183222551 15 LECASHVLTPIPITEE--------------TYQVskqiqWIQTPNKLILKNTSfdrnfielslNEP-FLTVSEVNTISKY 79 189912586 20 HVLTPIPITEETYQVS--------------KQIQ-----WIQTPNKLILKNTSfdrnfielslNEP-FLTVSEVNTISKY 79 294500393 1 MSGTLNVTKGVNVEIL--------------QDGF-----EVALNGVVLLQHTI----------QKPmLFVGHGEETIEMY 51 119716689 45 VDTVTPGSLDVTPGATgtwtvgdltvdvsaAAGL-----SVRSGSRTVWAAPP----------GGAfVTGGRGSVSWEEH 109 222100524 1 --------MMIKHEIK--------------GNQF-----YVAVNDHILISSKN--------------IWEGFGKERIKEY 39 300870750 1 -------MPKLTKKIN--------------NDKL-----EIFLDDVLILEHSK----------DNPaIFVGNGREDILMY 44 87200459 1 --------MNLRFVAG--------------TEGF-----DLRIGDRVVLRHSE----------SCPaLVMARGNPEVVMY 43 103487148 5 SRGERKQGVKLRFFES--------------RDGF-----ELRFGSHLVLRHVS----------DCPaVVIARGAPSIEMY 55 15891648 1 ----------MHFETT--------------KDGF-----TIAIGNRIILSHSP----------DKPaFFAGFGEERMDMY 41 24215643 26 TKIDLPSKKQFSFGKNfqa--------iqkENVL-----EIRSVAGTFLELSM----------VKPfLSAAKGEQEVKYK 82
183222551 80 RmasfkfeestkrtcseqtvdsikketGKITIQGKLSGKN----------CVTNyqvlfltksdte-------------- 135 189912586 80 RmasfkfeestkrtcseqtvdsikketGKITIQGKLSGKN----------CVTNyqvlfltksdte-------------- 135 294500393 52 R--------------------------GNFDIKDYVTERT----------ALRYanveemegaykidlsnlkngdtmlsl 95 119716689 110 R--------------------------GYFWPTVSYTDRLteqsvdtvqaSADDivltgrlsgplapggdaaytlt---v 160 222100524 40 H--------------------------GHFTIKSTVKEYY----------PFKGsielvsenpf---------------- 67 300870750 45 R--------------------------GNFRITNLEDSKI----------PLKlfketnngiefyygddsltl------- 81 87200459 44 R--------------------------GNFRISDKPFEEL-------------Vplawrqceggvelldsgapv------ 78 103487148 56 R--------------------------GNYRIDDSPEGIIrcadwradgadmllldagep-------------------- 89 15891648 42 R--------------------------GNFDIEDYVIERT----------ALRHaevsgdsvtlssapgqapr------- 78 24215643 83 F--------------------------ASFHIKDKIIFRCdfqsietmisSLNDfkisgilegkgcrskyeivf------ 130
183222551 136 --------lefkitvsdetlNRIHLVYASHPEEKIFGLGEQFTYDEFKGKKPFFFTEEQGIGRGDQP-ITAGANLLAGAG 206 189912586 136 --------lefkitvsdetlNRIHLVYASHPEEKIFGLGEQFTYDEFKGKKPFFFTEEQGIGRGDQP-ITAGANLLAGAG 206 294500393 96 ivkeeenrlkveyqkndaniNRFWLRVAADKQEKVYGCGEQLSHFNMRGKNFPLWTSEPGVGRNKQTyVTWQADVVDKAG 175 119716689 161 raraaggaaldltssaavplTSVALVSGRSAHAGVHGFGEQFSDFDLDGRLLPIVAREQGVGRGEEPiTSLADATNHGAG 240 222100524 68 ----------eihikssrdiNRLLIKTELAKDEVIFGGGEQYSELNLKGKRFPLFVQEQGVGRGKN--LISLLAYLKKVR 135 300870750 82 -ifneektkcalklnaskeyTRFWIRIKSDKDEHMYGLGEQMSHFNLRGKLFPIWSSEPGVGRNKNTyVTWMSDSTGMAG 160 87200459 79 -asivlagnsfeiraadpahDRLRIRFHAEAGECVWGGGEQMSYLALNGRNFPIWTSEPGVGRDKSTeLTRRMDAEGMAG 157 103487148 90 tvrlgiegralrvealrsgyDRITTRFFAEPGEAVWGGGEQMSYLMLAGRRFPMWTSEPGVGRDKSTeLTRIMDAEGMAG 169 15891648 79 -lrltldgnairltaldetiNRLWLRVVAETDEHVWGGGEQMSYFDMRGRRFPLWTSEPGVGRDKTTeITFKSDVSGKAG 157 24215643 131 -ipldetsirfkikiedvslNRSYFRMVSDETENIFGLGEQFSHFNLKGKTPFLFTEEQGVGRGDQP-ITTGANLLADAG 208
183222551 207 GNAYTTYAPIPHYISSENRSVFFENSGYAKFDFSDA-----RKTKVEF----WdfqsEKSVTGTIWLASSAKSLIETYTK 277 189912586 207 GNAYTTYAPIPHYISSENRSVFFENSGYAKFDFSDA-----RKTKVEF----WdfqsEKSVTGTIWLASSAKSLIETYTK 277 294500393 176 GDYYNTNFPQPTYVSSKKYYCHVETTAYADFDFRNE-----AFHELQV----W----EVPKYMLFETADTYLELVEKITG 242 119716689 241 GTRDMTYAAWPSFVTDDLRGLRLDAAASSSTAFAVAdtrdpDAVALEL----W----SPTLSAQASAAATPARLVAAQQA 312 222100524 136 GSWYSTYFPQPVFFSNKGYGIVFKTYAPMIVDLR-K-----NIALFEI----W----SNECNI-IVLSGTLEEMVRDLFK 200 300870750 161 GDYWNTNYPQPSYMSSKKYSLFSDSYAYSEFDFRNE-----NFTEIHV----W----EVPEQILLWKEDSFYKLMESFTE 227 87200459 158 GDYWNTNYPQPTFITSRWIAVHLDASFYSVLDFTDP-----AGHLVEV----W----SGAARFEVFSADGPQDLVGQLST 224 103487148 170 GDYWNSNYPQPTFLTSRWIAVHLDDFGYSVLDFSDP-----ATHRVDY----W----GTQARFEFFAADGPAELVGRLST 236 15891648 158 GDYYNTNYPQPTWLSSRKYALHVETSAYSVFDFRNG-----DFHEIEI----W----AVPEKIEFFAGDSFADIVSALSL 224 24215643 209 GNEYTTYAPIPFFLTSKNRSVYFENSSYSKFDFSNSeeilvEFRENGLqgiiW----KDSSPIK---------LVQKFTE 275
183222551 278 KTGRFPKLPDWAY-GTWLGIQGGTEKVTTIVKQAKAAGNPVTALWIQDWCGRRVTNFGDQLKWRW---YADETLYPDFKK 353 189912586 278 KTGRFPKLPDWAY-GTWLGIQGGTEKVTTIVKQAKAAGNPVTALWIQDWCGRRVTNFGDQLKWRW---YADETLYPDFKK 353 294500393 243 LFGRQPELPEWVYnGVVLGIQGGTDVVEQKLEKVLAKGMKVSGVWCQDWQGKRITSFGKRLMWNW---KWNESEYPELDK 319 119716689 313 GDQRRP-LARWATrGAIVGLQGGTQEVRRELGRLLDAGANVSGVWIQDWTGKRTTSFGDRLWWTW---QLDRERYPGWAR 388 222100524 201 IFGGAFDYEDWMF-GVWLASQGGTENIERIIKTAREWNIPVHAVWAQDWCGKVYTKFGRQVFWNW---EYDKEDYHDLPE 276 300870750 228 YFGRQPNIPDWMNdGIVVGIQGGWDKIKRVLNDLKSYGVSVTGVWIQDWEGIRMTSFGQRLMWNW---AHDPKRYPDFKE 304 87200459 225 RFGRQPELPEWAIgGAIVGLKSGAS-SFDRLEKFIDAGAAVSGLWCEDWAGIRETSFGRRLFWDWhsgERSGARYPQLHE 303 103487148 237 RFGRQPALPDWAIgGAIVGLKSGAS-SFERLERFLDAGAVVGGLWCEDWAGVRETSFGRRLFWDWvrgARSEQRYPDLRT 315 15891648 225 HFGRQPELPDWVYnGAIIGLKDGVN-SFARLEKIRAAGTKVSGLWCEDWVGLRQTSFGARLFWDW---QANDTRYPHLRQ 300 24215643 276 KTGRAPELPDWAY-GTWLGIQGGKEKVLKQIEAARKEGNPITALWIQDWVGRRKTSFGSQLWWRW---IADEKFYPEFKN 351
183222551 354 FVKSMNDENVQVLGYINSFLADtdpkkpgddfTNPLLTEAKSKGYLVKNEKGED-YLIQTVGFPAYLIDLTNPAAVKWTK 432 189912586 354 FVKSMNDENVQVLGYINSFLADtdpkkpgddfTNPLLTEAKSKGYLVKNEKGED-YLIQTVGFPAYLIDLTNPAAVKWTK 432 294500393 320 KIAEWKENDIRFLGYINPYVAI----------EGDLYKEAEDKGYLALNTEGNT-YLVDFGEFYCGVVDFTNEEATEWYK 388 119716689 389 LVRRLSALGITTTTYVNPFLVDaapk--gdpgIRNLWAEARDRGFLVTDESGAP-YALDQGEFEASLVDLTDPAARSWFA 465 222100524 277 YIKKWHEEGIRFLGYINPFLNK----------EGNLYKEALEKGYLVKKKDGSV-YDIVVTTFPAGLIDLSNPDAFEWYK 345 300870750 305 NVRKLKEEGIRFLAYSNCYLAI----------DGALFKEAKDLGYLAKNDKGEI-YEVDFGEFYCGIPDFTREEVCKWFA 373 87200459 304 RIQALEARGIRFLAYANPYIAV----------DGDLYQEGRAGGHFCLRRDSDEvHLVDFGEFDCGVVDFTREETCAWFA 373 103487148 316 RIAALEERGIRFLAYVNPYLAV----------DGTLFEQAKADGHFCLRQDSDEvYLVDFGEFYCGVLDFTRAATRDWFA 385 15891648 301 KIAELADQGIRFLGYVNPYLCV----------DGPLFPVAESAGYFATDVDGKT-ALVDFGEFDCGVVDFTNPAAADWFA 369 24215643 352 FCSDLNKQGIHVLGYLNPFLAT----------EGPLYEEAVQKGYLIKDKNGNN-YVIETVGFPAVLLDLTHPEAVKWIQ 420
183222551 433 -DLIKKNLIGMGLSGWMADFGEWLPYDAKLHSGVDAKIYHNRYPVDWARINREAIKESGMEGKIVFFTRAGYSYSNAHST 511 189912586 433 -DLIKKNLIGMGLSGWMADFGEWLPYDAKLHSGVDAKIYHNRYPVDWARINREAIKESGMEGKIVFFTRAGYSYSNAHST 511 294500393 389 -QVIKENMIDFGLDGWMADFGEYLPTDVVLKNRIDAKIMHNAWPTMWAKVNYEAVSEAGKLGEIVYFMRAGYTGIQKYCT 467 119716689 466 -EVIARYVLADGVRGFMADFAEGLPFDARLHTGTPAT-LHNRWPALWARTVRLACRRAEQ-PRCVTWFRSGALGQAAHAP 542 222100524 346 -SIILNNMISIGMDGWMADFGEYLPMDAVLKYSSGKE-YHNKYPVEWARLNFEAVKASSK--KVVYFMRAGFLGSTRFCP 421 300870750 374 kRILVEEMLDYGIEGWMADFGEYLPIDVKLSESVAMK-KHNEWPVLWAKVNDMALDMAGKKGDIFIFMRASGSRAQQYAP 452 87200459 374 eRVLGREMLDIGISGWMADFGEYLPTDLRLADGSDPMEAHNRWPVLWAEVNARALASRGKTGDALFFMRAGFSGVQAHCP 453 103487148 386 eHILGREMLDNGIAGWMADFGEYLPTDVRLADGSDPMEAHNRWPVLWAEVNARAVASRGKTGEALFFMRAGFSGVQAHCP 465 15891648 370 eEIIGKNMLDFGLSGWMADFGEYLPIDIKLSNGVDAKLMHNAWPTLWAEVNAKGVESRGKTGEALFFMRAGFTGVQAHCP 449 24215643 421 -KIIQKNLIGVGLSGWMADFGEWLPLDASLYSGISADVYHNVYPVEWARINREAIRNVGKEGKIVFFTRSGYSGSMKHST 499
183222551 512 LFWEGDQMVSFGTNDGLPSSIVGLTTSGISGYALNHSDIGGYTTisnpLKNYHRTKEVLLRWAEVSAFTPVFRTHEGNRP 591 189912586 512 LFWEGDQMVSFGTNDGLPSSIVGLTTSGISGYALNHSDIGGYTTisnpLKNYHRTKEVLLRWAEVSAFTPVFRTHEGNRP 591 294500393 468 LLWGGDQSVDWSLDDGLASVIPAALSSGMIGCGLHHSDIGGYTS----LHGNKRSKELLMRWAEMGAFTPMMRTHEGNRP 543 119716689 543 LFWNGDQLVTFGREDGLASALLGTLSAGVSGWPLVHSDVGGYTSvnavVKNYVRTPELLARWAEFQAFGVVLRTHEGNRP 622 222100524 422 AFWTGDQNVDWSFSDGLPTVIPAMTSSSLCGVRHIHFDIGGYTS----LFWMKRTPELFMRWTEIAAFSPVMRTHQTNRP 497 300870750 453 VLWAGDQSVDFTKDDGIATVIPAALSSAVSGFCYHHSDIGGYTS----LFGNVRTPELNDRWIEFAAFTSTMRSHETNRP 528 87200459 454 LLWAGDQSVDFTRHDGIGTVITGALSAGLVGNAYSHSDCGGYTS----LHGNVRTEELLHRWCELAAFAPVMRSHEGNRP 529 103487148 466 LLWAGDQSVDFTRHDGIGTVLTGALSAGLVGNAYSHSDCGGYTS----LHGNVRTEELMQRWCELAAFAPVMRSHEGNRP 541 15891648 450 LIWGGDQSVDFSRHDGLVTVICGALSSGLMGNAYHHSDIGGYTS----LFGNVRTAELIMRWTEMAAFTPVMRTHEGNRP 525 24215643 500 LFWEGDQMVSWGEHDGIVSAVTALLSGGLSGISINHSDIGGYTTinnpIRNYHRSKELFLRWAELNVFSSVFRTHEGNRP 579
183222551 592 LKNWQVYtytkpdgtkslGDEDTVQLFAKIARIHFALKPYIQSLVEEASKTGLPVVRHNAIVEPEDKILLQYKYQFFLGD 671 189912586 592 LKNWQVYtytkpdgtkslGDEDTVQLFAKIARIHFALKPYIQSLVEEASKTGLPVVRHNAIVEPEDKILLQYKYQFFLGD 671 294500393 544 DDCFQFD-----------GDEETLEHLARMSNVYVTMAPYIKSLVEENARRGIPVQRPLFMHYEEDEKTYDIQYQYLFGE 612 119716689 623 ADNPQVF-----------STRDTARAFARSTRIFGALAPYRDRVVRAATRTGVPAVRPIWLVAPGSSAAAS-DTEFFLGR 690 222100524 498 VSNIQFD-----------SNHDILRHFSKMANMHVLLIDYLKVEFKKAIDENLPVVKHLALNYPEDPESWQIKYQYLLGN 566 300870750 529 NDNIQLY-----------DSPTTMVLLSKMVRIFKALKEYRINFMKDAKDKGISLMRPLFFEYENDKESYSIDYEYMLGS 597 87200459 530 DDNLQYD-----------STPDLLACFARWSRVHAHLAPYVRHLCTEARESGLPAQRPLFLHYPQDSALFTVQDQYLYGA 598 103487148 542 DDNLQYD-----------STAELLACFARWSRVHAHLAPYVRHLCDEAQETGLPAQRPLFLHYPDDPTLFTVQDQYLYGA 610 15891648 526 RDNLQID-----------QDETVLAHFARMTAIYVALAPYLKSLSAEAAKTGLPVQRPLFLHYENEPQTYAVQDCYLYGA 594 24215643 580 EKNHQSY-----------SDEETIQEFARYGKMHFALKEYLKFLIKEAFKTGLPVVRPLYLHYSMDRKTHDLKREFLLGE 648
183222551 672 DLLVAPVVESNEIVQEVYLPR-GKWSHIWTGTNFEGNrKIQVSAPIGKPPAFIRVGGKS-EMLIRSSLESIR 741 189912586 672 DLLVAPVVESNEIVQEVYLPR-GKWSHIWTGTNFEGNrKIQVSAPIGKPPAFIRVGGKS-EMLIRSSLESIR 741 294500393 613 DVLVAPVHQENQTEWEVYLPE-DQWVHVWSGEAYTGG-SVTVQAPLGYPPVFYRKKSIW-SELFSKLIHI-- 679 119716689 691 HVLVAPVLEAGATSVPVILPP-GRWVHLFTGRGYAGDrTVTVPAPIGRPAAFVREGGPW-STRLPARFRAAG 760 222100524 567 DILVAPVLKKKTRKWKVFLPRrEKWVHLWTEKMFSGG-WIEIDAPLGEPPVFVRLGSEFlEKILAASRDVQE 637 300870750 598 DILVAPVWKEKTDNWKVYLPN-DKWVHLWSDKEYDGGqTITIESGVGKIPVFIKKSSKY-LDLFRSLKSL-- 665 87200459 599 DLLVAPVVEEGARRRQVVLPGtGIWRHCWTGEDFAPG-THDISAPIGQPPAFYRPDSAF-ASLFAGLKGVLE 668 103487148 611 DLLVAPVVEQGIERRSVVLPGkGPWRHCWTGEEFAPG-VHQIPAPIGMPPVFFRPDSGF-APLFGRLAEIWK 680 15891648 595 DMLVAPVWKAGETQRSLYLPGhGEWVHLWSGKRHAGGrDITVETPLGEPAVFYRADSSH-HRLFEQLRTIG- 664 24215643 649 DLLVFPVLEEGEIFVSGYLPE-GEWEHVWTEKIFTGKnEVKVEAPLGAPAIFLKKNGIWySKLKNALYKFKK 719