4INA


Conserved Protein Domain Family
Lys9

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COG1748: Lys9 
Saccharopine dehydrogenase, NADP-dependent [Amino acid transport and metabolism]
Saccharopine dehydrogenase, NADP-dependent is part of the Pathway/BioSystem: Lysine biosynthesis
Statistics
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PSSM-Id: 441354
Aligned: 373 rows
Threshold Bit Score: 102.993
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4INA_A        28 SHITLASRTLSKCQEIA-QsikakgYGEIDITTVDADSIEELVALinevKPQIVLNIALPyQDLTIXEACLRTGVPYLDT 106
WP_012793044  29 WHITVADHDLALIKSKT-Gk-----SYYVTPAAIDIRDEASRQKLi--qETDLVISLLPAqLHILVAKDCLQFSKNLLTA 100
WP_013768666  29 WFVTVADAQLENAEKKV-Gn-----HPNGRAVWLDVMKVNDRRELi--gRADVVVSILPAhLHLEVAHDCVKLKKHLITA 100
WP_014162420  26 HSVTVVDIDENNLKRAT-Gg-----HPRSQIIVGDAANETERFIEq--vKPHIVINLLPAqFMPPVAKKCVEFGINYVDP 97 
WP_008585121  29 WTLTLADINFELAQRKL-Nh-----HPAGTAVGIDLSKETERQALi--qKADIVISMLPPaLHILVAKDCLHLKKDLLTA 100
WP_015265636  29 RKVILADVDAKVAEKKL-Ag-----HPSGEAASIDIHDKRKLHTLi--kQVDIVVSMVPAfLHPLVAKAAVTERKHFFSA 100
WP_057952576  25 YGLTVASIDQKRALELL-Nn-----HPNGQFVYWDAEDEKGLHDLv--pKHDLTVSLLPYkFHVMVAKVCLEYKKHMVTT 96 
WP_067542603  29 CHFWIADLSVAHLEPIL-At-----KKGIKLIPLDSGNMTQRRDIi--qNSDLVISMLPAfMHPEVARDCVDFGKHFFSA 100
WP_006927860  26 VNLKVASLEFGNVRQLI-Es-----HPRASLQKLDVNDRQALRQVi--sEADVVISLLPWiHHMKVANLCLELNKHLVTS 97 
WP_076380647  29 WRVTIVDGNAGSIQEKImGn-----YPLVKGAIINLENETERVAYi--qESDLVISLMPPaLHIIIARDCVSFKKHLLTA 101
4INA_A       107 ANYEHPDlakfeyKeqwAFHDRyKEKGVXALLGSGFDPGVTNVFCAYAQKHyFD----EIHEIDILDcnAgdHGYP---- 178
WP_012793044 101 SYIDPEV------K---KLEKEiEDAGLLFMYEMGLDPGIDHMSAMKLIHS-IEkkggQISAFRSYC--GglVSPEsndn 168
WP_013768666 101 SYVSQEM------Y---RLGDEaRDRELIFMGEMGLDPGIDHMSAMKVINE-IKesggKITAFRSYT--GglIAPEsddn 168
WP_014162420  98 SYIKDEM------R---SLDAAaKEKGVLILCELGLDPGIDHMSAAKTIKE-IHekggLVDSFWSCC--GalPSLCdnnn 165
WP_008585121 101 SYIDDEL------L---QLKEQiEKNNLLFLCEMGLDPGIDHMSAMRIFDR-IRsnggTITSFRSHC--GglIAPEsdnn 168
WP_015265636 101 SYESAEM------K---ELAKEiTAHNLFFLNECGLDPGIDHMSAMKLIDA-EKaegnQIVLFKSYC--GglLSSEsead 168
WP_057952576  97 SYVKPEM------Q---SLYDEaVNKNVLLLNEIGVDPGIDHMSAMRIIDK-VHksggEIEEFFSIT--GalPDPRdvdn 164
WP_067542603 101 SYESDAI------R---ALKPEiESKGLFFLNECGLDPGIDHMSAMKIILE-AKqkgeEIRSFKSYC--GglLAPQsedn 168
WP_006927860  98 SYVKPEM------R---ALDAEvKKRGLIFLNEMGVDPGIDHMAAMKVINN-VKnrggKIISFYSYC--GglPAPQnnnn 165
WP_076380647 102 SYIDDSM------R---ALQPAiEQNDLLFLCEMGLDPGIDHMSAGRLIHS-IHtqqgIISSFQSHC--GglVAPEndtn 169
4INA_A       179 ----FATNfNPEINlREVSSKGRYWENGEWIETePX----EIXQVWDYPEVGPKDSYLLYHEeLESLvRNI--KgLKRIR 248
WP_012793044 169 -pwqYKISwNARNIvLAGNSGATYREKGKTKEV-SYqhlfDQSKTIHIPSLGKLAYYPNRDS-LNYI-SAYklEeVPTFM 244
WP_013768666 169 -pwhYKITwNPRNVvLAGQGTAQYLENGRLRYQ-PYhrlyKECRTIDIPEVGKMEAYANRDS-LLYR-DAYglAdIPNIL 244
WP_014162420 166 -plgYKLSwSPEALiGASKRTARFLRNGEVVVL-PDgetyKHPSLVDVEGLGCFEEYANADS-IPYI-ELYgiKeAKHVY 241
WP_008585121 169 -pwhYKISwNPRNItLAGQAGAIYKEDNTVRTI-SYpdifRNCPAIEAPVPGQWACYPNRDS-LHYI-PVYklEsAETVI 244
WP_015265636 169 npwkYKFTwNPRNVvLAGQSTSRFIRNGRYKFI-PYhmlfRRTDLISFKEEGDFDGYANRDS-LNYR-GVYglEgIPTII 245
WP_057952576 165 -plgYKFSwSPKGViLASKNDATYLHKGKEVYV-EPkalfQDIFEVDFPNVGTMDVYPNRNS-IDYI-DIYgiPeVKTIF 240
WP_067542603 169 -pwkYKFTwNPRNVvLAGQATSRYMDQGELKLV-PYhqlfRRVDEVSFVGLGKFDGYPNRDS-LSYR-SVYglEnIPTIL 244
WP_006927860 166 -plgYKFSwSPVGVmLAALSYGQYLKDGKVVKV-ASeqlfEHYWFLDVPGAGTFEAYVNRDA-LPYM-ELYgiQeAQSMF 241
WP_076380647 170 -pwhYKISwNPRNVvMAGKSGAVYKQNNEIVSV-PYsslfAKNETVSIPHFQSYVCYPNRDS-LSYI-GLYdlQkAHTFV 245
4INA_A       249 FFXTFGQSYLTHXRCLENVGXLRIDei--evNGc---------------------------------------------- 280
WP_012793044 245 RATLRYPDFCEGWGTLVKLGLTDDTkki-qtDNmtfyewtsqhidqdtsisheenianyl----gisakskilrqlkflg 319
WP_013768666 245 RGTLRYEGFCAAWDALIQIGLTDADfpilhsGEityhelmdayvdpygggslkdrtaeml----gedinspvmkklewlg 320
WP_014162420 242 RGTFRYPGWCELIAKMNDLGLFETTem--dlKEltyrdfmakilntgkanveeklcsalg-----reafssvflklkwlg 314
WP_008585121 245 RATLRHNDFCTGWQFIVLAELTNPLdie-miDSlkdksigewfvaclnfytksatfpaflnryvaaqerqlitqlfeylg 323
WP_015265636 246 RGTLRRAGFCKSWDVLVQLGLTDDSfemdlpHDftmrmftnaflpydpvhrleekiqrll-----pwvdkeiieklawlg 320
WP_057952576 241 RGTFRHQSWCATLDAIKRLNLIETDeh--dfTGktyaefvkdmaglkgadikqaiaekld-----ipkdadaiksiewlg 313
WP_067542603 245 RGTLRRQGFCRAWDVFVQLGMTDDSyqlslpEHttyrqflnaflpwdeaksveekladli-----pefdfptfeklqwlg 319
WP_006927860 242 RGTLRNVGHCETWNYFKKLGLFNQEfkv-dfAKtsvkqaiarlinsdgknltkdianfln-----ipeysvtlkklewlg 315
WP_076380647 246 RTTLRHPHFCIGWRFIVDWQLTNEEkvy-atDGlsiqgfflqhfsslhidsayelkp----------dtiiynqlvylgl 314
4INA_A       281 ----------kVVPIQVLKALLPDpaslASRTkGKTNIGCYIKGI--K-EGKaRTIYIYNVCDHEscyrevnaqaISYTT 347
WP_012793044 320 llnsetihlgeQTNASVLQHIVESklgmEVTDkDMIVMTHEIEFE--R-RGM-STRLHSYMIAQGedni---rtaMAKTV 392
WP_013768666 321 vfskkkiklpnATPALILEHLLRDkwklKPTDkDMVVMHHEIEYE--K-KGE-KRLRTSTMSKKGvnae---dtaMAQTV 393
WP_014162420 315 llseekipfetGSPRSVVASLFHKrlvfSKGEkDLVLMEHRYVASfpK-ENT-KKLITSTLICTGsvde---dtaIAKTT 389
WP_008585121 324 lfsdekipleaKSSADILQYLLETrlalASTDkDMILMIHEIEFMn-R-DQQ-PGRLSSSLVVKGenal---qtaMAKTV 397
WP_015265636 321 lfdhtplslfkGSPAVILQAILEDkwnlSPSDkDMVVMQHQLETVs-P-SGT-KKSITSSMIIKGenhe---ytaMAKTV 394
WP_057952576 314 llddkdmnrqkDTAFEVTSDLMIEkmwmNDKDrDMVAMQHVFLVK--RnDGE-KEVIKSRLLDFGdpqg---ytsIARTV 387
WP_067542603 320 ffesiplpktqGSPAQLLQYILEQnwalESEDqDMIVMQHQFEIQ--T-ERG-IKKITSSLVEIGkner---htaMAKTV 392
WP_006927860 316 llsdeklplgeASIFDMFAHILQHklvyEEGEvDLLIQHHEFIAEy-P-DGK-REKLTSTLVDTGiphg---dtsMARTV 389
WP_076380647 315 ndnntlinkglCSAADVLQWLLETrlplLPDDkDLVVMMHELKYT--I-QNQ-SFRAKSYLVVEGkdds---ytaMAQTV 387
4INA_A       348 GVPAXIGAKLXLEGKWSGKGVFNXEE--LdpdpFXDelnKQGLPWE 391
WP_012793044 393 GLPLGIMAKLILQDKVTLKGLHIPITpdIyn-pVLKeleEFNIRFE 437
WP_013768666 394 GLPMAIFVKLVVEGKIKSRGVQIPVMkeVye-pVLEeleQYGIVFH 438
WP_014162420 390 GIPPAIGAMLILQGKIKATGVHAPVLpeIye-pSLKlleKEGITFT 434
WP_008585121 398 GLPLAIATKLILSGTITTKGLQIPILkeIye-pVLAelgKKGIRFV 442
WP_015265636 395 GLPLAAAVDLFLEGEIPLRGLHLPIKeeIyl-pVLKllaNNGITFD 439
WP_057952576 388 ALPAAVAVDRILQDKIKLAGVYRPVVkeIye-pVMDeleTMDIKMV 432
WP_067542603 393 GLPLAIAVDLFLQQKINLRGLHLPVIpeLfd-pILKqleSFGIRFT 437
WP_006927860 390 GLPAAIATRLIVEGKINLKGVHIPVLpdIye-pILAeleAMNIKLV 434
WP_076380647 388 GLPLGIAAKLILEGVIRLTGLHIPLSpvIyh-pVLSeleTEGIRFT 432
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