Conserved Protein Domain Family
RNR_inhib

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pfam08591: RNR_inhib 
Ribonucleotide reductase inhibitor
This family includes S. pombe Spd1. Spd1p inhibits fission yeast RNR activity by interacting with the Cdc22p.
Statistics
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PSSM-Id: 430095
Aligned: 40 rows
Threshold Bit Score: 38.5764
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EPE07517      59 NLLAVGMRVRKSVPEGYKTGK----------------EADERTTPSHYRPQPKAPSSYASsyrtflqs------------ 110
EMD94723      75 DLLSVGMRVRKSVPEGCKTHKmls-----------spADRFARARPRLDIKPPPEAVPD--------------------- 122
CBX99698     196 DLLNVGMRVRKAVPGGYKTQKlmsglptitttlvhspTTALA----DYEVKPSRDTVED--------------------- 250
EKG12242      59 SLLNVGMRVRKSVPEGYKTHKtlnp---------lsaTTTTAYYKPQTTTTPF--------------------------- 102
XP_007585271  54 SLLNVGMRVRKSVPEGYKTHKtvppaa-----avsapYKAQAAFVPAS-------------------------------- 96 
Q7SI33        64 SLLNVGMRVRKSVPEGYKTGKi---------------ASGFPSWMDDSNNTNNRNHISGSgasalagnnghn----rpvs 124 Neurospora crassa
XP_003352469  65 SLLNVGMRVRKSVPEGYKTGKi---------------ASGFPSWMDESSNSNNTSSAGASasfagnnnghnrpvsalpps 129
Q6CD17        38 QLASVGMGIRKSVSDGHKTTGnh------------naSLRHESFTPVADVQNPLRGTYGPasslggyitks-------fs 98  Yarrowia lipoly...
CCE82863      25 SLATVGMRVRKAVAEGYNVPD----------------------------------------------------------- 45 
Q6BME9        25 SLSTLGMRIRKSVADGYNVPS----------------------------------------------------------- 45  Debaryomyces ha...
EPE07517     111 -agrpaapPTPSQRELLPFCG--LNKVG----GLDVQsygdedGRPmfas-slfeEMDDGATAVASDSEPPA----LT-- 176
EMD94723     123 --------HYQHQRELLPFCG--LYNIG----GFAEQpttnphLYTtsp---trqRPAIAFPLTADAFTQPF-------- 177
CBX99698     251 --------RLTHQRELLPFCG--LNKIA----GYAEQpttnrhLYGgghd-satqESTNLFPLSAEAFTQPF-------- 307
EKG12242     103 --------AAARPAELLPFCG--LQKTG----GYTVQgptpapYAY---------------DAGAAAIPVDAhgiaFAae 153
XP_007585271  97 --------AASRPTELLPFCG--LHKTG----GYVAQqpttapYIH-----------DAGSAAATAHNPVDAhgihFSad 151
Q7SI33       125 aapsappaAASANRELTPFCG--IHKIG----GYAVQ------------------------------DSNNNnnsaAL-- 166 Neurospora crassa
XP_003352469 130 apvtatsaSASANRELTPFCG--IHKTG----GYAVQ----------------------------------EdnksAL-- 167
Q6CD17        99 aapelglgSANKDREVKGYKG-----IG---------------------------------------------------- 121 Yarrowia lipoly...
CCE82863      46 -------------RDRYDISGfsQNGMDyarnDVGQHtaeennSTG---------FRVPQRVPLPAHMDGPPglsdSLst 103
Q6BME9        46 -------------NKYNGYNA--YDRMGytshGEYGRvepkaiGIFggnqdgsniDYEPARVPLPTHMSQPPaltnVGst 110 Debaryomyces ha...
EPE07517     177 ----SSQETV 182
EMD94723     178 ----PDQSSA 183
CBX99698     308 ----SSQGST 313
EKG12242     154 nfglSSQESN 163
XP_007585271 152 nfafSSQESN 161
Q7SI33       167 ----SSQDSN 172 Neurospora crassa
XP_003352469 168 ----SSQDSN 173
Q6CD17       122 ----AERYSL 127 Yarrowia lipolytica
CCE82863     104 aessSNLSDW 113
Q6BME9       111 igtcSNLSEW 120 Debaryomyces hansenii
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