1KYH


Conserved Protein Domain Family
YXKO-related
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cd01171: YXKO-related 
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B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.
Links
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Statistics
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PSSM-Id: 238576
Aligned: 127 rows
Threshold Bit Score: 106.928
Created: 10-Jan-2006
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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putative ATPputative
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:putative ATP binding site [chemical binding site]
Evidence:
  • Comment:based on homology to other members of superfamily
  • Citation:PMID 9519409
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                     
1KYH_A     20 AESHKGt----------yGTALLLAGsdd-xpGAALLAGLGAXRSGLgKLVIGTSenvip--------livpvLPEATYw 80  Bacillus subtilis
P32740     13 PHLRKGd----------cGKMGVIGGsle-ytGAPYFAASSASRLGAdLIHIFCDpdaaq--------vikgySPDLIVh 73  nematode
NP_568369  66 LKRHKGq----------aGKIAVIGGcre-ytGAPYFAAISALKIGAdLSHVFCTkdaap--------viksySPELIVh 126 thale cress
NP_597647  19 FTSNKKgd---------sGTVLIIGGcry-ytGAPYFASLAALFTGSeLVYIFSEpeaiv--------slktlLPESIVc 80  Encephalitozoon cu...
EAA22075   37 ENGYKGy----------fGKICVIGGnei-ysGAPFLSALTTLRLGAdLCFVVSSkecst--------hlknySPELIVy 97  Plasmodium yoelii ...
NP_701309  39 KDEYKGc----------sGKICVIGGsev-ysGAVYLSSISTLKIGGdLCFVITTdenky--------plksySCELIVy 99  Plasmodium falcipa...
EAA39595    6 YTLHKGq----------rGRPLLIAGspk-yhGAPILAGLSCLRAGAdYCYLLVRgsnsq--------ivasaSPNFIVs 66  Giardia lamblia AT...
CAF31096   12 MELIKGpvklnkdtfeikNKELPISMgtcallGAAFKTLEYFGKEDE-LTFITAGdvgegdgsleiyeelheiNDDLTIi 90  Methanococcus mari...
EAK91586   23 PNFHKGq----------aGKIVVIGGned-ytGAPFFASHSAALVGAdLSHVICEkaagp--------viksySPDLMIh 83  Candida albicans S...
AAT12360   53 RDAVKGe----------rGTVLILGGshe-ytGAPYFAAMGSLRAGAdLVYVFAQeeavq--------siktlIPEAIVm 113 Antonospora locustae

Feature 1                                                                                     
1KYH_A     81 rdgwkka-----------------------------------------adaqleeTYRAIAIGPGLpqt-----esVQQA 114 Bacillus subtilis
P32740     74 pgmtan------------------------------------------siipklsRMDAIVIGPGLgrnpn-iwplMQEL 110 nematode
NP_568369 127 pvleesysisqlseed----------------------krevqdkvlgevgkwmeRFDCLVIGPGLgrdpf-llecVSII 183 thale cress
NP_597647  81 tieyq---------------------------------------------ewllqKVTACVVGSGLgrps---eatCKEI 112 Encephalitozoon cu...
EAA22075   98 pylytnkfpkekn----------------------------nykdlencvkylsnRIDSCVIGPGLgnidketencLKYI 149 Plasmodium yoelii ...
NP_701309 100 pylytkksdikei----------------------------enspldkcikylleRIDSCVVGPGLgeidefteecLIYI 151 Plasmodium falcipa...
EAA39595   67 scld----------------------------------------------twkdiHYTNILIGPGLdte----eesVALF 96  Giardia lamblia AT...
CAF31096   91 hyikpki----------------------------------------seiikvdfSKNVIGDAGGMya------gkAAGI 124 Methanococcus mari...
EAK91586   84 pylmdldnphlnlnnseleklknlpideiiktndnavlnklidelilpkvtsllnRIDIVVVGPGFgrdpl-mlksLIRI 162 Candida albicans S...
AAT12360  114 tieyr---------------------------------------------ewvlrRITACAIGPGLgri----gdeTLKI 144 Antonospora locustae

Feature 1                                                         #                           
1KYH_A    115 VDHVlta----dcpVILDAGALAKRtypk--------------regPVILTPHPGEFFRXtgvpvnelqkkr-------- 168 Bacillus subtilis
P32740    111 FEFVrnr----dvpFVIDGDGLWFVsehiek---------fprqmsATVLTPNIVEFSRLcksalgeedvlnvrnn---- 173 nematode
NP_568369 184 MLLAkks----nvpFVIDGDGLFLVtnsidl----------vhsypLAVLTPNVNEYKRLvqkvlncevdeqna------ 243 thale cress
NP_597647 113 AKILsylsg-kgvpLVVDGDGIRLAerlgv------------rdfgTVIITPNHNEQKHIkki----------------- 162 Encephalitozoon cu...
EAA22075  150 IDIFiks----nifLILDADIIQFIitntylf-------nlvknykNCIFTPNKNEFKKMiyfltekkniqfnnlyt--- 215 Plasmodium yoelii ...
NP_701309 152 LEKFlek----nifLILDADIIQVImtnmkif-------nliknykNCLLTPNINELRKMlthlnnniinedvknidfkh 220 Plasmodium falcipa...
EAA39595   97 TDVMstk----psrLLLDADAIRIVcmllkqqdvvtsgllnqlsaaQSIITPNYAEFKHLyhsvfnsypsqyektisvlg 172 Giardia lamblia AT...
CAF31096  125 GNKFh--------mFFPDVGELAFLadensshpa---yvrgfiseiDDQEIPKLIKMAYTqk------------------ 175 Methanococcus mari...
EAK91586  163 IEEVkvl----nlpIILDADSLYLVslspki----------ianypKAIITPNVVEFQRIakalsidadlsesnkd---- 224 Candida albicans S...
AAT12360  145 ISLIlqylnsnevpLVVDGDGLRYYnenvf------------keykTMFLTPNINEKLKTrwi----------------- 195 Antonospora locustae

Feature 1                                                     #                               
1KYH_A    169 -------------------------------aeyakewaaqlqTVIVLKG-NQTVIAFpd----gDCWLNPTGNgALAKG 212 Bacillus subtilis
P32740    174 ----------------------------sqlqhlaaelsrkmnVTIYLKG-EVDLVVTpn----gEVSKCSTESsLRRCG 220 nematode
NP_568369 244 ------------------------------edqlrslakqiggVTILRKG-KSDLISNgetvksvSIYGSPRRCgGQGDI 292 thale cress
NP_597647 163 ----------------------------------------ekrVFYVQKG-PCDVVLWkd----sETRVDIEGC-PKRIG 196 Encephalitozoon cu...
EAA22075  216 ---------------------------nqiilygheiiklfngPKILIKD-SNDIFISkn----lFFISSIQNQsFKRLA 263 Plasmodium yoelii ...
NP_701309 221 ------------------------ltvykiiqyahalksvlnaPKILIKGfHDVYISDhf----fFVFFMKRQC-LKRSG 271 Plasmodium falcipa...
EAA39595  173 ksltsnwsgialgfialkglvkrgrkyynaltneptqlskklgVVILIKG-VVDVVVSpnp--cdAARVVTERGqPKRSA 249 Giardia lamblia AT...
CAF31096  176 -----------------------------------------mpKNMVVKG-SKDHIVNegn--iiETVEYPKFEaMECIG 211 Methanococcus mari...
EAK91586  225 ----------------------------klidqtievsrklgdIIVFRKG-EHDLIVKs-----sKFLINEITGsNKRVG 270 Candida albicans S...
AAT12360  196 ----------------------------------------kesHCLIEKG-RKDIIRLen----sCINVTERGS-VKRCG 229 Antonospora locustae

Feature 1      ##  #                                      #                           
1KYH_A    213 GTGDTLTGXILGXLCChed-------------pkhAVLNAVYLHGACAElwtdehs---ahtllaHELSDIL 268 Bacillus subtilis
P32740    221 GQGDVTAGSLGLFLYWakknlgdd----wtsahheAGIASSWLVRTAGRrafekhg---rsmntpLLLDEIP 285 nematode
NP_568369 293 LSGGVAVFLSWAQQLKsdpesps------enpailGCIAASGLLRKAASlaftk-------hkrsTLTSDII 351 thale cress
NP_597647 197 GQGDILAGTIASLVSKckapva-------gqdvfgSVVLGCIMVRRAGRlaykrhq---rslitrDILEELK 258 Encephalitozoon cuniculi
EAA22075  264 GLGDILTGLLAVFLAWgsk-------------kkeALLPEIKDKFLISDlceyhey---ldaistFNASYLL 319 Plasmodium yoelii yoelii
NP_701309 272 GFGDILTGIVSVFLCWaskiikq-----gielkdiISTKETFLSESFKDtvytnth---vqnndlLQTVAIF 335 Plasmodium falciparum 3D7
EAA39595  250 GQGDILAGILAALLARsvdesa-------lsicerAAILTRRASRAAYKhygesmv---asdviaYINMSDR 311 Giardia lamblia ATCC 50803
CAF31096  212 GTGDTLTGIASSLIACgfk-------------tekAGILGCKLNRKLGElvkprp----dtqiyeIIQKIPE 266 Methanococcus maripaludis
EAK91586  271 GQGDTLTGAIATLVNWsnnyilrlwdnqvdldqedANLLACFAASSVVRnasskafnkygrsmqtSNVHEYL 342 Candida albicans SC5314
AAT12360  230 GQGDILVGILCAIVSLlpkkrn-------keqliaCAECACKLTRLACRaaykekw---tsliasDILDKIP 291 Antonospora locustae

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