3ADD


Conserved Protein Domain Family
KTI12

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pfam08433: KTI12 
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Chromatin associated protein KTI12
This is a family of chromatin associated proteins which interact with the Elongator complex, a component of the elongating form of RNA polymerase II. The Elongator complex has histone acetyltransferase activity.
Statistics
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PSSM-Id: 400643
Aligned: 18 rows
Threshold Bit Score: 244.127
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3ADD_A        13 LIILTGLPGVGKSTFSKNLAKILSK---------NNIDVIVLG-SDLIR------ESFP--VW-KEKYEEFIKKSTYRLI 73  Methanocaldococ...
Q86H29         3 LIVLSGPPCSGKTTRAKELYEHFTN---------LGKKVIIIN-EESLLi-----NKNEg-YK-DSLTEKMTRGSLKGAT 65  Dictyostelium d...
O46079         3 LVVITGLPASGKSTRARQLRDHFVE---------RGRKVHLISeNEAVPka--gfGKNS--HTgDSQKEKVVRSDLKSEA 69  fruit fly
Q7Q9K5         3 LIVITGLPRSGKTSRAKELEKYFTEl--------GKGPVHIVS-EADCIarsgcgVKES--FT-DTGKEKQIRASLKSEA 70  Anopheles gambi...
Q5I0L7         3 LVVVCGLPSSGKSRRTEELRRALTG---------EGRSVYVVD-DASVLg-----AQDStvYG-DSAGEKALRAALRAAV 66  Norway rat
1_pfamImport   3 LVTITGFPCSGKSTRAQQLKQYFEKrlkepeydgPALEVVVVD-DESSHv-----PRST--YD-SSAQEKPGRASLFSNV 73 
Q6FME7         3 LVLMCGFPLSGKSTVARELAGYLRE---------KGANVVVHS-DETLGhkgretREED--YN-DTHAERKLRNEIMSAV 69  [Candida] glabrata
Q96EK9         3 LVVFCGLPYSGKSRRAEELRVALAA---------EGRAVYVVD-DAAVLg-----AEDPavYG-DSAREKALRGALRASV 66  human
Q6LX62         2 LIILTGLPSVGKSTFSKAFSKKMAE---------KNIDNIILG-TDLIR------ESFP--VW-KESYEEFIRDSNNYLI 62  Methanococcus m...
Q9LMH0         3 LVVICGQPCSGKSIAAVTLAETLKEs-------eTKQSVRIID-EASFHl-----DRNQn-YA-NMPAEKNLRGKLRSDV 67  thale cress
3ADD_A        74 DSALKN-YWVIVDDTNYYNSXRRDLINIAKKYNKNYAIIYLKAS-----------------LDVLIRRN-----IERGEK 130 Methanocaldococ...
Q86H29        66 DRNLSKdTVVISDSLNYIKGYRYELYCIARAAGTRLLVLYCNTP-----------------RDLAKKWN-----QERDQS 123 Dictyostelium d...
O46079        70 SRHLNQeDLVILDAGNYIKGYRYELYCMSKVSRTTQCTVFTCIP-----------------QEEAWTFN-----SQRTAP 127 fruit fly
Q7Q9K5        71 MKLLTKsTLVIMDGTNYIKGYRYEIFCMSKNARTTQCTVHCAMT-----------------VEQRNARR-----EEIVQS 128 Anopheles gambi...
Q5I0L7        67 ERRLSRqDVVILDSMNYIKGFRYELYCLARAVRTPLCLVYCIRPgwpsrglpvpgacessdPAVSVSWRpradyGEKTQA 146 Norway rat
1_pfamImport  74 NRSLGTdTITIVDSANYIKGFRYQMYCAAREAHTRVATIHVVAP-----------------PDMCRKWH-----EKRGEC 131
Q6FME7        70 RRDLSRsTIVIVDSLNYIKGFRYQLHCECKNSNTGFMLVHCMAT-----------------YADILKRD-----ENGEES 127 [Candida] glabrata
Q96EK9        67 ERRLSRhDVVILDSLNYIKGFRYELYCLARAARTPLCLVYCVRPggpiagpqvaganenpgRNVSVSWRpraeeDGRAQA 146 human
Q6LX62        63 KEALENkFSVIVDDTNYYNSKRRDLMNIAKECDTNYVTIYLKAP-----------------LNLLLKRN-----IERGQK 120 Methanococcus m...
Q9LMH0        68 DRSVSTgEIVIVDSLNSIKGYRYELWCIARAAGIRYCVVYCDVD-----------------EAHCRQWN-----KERSDR 125 thale cress
3ADD_A       131 ---------------------------------------------------------IPNEVIKKXYEKFDEPGKKYKWD 153 Methanocaldococ...
Q86H29       124 v-------------------------------------------------------aYSEKLLDELTNRFEVPNPKNRWD 148 Dictyostelium d...
O46079       128 delpgdserv--------------------------------------qpvdnsdvpYTRETFDALCQRYEEPQSNNRWD 169 fruit fly
Q7Q9K5       129 sss----------------------------------------------------geLDAETFDALCQRYEEPQDTSRWD 156 Anopheles gambi...
Q5I0L7       147 vgaveqraisplanggvptavpkeldp----kdilpsnppavmtpeseksaepapcaFPPELLESLALRFEAPDSRNRWD 222 Norway rat
1_pfamImport 132 s--------------------------------------------------------YKQATFDNLIMRYEEPSSMVRWD 155
Q6FME7       128 p-------------------------------------------------------rWGKELLDQLIQRFEEPDASNRWD 152 [Candida] glabrata
Q96EK9       147 agssvlrelhtadsvvngsaqadvpkelereesgaaespalvtpdseksakhgsgafYSPELLEALTLRFEAPDSRNRWD 226 human
Q6LX62       121 ---------------------------------------------------------IPNEVIKNMYEKFDTPGTKYAWD 143 Methanococcus m...
Q9LMH0       126 ge-----------------------------------------------------dgYDDGIFEDLVRRFEKPERRNRWD 152 thale cress
3ADD_A       154 EPFLIID------TTKDIDFNEIAKKL-------------IEKSKEIPKFYVLEENKnKNNNISDKIDKETRKIVSEYIK 214 Methanocaldococ...
Q86H29       149 SPLFTLE------PQHTLPHELLFKTL-------------FEVQELRPNYATQSQSL-SPANFVHELETKTQEITSVISD 208 Dictyostelium d...
O46079       170 SPLVVVL------PKDTLDMEAIYKAL-------------YESQPLPPNQSTYNAPL-GTTNYLFELDKIVQAIIKEILG 229 fruit fly
Q7Q9K5       157 RPLFTVY------GGEEMELARIHSAL-------------YEQAPLPPNLATQNMPL-SATNFLFELDKSTQTIIDQIAA 216 Anopheles gambi...
Q5I0L7       223 RPLFTVVg-----LEEPLPLAEIRSAL-------------FENRAPPPHQSTQSQPL-ASGSFLHQLDQATSQVLTAVME 283 Norway rat
1_pfamImport 156 SPLFTVP------WDEDPPFEDIWNAI-------------IKGDKKPPTSAVLQRSK-PPPNTLQTLTATTSLINSSLLS 215
Q6FME7       153 SPMATVVspetllPTHKQLVDQVLLGIsdksssrngspspGPMNRLSQNNPTLLKAA-TGADFVRLLDAKLTETVRIIVR 231 [Candida] glabrata
Q96EK9       227 RPLFTLVg-----LEEPLPLAGIRSAL-------------FENRAPPPHQSTQSQPL-ASGSFLHQLDQVTSQVLAGLME 287 human
Q6LX62       144 LPDITVD------TTEKIDYNEILNEIle----------iNENKNLKIEEDKIPKSE-PVESDLVKIDSLTRNIVGNLIK 206 Methanococcus m...
Q9LMH0       153 SPLFELYpsr-evIDKSSPV--ILEAVtyltkt--vdsktQDVRILQPSIATQAARF-SEANSLYELDRATQEIINAIVE 226 thale cress
3ADD_A       215 ----SKKLDKDK-----------------------------IKEVVELRKEF--LKKIKk-------XEEVDADRVLKEF 252 Methanocaldococ...
Q86H29       209 alqsSMVGDYIKvpgtekrv--------------vihsklnLVELRNQRRQF--YKFAQ--------LHPPQPHLIADSF 264 Dictyostelium d...
O46079       230 av-kIKAFGQLRipgsrnpv--------------kvatsmnALQLNRLRQKF--ITSTCha----sqTSPTPLEQVPHLF 288 fruit fly
Q7Q9K5       217 ar-kIGLDGPVEipqagmra--------------evpanmsVAQLNRHRRQF--LNYVKmh-----tNVSSDISKIPAIF 274 Anopheles gambi...
Q5I0L7       284 aqksAVPGDLLTlpgttehl--------------rftrpltLAELSRLRRQF--ISYTKm------hPNNENLPQLANMF 341 Norway rat
1_pfamImport 216 hltsLPNSTTFPipsppapssss-------lvlhlpakkitLSEMSRLKRQYetVQVKAqasgglaaAGNWTEGDVATGY 288
Q6FME7       232 ecqaAQAIGGPQriivsedvrdinddrclfldipadapqltLPRLNRLKRQF--VQMNKn-------LRDVDLERAAPLF 302 [Candida] glabrata
Q96EK9       288 aqksAVPGDLLTlpgttehl--------------rftrpltMAELSRLRRQF--ISYTKm------hPNNENLPQLANMF 345 human
Q6LX62       207 ----TGKIDKKD-----------------------------IKLLSEIRKSF--LKDCKki-----eSEKLDFEKIEKDF 246 Methanococcus m...
Q9LMH0       227 qqslGAAISRVTlgnelppi--------------eicrpigLPELRRLRRTF--VKLMGqssl-sgpPLPTDADSAKRRF 289 thale cress
3ADD_A       253 KDLLN 257 Methanocaldococcus jannaschii DSM 2661
Q86H29       265 VDFLN 269 Dictyostelium discoideum
O46079       289 VQFIN 293 fruit fly
Q7Q9K5       275 VQFLN 279 Anopheles gambiae str. PEST
Q5I0L7       342 LQYLN 346 Norway rat
1_pfamImport 289 VRFLE 293
Q6FME7       303 VAYIG 307 [Candida] glabrata
Q96EK9       346 LQYLS 350 human
Q6LX62       247 LDYLN 251 Methanococcus maripaludis S2
Q9LMH0       290 VDYLN 294 thale cress
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