3NKD


Conserved Protein Domain Family
cas1_ECOLI

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TIGR03638: cas1_ECOLI 
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CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI
The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.
Statistics
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PSSM-Id: 274693
Aligned: 17 rows
Threshold Bit Score: 335.401
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3NKD_A         6 LNPIP-LKDRVSMIFLQYGQIDVIDGAFVL-IDKTGi---RTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGE 80  Escherichia col...
WP_000144847   6 LSPIP-LKDRTSMIFLQYGQIDVLDGAFVL-IDKTGi---RTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGE 80  Escherichia coli
WP_011387928   9 LRPIA-IKDRSSIVFLQRGQLDVVDGAFVL-IDQEGv---RVQIPVGGLACLMLEPGTRITHAAIVLCARVGCLVIWVGE 83  Rhodospirillum ...
WP_011448384   8 IKPIP-IKERSSVVFLGRGELDVIDGAFVL-VDTNGi---RMQIPVGGLASLMLEPGSRVSHAAVSLASKVGCLLVFVGE 82  Methanospirillu...
WP_010933633  21 RETLPqVKEKYPFLYLEKGRIEIDDSSIKW-IDCDCn---VVRLPVAMLNCILLGPGTTVTHEAVKVMAAANCGICWVGD 96  Chlorobaculum t...
WP_003619879  12 LTELGrTEDRITFLYIEHAKLYRKDGAVEV-RDEEG----IVYVPAAIISVLLLGPGVDVTHRAMELMGDSGMAVVWVGE 86  Lactobacillus d...
WP_011601714   7 PLDLHrIEDRVSSLYVEKCHIDRDDNAVVL-INRER----TVRVPAAFVATLLIGPGTRVTHAAVRLLADSGTAVCWVGD 81  Frankia alni
WP_011273274  12 RPILPrVQDRISFLYAERCVVNRDNNAVTF-ADERG----ITHVPAASIAALLLGPGTKVTYAAMALLGDSGVSVVWVGE 86  Corynebacterium...
WP_011458705  11 apvrmaHKNRIPYLFLEKGILRVDGHCLLL-CQAES----AIEIPGSMVSCLMIEPGVSVTHEAMKLCGENGTLLMWVGE 85  Albidiferax fer...
WP_011292015  13 LAMLPrVSDGLSFLYVDVCRIVQTDTGVCAeVETETgrihRVPIPTASLACVLLGPGTSITSPAMATFMRHNTTVVTCGA 92  Thermobifida fusca
3NKD_A        81 AGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPApARRSVEQLRGIEGSRVRATYALLAKQYGVTW 160 Escherichia col...
WP_000144847  81 AGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPpARRSVDQLRGIEGSRVRQTYALLAKQYGVKW 160 Escherichia coli
WP_011387928  84 RGTRLYAAGQPGGARADRLLFQARNALDETARLNVVREMYRRRFDDDPpARRSVDQLRGMEGVRVREIYRLLAKKYAVDW 163 Rhodospirillum ...
WP_011448384  83 GGVRLYSVGHPGGARSDRLLYQARLALDEVLRLKVVKKMFSLRFGEDFsDAYSVEQLRGLEGVRVREGYRKIARDTGVIW 162 Methanospirillu...
WP_010933633  97 DSLMFYASGQTPTSNTRNMTHQMKLAANPAKALEVARRLFAYRFPDANlENKTLPQMMGMEGLRVRKLYEEMAVKYKVGW 176 Chlorobaculum t...
WP_003619879  87 QGVRQYAHGRALNRSSRLLEAQAKLVSNVRSRVAVARKMYQLRFPDEDvTKLTMEEMRGKEGTRVRRVYREQAKKTGVKW 166 Lactobacillus d...
WP_011601714  82 RGVRMYAGGLGPSRGSGLLMRQAYLVTRTQHRLAVARRMYGMRFPDDDvSTATMQQLRGREGARIKKVYRAHAERTGVSW 161 Frankia alni
WP_011273274  87 KGVRYYASGRSLSNSSAAAEAQASIVSNQRRRLFCARQMYAMRFPGEDiSRATMAQLRGREGSRMKKVYLAEAERTGVPW 166 Corynebacterium...
WP_011458705  86 GGTRFYAAAHA-HQDASRVLRQAAIHTNQRERIAAASRLYGLMFDDHMpPSFTIEKLRGLEGSRVKEIYVNLADKLGMVW 164 Albidiferax fer...
WP_011292015  93 GGILNYGSFPAPNRTTKWIDRQARAYSDDRRRRDVAVRMYEMRFGEEPpPGASIERLRQLEGARMKALYRSLAAKNRVKP 172 Thermobifida fusca
3NKD_A       161 NGRRYDPKD-WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR- 238 Escherichia col...
WP_000144847 161 NGRKYDPKD-WEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAAR- 238 Escherichia coli
WP_011387928 164 NARRYDHND-WDGADIPNRCLSAATACLYGLCEAAILAAGYAPAIGFLHRGKPQSFVYDVADLYKVETVVPTAFSIAAKi 242 Rhodospirillum ...
WP_011448384 163 NGRRYDPHS-WGSADLPNRCLSAATASLYGICEAAVLAAGYSPSIGFLHTGKPLSFVYDIADLFKFETVVPAAFKTAAL- 240 Methanospirillu...
WP_010933633 177 KGRRFEPGK-FEMSDTTNKILTASNAALYSIILSAVHSMGYSPHIGFIHSGSPLPFIYDLADLYKQQVSIDLAFSLTADm 255 Chlorobaculum t...
WP_003619879 167 SKREYKVDD-FESETPINKALTAAHQALYGLSYSVIVALGASPGLGFIHTGHDLAFVYDFADLYKADISIPIAFETVAKy 245 Lactobacillus d...
WP_011601714 162 NRRVYTHGDpFADGDDINRLLSAGHSCLYGICHAAIIGIGASPALGFVHTGSAISFVLDIADLYKAEYTIPLAFDLAA-- 239 Frankia alni
WP_011273274 167 KKRMYDPQN-FSSGDPINRTLTAANAALYGVAHAVIASLGFIPSLGVIHQGTERAFVYDIADLYKAEISIPAAFDAVAE- 244 Corynebacterium...
WP_011458705 165 QGR--------EEKSALNTSIGFATSCLYALCEVAILAAGYHPGIGVVHSGNPRSLVFDLADTVKFKTVVPLAFEIAAT- 235 Albidiferax fer...
WP_011292015 173 FKRNYNPHD-WDDQDPVNKALSASNAALYGVVHSVLAHLGCHPALGFIHSGKQDAFVYDIADLYKARTTIPLAFSLSRT- 250 Thermobifida fusca
3NKD_A       239 -----NPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272 Escherichia coli K-12
WP_000144847 239 -----QPAEPDKEVRLACRDIFRSTKLTGKLIPLIEKVL 272 Escherichia coli
WP_011387928 243 aagkgDDSPPERQVRIACRDQFRKSGLLEKIIPDIEEIL 281 Rhodospirillum rubrum
WP_011448384 241 -----NPREPEREVRYACRDLFRETQLLKRIIPTIEEVL 274 Methanospirillum hungatei
WP_010933633 256 -----AGYYDRHKIASEFRKRVIEIDLLGKIGPDIETIL 289 Chlorobaculum tepidum
WP_003619879 246 -----GDDDIASRIRHAMRDKFRETKLIKQMVVDLKHLL 279 Lactobacillus delbrueckii
WP_011601714 240 -----AGTVEERDIRTAFRDKVADGHLMGRIVRDLKDLL 273 Frankia alni
WP_011273274 245 -----NELTADVNIRRVIRDYVVKKNLIPTMIRDLMFLM 278 Corynebacterium jeikeium
WP_011458705 236 -----SPSNLNMAVRHGCRDLFSRESMFETLLGHLENIF 269 Albidiferax ferrireducens
WP_011292015 251 -----A--NPEQEARLRLRRDLKLYRLIPQIVRDVQTLL 282 Thermobifida fusca
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