2D36,1I0R,1YOA,3CB0,2R0X,2ECR,2QCK,3BPK,3HMZ


Conserved Protein Domain Family
Flavin_Reduct

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smart00903: Flavin_Reduct 
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Flavin reductase like domain
This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.
Statistics
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PSSM-Id: 214900
Aligned: 349 rows
Threshold Bit Score: 34.8269
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2D36_A     30 RKFPLGVAIVTTNW-KGELVGMTV-NT-FNS-L-SLN-P---PLVSFF--A-----D-------R---MKG------NDI 77  Sulfolobus tokodai...
YP_972577  22 ivVPRPIAWISTLSeTG-VVNLAP-FScFTF-V-SNK-P---PLLGVN--I-----G-------R---KAG------RRK 70  Acidovorax avenae ...
YP_501715  10 SVFPLPITLISTISsKG-IRNIAP-YS-CVM-------PilrPLDLVC--I-----At-----aK---RRD------TLD 58  Methanospirillum h...
YP_887286  26 AVVPRPVAWTSTVSpDGIP-NLAP-FS-FFT-VvSSQ-P---PMVLLS--V-----EyqpdgrlK---DSA------AN- 80  Mycobacterium smeg...
NP_900582  20 cvLPRPIAWVSTQDlKG-VCNLAP-FS-FFN-VmSVN-P---PLLGIS--IlkqapE-------R---DKD------TLA 73  Chromobacterium vi...
EGF29055   20 litPRPIAWVSTLSaDG-VANLAP-YS-FFGgV-GAN-P---PTVMFCp-V-----N-------R---LDG------TPK 69  Rhodopirellula bal...
YP_488007  33 AVIPRPIAFVTSLGp-GGIVNAAP-FSqFVI-L-AVD-P---GLLGFS--V-----G-------P---RTGsdvakdTLA 87  Rhodopseudomonas p...
NP_887656  25 SVVPRPIALVTSLg-EDGVLNAAPfSS-YVV-L-SID-P---PMLGIS--V-----Af------R---DDG------ACK 74  Bordetella bronchi...
YP_552402  35 ivaPRLIGWISSRDtEGT-LNLAP-YS-FFG-A-FATfP---PIIGFCseG-----R-------K---DSV------TN- 84  Burkholderia xenov...
YP_863055  21 aigPRPIAFASTIDkDGNP-NLSP-FS-FFN-VfGAN-P---PVLIFS--P-----A-------RrgrDNT------TKH 72  Gramella forsetii ...
2D36_A     78 P----Y----KESK---YFVVNF--TDNEELFNIFALKPVkERFREIKYke--gI-----GGCPILYDSYAYIEAKLYDT 137 Sulfolobus tokodai...
YP_972577  71 DtgthI----LARR---EFVVNIghGGQLQQIHESSAEHPpEVSEADLLgl--aTapgeaVAVPRIADAGVAMECRLSQV 141 Acidovorax avenae ...
YP_501715  59 N----I----KETG---EFVINMatTDLTDAVIPTARISPpEEDEFISAgl--dEkpsvvVKPPGIMGCYAWMECTLDKL 125 Methanospirillum h...
YP_887286  81 -----I----AATG---EFVVNIapAAMAPAVDLTSAQVDpAVDEFALAgl--tPapcrhVRPPRIAETPISLECRLHTT 146 Mycobacterium smeg...
NP_900582  74 N----I----RLTG---ELVVNIvsQPLAAAMNASCGAYPaDVDEFELAgvaktDss--tVKPPGVAEAPVRLECTLHQC 140 Chromobacterium vi...
EGF29055   70 D----TlanvRANG---QFVVNVvtEEFAETMKQSAADVRpDEDEFVLTgl--qKapsvkVEVPRVADVVAAMECEMLTS 140 Rhodopirellula bal...
YP_488007  88 N----V----QRAG---EFVINMvpEGWEQSVQQASEEYPpDVSEVDLLgf--aTlpsrhIRTPRLAGSKIQFECRLDQV 154 Rhodopseudomonas p...
NP_887656  75 DtrrnI----ERSG---EFVINSvtADMVAQVQQCGQAYPsDVSEAQAAgl--tAiasqvVSVPRIAQSPLQFECRLRHC 145 Bordetella bronchi...
YP_552402  85 -----I----EATG---EFVWNLanKPLAEQMNRSSAPVPpSVDEFELAgl--tPapgrnVAVPHVAESPAALECKLLQV 150 Burkholderia xenov...
YP_863055  73 T----F----ENAKnvdEVVINIvnYDIVQQMSLSSTEYAeGVNEFEKSgl--tMlksdlVKPFRVAESPVQLECKIKEV 142 Gramella forsetii ...
2D36_A    138 IDVG-------D----H-----SIIVGEVIDGYqiRDN 159 Sulfolobus tokodaii str. 7
YP_972577 142 IPFG-------Dt--gA-----EFFVGEVLRFHv-REG 164 Acidovorax avenae subsp. citrulli AAC00-1
YP_501715 126 IEEP-------S----Y-----ILIIGKVVHLEi-LDE 146 Methanospirillum hungatei JF-1
YP_887286 147 VQPG-------S----D-----RLIIGEVVAFHl-DSS 167 Mycobacterium smegmatis str. MC2 155
NP_900582 141 LTFG------------HgsgagNLVLAEVKCIHv-AEG 165 Chromobacterium violaceum ATCC 12472
EGF29055  141 MQLG-------PgrggA-----NLVVGRIVSFYv-ADS 165 Rhodopirellula baltica WH47
YP_488007 155 LTFG-------Da--pN-----HLVVGRIVAMHv-AAG 177 Rhodopseudomonas palustris HaA2
NP_887656 146 VEFG-------Qr--rS-----ALLVGEVVLAHa-Avg 168 Bordetella bronchiseptica RB50
YP_552402 151 VRLHtldgtpmD----N-----YLSLGQVVGVHi-NEA 178 Burkholderia xenovorans LB400
YP_863055 143 VETG-------TeggaG-----NLVICHVVKMHv-KEE 167 Gramella forsetii KT0803
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