Conserved Protein Domain Family
PRK09418

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PRK09418: PRK09418 
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
Statistics
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PSSM-Id: 236504
Aligned: 19 rows
Threshold Bit Score: 1469.17
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
225866109   7 MLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV 86 
47529642    1 MLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV 80 
42783240    1 MLAGATLAIGVIAPQVLPATAHADEQTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV 80 
218231424   7 MLAGATLAIGVIAPQVMPTTAHADENTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV 86 
296504618   7 MLAGATLAIGVIAPQVMPATAHADENTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEVKNSV 86 
218899286   7 MLAGATLAIGVIAPQVMPATAHADENTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEVKNSV 86 
163941865   7 MLAGATLAIGVIAPQVLPTTAHADENTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV 86 
222097573   1 MLAGATLAIGVIAPQVLPATAHADEQTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV 80 
301055621   7 MLAGATLAIGVIAPQVLPTTAHADEKAGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEGKNSV 86 
217961617   7 MLAGATLAIGVIAPQVLPATAHADEQTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKAREEAKNSV 86 
225866109  87 LFDDGDALQGTPLGDYVANKI--NDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNV 164
47529642   81 LFDDGDALQGTPLGDYVANKI--NDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNV 158
42783240   81 LFDDGDALQGTPLGDYVANKI--NDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNV 158
218231424  87 LFDDGDALQGTPLGDYVANKI--KDPKNPVDPSYTHPLYRVMNLMKYDVISLGNHEFNYGLDYLNKVIEKTDFPVINSNV 164
296504618  87 LFDDGDALQGTPLGDYVANKIkdKDPKNPVDPNYVHPLYRVMNLMKYDVISLGNHEFNYGLDYLKEVTSKTKIPVINSNV 166
218899286  87 LFDDGDALQGTPLGDYVANKI--KDPKNRVDPSYTHPLYRVMNLMKYDVISLGNHEFNYGLDYLKKVTSKTKIPVINSNV 164
163941865  87 LFDDGDALQGTPLGDYVANKI--NDPKKPVDPSYTHPLYRVMNLMKYDVISLGNHEFNYGLDYLNKVIEKTKFPVINSNV 164
222097573  81 LFDDGDALQGTPLGDYVANKI--NDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNV 158
301055621  87 LFDDGDALQGTPLGDYVANKI--NDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNV 164
217961617  87 LFDDGDALQGTPLGDYVANKI--NDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNV 164
225866109 165 YKDDKDNNEENDQNYF-KPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAE 243
47529642  159 YKDDKDNNEENDQNYF-KPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAE 237
42783240  159 YKDDKDNNEENDQNYF-KPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAE 237
218231424 165 YKDDHDDKEENDENYF-KPYHILKKEVVDEAGQKQIVKIGVMGFVPPQIMNWDKANLEGKVKAKDIVATARIMVKKMQDE 243
296504618 167 YIDDHDGNDENDEHYFdRPYHILEKEVVDEAGQKQIVKIGVMGFVPPQIMNWDKANLEGQVKAKDIVETAKKMVPKMKAE 246
218899286 165 YRDDHDGNDENDEHYFdRPYHILEKEVVDEAGQKQIVKIGVMGFVPPQIMNWDKANLEGQVKAKDIVETAKKMVPKMKAE 244
163941865 165 YKVDHDDKEENDENYF-KPYHILKKEVVDEAGQKQIVKIGVMGFVPPQIMNWDKANLEGKVKAKDIVATAKIMVKKMQDE 243
222097573 159 YKDDKDNNEENDQNYF-KPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAE 237
301055621 165 YKDDKDNNEENDQNYF-KPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAE 243
217961617 165 YKDDKDNNEENDQNYF-KPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKMKAE 243
225866109 244 GADVIVALAHSGVDKSGYNVG--MENASYYL-TEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 320
47529642  238 GADVIVALAHSGVDKSGYNVG--MENASYYL-TEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 314
42783240  238 GADVIVALAHSGVDKSGYNVG--MENASYYL-TEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 314
218231424 244 GADIIVALAHSGVDKSEYKEAnkMENASYHLaTQVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 323
296504618 247 GADVIVALAHSGVDKSGYNVG--MENASYYL-TEVPDVDAVLMGHSHTEVQDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 323
218899286 245 GADVIVALAHSGVDKSGYNVG--MENASYYL-TEVPGVNAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 321
163941865 244 GVDIIIALAHSGVDKSEYKEAnkMENASYHLaTKVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 323
222097573 238 GADVIVALAHSGVDKSGYNVG--MENASYYL-TEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 314
301055621 244 GADVIVALAHSGVDKSGYNVG--MENASYYL-TEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 320
217961617 244 GADVIVALAHSGVDKSGYNVG--MENASYYL-TEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN 320
225866109 321 GKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW 400
47529642  315 GKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW 394
42783240  315 GKWEVQKEQSKPQLRPIADSKGNPLVQSDQHLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW 394
218231424 324 GKWEVQKDQSKPQLRPIANSKGTPLVESDQKLVNEIKDEHQATIDYVNTPVGETKAPINSYFSLVQDDPSVQIVTNAQKW 403
296504618 324 GKWEVQKDQSKPQLRPIANSKGTPLVESDQKLVNEIKDEHEKTIEYVNTHVGETKAPINSYFSLVQDDPSVQIVTNAQKW 403
218899286 322 GKWEVQKDQSKPQLRPIADSKGNPLVESDQKLVNEIKDEHEKTIEYVNTHVGETKAPINSYFSLVQDDPSVQIVTNAQKW 401
163941865 324 GKWEVQKEQSKPQLRPIADSKGNPLVQSDQRLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW 403
222097573 315 GKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW 394
301055621 321 GKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW 400
217961617 321 GKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW 400
225866109 401 YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 480
47529642  395 YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 474
42783240  395 YVEEEF-KKPEYEKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 473
218231424 404 YVEQEL-KKPEYEKIKDIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 482
296504618 404 YVEQEL-KKPEYEKIKDIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 482
218899286 402 YVEQEL-KKPEYEKIKDIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 480
163941865 404 YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 483
222097573 395 YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 474
301055621 401 YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 480
217961617 401 YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG 480
225866109 481 QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNY 560
47529642  475 QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNY 554
42783240  474 QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIVNMTYEGKPVADNQEFIVATNNY 553
218231424 483 QFNQIDPTKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANANRIVNMTYEGKPVADNQEFIVATNNY 562
296504618 483 QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANANRIVNMTYEGKPVADKQEFIVATNNY 562
218899286 481 QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANANRIVNMTYEGKLVADKQEFIVATNNY 560
163941865 484 QFNQIDSKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGNVVNANTNRIINMTYEGKPVADNQEFIVATNNY 563
222097573 475 QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVINANTNRIINMTYEGKPVADNQEFIVATNNY 554
301055621 481 QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNY 560
217961617 481 QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVINANTNRIINMTYEGKPVADNQEFIVATNNY 560
225866109 561 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGP 640
47529642  555 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGP 634
42783240  554 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWTFKPIVADKLHTTFDSSPNAQKYIKKDGKISYVGP 633
218231424 563 RGSSKTFPGVSEGEVIYQSQDETRQIIVKYMQETPVINPTADKNWTFKPIVADKLITTFDSSPNAQNYIKKDGKISYVGP 642
296504618 563 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQKIKDIDPAADQNWTFKPIVADKLNTTFDSSPNAQKYIKKDGKISYVGP 642
218899286 561 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQKIKDIDPAADQNWTFKPIVADKLNTTFDSSPNAQKYIKKDGKISYVGP 640
163941865 564 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADQNWTFKPIVADKLNTTFDSSPNAQNHIKKDGKISYVGP 643
222097573 555 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLHTTFDSSPNAQKYIKKDGNISYVGP 634
301055621 561 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGP 640
217961617 561 RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLHTTFDSSPNAQKYIKKDGNISYVGP 640
225866109 641 SENEFAKYAIDITKKNDDDKETGgenpttpptgegdngenpttpptgegdnGENPTTPPTGEGDN--------GENPTTP 712
47529642  635 SENEFAKYAIDITKKNDDDKETG----------------------------GENPTIPPTGEGDN--------GENPTTP 678
42783240  634 SENEFAKYAIDITKKNDDDKETG----------------------------GENPTTPPTGEGNN--------GENPTTP 677
218231424 643 SENEFAKYAIDITKKN-DDKETG----------------------------GENPTTPPTGGGENpttpptggGENPTTP 693
296504618 643 SENEFAKYAIDITKKN-DDKETG----------------------------EGNPTTPPTG---G--------GENPTTP 682
218899286 641 SENEFAKYAIDITKKN-DDKETG----------------------------EGNPTTPPTG---N--------GENP--- 677
163941865 644 SENEFAKYAIDITKKN-DDKETG----------------------------GENPTTPPTGEGNN--------GENPTTP 686
222097573 635 SENEFAKYAIDITKKNDDDKETGgenpttp--------------ptsegnnGENPTTPPTSEGNN--------GENPTTP 692
301055621 641 SENEFAKYAIDITKKNDDDKETGgenpttpptgegdngenpttpptgegdnGENPTTPPTGEGNN--------GENPTTP 712
217961617 641 SENEFAKYAIDITKKNDDDKETGgenpttp--------------ptsegnnGENPTTPPTSEGNN--------GENPTTP 698
225866109 713 PTGEGDNGENPTTPPTGEGNNGGNPTTPSTDE----------GNNAGSGQTTTDNQNSKE-TTTVSENKE----ERDLPK 777
47529642  679 PTGEGNNGENPTTPPTGEGNNGGNPTTPSTDE----------GNNAGSGQTTTDNQNSKE-TTTVSENKE----ERDLPK 743
42783240  678 PTSEGNNGENPTTPPTGEGNNGENPTTPPTDE----------GNNTGSGQTTTDNQNAKE-TTTVSEKKE----ERDLPK 742
218231424 694 PTG---NGENP-TPPTEEGNNGNEPKQD--------------GNNTGSGQTTTDDQNTKEtTTTVSENKEaekdERDLPK 755
296504618 683 PKGDG---ENPTTPPTEEGNNGNEPKQD--------------GNNTGSGQTTTDDQNTKE-TTTVSENKEaekdERDLPK 744
218899286 678 ------------TPPTEEGNNGNEPKQD--------------GNNTGSGQTTTDDQNTKEtTTTVSENKEaekdERDLPK 731
163941865 687 PTGEGNNGGNPTTPPTGEGNNGGNPTTPPTDEgntvneskqdGNNAGSGQTTTDNQNEKE-TTKVSEGKE----ERDLPK 761
222097573 693 PTGEGNNGENPTTPPTGEGNNGENPTTPPTGE----------GNNTGSGQTTTDNQNVKE-TTTVSEKKE----ERDLPK 757
301055621 713 PTGEGNNGENPTTPPTGEGNNGGNPTTPSTDE----------GNNAGSGQTTTDNQNSKE-TTTVSENKE----ERDLPK 777
217961617 699 PTGEGNNGENPTTPPTGEGNNGENPTTPPTGE----------GNNTGSGQTTTDNQNVKE-TTTVSEKKE----ERDLPK 763
225866109 778 TGTNVASTIGAGLAFIGAGFLLLFRRKKANR 808
47529642  744 TGTNVASTIGAGLAFIGAGFLLLFRRKKANR 774
42783240  743 TGTSVVSTIGAGLAFVGAGFLLLFRRKKANR 773
218231424 756 TGASIASTIGAGLAFVGAGLLMLFRRKKANR 786
296504618 745 TGASIASTIGAGLAFVGAGLLLLFRRKKANR 775
218899286 732 TGASIASTIGAGLAFVGAGLLMLFRKKKANR 762
163941865 762 TGTSVASTIGAGLAFVGAGLLMLFRRKKANR 792
222097573 758 TGTSVVSTIGAGLAFVGAGFLLLFRRKKANR 788
301055621 778 TGTSVASTIGAGLAFIGAGFLLLFRRKKANR 808
217961617 764 TGTSVVSTIGAGLAFVGAGFLLLFRRKKANR 794
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