Conserved Protein Domain Family
PRK10846

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PRK10846: PRK10846 
bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional
Statistics
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PSSM-Id: 182774
Aligned: 89 rows
Threshold Bit Score: 750.754
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
22125497   27 MNNHQTPQATSPLAAWLCYLEHLHSQPIELGLERVKQVAERLDLLKPAPKIFTVAGTNGKGTTCCTLEAILLAAGLRVGV 106
197285644   2 SNIITAPQATSPLSVWLSYLEHLHSSAIDMGLERVGKVGQLLNVLRPAPKVITVSGTNGKGTTCHMLESILMASGLKVGV 81 
300724018   2 FDTFQTPQATSPLMTWLSYLDNLHTKAIDMGLERVGKLGKQLDLLNPALKVITVSGTNGKGTTCHTLESIFLAAGLKVGV 81 
290475955   2 SDILQIPQATSSLITWLSYLGNLHAKAIDMGLERVGALADQLDLLHPAPKVITVSGTNGKGTTCHTLESILLAAGLKVGV 81 
37527056    2 PDTLQIPQATSPLMTWLSYLGNLHTTAIDMGLERVGKLARTLALVNPAPKVITVSGTNGKGTTCCTIESILLAAGLRVGV 81 
50121978    1 MDTLQIPQATSPLVTWLHYLEHLHAQAIDLGLERVKQVAEHLQLLQPAATIFTVAGTNGKGTTCCTLESILLAAGLRVGV 80 
253689173   1 MDTLQTPQATSPLVTWLHYLEHLHAQAIDLGLERVKQVAEHLHLLQPAPTVFTVAGTNGKGTTCCTLESILLAAGLRVGV 80 
242239991   1 MDNLQIPQATSPLAAWLHYLEHLHGQPIDLGLERVKQVAEHLQLLQPAPWVFTVAGTNGKGTTCCTLAAILMAAGMRVGV 80 
271501290   1 MDNLQTPQATSPLATWLHYLEHLHSQAIDLGLDRIRHVAECLQLQQPAPRVFTVAGTNGKGTTCCTLESILSAAGLRVGV 80 
251788991   1 MDNLQTPQATSPLATWLHYLENLHSQAIDLGLDRIRQVAEHLDLLQPAPRVFTVAGTNGKGTTCCTLESILSAAGLRVGV 80 
22125497  107 YSSPHLLRYTERVRIQGQELSEAEHSHSFAQIEAGRGDISLTYFEFGTLSALQLFKQAKLDVVILEVGLGGRLDATNIVD 186
197285644  82 YSSPHLVRYTERVRIQGKELSPAEFCQVFAEIEQTRGDISLTFFEYGTLAALKLFQQAQLDVVILEVGLGGRLDATNIVD 161
300724018  82 YSSPHLVRYTERVRIQGKEPAEQDFCRVFADIEAQRGDISLTYFEYGTLAALQLFKEADLDVVILEVGLGGRLDATNIVN 161
290475955  82 YSSPHLVRYTERVRIQGKEPAEQDFCRVFADIEAQRGDITLTYFEYGTLAALQLFKEADLDVVILEVGLGGRLDATNIVD 161
37527056   82 YSSPHLVRYTERVRIQGKELPEQEFCRVFADIESRRGDISLTYFEYGTLAALQLFKQACLDVVILEVGLGGRLDATNIVD 161
50121978   81 YSSPHLVRYTERVRIQGHELSDAQHTQAFADIEAGRGAVSLTYFEFGTLSALQLFKQANLDVVILEVGLGGRLDATNIVD 160
253689173  81 YSSPHLVRYTERVRIQGKELPEAQHTQAFADIEAGRGAVSLTYFEFGTLSALQLFKQANLDVVILEVGLGGRLDATNIVD 160
242239991  81 YSSPHLLRYTERVRIQGQELPESLHCQAFADIDAGRNGISLTYFEFGTLAALQLFKQARLDVVILEVGLGGRLDATNIVD 160
271501290  81 YSSPHLLRYTERVRIQGQELAESLHAEAFAAVEAGRGGTSLTYFEFGTLAALWLFKQAQLDVVILEVGLGGRLDATNIVD 160
251788991  81 YSSPHLLRYTERVRIQGRELPEFHHAQAFAAVEAGRNGISLTYFEFGTLAALWLFKQAQLDVVILEVGLGGRLDATNIVD 160
22125497  187 SDVAAITSIALDHTDWLGYDRESIGREKAGVFRGGKPAVVGEPDMPQSIADVAAELGAQLYRRDVAWKFSQQEpfdqqep 266
197285644 162 ADIAAITSIALDHTDWLGADREHIGHEKAGIFRKNHYAVVGEPDMPLSIAQVAQQKQAKLFRRGVDWSFSIDG------- 234
300724018 162 ADIAAITSIALDHTDWLGSDREHIGREKAGIFRPGRFAVVGEPEMPNAIAEVADELGARLFRHGVDWHFSQDI------- 234
290475955 162 SDVAAITSIALDHIDWLGADREHIGREKAGIFRQGRFAVVGEPDMPHTIAEVADELGAKLFRRGADWDFSQDA------- 234
37527056  162 ADIAAITSIAIDHIDWLGADREHIGREKAGIFRKDRFAVVGEPDMPSSIAEVAGELGAKLFRCGIDWRFSQQN------- 234
50121978  161 ADVSVVTSIAIDHTDWLGNDRESIGREKAGIFRQGRPAVVGEPDMPGTIADVAAEKGALLRRRGRDWEFSVQR------- 233
253689173 161 ADVSVVTSIAIDHTDWLGNDRESIGREKAGIFRQSRPAVVGEPDMPGTIADVAADKGALLRRRGRDWDYSVQR------- 233
242239991 161 ADVAVVTSIALDHTDWLGNSRESIGREKAGIFRANKPAVVGEPDMPDSIAAVAAEKGALLFRRGADWSFDVQK------- 233
271501290 161 ADVAVVTSIALDHTDWLGNDRDSIGREKAGIFRGNRPAVVGEPDMPVSIAAVAQEKGALLFRRGADWQFSLQD------- 233
251788991 161 ADVAVVTSIALDHTDWLGNDRESIGREKAGIFRGNRPAVVGEPDMPVSIAAVAQETGAHLFRRGADWQFALQG------- 233
22125497  267 vdqqiNGWHWQCGERQLTGLPVPNVPLANAATALAVLHY-------SELPLSDEAIRQGLQAASLPGRFQVVSEQPLLIL 339
197285644 235 -----DHWHWRSADKQFEKLPIPNIPLANAGTAMAVIRCllksddkVSQGITHQSIVEGMSKAQLPGRFQIISQHPLVIF 309
300724018 235 -----NSWNWLTHDQQFNELPLPNLPLANAATAMGVIHCllqqddhISRAINEKAIHAGLKNAQLPGRFQAVRQNPLVIL 309
290475955 235 -----NSWYWRTGDQQFSELPVPNLPLANAATAMGVIYCllqqndnVSQAINEQAIREGLSKAQLPGRFQIVRENPLVIL 309
37527056  235 -----KNWHWQSDDRLFSNLPLPNVPLMNAATAMGVICCllrqddkVSRAINESAIHQGLQNAQLPGRFQIVREKPLLIL 309
50121978  234 -----ETWSWQDKQRELSRLPLPNVPLPNAATALAALHY-------SSLNVSEEAIRQGLQRAALPGRFQIVQESPRLIL 301
253689173 234 -----ETWSWQDKQRELSRLPLPNVPLANAATALAALHY-------SSLNVSEDAIRQGLQHATLPGRFQTVQESPRLIL 301
242239991 234 -----DAWRWQCGDKHIAGLPIPSVPLPNAATALAALQV-------SGLDIDEDIIRLGLRNAALPGRFQIVREKPLLIL 301
271501290 234 -----GGWRWQSGDVCYEALPIPSVPLANAATALAALQV-------SDIALSVNVIRQGLRQAQLPGRFQIVSEKPLLIL 301
251788991 234 -----DGWRWQCDDVQYDALPVPTVPLANAATALAALYA-------SDIALTTEVIRQGLRQAQLPGRFQIVSEKPLLIL 301
22125497  340 DVAHNPHAARYLVNRLAQVinpvnaSK--QGKVRAVVGMLSDKDIAGTLACLSERVDEWYCAPLEGPRGASAGQLAEHLV 417
197285644 310 DVAHNPHAAGYLAEKLAQL------PRysDTKVRIVVGMLGDKDIAGTLACLSPQADQWYVAPLNEFRGASAQVLAQHLD 383
300724018 310 DVAHNPHAAGYLVQKLAEL------PRlpERKIRGVVAMLADKDIAGTLACLSQQIDEWYCASLYEFRGAEAEVLAGHLT 383
290475955 310 DVAHNPHAAGYLVQKLAKL------PRapDSKIRGVVGMLEDKDIAGTLACLAQQVDEWYCASLHEFRGAEANILAEHLG 383
37527056  310 DVAHNPHAAAYLVQKLAQL------PRqpGSRILGVVGMLGDKDIAGTLTCLSQQINEWYCAPLTEQRGADAQTLAQHLG 383
50121978  302 DVAHNPHAAAYLANRLAGL------PK--AGKMRAVVGMLSDKDIAGTLAHLIPLIDEWYCASLEGPRGATAQQIAEHLT 373
253689173 302 DVAHNPHAAAYLANRLAAL------PT--SGKIRAVVGMLSDKDIAGTLAYLTPLVDEWYCAPLEGPRGATAQQIAEHLT 373
242239991 302 DVAHNPHAAGYLASRLNAL------PR--YGRVRIVIGMLADKDIPGTLAYLKPLADDWYCAPLDGPRGAGVEQLACHLA 373
271501290 302 DVAHNPHAAAYLAARLADL------PR--TGQVRAVVGMLADKDIPGTLAHLKPQVDVWYCAPLEGPRGASADQLAEHLA 373
251788991 302 DVAHNPHAAAYLAARLADL------PR--TGQVRAVVGMLADKDIPGTLAHLKPQVDVWYCAPLEGPRGAGAGQLAEHLA 373
22125497  418 SARQFSDVETAWRQAMQDADTQDVVIVCGSFHTVAHVMAALHL 460
197285644 384 YPAVFDSVEQAWQQAISEAQKNDIVVVCGSFHTVAHVMELLEK 426
300724018 384 HPRTFSAVEQAWKQAMEDASVQDVIVVCGSFHTVAHVMEALEE 426
290475955 384 DARTFVEVEQAWHQAMAEASVQDIIVVCGSFHTVAHVMEALEE 426
37527056  384 QPRIFTDVESAWHQAMVDADEQDIVVVCGSFHTVVHVMEALDR 426
50121978  374 RSQSFPDVVTAWQQAMSDATEQDIVIVCGSFHTVAHVMEALDE 416
253689173 374 RSQSFPDVVAAWQQAMSEAAEQDIVIVCGSFHTVAHVMEALDE 416
242239991 374 GCGQYADVASAWRQAMQDAGPQDIVVVCGSFHTVAHVMEALEG 416
271501290 374 LCTRYSDVATAWRQAMQDAGENDVVIVCGSFHTVAHVMEALDG 416
251788991 374 DCTQYPDVATAWRQAMRDAGENDVVIVCGSFHTVAHVMEALDG 416
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