Conserved Protein Domain Family
MADF_DNA_bdg

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pfam10545: MADF_DNA_bdg 
Alcohol dehydrogenase transcription factor Myb/SANT-like
The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.
Statistics
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PSSM-Id: 463144
Aligned: 64 rows
Threshold Bit Score: 61.5337
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9XV35        12 LINAIRNRPVIWDKNYfGESNYRTLKTSCLREVTSELnsMFqmP----IKFtcedVRSQWKNLKDTFVRKLRWVHeg--- 84  Caenorhabditis ...
Q9W1E7        32 LIELYRSSDCLWNHYS-ELYKNKDCRAKAIESICASL--Ei--T----KHD----YGKKVHNLRNQFNAELKKLErrle- 97  fruit fly
XP_001628368  28 LITLWREHEELYDLRH-VDYPKRDRRRLAFKHISEQL--Gi--T----VPE----IKKKMTNLRTYYTKEIWKERpggkm 94 
XP_001625193  35 LIKLWEEENVLYNGRHkDHFRREC-RSAAMDRIQQRL--AEdgD----LLFtleeLHKKMRCLRTYYSKEIKKEKisk-- 105
Q9VXQ6       259 LIHSYQRNPFLWDHGN-AQFRDRVKRARFLDWIVLEF--KSrfNislaKDA----ITRKWDNLRTVYKRECNRMA----- 326 fruit fly
XP_002020339  16 FIEQYQEEECLWQPKH-NDYSNHAARNKSYDRLVEKL--KEveP----NPDrp-mVVRKINSLRSAFRREYRKTT----- 82 
Q9W0P0        20 FLALYQGMPELWDVHH-LNYRNKELRNRAYELLERKL--REiqPna-tRTE----VGRRINIFRTNYRREQMRILkqk-- 89  fruit fly
Q1LZ24       202 LIQAYKEHPCLWNPSD-EHYQDEPARSMAYEAIMERM--DRkaNvlftVEE----LKKTLEQLHVQYTLALETKQ----- 269 fruit fly
Q5BIC3       166 FIELYKQQTCLWDPAD-ESYRDKEKRANAYEELLEQL--KAtvN----LHLtaykLKKCITSLHAQYASISRQKK----- 233 fruit fly
NP_001163089 595 FVEIYHNYSALWDVDH-PDFRSNTYRSQALGQMLDEI--NTtfHtsytAEQ----LEKTLFNLRKEFSAQKRKIL----- 662
Q9XV35        85 --kYMEDAMKEPTWKFYRMLTFL 105 Caenorhabditis elegans
Q9W1E7        98 esgGDRDSEKACRWEHFKTLMFL 120 fruit fly
XP_001628368  95 gtdEPSKEPYISRWQHIHSLSFL 117
XP_001625193 106 lnsSNPQDLYTSRWPLYHSLHFL 128
Q9VXQ6       327 -----LEKTNISTLWYFKELHFL 344 fruit fly
XP_002020339  83 -----CKSDYETRLWYYDRLLFI 100
Q9W0P0        90 -elGLHSDLCKPTLWFYDYMGFL 111 fruit fly
Q1LZ24       270 -----RGKLVGLAARYFAKCEFL 287 fruit fly
Q5BIC3       234 -----TQKLTKVPLYYHGKYSFL 251 fruit fly
NP_001163089 663 ---TESEDSSSIPLLHAKLAEFL 682
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