Conserved Protein Domain Family
PRK11519

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PRK11519: PRK11519 
tyrosine-protein kinase Wzc
Statistics
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PSSM-Id: 183173
Aligned: 62 rows
Threshold Bit Score: 1225.01
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
261822280   1 MTEKTSVKVSE-THSDEIDLGRLLGTLLDNRWLIIGVTAVFTVLGIIYAMLATPVYKADALIQVEQSSGNSLLNDISSML 79 
146312317   1 MTEKTKPSAAPiSGSDEIDIGRLVGTVVEAKWWVLGITAVFALAAVIYTLFATPIYSADALVQIEQNSGNSLVQDIGSAL 80 
296103720   1 MTEKTKPSAAPiSGSDEIDIGRLVGTVIEAKWWVLGITAVFAAAAIVYTLFATPIYSADALVQIEQNTGNSLVQDIGSAL 80 
161502732   1 MTEKVKQSAAa-TGSDEIDIGRLVGTVIEARWWVLGTTAIFALCAVIYTLFATPIYSADALVQIEQNTGNSLVQDINSAL 79 
194736839   1 MTEKVKQSAAv-TGSDEIDIGRLVGTVIEARWWVLGTTAIFALCAVIYTFFATPIYSADALVQIEQNAGNSLVQDINSAL 79 
85058958    1 --MNKNNLFVAkEDSNEVDLGRIFGSIIDYKWLIFSITSLAAILGILYTLFATPIYQADALVQVESTTGSQIIQNMNSLS 78 
50120358    1 MAEKISVKTAD-TNADEIDLGRLLGTLLDNRWLIIGVTAIFLIFGILYATLATPIYKADALVQVEKNSSNKLINDITSML 79 
253687691   1 MAEKISVKASE-TNTDEIDLGRLLGTLLDNRWLIIGVTAVFTIFGILYATFATPIYKADALIQVEQSSGNSLLKDISSVL 79 
271499801   1 MSERIAVKTAEaDKADEIDLGRLLGTVLDHRWLIISITTIFTMLGILYALLATPVYQADAMVQVEQNVSDSLMSDISKVL 80 
260598549  13 MTDKVRHSAAPvEGGDEIDIGRLVGTVVEARWWVLGITALFALGALIYVMFATPIYSADALVQIEQNQGNSLVQDISTAL 92 
261822280  80 PDAKPQSAAEVELIKSRMVIGKTVNDLVLDINVQQKYFPLVGKGLARLAGNEPGKIAVSRLDVPASWQDETLLLEVLPNQ 159
146312317  81 ANKPPASDAEIQLIQSRLVLGKTVDDLDLDIGVTKDTFPIFGAGWDRLMGRQNDMVKVTTFELPKGAGDQVFTLEVLGPK 160
296103720  81 ANKPPASEAEIQLIQSRLVLGKTVHDLGLDISVTKNTFPIFGAGWDRLTGHSNDTVKVTDFVLPKGSADQTFTLTVLGPK 160
161502732  80 ANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVTKNTFPLFGAGWDRLMGHQNETVKVTTFTRPEAMSGQIFTLKALDDK 159
194736839  80 ANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVTKNTFPLFGAGWERLMGRHNERVKVTTFTRPETMSGQIFTLKVLGDK 159
85058958   79 LEAKPVSMTEIELIESRMVLGKTVDDLGLDVTLQQKYFPVLGKGWARLTGKEAGRIALSRLRLPSDMYNVPMTLIITDKQ 158
50120358   80 PDAKPESAAEVELITSRMIIGKTVNDLALDINVQQNYFPFFGKGIARLTGATKGVLAVSRLEVPDSWKDEPIILTVTDNK 159
253687691  80 PDAKPESAAEIELIKSRMVVGKTVKDLSLDIVVQQKYFPIFGKGFARLMDDEPGKIAVSRLEVPQSWQEKLIKLTVLDLQ 159
271499801  81 PDTKPQSAPEVELLRSRMVVGKTVQDLGLDTDVEQQYFPLFGKGLARLKDEEPARVVVSRLSVPDSWLDEKMTLAIGENG 160
260598549  93 QNKPPASDAEIQLIQSRLVLGKTVDDLDLDIAVQKKTFPLFGSGWERLMGRADETIKVTTFELPKGMAEDEFTVAVLGPK 172
261822280 160 QYAVEAGDV-VKFTGTIGQLENHNGITLLVSDIVAEPGTIFRIQKLNQLTAINDLLENFTVADKGKDTGVLALSLEGEAP 238
146312317 161 QYQLTSDAG-FSARGEVGQMLTKNGVTMMVSDIKAAEGGKFTVSKFSMLGMINNLQGNLTVTENGKDTGVLSMTFTGEDK 239
296103720 161 QYQLTSDAG-FSARGEVGQMLTKDGVSMKVSAIQAQEGSEFTVTKFSTLGMINNLQNNLTVTENGKDTGVLSMTFTGEDK 239
161502732 160 RYQLVSDGG-FSVQGVVGKTLNKGGVTMRVEAIDARPDTEFTVSKFSTLGMINNLQNNLTVTETGKDTGVLSLTFTGEDR 238
194736839 160 RYQLVSDGG-FSAQGVVGQPLNKDGVTMWVEAIDARPDTEFTVSKFSTLGMINNLQNNLTVTETGKDTGVLSLTFTGEDR 238
85058958  159 HYQLKNDDGeVLVEGQVGQLASKGDFGLLISGIETEPGTEFEVVKHPTLGAINNIANNLLVEDKGKDTGVLSMTYTGPDK 238
50120358  160 NYSISAGDA-VRFEGQVGRLERHDGMTLLISDIAADEGTTFSIKKLNQLTAINNILKTLTVADRGKDTGVLALSLEGEDP 238
253687691 160 TYQVEVGDV-VKFKGKVGQIEKHDGLSILLSEIQAEPGMVFRVQKLNTLTAINNVLGNLSVADKGKDTGVLSLSFEGEEA 238
271499801 161 TYRFSAGKD-ADFTGHIGQVASQHGFSLLVSSTDAAPGTVFTVRKKNTLTAINDILAELSVADKGKDTGVLQLTLEGSDP 239
260598549 173 QYQLTSSGG-FSARGEVGKPLSKDGVKMMVDQIHAQEGSEFTVTKYSTLGMINQLQNNLTVTETGKDTGVLSLTYMGEDR 251
261822280 239 VLTTKILSSISQNYLQQNVERKSEEAGKSLEFLKEQLPNVRSSLNDAENKLNQFRQQNESVDLSLEAKAVLDTTVAVEAQ 318
146312317 240 DKIRDILNSITRNYLEQNVERKSAEAAKSLAFLAKQLPEVRAHLDEAENKLNAYRQDKDSVDLPLEAKSVLDSMVNIDAQ 319
296103720 240 DQIREILNSITRNYLEQNVERKSAEAAKSLAFLARQLPEVRARLDDAENKLNAFRQDKDSVDLPLEAKSVLDSMVNIDAQ 319
161502732 239 DQIRDILNSITRNYLEQDIARKSEEAGKSLAFLAKQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQ 318
194736839 239 DQIREILNSITRNYLQQDIARKSEEAGKSLAFLAKQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQ 318
85058958  239 ELIRKTLDSITQNYLLQNIERKSAEAEKSLNFLQTQIPKVRATLDDAENKLNTFRQQNDSVDLSLEARSVLDSLFNIDAQ 318
50120358  239 ILTNKILNSISENYLQQNVERKSEESGRSLEFLKEQLPNVRSILDEADNKLNIFRQKNESVDLSLEAKSVLETMVALEAQ 318
253687691 239 ELTNKILNSISQNYLQQNVERKSEEAGKSLEFLKEQLPSVRLNLDDADNKLNSYRQKNESVDLSLEAKAVLDTMVAVESQ 318
271499801 240 ALVKKTLTSISDNYLQQNVDRKSEEAARSLAFLKEQLPLVRASLETAEDKLNKYRQQKDSVDLSLEAKSVLDTIVDVESQ 319
260598549 252 DQIRDILNSITRNYLEQNIERKSEEAAKSLAFLAKQLPEVRSNLDIAENKLNAYRQQQDSVDLPLEAKAVLDSMVNIDAQ 331
261822280 319 LNELTFKEAEISKLYTREHPAYRALMEKRKTLQQERDKLNKRVGAMPKTQQEILRLTRDVQAGQEVYMQLLNKQQELNIN 398
146312317 320 LNELTFKEAEISKLYTKRHPAYRTLLEKRQALEDEKSKLNNRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKIT 399
296103720 320 LNELTFKEAEISKLYTKRHPAYRTLLEKRRTLEEEKAKLNDRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKIT 399
161502732 319 LNELTFKEAEISKLFTKAHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKIT 398
194736839 319 LNELTFKEAEISKLFTKAHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKIT 398
85058958  319 LNQLTFKEAEISKLYTKEHPAYRTLLENRKTLENEKAELSKQVSALPKTQQEILRLTRDVDANQAIYMQLLNRQQELNIT 398
50120358  319 LNELTFKEAEISKLYTKEHPAYRALLEKRKTLEEEKEKINKRVGAMPKTQQEIIRLTRDVKAGQEVYMQLLNKQQELSIN 398
253687691 319 LNELTFKEAEISKLYTKEHPAYRALMEKRKTLEEEREKINKRVGVMPKTQQEILRLTRDVNVGQEVYMQLLNKQQELSIN 398
271499801 320 LNQLTFREAEISKLYTREHPAYRALLEKRVTLEKERDSLNRRVSSMPKTQQEIVRLTRDVNVGQEVYVQLMNKQQELSIN 399
260598549 332 LNELTFKEAEISKLYTKAHPAYRTLLEKRQALEDEKAKLNNRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKIT 411
261822280 399 KASTVGNVRIIDNSVIQPKPVKPKKTLIVLIAMILGGTISTAFVILKTLLHKGIESPEQLEELGINVYASVPLSEWQQKK 478
146312317 400 EASTVGDVRIVDPAITQPGVLKPKKALIVLGSIILGLMLSIMGVLLRSLFNRGIESPQVLEENGISVYASIPLSEWQKSR 479
296103720 400 EASTVGDVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNRGIESPQVLEENGINVYASIPLSEWQKSH 479
161502732 399 EASTVGDVRIVDPAITQPGVLKPKKALIILGSIILGLLLSVIGVLLRSLFNRGIESPQALEEHGISVYASIPLSEWQKAR 478
194736839 399 EASTVGDVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLSEWQKAR 478
85058958  399 RASTVGNVRIVDPAVTLPEQIAPKSALIILGSVVVGLVLSLIFIILRTILHRGVESPAELEEAGINVYASVPLSEWQQKV 478
50120358  399 KASTVGNVRIIDSAVVQLRPVKPEKVFIVLLSIILGGLLSVSFVLIRTILHKGIESPEQLAELGISVYASVPLSAWQQKK 478
253687691 399 KASTVGNVRIIDPSAIQLSPVKPKKALIVLLAILLGGMVSTAFVVLKTLLHKGIESPEQLEELGINVYASVPLSEWQQKK 478
271499801 400 KASTVGNVRIIDPAVVQLKPVKPKKTLVIVLAAMLGGVAAIGFVLLKTLLHRGIESPEQLEELGINVYASVPLSEWQQKK 479
260598549 412 EASTVGDVRIVDPAITQPGVVKPKKALIVLGSIILGLLLSIVIVLLRSLFNRGIESPLALEEAGINVYASIPLSEWQKSR 491
261822280 479 DRALLGKKnkKGNTRATDLLAVGNPADLAIEAIRSLRTSLHFAMMEAKNNVLMISGASPAIGKTFVSANLGAVIAQSGQR 558
146312317 480 DSVKTVKG--IKRYKQSQLLAVGNPTDLAIEAVRSLRTSLHFAMMQAKNNVLMMTGVSPSIGKTFVCANLAAVVSQTNKR 557
296103720 480 DRVKSVKG--VKRYKQSQLLAVGNPTDLAIEAVRSLRTSLHFAMMQAKNNVLMLTGVSPSIGKTFVCANLAAVVSQTNKR 557
161502732 479 DSVKTIKG--IKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMLTGISPSIGKTFVCANLAAVISQTHKR 556
194736839 479 DSVKTIKG--IKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMLTGVSPSIGKTFVCANLAAVISQTHKR 556
85058958  479 DREFKSGS--KKRHRET-LLALNNLSDPAIEAVRSLRTSLHFAMLEARNNILMISGASPSIGKTFISSNLAALIAQAGQR 555
50120358  479 DRALLGKGk-RGNTRSTELLAVGNPADLAIEAIRSLRTSLHFAMMEAKNNVLMISGASPAIGKTFVSANLGAVIAQSGQR 557
253687691 479 DRVLLARSn-KSNTRATELLAIGNPTDLAIEAIRSLRTSLHFAMMEAKNNVLMISGASPAIGKTFISANLGAVISQSGQR 557
271499801 480 DREFAGKNr-KRNARSDSLLAVGNPADLAIEAIRSLRTSLHFAMMEAKNNVLMISGASPGIGKSFISANLGAVIAQAGQR 558
260598549 492 DSVKTVKG--VKRFKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAPNNVLMLTGVSPSIGKTFVCANLAAVISQTHKR 569
261822280 559 VLIVDCDMRKGYAHELMGTHGADGLSDILSGQCKAEKSVRKTAVENMDFIPRGQVPPNPSELLMHSRFTEFLKWAGEHYD 638
146312317 558 VLLIDCDMRKGYTHELLGTNNVNGLSEILLGKGEIEQCAKPTSITNFDLVPRGQVPPNPSELLMSERFTQLIEWASKHYD 637
296103720 558 VLLIDCDMRKGYTHELLGTNNVNGLSEILLGKGEISQSAKPTSIPKFDLIPRGQVPPNPSELLMSDRFAELVEWASKNYD 637
161502732 557 VLLIDCDMRKGYTHELLGTNNVDGLSDILAGKGEMTSCAKSTAIPNFDLIPRGQVPPNPSELLMSERFGELIAWASSRYD 636
194736839 557 VLLIDCDMRKGYTHELLGTNNVDGLSDILAGKGEIASCAKPTAIANFDLIPRGQVPPNPSELLMSERFGELITWASSRYD 636
85058958  556 VLLIDGDLRKGYVHEMLGLNNQKGLTELLSNQTTLEVSIQNSGVSNFDIITRGQVPPNPSELLMGNILEEILAKVSTLYD 635
50120358  558 VLIVDCDMRKGYAHELMGCQGTDGLSDILSGQITTDKSIRKTAVENMDFIPRGQIPPNPSELLMHSRFSQFIDWATKNYD 637
253687691 558 VLIVDCDMRKGYAHELMGTQSVDGLSDILSGQIEVEKSIRKTALENMDFIPRGQIPPNPSELLMHSRFPQFIKWAAEHYD 637
271499801 559 VLIVDCDMRKGYAHHLLGATPERGLSDILSGQIEAQQALRTTVVENLFFIPRGQIPPNPSELLMHSHFTDFINWATGQFD 638
260598549 570 VLLIDCDMRKGYTHELLGTTNVNGLSDVLAGQGDISRCAQKTSVPGFDLVPRGQVPPNPSELLMSERFAELVKWASANYD 649
261822280 639 LVLLDTPPILAVTDAAIISRHAGTSLLVARFEMNTLKEIEVSIRRFEQNGAEIKGVILNAIMKRAAS-YYGYGnydY--Y 715
146312317 638 LVLIDTPPILAVTDAAVVGRHAGTTLMVARYAVNTLKEVETSLNRFEQNGIDVKGVILNSIFRRATG-YQDYG---Y--Y 711
296103720 638 LVLIDTPPILAVTDAAVVGRLAGTTLMVARYAVNTLKEVETSLSRFEQNGIEVKGVILNSIFRRATG-YQDYG---Y--Y 711
161502732 637 LVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIQVKGVILNSIFRRATG-YQDYG---Y--Y 710
194736839 637 LVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFDQNGIQVKGVILNSIFRRATG-YQDYG---Y--Y 710
85058958  636 MVLIDTPPILAVTDAAVIGHHVGTSLLVARYGINTLKEIEISINRFAQNGTEVKGVILNSVFKHARNvYSSYG---Y--- 709
50120358  638 IVLLDTPPILAVTDAAVISRHAGTSLLVARFEVNTLKEIEVSIRRFEQNGTEIKGVILNAIVKRAAS-YYSYGnydY--Y 714
253687691 638 IVLLDTPPILAVTDAAIISRHAGTSLLVARFEVNTLKEIEVSIRRFEQNGAEIKGVILNAIVKRAAS-YYGYGnyhY--Y 714
271499801 639 IVLLDTPPILAVTDAAIISRQAGTSLLVARFETNTPKEVEISIRRFEQNGAPIKGVILNAVIRRALS-YYSYG---YdsY 714
260598549 650 MVLIDTPPILAVTDAAVVGRHAGTTLMVARYAVNTLKEVQTSLSRFEQNGIEVRGVILNSIFRRASG-YQDYG---Y--Y 723
261822280 716 TYEYKSKS 723
146312317 712 EYEYKSDS 719
296103720 712 EYEYKSDS 719
161502732 711 EYEYQSDA 718
194736839 711 EYEYQSDS 718
85058958  710 -YEYKSDN 716
50120358  715 SYEYKSDK 722
253687691 715 TYDYKSEK 722
271499801 715 QYSYGSDK 722
260598549 724 EYEYKSDH 731
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