Conserved Protein Domain Family
ccoG_rdxA_fixG

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TIGR02745: ccoG_rdxA_fixG 
cytochrome c oxidase accessory protein FixG
Member of this ferredoxin-like protein family are found exclusively in species with an operon encoding the cbb3 type of cytochrome c oxidase (cco-cbb3), and near the cco-cbb3 operon in about half the cases. The cco-cbb3 is found in a variety of proteobacteria and almost nowhere else, and is associated with oxygen use under microaerobic conditions. Some (but not all) of these proteobacteria are also nitrogen-fixing, hence the gene symbol fixG. FixG was shown essential for functional cco-cbb3 expression in Bradyrhizobium japonicum.
Statistics
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PSSM-Id: 274278
Aligned: 15 rows
Threshold Bit Score: 549.217
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
tigr:BR0359  38 FRRFKWIVMFITLGIYYLTPWLRWDRgayapDQAVLIDLANRRFYFFFIEIWPQEFYYVAGLLIMAGLGLFLVTSVAGRA 117 Brucella suis 1330
AAN69144     35 YRNLRIGFAGALFVLFFGTAWLNWNG-----RQAVLWDLGNSKFHIFGATFWPQDFILLSALLIICAFGLFAITVYAGRV 109 Pseudomonas puti...
AAN69839     39 FRRLRMVGGAVLFLLYFGTVWLNWEG-----HQAVWWNLPERKFYIFGATIWPQDFILLSGILIVAAFGLFFITVFAGRV 113 Pseudomonas puti...
AAV96747     26 FRNLKWVIMAVTLGIYYLTPWIRWDRgpslpDQAVLLDMANRRFYFFWIEIWPHEFYFVAGLLIMAGLGLFLFTSALGRV 105 Ruegeria pomeroy...
BAC51043     27 FRRIKWAILCVTLGTYYLLPFVRWNRgpglpDQAVLIDLPHRRFYFFFIELWPQEVYYFTGLLIIAAMTLFLMNAVAGRL 106 Bradyrhizobium d...
AAK23386     49 WRMVKWALLIATLSVYYITPWIRWGRpegfpQQAALVDFTGRRFYFFDIQLWPQEVYLFTGVLIAAALALFLTTALFGRL 128 Caulobacter cres...
CAE80407     30 FRRHRDWTQIVLLIIFLILPWTTFNG-----HQTILMDIPKREFALFGILFKAHDAPLLFYIVGTLTLGLAFVTSIWGRV 104 Bdellovibrio bac...
CAD74747     68 WWKRRRVIAYILMVVFVAIPHLRIGG-----KPLILLDIAAREFTVLGKTFYPTDTLVLALFMLSIFVSIVLITAITGRA 142 Rhodopirellula b...
CAE09765     16 YYKKRYWVFALITLVAMGLPFIQIDG-----NQLFLLSFDKKQLHLLGVAFDMQELYLMPFLLMLLFLGIFFVTTLAGRV 90  Wolinella succin...
AAP77510      8 YRIKRYIVYGVATLFLLIFPFIQING-----NQLFLLSFDHKQLHLMGVVFDMQELYLMPFLLILMFVGIFFMTTLAGRI 82  Helicobacter hep...
tigr:BR0359 118 WCGYTCPQTVWV-DLFLVVERAVEGDRNAR-MKLDKAP-WTFDKVWKRLAKHSIWIVIGVLTGGAWIFYFADAPTLLKDF 194 Brucella suis 1330
AAN69144    110 WCGYSCPQSTWT-WLFMWCEKVTEGDRNQR-IKLAAAP-WSLNKLARRTLKHSLWLAIGVLTGLTFVGYFTPIRPLAAEL 186 Pseudomonas puti...
AAN69839    114 WCGYTCPQSVWT-WIFMWCEKITEGDRNQR-MKLDKAP-MSGNKFLRKFAKHSLWLLIGFVTGMTFVGYFSPIRELAIEF 190 Pseudomonas puti...
AAV96747    106 WCGYACPQTVWT-DLFILVERWIEGDRNAR-LRLHRQEkLDFRKARLRITKWAAWLLIGLATGGAWIFYFADAPTLLSDL 183 Ruegeria pomeroy...
BAC51043    107 WCGYMCPQTVWT-DLFYAVERWVEGDRRER-MQGDKRY-WTFDHIRKVVLKHFLWIMIAWWTGGAWVLYFSDAPTLVKEL 183 Bradyrhizobium d...
AAK23386    129 WCGYACPQTVWT-DLYIVVERLFEGDRNAR-MRLDAAP-LSFDKIWRKTGKHLTWLGIAFGTGGAWIFYFHDAPTLIRTF 205 Caulobacter cres...
CAE80407    105 WCGWACPQTVFIdAVYRRIEKWVEGTYIQR-RQLRDGP-MNFTKVRKLSLKWFLFFAVSSVIAHSFIAYFVGAQELLAMT 182 Bdellovibrio bac...
CAD74747    143 WCGWACPQTVYMeFLFRPIDRFFDGTLGKG-GKPARG----ISPVWQIAR-FAVYLVLCMFLAHTFLAYFVGTEKLAQWV 216 Rhodopirellula b...
CAE09765     91 WCGWGCPQTIFRvIYRDVIETKLLGLRKRIdNKQQEPDmSLPINKLKKGAALLIWIGISVVAASNFLWYFIPPADFFTYL 170 Wolinella succin...
AAP77510     83 WCGWACPQTIFRvLYRDLLQTKIFGLRKKIsNKQEKMDlSTFGDKIKAVLAFLIMATLCLVAAANLMFFFTPPSDFFAYM 162 Helicobacter hep...
tigr:BR0359 195 VTGHAAPVAYFTVAILTATTYIFGG-LMREQVCTYMCPWPRIQAAMLDENSLTVTYNDWRGEPRS--RHSKKAIAAGe-- 269 Brucella suis 1330
AAN69144    187 LTLQLGGVALFWVLFFTAATYINAG-LLREAVCLHMCPYARFQSVMFDKDTLAVAYDPRRGEARGprKKGSDVGAQG--- 262 Pseudomonas puti...
AAN69839    191 FTGQADGWAYFWVGFFTLATYGNAG-WLREQVCVYMCPYARFQSVMFDKDTLIVSYDPRRGETRGprKKDTDYKAQG--- 266 Pseudomonas puti...
AAV96747    184 VTGNAHPIAYTTMAVLTFTTFFFGG-FAREQICIYACPWPRIQAAMMDEDTLVVGYREWRGEPRG--KGKRTEDSE---- 256 Ruegeria pomeroy...
BAC51043    184 ATFQAPFIAYLWIGILTATTYVFAG-HAREQMCIYMCPWPRIQAALTDEWALNVTYRRDRGEPRMsvKKADAARAHGd-- 260 Bradyrhizobium d...
AAK23386    206 WIGQAPATAYVSCALLTATTYIFAG-WMREQVCTYMCPWPRIQGAMLDQHSLQVTYLRERGEPRGahKKGQSWEGR---- 280 Caulobacter cres...
CAE80407    183 QGSPAQNMTYFVLVLFFTSVILFDFgWFREQFCVIMCPYGRIQSVLLDQKSLAVVYDVNRGEPR---KGTTEPNq----- 254 Bdellovibrio bac...
CAD74747    217 RSSPIDHPSAFLVMAATTGLMLFDFlFFREQLCLIACPYGRFQSVMLDEQSKIVAYDPVRGEPRIkgKRTHDDDRGVdlv 296 Rhodopirellula b...
CAE09765    171 SN-PAEHTILITFLAVLVAVMVFDIiFIKENFCVYMCPYSRVQSVLYDNDTIMTVYDYERGGKVFdpKGIKLWKKPet-- 247 Wolinella succin...
AAP77510    163 SD-PLNHRILLGFWLGFGLFFILDIaYIQENFCIYMCPYCRVQSVLFDDDTITAVYDYKRGGAVYdtKGMKFDIAPKkq- 240 Helicobacter hep...
tigr:BR0359 270 ---tVGDCVDCNACVAACPMGIDIRDGQQLECITCALCIDACDSVMDKIGKPRGLISYATLAdydanmalaTNNGIAPTD 346 Brucella suis 1330
AAN69144    263 ----LGDCIDCTLCVQVCPTGIDIRDGLQMACIGCAACIDACDGVMDKMGYARGLIGYKSEH---------SLQGGTTHW 329 Pseudomonas puti...
AAN69839    267 ----LGDCIDCTMCVQVCPTGIDIRDGLQIECIGCAACIDACDSIMDKMNYPKGLISYTTEH---------NLSGQKTHM 333 Pseudomonas puti...
AAV96747    257 ----LGDCIDCMACVNVCPVGIDIRDGQQLECITCALCIDACDDMMEKIGKPRGLIDYMALKde-----eaERAGHPPKN 327 Ruegeria pomeroy...
BAC51043    261 ---rAGDCVDCHQCINVCPTGVDIRNGIQLGCIQCGLCIDACDNVMREIGRPAGLIGYDTDInm-----qrRREGKAPLY 332 Bradyrhizobium d...
AAK23386    281 -----GDCIDCRQCVVVCPMGIDIRDGSQLECINCGLCVDACDDILGKLGRPTGLIAYDTDAav-----aaRTCGQKAVY 350 Caulobacter cres...
CAE80407    255 ---kAGDCVSCNRCVQVCPTGIDIRNGLQMECITCTACIDACDEIMEKVKKPKGLIRYDTLD------------GSKis- 318 Bdellovibrio bac...
CAD74747    297 rgkaAGDCVDCHQCVVVCPTGIDIRDGLQMECINCTQCIDACDDVMEKVGKPKGLIRYSSQD------------AIARKP 364 Rhodopirellula b...
CAE09765    248 ---pNAECTGCELCVKVCPTHIDIRKGMQLECINCLECADACTKVMGKLGKE-SLIGWTSPQ---------AVETREKVR 314 Wolinella succin...
AAP77510    241 --dpNNECTNCLACVRVCPTHIDIRKGMQLECINCLECADACAKVMDKLGRP-SLVMWKSFA---------SLDNNGKVR 308 Helicobacter hep...
tigr:BR0359 347 parvyeapnkfsdkvqnlswkkvLRPRSMFYFAIWALIGVVLIVSLSTRQRIGINVLHDRTPQYVLL----SDGSIRNGY 422 Brucella suis 1330
AAN69144    330 -----------------------LRPRLLGYAAALLVMIGALVVALQMRPMVSLDVIKDR-GLFREN----AQGQIENIY 381 Pseudomonas puti...
AAN69839    334 -----------------------LRPRLIGYAVVLLVMMIGLATAFATRSLVGFDVSKDR-VLYREN----AQGRIENVY 385 Pseudomonas puti...
AAV96747    328 iwk------------------hiLRPRTIMYTSLWSLVGFGLLFALFIRSDIDLTVAPVRNPTFVTL----SDGSIRNTY 385 Ruegeria pomeroy...
BAC51043    333 r---------------------iIRPRTLTYAAAIAIVGGIMLYALATRTTMDVNVLHERNPLFVQL----SDGGVRNDY 387 Bradyrhizobium d...
AAK23386    351 k---------------------pVRSRTVYYAVALALVGGLTLWSLVTRPKADLHVIRDRNPTFVRM----HDGAVRDGY 405 Caulobacter cres...
CAE80407    319 ----------------------lAKPRSIIYILAIVALIGGLAYAVSTREPVHIAVLRGAGLPYSYVknsdGQEVLLNQF 376 Bdellovibrio bac...
CAD74747    365 kk--------------------lLRARTIIYPIVLVGVFSGLAMAISSKSGFDARILRGRGAPYSLL----GAKEVSNAF 420 Rhodopirellula b...
CAE09765    315 y----------------------FRFRTIAYMVALVIVMGALVVMSGKKEHMLLNINRTTELYSIKEq-----gMVENSY 367 Wolinella succin...
AAP77510    309 v----------------------MRFKTIGYTIILALVFVLLLFMGTTKEGMLLNISRTSELYEVRNh-----hIVDNHY 361 Helicobacter hep...
tigr:BR0359 423 TVKLLNMIPTPRTFQLSIQG------LPEATLTVQDetpdangnyAIAVEPDKLKNLRVFVTMP----HDAVTEPRKdyE 492 Brucella suis 1330
AAN69144    382 LLKVINKTERTQHYQLRLLD------ADGFTLQGSS---------ALVIPAGEMSELPVSVAML----AERPSSSSQtlS 442 Pseudomonas puti...
AAN69839    386 SLKVMNKDQRDHLYVLDAAG------LPDLKLEGQR---------EIRVAAGDIVSLPVQLSVA----PEKLPSTTNeiT 446 Pseudomonas puti...
AAV96747    386 DVRLRNKHGEERPFQLSVVG------DPSMRIELEGlpd-----enVSVPADTAFLQRVYIVTP----KDAAPSQAAstD 450 Ruegeria pomeroy...
BAC51043    388 TVRILNKG-AQRSFALEVSG------LPGATVRVAGieagsdgkpVIEVGQDQTREIRLSVQVG----PGDLP--KTsrD 454 Bradyrhizobium d...
AAK23386    406 TLKITNRTFAERRFDVTFEG------VAGARLSQPGqtaq---rvtLIVPADQVVSARVFVTAP----ADADLa----sS 468 Caulobacter cres...
CAE80407    377 RLHIQNQGALRARYMLTLPQel---lDQGVQVQVAEn--------PIHLAPGESREWYFFVRIPt---VQIPASGQLktE 442 Bdellovibrio bac...
CAD74747    421 NLRLVNRTEIAQTYELSTN-------DSSVEVEIIDa-------dAQHLEPAESKLLPIRLNFPs---SMTMGDGNEsiE 483 Rhodopirellula b...
CAE09765    368 VFLFQNTDKVAHDYYFEILDn------pKIKIKRPEe--------PFTLEPGKKVKKVVVLYTeerlsEDGRKDTPVpiK 433 Wolinella succin...
AAP77510    362 TMLFHNTDANDHEMYFEVLDvkgndiAHSLKIITPKa--------PFKVKAGKKEKKVVTLRTeevlqKG-----SYdiI 428 Helicobacter hep...
tigr:BR0359 493 IEVRAEDGSEGAR-YKATFMAP 513 Brucella suis 1330
AAN69144    443 FEISERDDPA-IRsVAHSRFVA 463 Pseudomonas putida KT2440
AAN69839    447 FILKSADDSD-AQvEAKSRFIG 467 Pseudomonas putida KT2440
AAV96747    451 VRIWVEDQSNGERaYKDTTFNG 472 Ruegeria pomeroyi DSS-3
BAC51043    455 VGIAITDTAGGGRaSARDHFVP 476 Bradyrhizobium diazoefficiens USDA 110
AAK23386    469 VPARFIAKSGDIItQSKTVFLS 490 Caulobacter crescentus CB15
CAE80407    443 VRVQDELAPEGFStRRELILVG 464 Bdellovibrio bacteriovorus HD100
CAD74747    484 LTVKDQSGNERIIs---MKVLG 502 Rhodopirellula baltica SH 1
CAE09765    434 IHAYALDKKEEISvFRDSVFVY 455 Wolinella succinogenes
AAP77510    429 IRAFAIDDKEHIFvERKTNFVY 450 Helicobacter hepaticus ATCC 51449
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