Conserved Protein Domain Family
PAC1

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pfam16094: PAC1 
Proteasome assembly chaperone 4
PAC1 is a family of eukaryotic proteasome assembly chaperone 1 proteins in eukaryotes that promotes assembly of the core 20S proteasome as part of a heterodimer with PAC2.
Statistics
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PSSM-Id: 465018
Aligned: 13 rows
Threshold Bit Score: 409.867
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003763396   2 AATFFGEVVKVRSRAV-TEEEEEEEeepwarDNLEDKEVRQELEKKREVEVL-QTQTKVSLEIpllEQYPCSKFIIAIGH 79 
Q5F3H4         1 MATFFGEVVVAPSRAG-VDDEEETE------ETAEDREIRRELQEKREITALwTPGAAGSPAE---EPLRCSRFIVAVGH 70  chicken
O95456         2 AATFFGEVVKAPCRAG-TEDEEEEEeg--rrETPEDREVRLQLARKREVRLL-RRQTKTSLEVsllEKYPCSKFIIAIGN 77  human
XP_003214800   1 MATFFGEVVAARSRAGlDEEEEEEEaaaqrqETPEDRQIRLALQEKREVHLVwNPGLKASTE----EQLPCSKFIVAVGQ 76 
XP_002599070   5 LGCGYGDLVLASSRAV-DDEEEEEEa----sQKPS-----------PSAVLRwSTQAKQEISEspnDCIECSALIVAIGP 68 
XP_011435879   1 MATFFGEILPVISRAV-DDDDDDESf-----ENLE-----------TYVKIKwKKEAQEEMELtndKKLQANAFVLAVGP 63 
XP_003979003   1 MATFFGEVLSVFSRAV-EEDEDDLS------DNEEDEQIRRELEEKRVVHLHwNPEVTECLKSg--NKLKCSDFILAVGP 71 
XP_004076825   1 MATFFGEVLSVCSRAV-EEEDEDFV------ENEEDEEIRRELEKKREVNLLwNPETSQSLASg--NKLQCSDFFLAVGH 71 
XP_006627837   1 MATFFGEVLSVYSRAV-EEDEDELEd-----ESEEDVQIRREIENKREVHVHwSSEITKSTD----KPFQCSDFIIGVGH 70 
Q6DG91         1 MATFFGEVLSVYSRAV-EEDEYEDMt----nENEEDEQIRREIEEKRSVEVCwLLGSQD-------GPLQCSDLIIGAGP 68  zebrafish
XP_020496170   1 MATFFGEVLSVYSRAV-EEDEEDLQ------ENEEDEQIRRELEEKREVHLQwSPEVSESLKSg--NKLQCTDFILAVGH 71  ballan wrasse
XP_006002592   1 MATFFGEILPVFSRAV-DDSEDEAVl----eEDEEDQEIRRELAKKrEVYVEwNPEISSSTKNsseGRLQCSNFILAVGD 75  coelacanth
KAE8621440     1 MATFFGEVQSVFSRAV-DEDDEEEEg----eEEEEDREIIAELDRKREVHVTwNPEVTAAIESspnRRLPCSSVILSVGD 75  tropical clawed...
XP_003763396  80 NAVAFLSSFVMNSGTWEEIGCT--KLWNEWCRTRDTANl--sPTDAFCVFYRLKSDPTIFLCQCSCYVAEDQQYQWLEKV 155
Q5F3H4        71 NAVAFLSAFILDSVCWKIVGAV--KLWNEWCQTTNATSv--lPTDSFCLFYQLISDPTVLLCQCSCYVAEDQQFQWLEKV 146 chicken
O95456        78 NAVAFLSSFVMNSGVWEEVGCA--KLWNEWCRTTDTTHl--sSTEAFCVFYHLKSNPSVFLCQCSCYVAEDQQYQWLEKV 153 human
XP_003214800  77 NAVAFLSSFVLSSDSWEVVGSV--KLWNEWTRTSNTTKf--lPADSFCLFYRLISDPTVLLCQCNCYVAEDQQFQWLEKV 152
XP_002599070  69 VATGFIHTYLLHQET-EILGMIgsGLLEDTCNTFEQTS----PADATCFLHRLMSAPSVIVCQCNVDVPPEMMFSWTQQL 143
XP_011435879  64 AATGFTQTYV-THKNYEIIGAMfcGMKEDDVNTFGQMS----PTDKTCYIYRKCDYPSALVCECNYDIRPEYAHSFVNQL 138
XP_003979003  72 NAARFLSVHALTSANWDTVGHS--SLWNERNQTTTGQT----SVEPACVFHRQKDNPSVLICQVTCYIAEDQLFQWTEKV 145
XP_004076825  72 NAASFLSAYVLSSSNWDAVGRA--SVWNERSRAVAGQS----SEESACVFYRHKDIPSVLICRVTCYIAEDQLFQWTEKV 145
XP_006627837  71 NAAGFLSAFVLSSGSWEAVGSA--SLWNERSRGSSQP-----AGEPSCRFYRSAGCSSVLICLCTCFVAEDQLFQWTEKV 143
Q6DG91        69 NASGFIRAYLLSTVGWTAVAWL--SFWNERSRGSERPTvvpgPGEPSCVLYRLESCPTVLICQCQGFVAEDQLFQFTEKV 146 zebrafish
XP_020496170  72 NAARFLSVYVLTSANWDAVGHA--SVWNERSRAVSGQT----SEESACVFYRQKDNPSVLICQVTCYIAEDQLFQWTERV 145 ballan wrasse
XP_006002592  76 NAVGFLQCYILSSGNWEEVGSV--HVWNERCKDLTATNqk-lPANSSCVLYQLSTDPTVLACQCGCYVAEDQLFQWTEKI 152 coelacanth
KAE8621440    76 NATGFVSSYILSSGSWEVCGSI--TLWNERCRDCNARKds-lPAPSSCTFYRSITDPTVLLCQCNSYIAEDQLFQWCEKV 152 tropical clawed...
XP_003763396 156 FGSSPNRNLQITILTSRHVTDYKTPESSCNLPSPFLKALKTQTFQDAACCTLLEQPNIVHDLPAAVLSYCQVWRIPAILY 235
Q5F3H4       147 FGHIGKEGLQVTILSTCPVAEYKTQESTLTLPSPFLKALKTKEFKEEVCCPLLEQPNIVRDLPAAVLSYCQVWQIPAVLY 226 chicken
O95456       154 FGSCPRKNMQITILTCRHVTDYKTSESTGSLPSPFLRALKTQNFKDSACCPLLEQPNIVHDLPAAVLSYCQVWKIPAILY 233 human
XP_003214800 153 FGCLQKTNLTVLVLSSCSVTDYKTPESIITLPSPFLKALKTKEFKDQLCCSLLEQPNIVRDLPAAVLSYCQVWHIPAVLY 232
XP_002599070 144 FSCINIHNTYVGVLASAPVSEFRSSVSLSDVTVPFLRGLKTNQFHGKPVCPYLEQPNTAKGLPASVLTHCQVYRVPAVLY 223
XP_011435879 139 MSCLNLCEGHVVIFGSTFTSEYKSDVPTSDMNPPFMRALKTASFLGTPMAPYLEQPNVATGLPAQMLTYCHIHKLNAVLY 218
XP_003979003 146 FDCLQHRQLNVTVLSDSSVAEYKAADYLHCSSAPFLRSLHSSTYNGKSVCPSLEQPNIFTGLPAAVLSHCEVHRIPAVVY 225
XP_004076825 146 FDCVQHRGLNVTVLSDSSVADYKTENYLSSSSAPFLRSLHTAAFSDQPVCQSLEQPNIVTGLPAAVLNHCQVHCIAAVVY 225
XP_006627837 144 FGFIQTRGLQVLVLSDASVSEYTTADPVSASPVPFLRALKSSAYQDRVHCPMMEQPNIVTCLPAAVLSHCQVHQIPAVLY 223
Q6DG91       147 FSCVQTRDLNVTILSDCSSADYKTSDYLSGSSTPFLRCLKTSTYTHTVTCPPLEQPNICSGLAAAVLSHCQVHQISAVLY 226 zebrafish
XP_020496170 146 FECLQLRELNVTVLSDSSVAEYKTADYLCCSSAPFLRSLHTGAFSGKPVCQSLEQPNIVTGLPAAVLNHCEVHRIATVVY 225 ballan wrasse
XP_006002592 153 FNSIQTKGVTVTVLSSWPVAEYRTAAPVTSLQVPFLQALKTRDYSGTICCPLLTQPNVVQGLPAAVLSHCQVWQIPAVLY 232 coelacanth
KAE8621440   153 FGSLEKSGLNVTVLSTCPVSEYKTPESTYSLPVPFLKALRTSEYREEVPCPLLEQPNIADGLPAAVLTYCQVWQIPAVFY 232 tropical clawed...
XP_003763396 236 LCYTDVMKLDLVTVEAFKPILGSESLKGLVKNVSHGT-EILKKLVTRNEIQSNIYT 290
Q5F3H4       227 QCYTDIIKLDAVTIEAFKPLLSSKPLKNLVKDISEST-KILKKLLTTGETHNNIYI 281 chicken
O95456       234 LCYTDVMKLDLITVEAFKPILSTRSLKGLVKNIPQST-EILKKLMTTNEIQSNIYT 288 human
XP_003214800 233 QCYTDVLKLDLVTVDAFKPVLSSRILKTLVKDTARNT-ELLIKLVTTNETH-NIYT 286
XP_002599070 224 MCYSDSIYVEIPAIKAFLPVLKGTPFRDIVQENPHAD-ISLRKLVELRALQNNLYT 278
XP_011435879 219 MCYTDSIHLDFATLKTFQPLIESTPVKYMREENKKAS-ETLKKIVDLHTKHSTLYM 273
XP_003979003 226 QCYSDVLGADSVTMETYNPVLTSLG-KSIQLDPAPST-DVLRKFSRTSNIQSNLYI 279
XP_004076825 226 QCYSDVIGPDSVTMETYMPVLTKLG-KVMQLDQPPTT-DVFRKFVRTTDIQSNLYI 279
XP_006627837 224 QCYSDVVSPDTVTMETYKPALPCLS-KLVTLDSSPSI-DVLRKVVKSSESQSNLYT 277
Q6DG91       227 QCYSDVLHPDSASMQMFAATLSSV----LKLEQSLSA-DVLQRVTRVSEIQSNLYT 277 zebrafish
XP_020496170 226 QCYSDVIGPDSVTMETYKPALTKLG-KSIQLDPSPST-DVLRKFAR-NNVQSNLYI 278 ballan wrasse
XP_006002592 233 QCYTDTIKLDLVTVEAFRPVVSSKNLSPLV-QDSPKReELLKQLASINEAESNLYt 287 coelacanth
KAE8621440   233 RCYTDLSKLDSITIDAFRPLLSCQRMSRLAADSAKIQ-ETLRKtvksseiqsnlyi 287 tropical clawed frog
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