3BFV,3CIO,3LA6,4JMP,2VED,4JLV


Conserved Protein Domain Family
BY-kinase

?
cd05387: BY-kinase 
Click on image for an interactive view with Cn3D
bacterial tyrosine-kinase
Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.
Statistics
?
PSSM-Id: 349772
Aligned: 67 rows
Threshold Bit Score: 109.582
Created: 28-Aug-2007
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
 
active siteoligomer
Conserved site includes 11 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Structure:3BFV; Staphylococcus aureus CapB with bound MgADP, contacts at 4A

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                      ######                      #    #                
3BFV_A        64 EKFRGIRSNIMFANpdsavQSIVITSEa-PGAGKSTIAANLAVAYAqa-gyKTLIVDGDMRKPTqhyifn---------- 131 Staphylococcus ...
NP_418983    524 ESLRKLRASILFSKvgetvQVIAVTSSl-PGEGKTTTTFSLARTLAts-gaKVIVVDCDLRQSAisqflk---------- 591 Caulobacter cre...
AEB07283     258 ESARTVLANLAFLKigdpiRSITVTSAa-DQEGSPDVALLVAKAAAsd-grKVLLVECDFRNRPlfdlig---------- 325 Coriobacterium ...
ADY66130     491 SAFADLQTHIQLAEsk--aKVIAFTSSa-DGEGKTFVIANLARSLAms-gvKLLLIDANLRNPAlgsefd---------- 556 Agrobacterium s...
CAJ73300     356 SSYHDLSDQIYLLMkdkklKALLITAVs-HLEGSTTIVANIGLSLAre-ghKVLVIDANLKSPEihemfk---------- 423 Candidatus Kuen...
AEA70102      14 SETNLTSTVLDPSL-----RILLLTAAn-TGTGTSTSAMALAAQLAqmsngRVLLVDASQSPRNlsqqls---------- 77  Pseudomonas bra...
NP_437284    408 EAERAVYMAGRYSDakqlrRIVMVTSCv-HNIANASTAWGIATAAAad-grPTAFVNLDFNRHNvpylks---------i 476 Sinorhizobium m...
ADY20961      19 EQFYTLYHELKKSGk----QVFTISSTk-DRGVVASFIVNIGLVFAem-kkKVLLIDVNFSDPKlhlllq---------- 82  Bacillus thurin...
ADW02803     311 EEYRAVAFRLAYDPsfaerRRLLVTAPrgDNAAASAAAVNLAAAFAem-grDVLLVEADLRTPSlardlgpaahevrpps 389 Streptomyces fl...
YP_001637320 310 NAVKEAHTQIVLAGlprnaRILMVSGPr-PSNERSALAVDLAHCYTls-gyRVLLVDAETERAIlseff----------- 376 Chloroflexus au...
Feature 1                                                                                #       
3BFV_A       132 lpnneGLSSLLLNwst----yqDSIISTEIe-dLDVLTSGpippNPSELITSRAFANLYDTLLMn-YNFVIIDTPPVNTV 205 Staphylococcus ...
NP_418983    592 epapvGLLEVLNGvat----ldQAIINDESg--AHILPLAkssyTPRDVLGSSAMHRLLGELRGr-YEIVLLDTAPLLAI 664 Caulobacter cre...
AEB07283     326 ahsreGLRSVLSQccs----lvQAVCDIGHe-nVFFLDAEtgvpNPTELISSERFKALHDILSEh-FSYIVYNAPRLGPF 399 Coriobacterium ...
ADY66130     557 vgsasHVAQAVNRevs----ldDIIQCDQAs-gVDIIIAEksdlPPNLVLGSKRFAALFAEARQr-YELVLIDAPSIAYD 630 Agrobacterium s...
CAJ73300     424 ipnnsGLTHVLEGkia----leEAIKEIDCn--LSVLTAGnttlNPTLLFDSTRMANTIKEAKGk-YGFVFVDYANLRNS 496 Candidatus Kuen...
AEA70102      78 lhkerGFTDLLFNslappllqdCVVQASSLp--FDVLPHGrl-gRNAERLSPERLRPLFRQLAAq-YRFVVIDADAVYSA 153 Pseudomonas bra...
NP_437284    477 erspePIERYLRNqav----igEIVQSIPTlpgFGFIDAShvmmEPFRSLDSDKLCELIMDLKQsgYDFIVLHAPPVLAS 552 Sinorhizobium m...
ADY20961      83 snhtkTVNDIISDpsc----syETFSSNLSk-yLYCIPAKktvhTGTPLVATDEFDDVIAKWKEd-FDYIFLYSSEVFEL 156 Bacillus thurin...
ADW02803     390 waaeeGDRTWPAGg-------rCNVDVPGSg--AFALVAGttadNVPRALTSASVARIVAEADRp-GAVVIVLAPPVLSY 459 Streptomyces fl...
YP_001637320 377 -adpnAVLQPISIdgea--qvwSSLRVTPIk-nVLLLARNtd-dQGRPLPPSQPWPALVDGLQRa-ADILIFDGPSTLSG 450 Chloroflexus au...
Feature 1                                                       ##
3BFV_A       206 TDAQLFSKftGNVVYVVNSENNNkDEVKKGKELIEATgak-llGVVLNR 253 Staphylococcus aureus
NP_418983    665 ADTRILAPhtDAVVMLVRWKKTPvKAVQSALALLQGTraf-iaGVALTQ 712 Caulobacter crescentus CB15
AEB07283     400 ADAAILSAlsDAALLVVRNGVTRaGELEKGSGQLRKAgpp-vaGIAYNR 447 Coriobacterium glomerans PW2
ADY66130     631 LDLLRIATlsDAVSFVVRQEVADgTGMKNAVLKLRVAgrp-itGIILNG 678 Agrobacterium sp. H13-3
CAJ73300     497 HDADILSSslDGTVLVVNESKTKhHVIKALIAPLVQKkan-iiGVILNN 544 Candidatus Kuenenia stuttgartiensis
AEA70102     154 SDTLVLSTqvDGVVLVVRGEDTRwEVAQAARQRLSQAgak-vvGSVFNR 201 Pseudomonas brassicacearum subsp. brassicacear...
NP_437284    553 GDATWLAPfvDGVVLIANWGKTTeEQLLEAAAQLRMNhah-liGTVINQ 600 Sinorhizobium meliloti 1021
ADY20961     157 PATHMIAGkcDGVVLAVKKRKDSlRTVQKVIANIKKKece-liGIVLYS 204 Bacillus thuringiensis serovar finitimus YBT-020
ADW02803     460 ADAVALVDrvEGVMIVCDPREVHrSDLERIREIISASggq-vlGALLHT 507 Streptomyces flavogriseus ATCC 33331
YP_001637320 451 VEAALLAPmmDGVILALKPVEDSsRDIQQSLKRLTLKrtdsvlGAVMLT 499 Chloroflexus aurantiacus J-10-fl

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap