Conserved Protein Domain Family
GPDPase_memb

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pfam10110: GPDPase_memb 
Membrane domain of glycerophosphoryl diester phosphodiesterase
Members of this family comprise the membrane domain of the prokaryotic enzyme glycerophosphoryl diester phosphodiesterase.
Statistics
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PSSM-Id: 431062
Aligned: 21 rows
Threshold Bit Score: 189.752
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAL82739       19 IRKNFTYFKKSFFINIGFESIYKVLTSFIFLPFITMVLNYFMHLRGMKMMANNQILSFVGSIP-GILTILILGILSFLFI 97 
Q38Z34          8 LKANFQAFGRHWSVYVLLVVSINLVLTSLIVPGLTWGVNRLLVVNGIGYLTYTNFVSVLTKHPlVLISLVLLVLLICGLV 87  Lactobacillus ...
Q03U33          7 WRESTRHFFQHWGSYVTLVFITNLAISYVAVPAFTWLTAALMKWQHVPYVSYTNIGSIALRHPlAIIGLLLILLAIITLI 86  Lactobacillus ...
Q837Q4          7 FKNGTRQFFKDILQYLWLFFTLNVLL-LLVGGAFSWATSNALKTQGIPYLSFNNL-NLLLEKPlALVLLILLLLLFLGAV 84  Enterococcus f...
Q8CYV1          9 KKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLASFLLDQTGYLFISYNNVLAILTHSPlISLAFLALIVINLLVA 88  Streptococcus ...
bgi:05SSU0193   4 IQREFQKIYYNLDKILLLFFTLFTFMEFVWIPLNSWISEGLLAMTGHAYLSPTNLLSVFAENLlVTGLFILLFFVNIAIA 83 
Q8Y9B6          4 LKDSFKVLYQFKTDYLKVTLLLTILQAFVIGPFIYYFFFFILRVIGVPGITDANLGEVFS-SPvAIIMLLILALLILLFV 82  Listeria monoc...
Q186M2         17 LSKLVFIIKYNFSTLILFELFHKGLALFFIWPSIRYIFDILIKSLHIVYLNMDNFIKVLT-NPmSIVLIILSVIILAFYA 95  Clostridioides...
Q898L8         10 IINIFKDIKYGFFRLIKYQIGTKILLSIIILPIFNFLINILIHKSDRFPLVNGEIIKFGL-SKeGAITLFMLFILAYIII 88  Clostridium te...
Q81I31         13 MRHSFQTVKFAFWNVLTFQLAYKLLAAIVFVPLFGIIFNKLLYFGGYANATNDELLAFLK-TPyGILAIVILSLLALFLI 91  Bacillus cereu...
CAL82739       98 FIEYAGLIVISQETYFd---KKISAKAA-FFTAMKSIRGIMKVGSIPIIIYVLFIIPFVasSMGLSSSLLPKIEIPTFIM 173
Q38Z34         88 YIQMAFLFRQIKRIQEq---TPASQWQL-LKQSGHDLLTLKPLTMLIMIGYFLLILPFG--QIIFKSVLLNKVTIPAFII 161 Lactobacillus ...
Q03U33         87 YWQFAYLLLGIMNIRNg---RPQTSRAV-LGDVFRSLVGASPSTFLFFIGYFVVIIPFG--SELFSTPLLNKAKIPAFIV 160 Lactobacillus ...
Q837Q4         85 FYQFTFLLLGIFQIRQd---HRFHFKGV-TKASFKVLKKQGARSWLFFFGYFVVIVPFG--NLIFQSNLLTKFVIPDFIV 158 Enterococcus f...
Q8CYV1         89 YFQIGLLFIGARHLLYnekrRLIEYIRKvFHESFGFMKKLTCAKALFIFFYIAMLFPFI--RKMLKIYYLNKIVIPEFIQ 166 Streptococcus ...
bgi:05SSU0193  84 YLELALLFTGVWQLLDekvkHLTDYLRDvRDSMVAIIRHSSLPKVLFLLFYSVILLPFL--RRVLNIYYFNKIVVPQFIV 161
Q8Y9B6         83 YYELGFFIMMAIYQLRg---ESYTFFKI-IQRLNVKAKYFLSYQAIYFLLYFFLLLPIA--GLSLPITITENLYLPHFIT 156 Listeria monoc...
Q186M2         96 FFEFTSVIICLNKSIKy---EKIGLFEL-FKISFENSIKLLYPKNILLFIFVILIIPLV--NTVLISGFIGKIQIPEYIL 169 Clostridioides...
Q898L8         89 LSEIGGLIIISNQLYLr--kEESSYADI-FKYCFKRFYKIFGVGSIFILIQFFLFVPLL--DIGINSSFTSFVKIPDFIE 163 Clostridium te...
Q81I31         92 FTEFAVLIIISYFAHKr---QKVKLRPI-LYKTVTYLPTLFTYCLPGFILYAVVLLPLL--NMGYETALIPQIQIPNFIT 165 Bacillus cereu...
CAL82739      174 DvVYKTPKWI-SL-YAIVFFILFYFLIRWIFSLHVVVLEGK-DFSSALKRSSQLVKGSFLKIwTTMFLWNLSIFAIVAVV 250
Q38Z34        162 QdMWTTPKI--WGpIILVYTLALILSIRLITFLPETIFNKKlSTTRLLQKCWQTTRGRFWRL-LIKVGVLAIAITLVGVL 238 Lactobacillus ...
Q03U33        161 TyLMANPLW--AVfLGIFYVAAAYIGIRLIAVLPLMMLDGY-HSHEAIRLSWQRTRRHFWAY-FSKILVTLAIVTVMVTL 236 Lactobacillus ...
Q837Q4        159 E-FLSQRIPY-LVgLLAFGLLVWYLAIRFIYTLPLMILERK-KAGEAVKASWSMTNKRLWFI-IRNIAFVTIAVFVSTYV 234 Enterococcus f...
Q8CYV1        167 A-YLEDRYWMwWLsILLLSLIFLYVSVRLMFALPKIVYDQL-TVREAVMFSLEKTKKRVTFY-AWNLFYILLKAHLLFYL 243 Streptococcus ...
bgi:05SSU0193 162 D-YLSNTVWL-GIlILIFLLLFFWLAARFMYALPNIYFEHR-GVKESIAYSWEKTRGRKQIGsLFRLIWLVTFPVLLFTG 238
Q8Y9B6        157 DeLMKTTTGT-WL-YVIAIAIIFYISARLVFALPYFIEDKSlKISGAIRKSWKYPQKHLFFMlLKWVLIIVAIGFLVSII 234 Listeria monoc...
Q186M2        170 DyIKSDIILN-II-YMIFLLIIYISVIRWIFSIHEITLNTE-NFKRARKESVNLIKGKIIRTiIYSLILSLVVAIIGYAI 246 Clostridioides...
Q898L8        164 DyIYSDNILI--VfQYILMMIMIYFALRWIFSLHIIILENK-SATKALKESGQLVKRNLKEFiKRYVTFSILNGILYFII 240 Clostridium te...
Q81I31        166 GeLFKTTMGQ--VgYYTFFAVVAYLNLRWIFVLPIVVLEQK-PFRVAARKSATLVKESFFKVlFFLVGFFISIGIVYVVF 242 Bacillus cereu...
CAL82739      251 VILVGIGMV----LLNEVlKGNVK--LFVTILSFVttmggiLVMIATLFISPLTIMLITQLYYRQVKMKDGVEPIPmitt 324
Q38Z34        239 SQLLFFNLQr---YYDQN-LPHYA--LLLAILNLF------ILEIISQILLAMSIVMILQLILKQAGYLVPSETRVkv-- 304 Lactobacillus ...
Q03U33        237 IYGLIYLGQl---GFD---RTGFG--LAAATFNLF------LMEIITEFIVCYSTVIFMMVVLSSHDSQQQTPLSL---- 298 Lactobacillus ...
Q837Q4        235 IYVLLYLLQl---KLDTL-SDTIS--LLGGILNLT------VVQFLQFVSNAWLSVLLINFLYTQLNVQAE--------- 293 Enterococcus f...
Q8CYV1        244 PLIPLLLAQt---LVDDI-TQRES--LILGILNFV------VIKNLYYMALTYFLVKFVSFLTG---------------- 295 Streptococcus ...
bgi:05SSU0193 239 VGGLFYLVQl---LAEHF-VPSAS--YWLAVVCYA------LLKLAYYGVVALFMMGFVSLLTG---------------- 290
Q8Y9B6        235 ATIIMLPLL----LVEKI-TPGIA--VVIAGITLT------ILQVIGFFAAGIFQGIIAQLLVKNAFAIKEQPALVtrs- 300 Listeria monoc...
Q186M2        247 YHSGIIFIGiwtkYCTDMeFLKNV--FINRCIAFEey--frLILSIFIFILDIGFISATYYQYKGVNISKNN-------- 314 Clostridioides...
Q898L8        241 LVLWMSLVAn---ISKNIsYGSYSgkFILGGIVFFhqmgavLL---SFIYIPIQVQFTTRMYYKFAYINENKTIPSlnlk 314 Clostridium te...
Q81I31        243 LGMYLLCLWg---VYEFTnPKGTFalLAESTISVFlt---sTLYLFSFIVTPFYIMAITRLYLQKVPVEDVLLEEGldys 316 Bacillus cereu...
CAL82739      325 stpskinwqnlfnrHKKKLIAVSVLGIMIFTWLSYVYF 362
Q38Z34        305 ------------ilKQRSLRIRMRQGAAMLLLILVAAG 330 Lactobacillus sakei subsp. sakei 23K
Q03U33        299 --------------FSFREPARTKLRTRLLIISGLTLI 322 Lactobacillus brevis ATCC 367
Q837Q4        294 --------------TTTKVAFDKETKRNKLVTIGMGLG 317 Enterococcus faecalis
Q8CYV1        296 ----------------KELDMLPRREKDHIVRWGVMTC 317 Streptococcus pneumoniae R6
bgi:05SSU0193 291 ----------------KQLPIYRRKRLRHHLRLAILLV 312
Q8Y9B6        301 -----------qfpHKKRFIIVAIIIFIIFSSFNIYTV 327 Listeria monocytogenes
Q186M2        315 --------------IKKEKKSISKIVFNLVLILLISYI 338 Clostridioides difficile 630
Q898L8        315 ikek--dslldkifKNKKMFIEIFTIIFLFSTLLIGMI 350 Clostridium tetani
Q81I31        317 ktk----adkcffqKHRWKFIGVYIVGIITAGMVVAFI 350 Bacillus cereus ATCC 14579
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