7LTO


Conserved Protein Domain Family
Nse5

?
pfam08691: Nse5 
DNA repair proteins Nse5 and Nse6
Nse5 and Nse6 are non essential nuclear proteins that are critical for chromosome segregation in fission yeast. Nse5 forms a dimer with Nse6 and facilitates DNA repair as part of the Smc5-Smc6 holocomplex.
Statistics
?
PSSM-Id: 462563
Aligned: 16 rows
Threshold Bit Score: 181.616
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
7LTO_A        12 MDGALINSVLYVSPRNGA-----H-----YFVELTEKHLLAFEMLNSMCLLENYDHVLLFLECQ-------FgKSHNLAV 74 
Q756F5         1 MNASVGDHDMPSPSEAAVp----H-----YFVELNEHYLKDFEQFSSLCSLDEYEQLLYLLEEK-------F-VAGRVAI 63  Eremothecium go...
Q6CWU9         1 MASQSH-KYDLGRNELNKp----D-----YYVELTEKHLSDFEIWNSLCSNESYDMLLYLCEQY-------L-NMGRFPV 62  Kluyveromyces l...
XP_002171507   1 MASQHFSDAEIPDSQSSSgsstpS-----SPTSSPSSASSTSEALPAVSALLPTASRVRTRSARlrakrrcL-PTRSYVW 74 
O13688         1 MNASNNISKFPDLDNSSK----------------LIDHILDSDDSEELDELPDISSLVPSARAQsrkqylkN-DSSNSST 63  Schizosaccharom...
O94668         1 MNSALK-----------------------AIIELCIEEDLLPKSLDVLEYLLSTTSIPIP-------------------- 37  Schizosaccharom...
Q6FWW8         1 METVFDSENDE------------------PLVELSDVDDFEFEDGD---------------------------------- 28  [Candida] glabrata
EDO15214       1 MSDNSSSIHDSQDSDESV-----------TTIYNSNNHKIKDEKSTSKYPEVSDEEIDSDIDLYlidd------------ 57 
EDN63007       1 MGSVNSSPNEEFETVPDSqisgfDsplipTSVGSYFRDDDDDEKVHPNFTSDPENDSLNSDEEFsslensdL-NLSGAKA 79 
Q6CYC9         1 MLSNDEDEVVASSDDGLY-----------AKIWDIRDEELDDNGKNSDHFSDPGESFLLSSDDAml-------------- 55  Kluyveromyces l...
7LTO_A        75 IP----FDIILVLFTLSTL-SEYYKEPILRANDPYNTSR------ETLSRRALKLLQKYLAILKEFDSEQYNLYDLELLR 143
Q756F5        64 PP----GDVIVVLLTLATA-SSHYKADFVRANDPYNVGR------TDIAHRSMRLLSRLVDAVEEFDDRRYMRFELELLR 132 Eremothecium go...
Q6CWU9        63 IP----SEVIAVLFTLASI-GDHNKGSLIKKADPFDTGR------ELLTRRSMKLLETLLDILQTFDTDLYEIYDLELLR 131 Kluyveromyces l...
XP_002171507  75 S-----LDRLSKSAVKDAT-LSHRRKNVIQKLTHYGSAQsqgtrvASVEKAILKNLGMNESVLSSIKAEQDTQDAASEFH 148
O13688        64 YRw--nIDLLSSTATIDDS-VAKRRKLAVQNLLQYDSTQ----------------TFQTGDEIDELIGKSVGSNVLNVLR 124 Schizosaccharom...
O94668        38 ------ACYIRMCITLLVH-PEYPTSSNIQE-------ScnwilqQVVENRSKINFDAWSFENDLSDNDMPKENYLKIFS 103 Schizosaccharom...
Q6FWW8        29 ------DPILKKMKL-----DVKPESSSDSEg------------eVVLQETDVHPYMDFLQKLNKIQAGEVGEKRDIKRD 85  [Candida] glabrata
EDO15214      58 ---sedDEILLKMSSFNGS-SKKPAVIKNENgyi---------niKSFDLGDLYN-EKVTKNLNSIESAEDKINNEKKKF 123
EDN63007      80 ESgddfDPILKRTIISK---RKAPSNNEDEEIVKTPRKLvnyvplKIFNLGDSFD-DTITTTVAKLQDLKKEILDSPRSN 155
Q6CYC9        56 ----ptDRVLNNIMSSNAHiGTKRRRSTDREklw---------eeWHKSLKSSMEINNMTMELKSFTDKRPDVQASQRKN 122 Kluyveromyces l...
7LTO_A       144 CQFFLAIDTL------TPKKQKWGFDRFRRTKSESGvtyrqnasvdpELDQAKTFKNPYRSYISCLEQRNTILGNRLLNL 217
Q756F5       133 CQLFLFLDSIvp---kRPEVTIAKRVRTHGKNQPTDipfapdemplcVD----SLRSASYKYVSVLETKKAVFQNVLLTH 205 Eremothecium go...
Q6CWU9       132 CQFFYFIDSIrpengrALVLDPLNAQSSRATRRSFKlss-----rsaEGGSLLSVEPLYGSYINLIGDDTSVFKTTMVHS 206 Kluyveromyces l...
XP_002171507 149 YSYVGVVATG------EKSLWSSPKEEGRESSPVDVsslspsdvadfVCSGLLSFEDVVSQIF---------------TR 207
O13688       125 SNPIYDDDL-------RYEYCSNSKARVPDWNTLKAeclkdndlefnEGIIPTTFGDLLSAKLVPLDIALSICS---LQF 194 Schizosaccharom...
O94668       104 NQCLFTQDVDyw---dLIAYMSSRPPDLERWMSLMDiwlrileidaeENGSALMKKYMGEDLCELQDAIRICFSCFTLPQ 180 Schizosaccharom...
Q6FWW8        86 KSIVELQHEE------LVKQLKSAGTFTSVPDRLIDhissevlsdkfRDWHFITQECRDIDNT----------------- 142 [Candida] glabrata
EDO15214     124 VSKTFTKSN-------ELMAKLSKNFTNSQLSYYIDtiikdanpdkyLDWHFIEEDTTIDDISPILSFETAYYNCHDFNR 196
EDN63007     156 KSIVITSNTVa-----KSELQKSIKFSGSIPEIYLDvvtketisdkyKDWHFISKNCHYEQLMDLEMKDTAYSFLFGSSR 230
Q6CYC9       123 SPHY------------DRQKQIAYSIKRNIPTSLLTelaad-vsdstVDWYFLREDPDFSVVP-------SRYSTFLGKR 182 Kluyveromyces l...
7LTO_A       218 KLNEPGEFINMILWTLSNSL------QESTPLFLSS--HEIWMPLLEILIDLFSC----RQDYFIQHEVAQNVSKSlFVQ 285
Q756F5       206 VLSQNGGFWNCVAWTLSTMI-------DKDAVKNYC--GETWFPIVTFLFRLYEL----RHAYYMQYEMTQGISSAaYTK 272 Eremothecium go...
Q6CWU9       207 ALSQEGSFWNGFSWALSTFMigheneDQKTDWDYEL--AKAWLSVFKLIFIIYEL----RQDYYIDSKTETIEKS----- 275 Kluyveromyces l...
XP_002171507 208 FFENKGANCEEWAVCLQRCLdklsssSTKPILLPYI--SS----VLQAVVDMLGIdvgkRHTPVAHDSVRPPASTApSNY 281
O13688       195 FRSLGDTTCSEWIANLEKIFysykssSNNLNQIVRF--------IFETTADMIGIdlakRQVPIQLERTSASENLKsNLK 266 Schizosaccharom...
O94668       181 QTMES---------PFATSMskapakTESRGSN-----------SFEGTSRLANLg------------------------ 216 Schizosaccharom...
Q6FWW8       143 --------------TLSSMLdafgvgNSADLLNLKIi-ASEYTKKYDSLSTIYPVgymlEELVDYYRRTLPRAETPlE-- 205 [Candida] glabrata
EDO15214     197 IRHEILKSYP----NLNYILptfgisKEKLNSINDGyfCISDYYNYDNLCTILPTdsmkSIIIYYIDEPN---------- 262
EDN63007     231 SQGKVPEFVHLKCPSITNLLvlfgvnQEKCNSLKINy-EKKENSRYDNLCTIFPVnkmlKFLMYFYSDDDNDDVREf--- 306
Q6CYC9       183 LSI-----------PLDDLYkkfgadLRANIEYTNC-----------PYGKLIPVetmcGLIESNNSDSVQ--------- 231 Kluyveromyces l...
7LTO_A       286 rlsE----SPLAVFFESLNTRNFANRFSEYV--FLNCDYKLPSDNYATPVHPVYNG--ENTIVDTYIPTIKCSPLYKSQK 357
Q756F5       273 ---Ela-dSPLVLLFKSLGSNNVHITLCDYL--FVNCGKNV----GRGEARPVYHS--ELKLSATYVPFCKPSTEWKLFK 340 Eremothecium go...
Q6CWU9       276 ---------PIFRLLEAVDKKNQLKGLVQYL--FVGCVECE-------ILYPVSPSlnDPSTSNASFNQFHEDKDYRAAF 337 Kluyveromyces l...
XP_002171507 282 ---SvaatVKLLTLLYPLCELPLQKDIVADL--CRIALDTAVSDDVRLVIMDAFASilKVPRATHSRTRSRSSDDAWQIL 356
O13688       267 ---I-----KVINFLKCCGTLYRFSDDTVRFemIQDACRILIDNQVGSFCKWQFSQfmELPISLNPDFLISNIHKVSES- 337 Schizosaccharom...
O94668       217 --------aKLLCLIWAMLPKGRF--FVVHLtdAFHFLSKLDERFSKLNAKQQDLFfgNLGASNLRYCLSQYI------- 279 Schizosaccharom...
Q6FWW8       206 ---------YCHAFFLFVLDIKIYDSHECDTswCEEVLDILTQRFRQEEIFDVYLKvvELNDYYMHYRVTKLIPRMKSY- 275 [Candida] glabrata
EDO15214     263 ---------FVKFFLCFILDKKIYESNDCDSkwCEEIVSALD-----VDVIEEYLKliNLDDYYMHYRLTKLLPSFKNK- 327
EDN63007     307 ---------FLKAFICLILDRKVFNAMESDHrlCFKVLELFNE----AHFINSYFEivDKNDFFLHYRLLQIFPHLQSA- 372
Q6CYC9       232 ---------AFKHFIKFILDRKI--SGNLKTkwVINMWNRFT-----CDKLSVYFEvtPRNFYLMHYRLTRLIP-IESE- 293 Kluyveromyces l...
7LTO_A       358 SLALRRKLIGSCFKLLLRVPDGHRLITPRIVADDVIQGISRTLASFNDILQFKKFFmtenlsqesyfipLLAEGTLSEIL 437
Q756F5       341 SMQLRRRILSCYFKVLADIPKDHRIK--PFSEDQSIKYMVRTLLELETVEMFQAFFftddlkitmhylpLLAEHIIVVLL 418 Eremothecium go...
Q6CWU9       338 SMDVRKDTLCVFVRFLDRYER--HLQSYPFTLDALYGTIVDALYSDLKISSFKQFFlscdvekdrnlitTLVEKLLNKAF 415 Kluyveromyces l...
XP_002171507 357 YETTTNAQAWVTLLMLLPNRKGIIRNRQKLALSWFLSKPLQSINNNNDNASLFAEV-------------CEAIEALPNKT 423
O13688       338 --------PRVWVTILSSLSRSCQKFRKKIAFTLFVGKQSKN--DDSDFSSLCQRL-----------------DEISASC 390 Schizosaccharom...
O94668       280 --------------LMKGIGIGINIRHTRCEFTKQLTQLLPTSLPKNKIRQKLHLR------------------------ 321 Schizosaccharom...
Q6FWW8       276 --------------ILAKLFGTVD--------TVTIVNEFNTLLDDKRYKELLYFL------------------------ 309 [Candida] glabrata
EDO15214     328 --------------LVDGIFGDNTLA------LNRIIDEFNTIFDDKEYRKLLYFS------------------------ 363
EDN63007     373 --------------LLRRRFSEKQGRTETI--QQNIIKEFNEFFDCKNYKNLLYFI------------------------ 412
Q6CYC9       294 --------------IVSKLFPN----------DNDVITEFENLLDSQEWTSLLYFI------------------------ 325 Kluyveromyces l...
7LTO_A       438 KDTQECVViL---TLVENL-SDgVSF--CN-EVIGLVKSkcfAFTEQCSQASYEEAVLNIEKCDVCllvLLRYLL--HLI 508
Q756F5       419 EDCGKAIE-S---TLVTNLgNL-DVV--IE-NIEEYLEM---RPVDCSNAIGLHKTVFYI---DTC---TLVLIKy-AIL 480 Eremothecium go...
Q6CWU9       416 SNVEPRRT-FnivNKMSNFeEV------TS-ELMKLLRA-----IDRSAAFNRSRISKRRIQMDFC---IIILTR--LII 477 Kluyveromyces l...
XP_002171507 424 AEDFVRVR-YsisALFFAFhGElAPQ--PD-EVLRLLALl--RKLDHSIHGTTTDSLMLLRCEAKD---VVQRLYlyVYY 494
O13688       391 NNDYTTLL-YqirTFGYAVdEKhFKT--NE-RLECLLEKl--RKIDLTISGSTDHLLLSRCEVKDC---IHRLFMvlYYL 461 Schizosaccharom...
O94668       322 -------------AWVSFLgSAlRES--DR-NFDKELFY---TTLKQLYTMYQQTELVGIDRPMAI-------------- 368 Schizosaccharom...
Q6FWW8       310 ---------------LLVLgTRyVPRgkN--ETIKYFIS---CVTDVYDDSQ-SNPEISI-------------------- 348 [Candida] glabrata
EDO15214     364 ---------------IFIFgSDlVPYskESlPVIDYIFN---CIRDVSDMTNVADIELLL-------------------- 405
EDN63007     413 ---------------LTMYgSKfIPFgpKC-QVTEYFKD---CILDISNETT-NDVEISI-------------------- 452
Q6CYC9       326 ---------------ILVLgTSaLPFgpS--PRMTYIKD---CILDLNSQNS-SKIQLSI-------------------- 364 Kluyveromyces l...
7LTO_A       509 GTEAILDAKEQLEM------------------------------------------------LHAIEK 528
Q756F5       481 LHGTDVLLTGGLDMa-----------------------------------------------LKRFFK 501 Eremothecium gossypii
Q6CWU9       478 TTHPQGNFEELLRV------------------------------------------------LTTFAK 497 Kluyveromyces lactis
XP_002171507 495 EHCNAYQVLEQAADmnmnvsaadlqddiiaptakseavtagdikvavkdnleaeteeepkseVKAEAK 562
O13688       462 NTNSAPELERI---------------------------------------------------IESDLP 478 Schizosaccharomyces pombe 9...
O94668       369 --------------------------------------------------------------LKDMLV 374 Schizosaccharomyces pombe 9...
Q6FWW8       349 --------------------------------------------------------------IKNYLL 354 [Candida] glabrata
EDO15214     406 --------------------------------------------------------------LKSILT 411
EDN63007     453 --------------------------------------------------------------LKGILN 458
Q6CYC9       365 --------------------------------------------------------------IKAYLT 370 Kluyveromyces lactis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap