1HRP,1XWD,1FL7,1HCN


Conserved Protein Domain Family
GHB_like
?
cd00069: GHB_like 
Click on image for an interactive view with Cn3D
Glycoprotein hormone beta chain homologues
This family of cystine-knot hormones includes the beta chains of gonadotropins, thyrotropins, follitropins, choriogonadotropins and more. The members are reproductive hormones that consist of two glycosylated chains (alpha and beta), which form a tightly bound dimer.
Links
?
Statistics
?
PSSM-Id: 200450
Aligned: 143 rows
Threshold Bit Score: 64.6109
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
Conserved site includes 7 residues -Click on image for an interactive view with Cn3D
Feature 1:receptor binding site [polypeptide binding site]
Evidence:
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                                             #                                          
1HRP_B         9 CRPINATLAVEkegCpvCITVNTTICAGYCPTMTRVLQgvl-paLPQVVCNYrdVRFESIRLPGCprgvnPVVSYAVALS 87  human
1XWD_B         3 CELTNITIAIEkeeCrfCISINTTWCAGYCYTRDLVYKdpa-rpKIQKTCTFkeLVYETVRVPGCahhadSLYTYPVATQ 81  human
XP_002939523  32 CAVREFTFLAKkpgCk-GLRVTTDACWGRCETWEKPVLdppyieAHHRVCTYneTKLVTVKLPNCspdidPFFTYPVAVR 110 western clawed ...
XP_001511472 226 CAVREFTFLARkpgCr-SLRVTTDACWGRCETWEMPILdppyieAHHRVCTYneTKQATVKLPGCapgvdPFYTYPVAVR 304 platypus
NP_001007014  35 CAVREFTFVAKkpgCr-GLRITTDACWGRCETWEKPILeppyieAYHRVCTYneTRQVTVKLPNCapgvdPFYTYPMAVR 113 Norway rat
XP_003267836  37 CAVREFTFLAKkpgCr-GLRITTDACWGRCETWEKPILeppyieAHHRVCTYneTKQVTIKMPNCapgvdPFYXYPVAIR 115 White-cheeked G...
XP_003214333  42 CAVREFTFLAKkpgCk-GMRITTDACWGRCETWEKPVLdppyveAHHRVCTYneTKLVTVKLPNCaanvsPFYTYPKAIR 120 green anole
XP_003206828  35 CAVREFTFLAKkpgCk-ALRITTDACWGRCETWERPILqppyieSYHRVCTYneTKLVTVMLPKCapgvdPFYTYPVAIR 113 turkey
CAG05739      30 CAVREFSFVAHkpgCr-GLRVTTEACWGRCHTWEKPVPdppyihRHHRVCTYsqMRHVTVRLPGCqpnvsALYHYPVAVQ 108 spotted green p...
CAR95358      79 CAVREFTFVARkpgCr-GARVTTDACWGRCQTWEKPTLepphveAHHRVCSYneTRAGSVRLPGCaphvdPVFSFPVALS 157 sea lamprey

Feature 1               ##  # ###
1HRP_B        88 CQCALCRRStTDCGGP 103 human
1XWD_B        82 CHCGKCDSDsTDCTVR 97  human
XP_002939523 111 CDCDICSTStTECVTF 126 western clawed frog
XP_001511472 305 CDCGPCSTAtTECETP 320 platypus
NP_001007014 114 CDCGACSTAtTECETI 129 Norway rat
XP_003267836 116 CDCGXCSTVtTECETI 131 White-cheeked Gibbon
XP_003214333 121 CDCSMCLTTtTECETF 136 green anole
XP_003206828 114 CNCDFCSTAtTECETA 129 turkey
CAG05739     109 CRCAVCSTQdTECETF 124 spotted green pufferfish
CAR95358     158 CVCKMCSTDdTECETY 173 sea lamprey

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap