Conserved Protein Domain Family
Rad9

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pfam04139: Rad9 
Rad9
Rad9 is required for transient cell-cycle arrests and transcriptional induction of DNA repair in response to DNA damage. It contains a Bcl-2 homology domain 3 (BH3).
Statistics
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PSSM-Id: 427739
Aligned: 8 rows
Threshold Bit Score: 302.363
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P26306        13 LARIFTNLSRIDDAVNWEINKNQIEITCLNSSRSGFSMVTLKKAFFDKYifqpdsvllTGLMTPTIRIRTQVKPILSVFr 92  Schizosaccharom...
Q5KH95        14 FVRLLQCASKFGDDLHICIGEGLWEMSAVDSSKSAFCLFKLNKDFFYKW---------EKRVSGQIICRILVKSVIAVL- 83  Cryptococcus ne...
XP_013021985  13 LSRIFLNLSRIDDAVNWEINKDQLILTSLNSSRSGFGMVTLTKKFFDKFtfhpdtlflTGFVSPTVRLSTQIKPILSIFr 92 
Q869Q1        13 FSKSLQCISRIGDDLYIEGRQEYIKFTTVNNSKSAFVVFQFSNSFFHSY---------SLEGDEGIQYKAKSKLCFQMFh 83  Dictyostelium d...
Q5E9X8        32 FGKAIQALSRVSDELWLDPSEKGLALRSVNSCRSAYGCVLFSPVFFQHYqwsasvkmnDTDIILNLNCRLGMKSILPIFr 111 domestic cattle
Q6WBX7        14 FGKAVQTLSRVSDELWLDPSEKGLALRSVNSCHSTYGYVLFSSMFFQHYqwspfatmsDTDLPLNLNCKLAIKSVLPIFr 93  house mouse
Q7QCA1         2 LARAVNCFSKIGNELYFEATPDGLDLKTINSTNTAYAVVQFRRDFFISFqq------gSSDTPDENCCKISVKPILKIFk 75  Anopheles gambi...
Q058K5        13 LSRSIICLARVGNELVVQASPTQLALHTLNASRSAYQCITFQSSFFDVY----------TVSGPQAHFSVLLKAVCSVLr 82  thale cress
P26306        93 nkifdfiptvvttnskngygseSASRKDVIVENVQISIs---TGSECR-------------------------------- 137 Schizosaccharom...
Q5KH95        84 ----------------------GKSAQMSTVQRIDLRIidpsDELKSRlrrrrrggreangeeqkvfvddgpaypdddea 141 Cryptococcus ne...
XP_013021985  93 nkifessllvtnnpnantgatdSTSKKNVVVENVQIQIt---SGKECR-------------------------------- 137
Q869Q1        84 ----------------------SLS----NIDKCAMKI-----DLEGK-------------------------------- 100 Dictyostelium d...
Q5E9X8       112 ----------------------CLNSLEKNVEKCKIFT----RSDKCK-------------------------------- 133 domestic cattle
Q6WBX7        94 ----------------------CLNYLERSVEKCTVVA----RADKCR-------------------------------- 115 house mouse
Q7QCA1        76 ----------------------SLA----TIQTCKIWL----EVNQSK-------------------------------- 93  Anopheles gambi...
Q058K5        83 -------------------------TPLASIDHMSVQLp---DHDASK-------------------------------- 102 thale cress
P26306       138 -------IIFKFLCKHGVIKTYKISYEQTQTL-HAVFDKSLSHNNFQINSKILKDLTEHFGQRTEELTI----------- 198 Schizosaccharom...
Q5KH95       142 vggieakLIMRLVCDHGVIRKHSLHLGTSEFN-RADVDPETTPSGFTISSRTLRDWLDHFSISMPTSGSnasggl---sq 217 Cryptococcus ne...
XP_013021985 138 -------VIFKFYCKHGVIKTYKIAYEQTQML-HAVFDKASCHNNWQINSKILKDLVEHFGQKTEELTI----------- 198
Q869Q1       101 -------ISFYLLCKNGIQKTYSINYELSQLQ-SAVYNKNS-PYKISVKPKQISDCLNYFASNTEEISI----------- 160 Dictyostelium d...
Q5E9X8       134 -------VVIQFFCRHGIKKIHNVCFQGSRPL-QVIFQKNMCANTLVIQPRVLAEAIVLFTSSQEEVTL----------- 194 domestic cattle
Q6WBX7       116 -------VVIQFFGKHGIKRTHNVYFQDSQPL-KIIFEKSLCANILMIKPRLLTEAIALLTSNQEEVTF----------- 176 house mouse
Q7QCA1        94 -------IIFQFRCKSDVLKTHKIFLLESEHInSLNL-SQTFPSEIVGNHKVFSNILVHLYHSVDEISF----------- 154 Anopheles gambi...
Q058K5       103 -------VKWTLQCYSGMKKTYWITCNVEPDIqHLSLDRGRFPSTLVMHPRNLSKLLGNFQSSLQEITIiatdqtsfpsd 175 thale cress
P26306       199 ---QPLQERVLLTSFTEEVVHNrdilkQPTQTTVSIDG-KEFERVALNEG-----------------VSVTLSLREFRAA 257 Schizosaccharom...
Q5KH95       218 lgwMFAKDHVKIKSWEGPGNGN-----AGLSTEITIDT-EEFEDYGLIETrylddeatqqggnlgprVDLTLPMKEFKAT 291 Cryptococcus ne...
XP_013021985 199 ---QPVHGRVLLTSFTEEVIHNkdvlkQPTQTTVSIDG-KEFEQVSLNEG-----------------IVITLSLKEFRAA 257
Q869Q1       161 ---NLQRDRLLIKSSTDDKRGL-----KNLFTELVLDR-SDFDEYDFNGDg----------------EEISFNFKDLKTI 215 Dictyostelium d...
Q5E9X8       195 ---AVTPLKVCIKSSNEESMDLt----DSVYSEMFVGP-DEFDFFQIGID-----------------TEITFCFKELKGV 249 domestic cattle
Q6WBX7       177 ---SVTPGNFCLKSLSGELLDLt----SSVYSEMSFGP-EEFDFFQVGLD-----------------TEITFCFKELKGI 231 house mouse
Q7QCA1       155 ---DLNEEKTIVSNYVDNEQADr----STLRSTLSIDS-SAFQAYQLAGK-----------------ANLIFCYKEFKAI 209 Anopheles gambi...
Q058K5       176 aasEIGGKAVEFRSYVDPTKDGd----SLLHTQLWIDPsEEFLQYTHAGDp----------------VDITFSLKELKAF 235 thale cress
P26306       258 VILAEALGSSICAYYGVPGKPILLTFAk----gKNSEIEAQFILATV 300 Schizosaccharomyces pombe 972h-
Q5KH95       292 LVLAEQLSINLNMAFSEAGQPLTITNLe----nELEYIELFCAIATR 334 Cryptococcus neoformans
XP_013021985 258 VLLAESLGTSIASYYSVPGKPALFTFNk----gKFMEVEAQFILATV 300
Q869Q1       216 MAYVDVINNPCTWFIERAGLPFHINLK------YSSTYEVDFVLATL 256 Dictyostelium discoideum
Q5E9X8       250 LTFSEAIHAPIAIHFDFPGKPMALSID------D-MLLEANFILATL 289 domestic cattle
Q6WBX7       232 LTFSEVMHAPLAIYFDFPGKPVVLSVE------D-MLLEANFILATL 271 house mouse
Q7QCA1       210 TMFASLNKLNVRMSFSAPGSPLMLEMS------KGEVVHAKFIMGTM 250 Anopheles gambiae str. PEST
Q058K5       236 LAFCEGCEADIHLFFEKAGEPILMAPKfglgdgSSSSFDATLVLATM 282 thale cress
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