Conserved Protein Domain Family
ArfB_arch_rifla

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NF033501: ArfB_arch_rifla 
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
MJ0116 from Methanocaldococcus jannaschii, the founding member of this family, was shown be 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase, catalyzing the second step in archaeal riboflavin and Fo biosynthesis.
Statistics
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PSSM-Id: 411143
Aligned: 12 rows
Threshold Bit Score: 293.84
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q2NF45   7 KLKYDSGNILSK--DVHSIGIIALGSHRENHGAALPIDTDSKIAANVALNVATKTGATFLGIFYGATEYDYIKHGHHLKK 84  Methanosphaera stadtm...
A5UJL1   3 ELRYRAGKIKNP--RVHKIGVIALGSHLENHGPALPIDTDAKIGAHIAFQASLESGAKFLGIVFPAYELDEIDHGVHVSL 80  Methanobrevibacter sm...
D3E3M2   3 ELRVNAGNVKNP--NVHKIGIIALGSHLENHGPALPIDTDAKIASHIAFQASLESGAKFLGVIYPAHELKEINHGIHVSL 80  Methanobrevibacter ru...
E3GWT5  15 KLNYDAGNIISP--KVHSVGVLALGSYLENHGPVLPIDTDIKIASYLALNASIKTGAKFIGTVYPATEYPYVKHGIHVSV 92  Methanothermus fervid...
O26747   4 ELNLDAGNIISE--DVHRIGILAVGSHLENHGPALPIDTDAKIASYVALEAALRTGARFLGVLYAASEFPYVKHGIHMDR 81  Methanothermobacter t...
D7DV18   5 ELRLNSGKLIDNdsKVHEIGVIAMGSYLENHGSALPIDTDIKIASYVALNVALTTGAKFLGTVCTATEYDYIKHGIHNSL 84  Methanococcus voltae A3
A6UQY8   5 ELRYNSGNILNE--EVHKIGIIALGSFLENHGSALPIDTDAKIASYIGLNVSILTGAKFLGVVIPSTEYSYVKHGIHNSP 82  Methanococcus vanniel...
A6VHX1   3 DLRYGSGNIFNE--KVHGIGIIALGSFLENHGSALPIDTDAKIASYIALNVSIITGAKFLGVVLPSTEYSYVKHGIHDSI 80  Methanococcus maripal...
D5VQW1   3 ILRLNGGKILNE--KVHEIGVIAMGSYLENHGSALPIDTDIKIASYVSLMACIKTGAKFLGTVIPSTEYSYVKHGIHNKV 80  Methanocaldococcus in...
C9RGE3   3 EIRLSSGKILNK--KVHKIGVIALGSFLENHGAVLPIDTDIKIASYIALNASILTGAKFLGVVIPSTEYEYVKHGIHNKV 80  Methanocaldococcus vu...
C7P7V6   2 ELRLSSGNILDE--KVHKVGIIALGSFLENHGAVLPIDTDIKIASYIALKAAILTGAKFLGVVIPSTEYEYVKHGIHNKP 79  Methanocaldococcus fe...
A6UUS5  20 NLRLTSGKIINK--NVHQIGIIALGSYLENHGTVLPIDTDIKIASYIALNVAIQTGAKFLGCVLPSTEYEYVKHGIHNTP 97  Methanococcus aeolicu...
Q2NF45  85 DDLVNkQIIPQLINIKKqLNIKSVIIVNGHGGNNLIIEDIDKISKKT-------------------------------EL 133 Methanosphaera stadtm...
A5UJL1  81 DELKA-NVISTLNSAKKyLDIEKVVIVNSHGGNIPLMTELYDIEDKT-------------------------------DL 128 Methanobrevibacter sm...
D3E3M2  81 EDLTD-EIVKVLKSAKKfLRISSVIIVNGHGGNLPIVTTLYDIEERT-------------------------------GL 128 Methanobrevibacter ru...
E3GWT5  93 KDLIE-NIVSIMKLANKyIGIDKSVIVNAHGGNLPLKKHINVIERET-------------------------------GM 140 Methanothermus fervid...
O26747  82 DELVErELKPVLRKARRlLNLEAAVIVNGHGGNKL-EDCMDDLEEEL-------------------------------GL 129 Methanothermobacter t...
D7DV18  85 EDILE-ELEEIIIKYSK-IGVNKFLIINCHGGNSDVSKKIEQLQEKIrnnfkeygttekeleyikkikynfkeygnteKI 162 Methanococcus voltae A3
A6UQY8  83 NEVVE-YIKIMIEHSKK-IGINKFLIINCHGGNTLIKDLISELNDK--------------------------------KT 128 Methanococcus vanniel...
A6VHX1  81 KDVIN-YIKYLVENGRK-IGINKFLIINCHGGNTLIKDEISKLNHE--------------------------------NC 126 Methanococcus maripal...
D5VQW1  81 SDIVE-YLTFLLTWAKR-IGIKKVIIVNCHGGNILAEKEIKELENLI-------------------------------NI 127 Methanocaldococcus in...
C9RGE3  81 DEILD-YLRFMINWGKK-IGVEEIIIVNCHGGNVLIEEHLKNLEKEL-------------------------------DV 127 Methanocaldococcus vu...
C7P7V6  80 EDIYY-YLRFLINEGKK-IGVEKFLIVNCHGGNILIEKFLKDLEYEF-------------------------------GV 126 Methanocaldococcus fe...
A6UUS5  98 NEVVE-YIDFLVEQGKK-IGINKFLIINCHGGNTLINELIEELPYKS-------------------------------DI 144 Methanococcus aeolicu...
Q2NF45 134 KIIFNNSIIEsegpHACTGELSMGAVLGI--TDMTSLKEHENfIKHPEVGMVGLKEARDNEPIINKEALTIEKEG-FEVN 210 Methanosphaera stadtm...
A5UJL1 129 TIIFNNKIIStegpHGGSGELSMAKVLGI--INEAEIENQTDlSKYEEVGLYGFKQARENDPNIEEGARDVEENG-VYVD 205 Methanobrevibacter sm...
D3E3M2 129 LITLNSKIIEsegpHGGSGELSMAKALGI--IDESQVENQTNlEEYGEVGLYMFGEARRNDPNIEEGALDVEENG-VYVD 205 Methanobrevibacter ru...
E3GWT5 141 KIVMNNKIVEiegpHAGSGETSLGYVIGI--ADVERMNEIDF-KKYPEIGMVGLKSARKLNKKIDEGAKIVEKEG-VKIN 216 Methanothermus fervid...
O26747 130 EIAWNNRIVEiegpHAGSGELSAGLILGI--ADLRRLDECIP-ELYPEIGMIGLKEAREANREIDKAARICERDG-VNPD 205 Methanothermobacter t...
D7DV18 163 NIKIKSFGYI----HAYSEELSIGKCIGI--YDETKFNKHTP-ENYGEIGMVGLPEARLNNKYIDKEAKMVESIP-AVVN 234 Methanococcus voltae A3
A6UQY8 129 SVILENVCFT----HAAFEEIAIGYAVGI--LSEDKMKTHSF-KTYPEIGMIGLTEARLKNTDIDNEAKILEEKGaIFLD 201 Methanococcus vanniel...
A6VHX1 127 FIRMENVCLT----HAATDEVSLGYAVGI--LSEDKMKTHDP-EIYEEIGMVGLKEAREKNEAIDLEARSVEENG-VFLD 198 Methanococcus maripal...
D5VQW1 128 KIKFLSFPLT----HAATEELSIGYVIGI--ANKEKMKEHKP-ENYAEIGMVGLREAREKNKEIDEEAKRVEKEG-VKID 199 Methanocaldococcus in...
C9RGE3 128 SIEMINITFT----HASTEEVSVGEVIGI--SDVKRLEEHTNfEKYPEVGMVGLKEARRNNPIIDQEAKEVETSG-VKVD 200 Methanocaldococcus vu...
C7P7V6 127 KVEMINIAFT----HAATEEVSVGYVIGIakADEKSLKEHNNfEKYPEVGMVGLKEARENNKAIDEEAKAVEKFG-VRLD 201 Methanocaldococcus fe...
A6UUS5 145 KLKIKNITST----HASTEELSVGYVIGI--ADKSKLKEHNP-KDYPEIAMIGLTEARKNNKYIDNEAKIAEKKG-ITIN 216 Methanococcus aeolicu...
Q2NF45 211 MILGQDMLENAQKEIINEVKKL 232 Methanosphaera stadtmanae DSM 3091
A5UJL1 206 EVYGKQLFDLAINSVVFDIEKL 227 Methanobrevibacter smithii ATCC 35061
D3E3M2 206 DVYGQELLKLAINSVLLDVEKQ 227 Methanobrevibacter ruminantium M1
E3GWT5 217 PKLGRKLLNIALNDIINDIKHL 238 Methanothermus fervidus DSM 2088
O26747 206 PVLGQRILDDAVESVISDVKEL 227 Methanothermobacter thermautotrophicus str. Delta H
D7DV18 235 EQYGEELIKKMVNESIEYIREF 256 Methanococcus voltae A3
A6UQY8 202 KNYGKTLLKNLINNHVEIVKKM 223 Methanococcus vannielii SB
A6VHX1 199 RTHGRFLLNELINNYVEIVRNM 220 Methanococcus maripaludis C7
D5VQW1 200 EELGKKLLDEFINKVVNEITNF 221 Methanocaldococcus infernus ME
C9RGE3 201 RELGRSILKNAIEKVVKKIEEK 222 Methanocaldococcus vulcanius M7
C7P7V6 202 KNLGEKILNDAIEKVVDKVKEM 223 Methanocaldococcus fervens AG86
A6UUS5 217 EDLGNKILKNAINECILEVELL 238 Methanococcus aeolicus Nankai-3
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