3MOG


Conserved Protein Domain Family
PaaC-3OHAcCoADH

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TIGR02279: PaaC-3OHAcCoADH 
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3-hydroxyacyl-CoA dehydrogenase PaaC
This 3-hydroxyacyl-CoA dehydrogenase is involved in the degradation of phenylacetic acid, presumably in steps following the opening of the phenyl ring. The sequences included in this model are all found in aparrent operons with other related genes such as paaA, paaB, paaD, paaE, paaF and paaN. Some genomes contain these other genes without an apparent paaC in the same operon - possibly in these cases a different dehydrogenase involved in fatty acid degradation may fill in the needed activity. This enzyme has domains which are members of the pfam02737 and pfam00725 families.
Statistics
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PSSM-Id: 188207
Aligned: 4 rows
Threshold Bit Score: 793.373
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3MOG_A     1 MSLNVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIH 80  Escherichia coli K-12
AAC24331   3 ALASTVQVAVIGAGAMGAGIAQVAAQAGHPVKLYDNRPGAAAQAVAGIERQLARLVEKGKLRAVEREMISLRLCPVDTLE 82  Pseudomonas putida
P76083     1 MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIH 80  Escherichia coli K-12
AAG28966   3 ALTRDVKIVVIGAGAMGSGIAQVAARAGHTVYLYDGRSEAIAAGRAAIEKDLKFLVAKNRLDGAEATATLERVVPVAALA 82  Azoarcus evansii
3MOG_A    81 ALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLA 160 Escherichia coli K-12
AAC24331  83 ALADAGLVIEAIVENLQVKQALFSQLEALCTADCIIASNTSSLSITSLAAGLARPQQVVGMHFFNPAPLMALVEVVSGLA 162 Pseudomonas putida
P76083    81 ALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLA 160 Escherichia coli K-12
AAG28966  83 EAADAGLAIEAIVENLDVKRKLFAELESLLGADAIIASNTSSLSINAMAAGLARPGRLAGLHFFNPAPRMALVEVVSGLT 162 Azoarcus evansii
3MOG_A   161 TAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQD 240 Escherichia coli K-12
AAC24331 163 TEPAVAACIYDTAQAWGKQPVHTRSTPGFIVNRVARPFYAESLRLLQEGAADCASLDALLRDAGGFRMGAFELTDLIGHD 242 Pseudomonas putida
P76083   161 TAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQD 240 Escherichia coli K-12
AAG28966 163 TDREVAETLYATARAWGKVPVHAASTPGFIVNRVARPYYAEALRVLAEHEAEPATLDAILREGCGFAMGPFELMDLIGHD 242 Azoarcus evansii
3MOG_A   241 VNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSDSFSP---------------- 304 Escherichia coli K-12
AAC24331 243 VNYAVTCSVFDAFYGDFRFQPSLVQKELVDAGRLGRKTGQGFYSYAEGAERPAPVELHSSTKAEacviegqlgvlqplve 322 Pseudomonas putida
P76083   241 VNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSDSFSP---------------- 304 Escherichia coli K-12
AAG28966 243 VNFAVTKSVFEAYFCDRRFAPSPFQQELVAAGRLGRKSGRGIYEYGELAAKAVPQDEAPQDGEPrvtvvgdigaaaplla 322 Azoarcus evansii
3MOG_A   305 ------MKVEKKSD-----GVTEIDDVLLIETQGETAQALAIRLARP-----VVVIDKMAGKVVTIAAAAVNPDSATRKA 368 Escherichia coli K-12
AAC24331 323 rlrqngIVVTQRAGs----GVIQVGDATLALSDGRLASQRAREDGLRnlvllDLALDYSTASRIAISWSGDTTESARDQA 398 Pseudomonas putida
P76083   305 ------MKVEKKSD-----GVTEIDDVLLIETQGETAQALAIRLARP-----VVVIDKMAGKVVTIAAAAVNPDSATRKA 368 Escherichia coli K-12
AAG28966 323 rleaagIEVRRESGmhgkrGWMQIGAARVALTDGRTATLRAAEERQPnlvlfDLCLDYSTSTRIALTRADQCGLGALRVV 402 Azoarcus evansii
3MOG_A   369 IYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYG-PLAWGAQLGWQRILRLLEN 447 Escherichia coli K-12
AAC24331 399 VALLQRAGLKVTAVADLPGLVVLRTVAMLANEAADAVLQGVGSAADIDLAMRAGVNYPCG-PLAWATNIGIAHTLRVLDN 477 Pseudomonas putida
P76083   369 IYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYG-PLAWGAQLGWQRILRLLEN 447 Escherichia coli K-12
AAG28966 403 TGTFQKAGFKVSVIDDVAGLIALRTVAMLANEAADAVLQRVASARDVDTAMRHGTNYPKGgPLAWADQLGAGFVVEVLAN 482 Azoarcus evansii
3MOG_A   448 LQHHYGEERYRPCSLLRQRALLESGYES 475 Escherichia coli K-12
AAC24331 478 LQRSYGESRYRPSLLLRRCEAKGGTLHD 505 Pseudomonas putida
P76083   448 LQHHYGEERYRPCSLLRQRALLESGYES 475 Escherichia coli K-12
AAG28966 483 LQEHYGEERYRVSPLLRRKACNGEAMYD 510 Azoarcus evansii
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