Conserved Protein Domain Family
Lipase_2

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pfam01674: Lipase_2 
Lipase (class 2)
This family consists of hypothetical C. elegans proteins and lipases. Lipases or triacylglycerol acylhydrolases hydrolyze ester bonds in triacylglycerol giving diacylglycerol, monoacylglycerol, glycerol and free fatty acids. Lipase EstA is a extracellular lipase from B. subtilis 168.
Statistics
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PSSM-Id: 396304
Aligned: 14 rows
Threshold Bit Score: 231.469
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q19310        42 KEPVIFIHGSGdtal-ftqQPLAtGFSRSIQYFLEQN-YTEAELYATTWGDTWGsGSMLDTYstihTCGNLIYLRRFLEA 119 Caenorhabditis ...
O76556        63 QNPVIIVHGIT--------NKAS-RFGGTVAYLKSKG-YKNSEIYGTTWGDSGR-TPVGLVDm---KCNYVKQIRAMIIA 128 Caenorhabditis ...
O62271        64 NQPLIIVHGVS--------DTAGeKPFWAAQWFRKEGkYAENEIYSTTYFNGAQgNPLKWIEys-mKCEYIKQVRSLIVA 134 Caenorhabditis ...
Q19941        63 NDPVIFVHGVS--------DIAGgKMQALSATYKKHG-YGSGELYATTYDSGSKnNPIAWADys-lKCEHVKQIRTFILA 132 Caenorhabditis ...
Q23548        63 DRPVVFVHGLN--------N-EAgSLWKIARDFTNAN-YPRQYLFATTWGKGTEpLNLNVAM----SCTHVQHVRRFIET 128 Caenorhabditis ...
2_pfamImport   1 HSPIVFIHGNSdsalkygnDQYQsGWDTVVQYFMDRG-YTLAELYGISYGDRNMtQSVFRVF----NCQDLLLHRQLLLS 75 
Q20437        67 NTPIVFIHGNSdsalkfgdGPFQsGWDEILKYFMSKD-YTLAELYGITYGDRNIsNSYIRHF----NCQNVQLHRRFLEF 141 Caenorhabditis ...
O16380        83 KTPVIFIHGNSdsa--lktSSMAtGWDNTISYFSTQG-FTSAELYATSWQDTNSlKAETRTH----DCKDLTRLRKFFEA 155 Caenorhabditis ...
Q22060        67 NTPVVFIHGNSdaal--hvssAAtGWSNSIEYFLEHG-YTVAELYATSWQDTNAlHAASRTH----NCKDLVRLRKFLEA 139 Caenorhabditis ...
Q19462        62 GLPIVVIHGLA--------GYAGlSKKSLLNKYYSYG-QPKGTVFATTYARGKLmDSLQHGM----QCDYVLKVRTLILA 128 Caenorhabditis ...
Q19310       120 VIGYTGAkKVDIIAHSVGVPLMRKVVKGGtlIGT-DGNCTLGPPLGAKVDTFLGIAGPNFGLCVCQLAQ----------T 188 Caenorhabditis ...
O76556       129 VRQYTGQ-KVDVIGYSMGSPLARKAILGG--QCV-DTREILGAPLTELVDTFLSVAGANYGSVLCILPVp--------vG 196 Caenorhabditis ...
O62271       135 VRLYTGR-NVDVIGFSLGVPVSRKAILGG--RCV-DTGEYLGEPLTRVVDTYIGVAGPNRGASPQLGPLsvpa---calS 207 Caenorhabditis ...
Q19941       133 VKYYTQR-NVDVVAYSLGVPIARKAILGG--ECV-DTREDLGQPLTQYVDTFVGVAGPNHGISLQVAGVsipgcvigaiP 208 Caenorhabditis ...
Q23548       129 VLKYTGAqKIDVIGYSMGSPIARKAILGG--KCVdNPNVALGPSLHSRVHTYISVAGANQGSQLCALP------------ 194 Caenorhabditis ...
2_pfamImport  76 VLVYTGArHIDIIAHSMGVSIARAIIQGGkfTSE-KESCDLGSDFSSLIGTFIAISSANYGMCSCEAg-----------T 143
Q20437       142 VLHYTKAkQINIVAHSMGVSIARKAIQGGefVTK-TESCDIGPNLSHRIGTFIALASANYGMCPCQHa-----------F 209 Caenorhabditis ...
O16380       156 VLAYTGYaKVSVISHSMGVTLGRKVIQGGivNGT-DGNCNLGVSISGKVDVFVGIAGANYGLCGCAGTVg---------L 225 Caenorhabditis ...
Q22060       140 VLAYTAApKISVVTHSMGVTLARKIIKGGsvSAS-DGSCDLGLPLNKKVEVMIGISGANYGLCNCEG-Gs--------aT 209 Caenorhabditis ...
Q19462       129 VHEYTQK-PVNIIACSMGSPITRKAILGG--HCV-DSGVNLGRPINHLIHNYVSVGGANHGAIMCAKQP----------F 194 Caenorhabditis ...
Q19310       189 VpawCNALDGLYpgytCqdqlwcgyt---sgsckqenYSNLLQKTNDDPNRE-GDHVYAMWSDVDEVLLnrGMVWGKPTA 264 Caenorhabditis ...
O76556       197 T---CNKKNGLH----C--------------------DSEFLQDINNQHRYE-GSHVFSIFSTADEKIG--FRSCGRPVS 246 Caenorhabditis ...
O62271       208 ItpiCNSVNGLYsg-nCp------------------aQSEFLQDINKFAHYE-GQYTYSIYTQKDQMVG--YTVCGQLTS 265 Caenorhabditis ...
Q19941       209 IlpiCSRVIGLYsg-lCp------------------tESDFLTDINEKNHYE-GKYVFTLYTETDEWIG--YKICDKITA 266 Caenorhabditis ...
Q23548       195 FfdiCNMKTGLM----C--------------------NSKFLEDINWFKNYEgSYKAFNLASTADFVVG--YMACGKKAS 248 Caenorhabditis ...
2_pfamImport 144 AfpaCDKEIGFFpg-yCprqncsspsikigaqcyktkYSKFLTKLNKVHKKE-AEFIASIWSKDDEVFLkgNLVWGKQTS 221
Q20437       210 AfpaCGMETGFFpg-tCpemtcssqdvnisetcgevpYSNYLMNLNNSGKKD-ASFVASLWSDDDEILGkgNMVWGRQTS 287 Caenorhabditis ...
O16380       226 FaptCNKKNGFWpgdsCggytssfcgysstpcngiskYSNLLNDMNNSNKKE-ASYIFSTWSKADDLIGnsDIVWGRPTS 304 Caenorhabditis ...
Q22060       210 LektCNRVNGLWpgdsCglnyldcgltplpwpcsgvnYSSFLMQLNADKNKE-GDYVFSMWSLSDDLIEygTQVWGRSTC 288 Caenorhabditis ...
Q19462       195 VngiCSLTHGLD----C--------------------RSKFLQEINSQPFQY-GKNMFAIYSVADEVIGl-RNTCGEMSS 248 Caenorhabditis ...
Q19310       265 RIPGMNGRWISDRNGHVAMKDLTELRQFE 293 Caenorhabditis elegans
O76556       247 PIRGGTGFVKRDGLNHDQLMDTTHPLQRN 275 Caenorhabditis elegans
O62271       266 PLPGQNGQRVYTDKNHDQVFDDTHEVQLR 294 Caenorhabditis elegans
Q19941       267 RIPGEDGHRIYKKYSHDEIILRTCDTQIE 295 Caenorhabditis elegans
Q23548       249 EFTGAHEWK-VEGRNHEQTEFDTAAIQLQ 276 Caenorhabditis elegans
2_pfamImport 222 LVPGSNIWKEYPQLTHMETKTETAADQFK 250
Q20437       288 LVPHSDMRKIYSDLKHNDVKLLTAEDQYN 316 Caenorhabditis elegans
O16380       305 LIPLSDGKIIYEKLTHMQSKENTAIDQYK 333 Caenorhabditis elegans
Q22060       289 FIPTSDGKVVYHVYTHMETKELTYVDQYQ 317 Caenorhabditis elegans
Q19462       249 PLEGATSIV-KTRLMHGAVIGGTTEDQWR 276 Caenorhabditis elegans
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