Conserved Protein Domain Family
DUF4763

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pfam15960: DUF4763 
Domain of unknown function (DUF4763)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 237 and 332 amino acids in length. There are two completely conserved residues (C and R) that may be functionally important.
Statistics
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PSSM-Id: 406386
Aligned: 21 rows
Threshold Bit Score: 189.095
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002000506         14 CRAPGLPNCEPedthisvveqvsfrkie----------------ppippktlhcdsidrvDELEDADVEGEEEEEQEASA 77 
EDV92017             91 CLIRRIQQMQLiikqr----------------------------------------kqdqQQLDTTEVSTEQQEEEEVIK 130
WGS:AANI:GJ15807-PA  88 CLIRRIEQMQLvikqr----------------------------------------keaqMELDISDYSTEQEPETSAT- 126
XP_001957816          3 CRAPGLLT----------------------------------------------------SGSE-----LNISDLDGLEN 25 
Q9VT87                3 CKAPGLLE----------------------------------------------------TPSESELTHCSISALDNIPI 30  fruit fly
WGS:AANI:GJ11073-PA  12 CKAPGLPICELedsssnvevvdnls-----------------------------igqpepgrtllcdcVKKASEEEEPSL 62 
XP_001994541         10 CRAAGLPLCEPesstsvdevhpfrk-----------------------ilspqpaktllcdcVFGDDGDDDEGGESELSL 66 
WGS:AAQB:GK11525-PA  42 CKAKGIPICEPekeevadvkvisty---------------------felprvkkaklfqcPQSDSIELIEAISEESEIPA 100
EDW34093             39 CNAPGLMRCVPkvevppaetlwkfiappwvpktklfhceppppptptptpgrsrrkgsqiSQVSQMDVEEEQSSDQSSPP 118
Q9VI34               16 CKAAGISKMENtkpndkklaqskfafk------------------hngpkkvfhctmqsvLQSEDCWIAEEVLEES---- 73  fruit fly
XP_002000506         78 SQSTKPEELVELEQIEAELLEqKNAVDLIGEEIAldmpe--cpsdDSCVNMELELQRGK-VHPHIYKLQQENHLLRQQLS 154
EDV92017            131 QPPIPQLGKFLFQECMEQTLE-ETKLDILKRELK-----------AEMKPDSKFNSLSCdEQLEIRDLRHAHHRLQCEID 198
WGS:AANI:GJ15807-PA 127 --PIPELGVFEFKQCRVKSAKiKKDSSPDQEKLAd---------kELPLPDAQKDPLNCeEQLEVRNLQHAHHQLQCEID 195
XP_001957816         26 QYAEESNNEVDLDEEYDKLEKlKQRVLHLRGLVAgp--------lQPHEELHGLSLDGVsKNPELQKAQVKTMRAKARVA 97 
Q9VT87               31 QEE-ECPSELELSKTFDKLERmRERVLYLKSLLIhpvqvnkvecpPESDQMRLDIEQSSsDNDELRVVQQDTVRALQQII 109 fruit fly
WGS:AANI:GJ11073-PA  63 EQSTTVDEELQLEDIQDELEKnRALVDLIGQRLSlnipd--cpelDACMDMQVELNKDG-MHPEILKLHRNNSQLRQQLS 139
XP_001994541         67 EQPLTEGDDLQLEDIQDELDKkKAFVDLIGKRLSlqvpd--cpigDVCVDKQLELNNFD-THPEILELQRNNHKLSLQIR 143
WGS:AAQB:GK11525-PA 101 ----TLDEELQIDDIQNEVDRmKLKVSQINLLLGlntpe--cpsiDPCLDVDTELKKHL-ISPEILNLQRNNQKLQQQIS 173
EDW34093            119 ----TMVEEMQLEEILAEVKRiKERVGEVDRQLGtripe--cpdiDPCVDMDVELLAFN-TSPDILELQRNSHKLRQQLA 191
Q9VI34               74 ----NEKSNLELEDIYDEVFRlKRRVNRLNYQLGtnipe--cpkiDPCLDDHIFLTNVKeVHPEILQLKFASHKLQHQLT 147 fruit fly
XP_002000506        155 KAQLSCKAIDLSLKYLRNSLCRDLKAGAILRRRLDELNSFKLNVEHEQVLCRQRYNHLQEVKYDWVDCK-AYLKESAEYT 233
EDV92017            199 EMVCNACTMRELLLKIRNQVGQDKKRLLKLAAIATKHHEWSNLIYKELPVCKQRYQYLLEKKLSKSEAH-RLIHAHMVKV 277
WGS:AANI:GJ15807-PA 196 ELICNYRLMRGLLNKMRNQLCQENRRVRKLGSITHQYQDWSRLVAEELPVCKQRYNQLIEIKLSKAEAN-RVISAHKAKA 274
XP_001957816         98 KLSWRLKGDRKILRRFNAELLCHLQCSGKLLEKMGEPMKWRPQHEHYKELCRERYSQLDISLCNYLGYS-DRMRPIQTKL 176
Q9VT87              110 DVNRQLKETTDSLTGLDEKARKNIRCIRKLSKRLLEVPKWKEELKHNTGLCLERYNDLDISRGNYLDYSdNFVRPIQTNM 189 fruit fly
WGS:AANI:GJ11073-PA 140 QLQHSCKAVDLSLKYMHNSLCRDLEAGAAMQRRLNELDSFKRIAEHEHALCRQRYRHLEQDKFDWNDCF-AYISKHYMEL 218
XP_001994541        144 ALQHSCTATDASLKHLRMLLDRELEAAVVLQRRLDRLDSVRRTMEHEQALCRQRYRHLQEDKYEWQDCH-AYIKRSREEA 222
WGS:AAQB:GK11525-PA 174 QLQLCRKASDLSMNNLTESISADRAAAGNLKKRLGELDSLKRTLEHEQALCGQRYRYMEKDKYDGSDLH-PLFASANVNI 252
EDW34093            192 ELQLCRVATDSNVKAIRESICREMENANRLQKLLNELDSFKRKLEREQALCRQRFRYVEQVKVDGAECN-NYFSSERKLM 270
Q9VI34              148 QMQSVRRSSNLAKKLVRDEYCRSKKLGDQLQIEIQKLDSFKLKFEKHQGLCLQRFRFLDQDKYTGREFY-EFIEKSNEMI 226 fruit fly
XP_002000506        234 QREIKKIVRRADYTQPHLDALKLLKGAKRMAMDLHFDLTNRMTRLGQR 281
EDV92017            278 IHYNKKFLTRRELRYELREFHLEIDELEKYVNDLRQDMVRRFSSIENE 325
WGS:AANI:GJ15807-PA 275 MRYSNTFLTSRQLRYELREFHSEIEELKEYASDLRKEMIRRFSSIEHE 322
XP_001957816        177 FRAFHVKIPMFYYRRDFRNISMSLGRIQSTIRFCAKRLMAHIREVEED 224
Q9VT87              190 KFCFASKAPLICNKQDYNDLVSALSKSRKTLLKCHGELLKYTQKVDEA 237 fruit fly
WGS:AANI:GJ11073-PA 219 QPLLKKYVRRTEYGQLRQDASELLNQAKLEAKELHDYLAENMNTLSQR 266
XP_001994541        223 SLELVKFVPRLEYIQPKHDAVQLLNQTKRLGKELHEFLVENMARLSLR 270
WGS:AAQB:GK11525-PA 253 KRVISKLVPTREYEKQKVQEIKKIQYLNEQCRKLFDYMLESFDKLDAK 300
EDW34093            271 EYFVGKLVTKADYQQQKRRALKEIDFLKLKAKKFHDHLFYATDKLDav 318
Q9VI34              227 TTQLKKQMLKSEYKPFRKEAARVTISLKTAAENLQDYLSSVINNKKCE 274 fruit fly
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