Conserved Protein Domain Family
F420_MSMEG_4879

?
TIGR03564: F420_MSMEG_4879 
F420-dependent oxidoreductase, MSMEG_4879 family
Coenzyme F420 is produced by methanogenic archaea, a number of the Actinomycetes (including Mycobacterium tuberculosis), and rare members of other lineages. The resulting information-rich phylogenetic profile identifies candidate F420-dependent oxidoreductases within the family of luciferase-like enzymes (pfam00296), where the species range for the subfamily encompasses many F420-positive genomes without straying beyond. This family is uncharacterized, and named for member MSMEG_4879 from Mycobacterium smegmatis. [Unknown function, Enzymes of unknown specificity]
Statistics
?
PSSM-Id: 274651
Aligned: 12 rows
Threshold Bit Score: 314.291
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_011606486  15 ILERAHEAAEAGVDTVWFSQGLD-I-DAITVSALVGREVPGIGIGTAAVPMYQRHPLVTAAQARTAQ-I-ATDGRFLLGI 90  Frankia alni
WP_011209157  19 LTDELRRNADEGFDSSWLTHVFG-V-DALTALAVAGSRVPDIAIGTAVVPTYPRHPGALAQQARTTAlA-VGPDRLTLGI 95  Nocardia farcinica
WP_011730159  21 LAADIQWAEAAGLDSAWMPQVPDdF-DCLSMVALMAAHTSTIELGTAVVPLQAQHPVALARQALSVH-A-IAEGRLALGV 97  Mycobacterium s...
WP_011725408  20 VIAQARRAHELGVGQVWLAQQQS-Y-DAIALAALVGAAVPGLGVGTSVVPINPRHPLIVASLAQTAQ-A-AAHGRFSLGL 95  Mycobacterium a...
WP_010948951  22 LVDDAATAERGGFTAFWMPQVPG-YlDALTAVALIGQATERIEIGTAVVPIQTRHPMALAQQALTTQ-V-ACGGRFTLGI 98  Mycobacterium a...
WP_011605543  25 VLDQVRTAARAGLDSAFLGQLVS-W-DALTLAALAGAAVPGIELGTAVVPTYPRHPLALAGQALTVQ-A-VAPAGLTLGI 100 Frankia alni
WP_010982218  19 TVRLAHEAAAAGLRSAWFGQTFG-A-DSPQLAAVVGREVPGLHVGTSAIPVFGRHPLLVSSQAQTAQ-A-ATHGRYHLGL 94  Streptomyces av...
WP_011730748  22 LIADARRAHDIGVKQIWLAQQAD-I-DAIAAAGLIGAAVPGLGVGTAVVPINPRHPLVISAAAQTAQ-A-AAHGNFTLGL 97  Mycobacterium s...
WP_011602800  50 LVARARWAAGTGLASLWLGQGYG-L-DALTALALLGREIPETALGTAVTIIPGRHPIALSSQARTTQ-A-ATGGRLRLGL 125 Frankia alni
WP_011606461  24 laaiartvaaaGVSTAWLPQGYG-Y-DSIGVLTAVAREVPGIELGTSVVVVQPRHPRVLAGQALTAQ-A-AAHGRFTLGL 99  Frankia alni
WP_011601818  22 LVGQAKAAAAAGLGSVWLGQQYD-L-DALTALAALAVHVPGVGLGTAVTVTHSRHPITMSSQAQTVQ-A-ASGGRLTLGL 97  Frankia alni
WP_011562309  15 IVAHAQRAEADGFSSLWYASAVG-G-DPLVAMAIAGRATGSIELGTAVLQTYPCHPLLQANRVAAAA-NaMGRPGLTLGL 91  Mycobacterium
WP_011606486  91 GLGNRAVVEDAFGVPFERPIRHLRDYLRVLRSVFET-GAADVQGPTVTARL-P-TtSptGPrtGVT-PaIPLLVAAMGPQ 166 Frankia alni
WP_011209157  96 GLSHQMVIENMYGYDFARPVRHLREYLEVLMPLVDG-QPVSFSGETVSANL-Q-L-S--VP--NDD-R-VPVLVAALGEQ 165 Nocardia farcinica
WP_011730159  98 GPSHHWIIRDMLGLPYDKPAAYTRDYLEVLNASLAGpGPVDVENDTFTVHN-P-Ta---LA--AET-P-LPVLVAALGPV 168 Mycobacterium s...
WP_011725408  96 GLGAADLERRTFGTEWPNTITRLREHLTILGSVFHS-GAVDFHGSELSAAP-S-F-PvrVP--GGT-P-IPVYVAAMGPK 167 Mycobacterium a...
WP_010948951  99 GPSHHWIVNGQLGLPYERPARLTRNYLQVLGAAFAGpGSVDVDNESYCVHS-Pv----dVT--DSF-G-VSILLSALGPT 169 Mycobacterium a...
WP_011605543 101 GPSHQQIIEGQFGYRYDRPARHIREYLTALRPLLRG-EAVDVHGETVTAVG-Rv----dAP--VAV-A-PSVLLSALGPV 170 Frankia alni
WP_010982218  95 ALGTKLLTEAGFGIPFERPIARLREFLTALRQLTET-GAADFHGELLTAAT-P-I-SarVP--GAE-GgVPLLVAAMGPQ 167 Streptomyces av...
WP_011730748  98 GLGARVIEHYAFGIDRTNTVNRLHEYLQVLRGAFER-GDANFRGAEYSIEL-Q-W-PvqVA--GGT-P-IPIYVAAMGPK 169 Mycobacterium s...
WP_011602800 126 GSGHRASVEQRYGLPFDRPALRLREYLAALLPLLRE-GAADVRGETVTAVTgG-V-DarVA--GAA-P-PPVLVAALGPA 198 Frankia alni
WP_011606461 100 GVSHPGLLE-IYGQPFHRPVAALRTHLDTLLPILDG-RRV--PGATGIGSD-P-A-GsaVP--GAGvR-VPVLLGALGPT 169 Frankia alni
WP_011601818  98 GVLHRRPVARRFGIDLDGPATYMREYLCALQPLLRD-GTVVFEGDMITADT-SgF-SghVA--GST-P-PVVLVAALGTA 170 Frankia alni
WP_011562309  92 GPSHEPIVRDVLGLSYDHPARNTREYLRIVSGLLAG-VEVDFDGTDWSTHS-Ag----rMA--ALD-HrVPVLLSALSPR 162 Mycobacterium
WP_011606486 167 ALRAAGELADGTLPYLAGPRTLAESIVPTIVGAARAAGRPAPTIAVGVPAAV--TADVAGTRAHAERTLAAYGNVPSYRA 244 Frankia alni
WP_011209157 166 MLRLAGKRTDGTVLWMTGPTTIRDHIAPTITAAATEAGRPAPRIVCALPVLV--TDDPDGARERAAKVFKIYGSLPSYRA 243 Nocardia farcinica
WP_011730159 169 MLQIAGELADGTVLWMADERAIGDHIAPRINKAADNAGRPAPRIVAGIPVCLcaNSEIDTAKERANRILAEAETSPNYQR 248 Mycobacterium s...
WP_011725408 168 ALQVTGELADGTLPYLAGPRTIEEFIVPRITKAAAEAGRPAPRIIAAVPVLL--SDDVEGARAAAAQQLSFYETIPSYRN 245 Mycobacterium a...
WP_010948951 170 MLQLAGERADGTILWMADERAIGDHVVPRITAAAGGAGRPAPRVVAGVPVAVcsNSEIDDARAYAGEMLGHAEFSPNYVR 249 Mycobacterium a...
WP_011605543 171 MLRVAGELADGTVTVWTGPRTIGDHIAPTIAKAAADAGRPAPRVVCSVIACV--TADPDQVRTAVAAQVGFASDLPSYRA 248 Frankia alni
WP_010982218 168 ALRASGELADGILPYLAGPRALDEHIVPAVTAAAEAAGRPAPRIVAMVHGVV--TDDADSVREKAVEQLAFYEQIPSYAR 245 Streptomyces av...
WP_011730748 170 ALRITGEYADGTLPYLAGPRTLSEFIVPTINDAAEAAGRPQPRVTAMVPVVL--SDDAETARRTAAEQLAFYATIPSYQK 247 Mycobacterium s...
WP_011602800 199 MLRVAGEVADGTVTWLAGARTVGEYIVPAITDAA--AGRAAPEVAVGLPVCV--TDHPDEVRERAAGALALFDSIPSYRA 274 Frankia alni
WP_011606461 170 MLRLAGERTDGTITFLAGPRTIGDHVVPLIGAAARDAGRPAPRVVVGLPVAV--TSAPDRIRTELDAEYADYAALPSYRT 247 Frankia alni
WP_011601818 171 MLRVAGELADGTVTWMAGPRTIGSHIVPAITAAGGGA--AAPQVAVSLPVCV--TDHPEEARRRAAAHLACYADLPSYQA 246 Frankia alni
WP_011562309 163 MLRIAAEFADGVVLWMASASAIAGRIAPVLREAANAQGKPAPRIVAGLPVAV--HDDADEARAAISATASSYERMTNYQN 240 Mycobacterium
WP_011606486 245 VLDAEGAIHPADLALIGDEDAVAAGIRRYLDAGATDVRI 283 Frankia alni
WP_011209157 244 MMDREGAAGPADLAIVGTEDQVAERVRTVFAAGATEFVG 282 Nocardia farcinica
WP_011730159 249 LLDRGDARNVGDLCAAGDEDAILARFKRFADAGVTDLSV 287 Mycobacterium smegmatis
WP_011725408 246 VIAREGLSNAVELAAIGPEESVLRQVRRYFDAGATDVVL 284 Mycobacterium avium
WP_010948951 250 LLQHGDAEDVGDTMAAGDESAVLRRLRRYRDAGATDLAA 288 Mycobacterium avium
WP_011605543 249 ILDREGLGGVHETVVAGSAEVVERAMRRYADAGATELLV 287 Frankia alni
WP_010982218 246 VIELSGGQRAADVSVIGDERRVAAEVRRYRDAGATEVVF 284 Streptomyces avermitilis
WP_011730748 248 VIAREGISDLTELAALGSPDQVREKLQSYLDAGATDVVL 286 Mycobacterium smegmatis
WP_011602800 275 VLDREGVVTAAEVAIIGDERQVERELGRLAAAGATHLLA 313 Frankia alni
WP_011606461 248 ALDRDGFTQPGAIAVVGDEDAVVDQLAAYHALGATDVLV 286 Frankia alni
WP_011601818 247 MFDQEGAANPAEVAIIGDERHLETQLHRLTDAGATRFIA 285 Frankia alni
WP_011562309 241 IIRAGGGERAADVGIVGDEGAVARQLAELIDAGATDVWA 279 Mycobacterium
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap