1WPM,4RPA


Conserved Protein Domain Family
DHHA2

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pfam02833: DHHA2 
DHHA2 domain
This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members. The domain is about 120 residues long and contains a conserved DXK motif at its amino terminus.
Statistics
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PSSM-Id: 460719
Aligned: 445 rows
Threshold Bit Score: 39.1022
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1WPM_A        184 MLKAGADLSKKTVEELISLDAKEFT----LGSKKVEIAQV-NTVDIEDVKK-RQAE------LEAVISKVV-AEKn-LDL 249 
XP_002075253  226 LRAARADISQLSLVQVLRKDMKIVH----TARQQVPMAGL-PLLARDFVARd---------gAEEAVREFG--RG--SDL 287 
XP_001846780  227 LVAKRSDVSSLDSLQILSKDLKIVS----KNGITVAIPGY-PILVQEYIKLd---------gVGENLRKFAdKTN--SNV 290 
Q7QAC2        208 LVDARSDVSELNAYQLLLKDLKIIS----QNDRTVAVPGF-PMAVQEYIKLp---------eWREHLNRFAtSTE--SNV 271  Anopheles gam...
ETN63451      230 LVAARSDISQLNAYQLLFKDLKILN----QNGRIVSLPGF-PMAVQEYLKLs---------eCSQHVNQFAcSTQ--SNV 293 
EFN75302      234 LMKAKTDISELTIEELMIKDLKITN----G----VPVAVF-PLLVENLLMKe---------nAKEIIEKFSiDKN--WTV 293 
XP_015783541  234 ITAIGKASSMLGLTDLLTKDLKIIDg---IGGKKVALSSLcNIHLKETLSKpD---------ISAQLGQYC-RANncLGS 300 
XP_009014926  152 ILVAKDQISGLTLEEILRKDLKFADkminNHMVKIAIPVI-RINIHDFFEEnSDVEg----rIKKQLEMFNs------SA 220 
XP_002131728  240 LAKAKFSIEGLNAHEMLLKDPKIIEn--pSNTFRVMFSTL-HQDQNSFFQReDAKAailsnlETQNLQSWIs-----LSS 311 
3_pfamImport    3 LNRAKFSVEGFNAMDMLHKDAKVIEn--qNCTFSVMFSTL-HQHNSAFFSRpDAKSaiesnlETAKVQAWIs-----LAP 74  
1WPM_A        250 FLLVIT-------DILEndSLALAI-------GNEA---AKVEKAFNVTLENNtALLK------------------GVVS 294 
XP_002075253  288 VCILGMyvlpddgQVQR--DVALISltpesqlIKR------LQQTLVEHANPK-LGLFpydndikfm-ngcflsqrNVQA 357 
XP_001846780  291 IVLMGMkvt--dgSVQR--DLGIINinn-eklHQE------ILNKLTSSVSPD-FAFKkhdhvtme---gsffqqcNVRV 355 
Q7QAC2        272 VILLGMkvh-pdgSVRR--DVGVIPidg-tplAEK------IIAALHASQEMN-FELEeipcsen----gtfyqqhNLRA 336  Anopheles gam...
ETN63451      294 VLLLGMkvl-pdgSVRR--DIGIIPidd-kplAEK------IISALLEDNATS-FGLErietdfan--gaaffqqhNLKA 360 
EFN75302      294 IVLIGLnvs--dgHISR--DIAIFStlc-nqlGHD------IIQALISSTQPH-LNTElikeirekrysiclyklgNVEV 361 
XP_015783541  301 ILLAIRnen--pnNVER--DLAIYFsle--dlLRK------VCNQLESS-ACA-LDLEllfeken----lkvykqnNVKA 362 
XP_009014926  221 LIIMFMdt---kvNLRR--FIAVYS-------Y-ENdilEKLINGLVNS---KtVDLKfqkiivknsenficfeqlNISA 284 
XP_002131728  312 VSIDHEg------HKYK--PIAVHC-------PNDEq-rERITTALIEAESLD-IGLDtdcserfn--yciflrmyNCKA 372 
3_pfamImport   75 ITVDSEs------RTYK--VLAVYC-------PNDEk-rEKIIEALTAADSLE-IQIDkhnqqafn--scvilrmyNCQA 135 
1WPM_A        295 RKKQVVPVLTDA 306 
XP_002075253  358 TRKHILPVVRQV 369 
XP_001846780  356 TRKHLLPLVTSV 367 
Q7QAC2        337 SRKQLIPIVKNV 348  Anopheles gambiae str. PEST
ETN63451      361 SRKQLIPIVKNV 372 
EFN75302      362 TRKQILPIVHKT 373 
XP_015783541  363 SRKAILPMIAQI 374 
XP_009014926  285 SRKVLLPLIENF 296 
XP_002131728  373 TRKQLLPVVDNL 384 
3_pfamImport  136 TRKQIIPVVNKL 147 
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