Conserved Protein Domain Family
SRP54_euk
?
TIGR01425: SRP54_euk 
signal recognition particle protein SRP54
This model represents examples from the eukaryotic cytosol of the signal recognition particle protein component, SRP54. This GTP-binding protein is a component of the eukaryotic signal recognition particle, along with several other protein subunits and a 7S RNA. Some species, including Arabidopsis, have several closely related forms. The extreme C-terminal region is glycine-rich and lower in complexity, poorly conserved between species, and excluded from this model.
Links
?
Statistics
?
PSSM-Id: 273615
Aligned: 4 rows
Threshold Bit Score: 728.94
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Download Cn3D
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
P49969     2 VLAQLGGSISRALAQMSNatvIdEKVLGECLNEISRALLQSDVQFKMVRDMQTNIRK---IVNLETLAAGTNKRRIIQQA 78  Hordeum vulgare
O42816     2 VLADLGSRLRGALSSVES---GsDDEIQQMIKDICSALLESDVNVKLVAKLRGNIKNkidESNVSKETSAMNKRKKLQKI 78  Candida albicans
O15821     2 VLSQLGSSLVTALRKMTSstvVdEEVINTLLKEIETSLLGEDVNPIFIRQMVNNIKK---KINSEDIPDGIDKRKLIKDS 78  Entamoeba histolytica
CAA34386   2 VLADLGRKITSALRSLSNatiInEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKS---AIDLEEMASGLNKRKMIQHA 78  house mouse

P49969    79 VFTELCNMLDPGKPA-----------------FTPKKGKPSVVMFVGLQGSGKTTTCTKYAYYHQRKGFKPSLVCADTFR 141 Hordeum vulgare
O42816    79 IFDELCALVDSNVEPpkpkklststktingkkVRLSKESSHVIMFVGLQGAGKTTSCTKLAVYYKKRGFKVGLVCADTFR 158 Candida albicans
O15821    79 VFEELINLVDPKTEA-----------------FKPKKGKTCVLMMVGLQGAGKTTTITKLALYYKNRGYKPAVVGADTFR 141 Entamoeba histolytica
CAA34386  79 VFKELVKLVDPGVKA-----------------WTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFR 141 house mouse

P49969   142 AGAFDQLKQNATKAKIPFYGSYMESDPVKIAVEGLERFRKENSDLIIIDTSGRHKQEAALFEEMRQVAEATKPDLVIFVM 221 Hordeum vulgare
O42816   159 AGAFDQLKQNAIKANIPYYGSYLEPDPVKIAFEGVQKFKQEKFDIIIVDTSGRHRQEEQLFTEMVQIGEAVQPTQTIMVM 238 Candida albicans
O15821   142 AGAYEQLQMNAKRAGVPFFGIKEESDPVKVASEGVRTFRKEKNDIILVDTSGRHKQDKELFKEMQSVRDAIKPDSIIFVM 221 Entamoeba histolytica
CAA34386 142 AGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEERLQVSNAIQPDNIVYVM 221 house mouse

P49969   222 DGSIGQAAFDQAQAFKQSASVGAVIITKLDGHAKGGGALSAVAATKSPVIFIGTGEHIDEFEIFDVKPFVSRLLGMGDLS 301 Hordeum vulgare
O42816   239 DGSIGQAAESQARAFKESSNFGSIILTKMDGHAKGGGAISAVAATKTPIVFIGTGEHVGDLEIFKPTTFISKLLGIGDIQ 318 Candida albicans
O15821   222 DGAIGQAAFGQAKAFKDAVEVGSVIITKLDGHSNGGGALSAVAATKSPIIFIGTGEKVNEIEEFDAESFVRQLLGMGDLK 301 Entamoeba histolytica
CAA34386 222 DASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIE 301 house mouse

P49969   302 GLMDKIQDVMPADQQp--ELLAKLAEGTFTLRLLYEQFQNLLKMGPIGQVFSMLPGFSsELMPKGHEKEGQAKIKRYMTI 379 Hordeum vulgare
O42816   319 GLIEHVQSLNLHQDEghkQTIEHIKEGKFTLRDFQNQMNNFLKMGPLTNIASMIPGLS-NIMSQVGDEETSKKIKNMIYI 397 Candida albicans
O15821   302 GIAKLAKDFAENAEYk--TMVKHLQEGTLTVRDWKEQLSNLQKMGQLGNIMQMI-GLNhPMFQGGNIEK---KFKVFMVI 375 Entamoeba histolytica
CAA34386 302 GLIDKVNELKLDDNE---ALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGtDFMSKGNEQESMARLKKLMTI 378 house mouse

P49969   380 MDSMTAAELDSTNp-KLMTE--SRIIRIARGSGRQIRDVTDMLEEYKRLAKM 428 Hordeum vulgare
O42816   398 MDSMTTKELECDG--RIFIKepSRIVRVARGSGCAVVEVEMILQQHRMMSTM 447 Candida albicans
O15821   376 LDSMTDRELDGSA--KTMLNdeSRIRRLARGSGRDIREVNELFEQIKLFQQC 425 Entamoeba histolytica
CAA34386 379 MDSMNDQELDSTDgaKVFSKqpGRIQRVARGSGVSTRDVQELLTQYTKFAQM 430 house mouse
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap