Conserved Protein Domain Family
R_switched_YkoY
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TIGR03716: R_switched_YkoY 
integral membrane protein, YkoY family
Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains proteins YceF and YkoY from Bacillus subtilis. A transport function is proposed.
Links
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Statistics
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PSSM-Id: 274742
Aligned: 20 rows
Threshold Bit Score: 212.519
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_011067432  17 IGLEGLLAADNALVLAIMVRHLPE-K-QRK-RALFYGLAGAFVFRFASLFVISFLVDFWQVQALGAAYLLFISLKNLYDR 93  Oceanobacillus ...
WP_010964724  37 IILEGLLSSDNAVVLAIMVKHLPK-K-QQK-RALFYGIWGAYIFRFIAIGVGTYLIKIWWVKLIAALYLLKMTYSHFAGK 113 Clostridium ace...
WP_011140629  27 VFVEGALSADNAAVLAALTRTLPTdE-ERR-RSLRYGIIGAFVFRFFAVLFAAWLIDNWPLKLAGALYLIYLAVSHFLKG 104 Gloeobacter vio...
WP_011342565  28 AILEGILSVDNALVLAILVRNLPR-Q-QQK-RALTYGIIGAFVFRFIALVFAAHLMRFGFFKLIGGGYLIYLAMKHMFFF 104 Pelobacter carb...
WP_003246458  37 VVLEGLLSADNALVLAVMVKHLPE-K-QRK-KALTYGLFGAYIFRFIFIGLGMLLIKFWWIKVLGALYLAWLVIKHFWIG 113 Bacillus subtilis
WP_021741549  31 VLIECLLSVDNAVVLAAQTQSLPT-ReQQE-KSLFYGIWGAYFFRFVIIGLGTYLIHFWEIKVIGALYLLYLVFQFFTRT 108 Lactobacillus b...
WP_011375329  34 VIMECLLSVDNAVVLAAQTQSLPT-KiEQE-KSLVYGLWGAYLFRFIIIGVGTFLIHLWEIKVAGSLYLVYLVYAYFRKQ 111 Lactobacillus s...
WP_000025696  37 VVLEGLLSADNALVLAVMVKHLPE-E-KRK-KALFYGLIGAYVFRFIAIGIGMFLIKLAWVKVLGALYLAWLSVKYFIDK 113 Bacillus cereus...
WP_011430389  32 VFLEAALSADNAVALAALVKHLPT-P-QQQnRALRWGIIGAYGFRIAIVFAAVWLVEYPPAQFLGACYLLWLAWQHFRGE 109 Synechococcus s...
WP_021721633  28 IIMECLLSVDNAVVLAAQTQVLPT-KsEKE-KSLLYGLWGAYLFRFIVIGIGTYLINFWEIKLAGSIYLFYLSIKFFYDQ 105 Lactobacillus a...

WP_011067432  94 FKKKKEPEE-----DLEIaedakesvaalankepeqasK-----------KE------------FWLTVVKVEFADLAFA 145 Oceanobacillus ...
WP_010964724 114 AEDDDVDES-----KVSK--------------------------------KG------------FWATVATVELMDIAFS 144 Clostridium ace...
WP_011140629 105 KDEDEDVVA-----EEKKl-------------------L-----------SNplfratlgrlspFWRVIVLVELTDIAFS 149 Gloeobacter vio...
WP_011342565 105 YKEDAHQLR-----DKPAa--------------------------------G------------FWKIVIMVELTDIAFS 135 Pelobacter carb...
WP_003246458 114 EKEEEADGM-----KKNSwmv---------------rtF-----------GI------------FWATVISVELMDLAFS 150 Bacillus subtilis
WP_021741549 109 RVKHTRKLA-----SEKKh-------------------Rw---------lPL------------FWAVVLQIEMMDIIFS 143 Lactobacillus b...
WP_011375329 112 KQPKQVKKP-----GSKIs------------------sP-----------HR------------FWRTVISIELMDIVFS 145 Lactobacillus s...
WP_000025696 114 RKGNAEEEE-----AHGMn-------------------Qnsil---frmfGV------------FWGTVAMVELMDIAFS 154 Bacillus cereus...
WP_011430389 110 EEGPEQDIT-----RQ----------------------------------AN------------FWQTLVMVELTDLVFS 138 Synechococcus s...
WP_021721633 106 RHPKEVVEHekekeAREKa-------------------HyknkkkkkhvlSL------------FWRTVISIESMDIVFS 154 Lactobacillus a...

WP_011067432 146 VDSILAAVALavalpatglgnigsldTGQFMVVFAGGMIGLIIMRFAANIFVEVLHKRPALEVAAFLIVGWVGVKLAVLV 225 Oceanobacillus ...
WP_010964724 145 IDSVSAAFGV----------------SSKVWVLFLGAVFGILAMRGVAQIFVALIEKVPEMESSAYVLIGIIGIKMLL-- 206 Clostridium ace...
WP_011140629 150 VDSITAAVAF----------------SDKAWVVIVGGILGIVTMRFVAELFIKLIDRYVRLETAAFLAVGFIGFKMMTEV 213 Gloeobacter vio...
WP_011342565 136 IDSITTAVAM----------------TDKLLVVWVGGILGIIFLRFAASFFVRLLERLPRLEDLAYQLIFFIGTKLFL-- 197 Pelobacter carb...
WP_003246458 151 VDSILAAFAV----------------SEKVWVLLIGGMLGILMMRTVAKVFLVLIDKIPELENTAFVLIGIIALKMAG-- 212 Bacillus subtilis
WP_021741549 144 VDSVLASLAI----------------SSNPVIVLIGGLIGILAMRGVAEVIMRLMQKIPELEPMAYILIALIAVKLFI-- 205 Lactobacillus b...
WP_011375329 146 IDSVLASLAI----------------SSNPVIVLIGGMIGIICMRGIAQIIARLMEKIPELNPMAYILILFIAVKLFL-- 207 Lactobacillus s...
WP_000025696 155 VDSVLAAFGV----------------SNEVWILLLGGMLGILMMRGIAGVFLKLLERIPELETTAYILILIIAAKMLL-- 216 Bacillus cereus...
WP_011430389 139 FDSIAASVGV----------------SRKAWVIILGGILGITLMRYMASLFLRWLDEFSRLEDAAFAIIALVGSLMLLE- 201 Synechococcus s...
WP_021721633 155 IDSVLAALAI----------------SDNPVVVLIGGMIGILCMRGVAEIIIKLMDIIPELEPMAYVLIG------IIAL 212 Lactobacillus a...

WP_011067432 226 MANPDIGWLSEHFPHSTGWKVSFYIILVAIAVV-GWFASSPK 266 Oceanobacillus iheyensis
WP_010964724 207 ------NLINIEIPNT-----IFFGVIVVVFGG-TIAFHYIR 236 Clostridium acetobutylicum
WP_011140629 214 VANQLLPKLHFETPE--------WVVLGVVAAIfAWGFTKKN 247 Gloeobacter violaceus
WP_011342565 198 ------DGFHVEISHG-----IFWLMMGIIAVL-GASLVYRD 227 Pelobacter carbinolicus
WP_003246458 213 ------SAFHYEMPHSVFFIII-----IAAFAV-TLIIHYIN 242 Bacillus subtilis
WP_021741549 206 ----SIPAIDIEIPAT-----LFGLLVVGAIIV-TLIIHVIR 237 Lactobacillus brevis
WP_011375329 208 ----SIPAIDIEIPN-----LVFAGIVFGTILI-TLGIHYIR 239 Lactobacillus sakei
WP_000025696 217 ------SVIHIEVSHT-----LFFIILVVAFGA-TFILHYVK 246 Bacillus cereus group
WP_011430389 202 -----VFFPQIELPE--------WGMVLAVLPLfVWGFSQRR 230 Synechococcus sp. JA-3-3Ab
WP_021721633 213 KLLLALPPLKWEMPNTA-----FAIIVFAILGL-TIIFHFWR 248 Lactobacillus acidophilus
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