Conserved Protein Domain Family
MSL2-CXC
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pfam16682: MSL2-CXC 
CXC domain of E3 ubiquitin-protein ligase MSL2
MSL2-CXC is an autonomously folded domain containing that binds three zinc ions. It lies on the E3 ubiquitin-protein ligase MSL2 in eukaryotes. The CXC domain critically contributes to the DNA-binding activity of MSL2. It carries 9 invariant cysteines within about a 50 residue region.
Links
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Statistics
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PSSM-Id: 435512
Aligned: 11 rows
Threshold Bit Score: 84.0251
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDW28546             818 EKPPKPICRCGTSGVaVNPKtTCRNTRCPCYKSGNTCTNCHCVGCHNPHKTDFLDS 873 
XP_002064454         753 DPKQRKHCRCGISGP-STPK-TCRNNRCWCYINGNSCTDCSCQGCNNPHKQDYIDT 806 
WGS:AAQB:GK11737-PA  450 NQKQRKVCGCGQKVG-QKKRnVCRSNRCYCYSNGYSCSDCNCQGCKNPLKSD-INP 503 
EDX16256             110 VKPPKPKCRCGISGS-SNTLtTCRNSRCPCYKSYNSCAGCHCVCCKNPHKEDYVES 164 
XP_001965093         443 RKEEKSLCRCGISNS-KKPLmTCRNNRCPCYKAGNSCANCHCVACKNPHKVDFIDS 497 
XP_002013250          70 EDPFKHKCRCGTSGVlANPKtTCRNNRCRCYVSGNSCRNCRCFGCHNPHKTDLLDS 125 
EDO64317             564 QALKRKGCRCGNATP-TPGKlTCCGQRCPCYVDSKSCVDCKCRGCRNPHRADGLKI 618 
XP_003243452         259 KNERRWGCRCGNATT-TPGKlTCFGQRCPCYTEQKPCDQCKCRGCRNPRQKRSNND 313 
BAA91673              48 KPQEKKGCKCGRATQ-NPSVlTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKK 102 
EEN51211             194 pPPEKRSCRCGTFCE--PSElTCHRQRCPCYSNQLSCTGCRCRGCKNPYKDDSVRK 247 
XP_015020409         624 DARMSHICRCGTTSA--PGKaTCRNSRCTCYVAGKSCVDCKCIGCKNPHQ-DATDT 676
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