Conserved Protein Domain Family
PDDEXK_2

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pfam12784: PDDEXK_2 
PD-(D/E)XK nuclease family transposase
Members of this family belong to the PD-(D/E)XK nuclease superfamily. These proteins are transposase proteins.
Statistics
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PSSM-Id: 432783
Aligned: 19 rows
Threshold Bit Score: 197.501
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q24RR6         15 KIDYAFKLIFGKE-G-NEAILIAFLNAALKlpQERRIEAITIMNPELNKEYQGDKKSILDVRAETSEGMQINIEIQLSNQ 92  Desulfitobacte...
WP_012508639    7 RVDFAFKKLFGSE-E-NKDLLISLINAIVS--EEDQVVEIELKNPYNLADYRAGKISILDIKAKAENGRWFNVEMQISED 82  Pelodictyon ph...
WP_015807586   26 FVDFSFKRLFATE-E-SKPILIGLLNHLFKg-RK-YITEIEYGKNEFPGEIAQEGGAVFDVYCTDVNGSKFIIEVQRGNQ 101 Pedobacter hep...
jgi:Amet_0743   9 MNDFVFKALFGREdAtSKQLLIELLNDTLRakGEDLIASVKYLNPFNYKEYEFDKLSVLDIKAETEKGERVNIEVQVKPE 88 
Q2FSM1         22 KNDYVFRYLLGEE-G-NEELLTSLISAILG----RRITHATIKNPYILKLYYDTKECILDIKAEIDENILVDIEMQLCNS 95  Methanospirill...
Q73QP0         10 RNDYAFKRVFGVE-E-NKDVLQDLLECILDi-QPEDIAGLELLDKEFHKDSISDKTGVLDVKLRLKNNTIIDIEIQNRWN 86  Treponema dent...
Q73N12         10 RNDYAFKRVFGVE-E-NKDVLQDLLECILDi-PPETIAGLELLDKEFHKELLSEKLGILDIKLRLKDGTFVDIEIQNSWH 86  Treponema dent...
Q73K05         12 RNDYAFKRIFGTE-E-NTDILQDLLECILDi-LPENIAGLELLDKEFHKEILTEKLGILDIKLRLKDKTIINIEIQNRWR 88  Treponema dent...
Q8XNB3          9 QIDFVFKKIFGTE-K-NKPILINFLNAVIK--PTTPIKDVEIKNNDIDKDFLEDKFSRLDVKATTSNKEHINIEIQVKNE 84  Clostridium pe...
Q24PT3          8 INDYLFKWVFGRP-E-NKEILLSFLNSVLSpnGQDELADITLAERELDPEHIHDKLSRLDILGKGNDGSIINIEVQIANQ 85  Desulfitobacte...
Q24RR6         93 YDMEKRSLYYWAEMYSRQIREGMAYK---ELAKAVTINILD-FNYLKQ-TSNYHNVFHLYEDEEKF--QLTDALEMHFME 165 Desulfitobacte...
WP_012508639   83 YNFDKRAIFYWAKLVTEQLSEGMMYK---ELKKTISINILD-YNFVPD-TTDVHSCYKIINTATGKddRLHDVFELHYIE 157 Pelodictyon ph...
WP_015807586  102 EYFKERALFYVSRAISEQAPKGDRKGwayKLTEVYLLAFLEdFNLPDSpKSEYVQDICLANRHTGI--IFYDKVGFIFIE 179 Pedobacter hep...
jgi:Amet_0743  89 VSYRKRSLYYWAKTYAETIGEAEPYE---ELKKTIVINIMD-YDAIHE-SKKLHTHFKLLEREEHF--TLTEDLQIHYLE 161
Q2FSM1         96 PELINRILLYWSRLYASQMKAGDGYH---VLKKTISILILDdDPYHTD---DFHVCSRIINCVQKF--ELTDLLEIHILE 167 Methanospirill...
Q73QP0         87 SEFVQRTIFYWAKMYTENLKTGEVYT---KLPKCITINIVG-EGFDLN--SLIHSEYNVVEKHLND--RLSDELEIHFLN 158 Treponema dent...
Q73N12         87 FDFPERTLYYWSKMYNENIKQGQDYT---KLPKCITINLIG-KDFDKN--KRLHNKYLVLEKDTKE--PLVSKLEIHILN 158 Treponema dent...
Q73K05         89 GDFPERSVYYWSKMYNESIKQGQDYT---NLPKCITINLIG-KGFNKN--KRLHNKYFVMEKDTKE--PLFSKLEIHIIN 160 Treponema dent...
Q8XNB3         85 YNMIQRTLYYWSKMYSEQIQNRDNYS---KLERTVCINILN-FKYLKN--DKYHNAYRLKEITSNE--ELTDLQEIHFIE 156 Clostridium pe...
Q24PT3         86 YDIDKRTLYYWAKLYQGQLQKGQRYK---DLSRTITVNVLN-FGFLPD-SQKYHSMFSLYEAHSGY--RLNRDLEIHFLE 158 Desulfitobacte...
Q24RR6        166 LPKLLAKWRNREISpwe-neLVRWLLLLEGADNQEILQTLEeiamKDPVLHQAMTAWEETsDDPRIREAYFDRRKAVLDE 244 Desulfitobacte...
WP_012508639  158 LKKFNKLHHEISST------LDRWTTFLTTAHQLDREHTPKel-aVDKNIVKAIAAIDRM-FNEEERQVYEVRKQSLVDA 229 Pelodictyon ph...
WP_015807586  180 MLNFVKGSDELYTE------LDKWLYALKHLTEFKQRPEYL----SGPEFDQLFTLANYAsLTPEERDMYNSSLKRKWDN 249 Pedobacter hep...
jgi:Amet_0743 162 VPKLAEAKQIEALEg-----IELWIAFLKEAGKAGNEEKIErlkrRSESMSKVIESLETVsADEKLLEAYRAREKARRDE 236
Q2FSM1        168 LPKVHKRREQDTNDk-----LIPWMNFLYAQTREELDMASE----ANPVIRKATDMLTAMsRDEEERLRYEAREEFLFDQ 238 Methanospirill...
Q73QP0        159 LAKVKEQDENIESDekk-kkLYNWLKFIETDDEEVRNMLAQ----ESPMMRKANSTIELMeMSPKEKWLYENRMKYEHDK 233 Treponema dent...
Q73N12        159 LEKAKLLKEAQCKDnkt-krLLNWLKFIETDDREVREMLEQ----ESPMMAKANTAISVMeMSSKDKWLYDSRMKYEHDR 233 Treponema dent...
Q73K05        161 LETAKLLEESNYTDikt-krLLSWLKFIETDDREVRKMLAQ----NSKTMKKANAAIEVMeMSPRDKWLYESRMKYQHDM 235 Treponema dent...
Q8XNB3        157 LPKFNEIGNKENVDvekmdaLEKWLEFLVEPESNTVRQLEL----SNEEIKLAKSELYRLsMDSKEREQYNMREKAIYDR 232 Clostridium pe...
Q24PT3        159 LSKWKALSVKPKTR------LDKWLMYLSNTNPQEMEEIAM----SEPAIRKALTAEEIFlKQDKERYLYEMREKALLDH 228 Desulfitobacte...
Q24RR6        245 KAAIREA 251 Desulfitobacterium hafniense Y51
WP_012508639  230 ESKIASA 236 Pelodictyon phaeoclathratiforme
WP_015807586  250 KNVLDYA 256 Pedobacter heparinus
jgi:Amet_0743 237 ISKLAYA 243
Q2FSM1        239 QYGLQAA 245 Methanospirillum hungatei JF-1
Q73QP0        234 ASWKHVG 240 Treponema denticola
Q73N12        234 ASCISEG 240 Treponema denticola
Q73K05        236 ASEKHEG 242 Treponema denticola
Q8XNB3        233 ISALESs 239 Clostridium perfringens
Q24PT3        229 VSAIEGA 235 Desulfitobacterium hafniense Y51
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