQTSRSTIPEEDPLF 418 fission yeast
19112676 173 TDLSKLEKTCVQYMNSVQNFPTDIPVPSNLSISNLd------VVSVEFKRLKRNSIFLINSFHskvITSIQDLEDYMVVF 246 fission yeast
19113272     --------------------------------------------------------------------------------     fission yeast
19075495 302 SSISKMESCLSKLGSAFHSLTALNEIQLANHLQVIana--feFSGMYAKEFEQEFNSSVYEKMvqsMQLAKCAADALKYK 379 fission yeast
19075429 357 SKFSEQDPILIEAKDTLDSLETQLKSVYHALLLSId------QRIQFASAIHDFGEAVGNLSLvdlEPTLSSKFDGLSQL 430 fission yeast
6320090  398 SDYNEIGEVFAQFAHEQAQVGELAEQLSYLSNAFSgs---siSLEKLVGRLYYNINEPLNESVhmaTSARELIKYRKLKY 474 baker's yeast
6320633  387 KTGHSFDVIYISSEILIEKYTSILEDPINELLQFLne----sFKVLNFKKLKFLQFKILERLIiekETKLSSLTEIENQL 462 baker's yeast
1352971  207 KIDKLFHKVVKKNDSMSEDYTKLGSNLQELQELVT-------GENEELAAKLKIFNEGVTQLS---YGLQDLTKYLDYEY 276 baker's yeast
1709190  291 TSMELWYRITLLLERHEKRIMQMVHERNFFETLVDn------FSEVTPKLYPVQQNDTILDIN---NNLSIIKKHLETTS 361 baker's yeast
10720283     --------------------------------------------------------------------------------     baker's yeast
19115109 518 DAVKHTFL--LGLSKEIKILISLRLLIERISEVFSTDLTKVRHTISNDENLLRETANSDESGRNRTFL------------ 583 fission yeast
19173623     --------------------------------------------------------------------------------     Encephalitozoon cun...
19114817 257 LDTIKDVE--SYAHSLKELLKRRDQKQQDVEALQEYSAKLSLERDKISSGGSNGFSLSKTLDDLRGID------------ 322 fission yeast
19113529 419 NDEESKEPsvPLMGTDQPLENYHDGNGEQTEECLRDLRHNQSQDFETVSQDTSLTSVTVLPRTIRDVFdrirfvl-nglt 497 fission yeast
19112676 247 KSLIKSRE--QKVKQFEHFQQIVQSNSNNPDQSSRSDPNFVEATPVVQQTPELKPSPNTTIRTSSLFS------------ 312 fission yeast
19113272     --------------------------------------------------------------------------------     fission yeast
19075495 380 QLKIQQRDflQDQLIHSNTMSATDSMVAASPTIHPATRLNTIQRAVVSQAKKGYTIFGRLQNVLHDFV------------ 447 fission yeast
19075429 431 QVELRFVQ--ERKVAQDNLTLGTTLEEYIRYVESAKNAFTTRQKLWQTWQSSVQAVSRAKTQLEKCKK------------ 496 fission yeast
6320090  475 LQNEMIKK--SLNSKRAQLEKLEAQNNEYKDVDKIIDNEMSKSHTINLERPNNNTGSGGKSYGGKLFNgfnklasmvkds 552 baker's yeast
6320633  463 QKINESLTr-STILTDENYKDTKAADLTFVKKDVRSLSKSSSNSSSSGHQNEIHIGASKLNYKTSTPTmnlnkl----ei 537 baker's yeast
1352971  277 IVDLKDLE--HYIDSMRQLIKLKDQKQIDYEELSDYLTRSIKEKNNLISGYGGSNFFANKLEELAGIN------------ 342 baker's yeast
1709190  362 SICKQETE--EISGTLSPKFKIFTDILLSLRSLFERYKIMAANNVVELQRHVELNKEKLESMKGKPDV------------ 427 baker's yeast
10720283     --------------------------------------------------------------------------------     baker's yeast
19115109 584 ---NRSSKKRAENSLKSKKELYLKNLNQRYQIAHELEQELSYL-QDYVFSLGNPYVEYCK-----QHVKLEEESLKIWHT 654 fission yeast
19173623     --------------------------------------------------------------------------------     Encephalitozoon cun...
19114817 323 ---HNDTRLKRLEHVQSELQAVEQAIQEASAVHDAFNQRVREE-SKLFDSVRQSEMLSAIsdyanVHVEFFTNIRDLWIR 398 fission yeast
19113529 498 dnnVEVSRHNNIGRTAESVTHLTDMLLITTKDVAFVTDRVNFE-FQRYQDTHRQDLNRILnrltdSHIDWANRNLRIWNS 576 fission yeast
19112676 313 ---IPKFFKKKRYSLGQDDANPMELLQLSFQELCIFNEKLEQE-LNFLRERIDVEMRKTLqmvcdCHVEYFSGILEQHAV 388 fission yeast
19113272     --------------------------------------------------------------------------------     fission yeast
19075495 448 ----EGETSISKESLQQHKNTIENQLAAANWDCQKIDEFMDAE-LKFYKECQTSQWEEIIksvheCIYKWAQTNLQRWLR 522 fission yeast
19075429 497 ---QAKSQQKSLPYLEEQYEKYRAKAADLEKEFSESTTLLKRD-LSSLTTSRVDDLKASVetwleSAIESQKEIIERWES 572 fission yeast
6320090  553 vkyQETDPHTASINLKKEIEQLSESLEVTENDLEVISKVIKNDqLPKFSKEREVDLSEILkhysrYMRNYARQNLEIWKE 632 baker's yeast
6320633  538 kqlTEQERSKQIKQLNQDLSKLKDCLSICISDMLEINNSSYNS-LMHTYNHINLTIGKILklfaaSFKAWIKECLKNWKL 616 baker's yeast
1352971  343 ---QEASRREKINKLEGKITSLTGELENAKKVADGFEQECLKE-IDHFESVKTAEIKKSLgsladHHIEFYERILEAWEK 418 baker's yeast
1709190  428 ---SGAEYDRIKKIIQKDRRSIIEQSNRAWLIRQCILEEFTIF-QETQFLITRAFQDWAKlnsnhAGLKLNEWEKLVTSI 503 baker's yeast
10720283     --------------------------------------------------------------------------------     baker's yeast
19115109 655 LESDFSRL 662 fission yeast
19173623     --------     Encephalitozoon cuniculi
19114817 399 VKQ----- 401 fission yeast
19113529 577 VQESLKTY 584 fission yeast
19112676 389 KE------ 390 fission yeast
19113272     --------     fission yeast
19075495 523 TREELENL 530 fission yeast
19075429 573 FLDQ---- 576 fission yeast
6320090  633 VKRHQDFA 640 baker's yeast
6320633  617 AKLQIDEA 624 baker's yeast
1352971  419 VDDSL--- 423 baker's yeast
1709190  504 MDMPISRE 511 baker's yeast
10720283     --------     baker's yeast
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