1L5J


Conserved Protein Domain Family
AcnB

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COG1049: AcnB 
Aconitase B [Energy production and conversion]
Aconitase B is part of the Pathway/BioSystem: TCA cycle
Statistics
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PSSM-Id: 440670
Aligned: 87 rows
Threshold Bit Score: 1613.76
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1L5J_A         1 MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEE-FLLDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAKSP 79 
WP_011365887   1 MIEAYLAHEAERKAQGIPALPLNPEQTADLCNLLQNPPAGKEE-FLLNLLKERVSPGVDPAAKVKAAFLAEIVKGTKKSP 79 
WP_011498480   1 MIEAYLIHEEERKAQGIPALPLNPEQTSELCELLQNPPAEQEE-FLLHLFTERISPGVGPAAKVKADFLGNILTGDASSP 79 
WP_011735582   1 MIQEYLHHEQERARQGIPPLPLSAEQTARLCALLTAPPSGREE-FLLTLLERRVPPGVDPAAKVKAGFLTNIVSGALQSP 79 
WP_012632657   1 MIEAYLKHEAERKAQGIPPKPLDPEQTKGLVKLLEAPPKGQEA-FLLGLLRDRVSPGVDPAAEVKAKFLADVVSGAKTCP 79 
WP_013507048   1 MIEAYLQHEKERSAQGIPPKPLTPEQTASVCEMLQNPPAGKEE-FLLALLRDRVSPGVDPAAEVKADFLAKIAKGQASSP 79 
WP_013451110   4 IFDQYLKHVEERKAMGIPPLPLSPEMTAEVCKALENPEKGKEE-FLLSLLRDRVSPGVDPAAEVKANWLAKVVRGEVKSP 82 
WP_011139059   3 FLAEYQAHVLERAKENIPPLPLNAEQVKAVIEGLLHPSNEEIE-TFKELLSHRVSPGVDEAAKVKAEFLDKIAKGTLACE 81 
WP_013885864  68 MLKEYEDHVQEREKLGIPPLPLSPELTKEVCEKLENPANQKEQdYLLYLLKERVAPGVDPASKVKAEWLNKVATGEVKSP 147
WP_128467469   1 MMQDYLKHVEERKAQGIPPLPLSPEFTAEVCKMLENPAKEQAD-FLKELIVNRVSPGVDPAAEVKAAWLERVAKGAVKCP 79 
1L5J_A        80 LLTPEKAIELLGTMQGGYNIHPLIDALD-DAKLAPIAAKALSHTLLMFDNFYDVEEKAkAGNEYAKQVMQSWADAEWFLN 158
WP_011365887  80 LVSKVDAIRILGTMIGGYNVGPLVEALK-DAELAEEAACALSRMTLVYDGFDQVVELS-KSNAAAKKVLESWANAEWFTN 157
WP_011498480  80 LIDKKEAIGILGTMIGGYNVKYLIEALG-DSEVADEATCALSGITLVYEAFDEVLELS-ETNEAARKVLESWANAEWFTS 157
WP_011735582  80 LLTPFDAIRILGGMLGGYNVAPLVAALS-DPELVGEAADQLSRITLVHGAFDQVAALVrEGNQAASRVMRSWAEGEWFTR 158
WP_012632657  80 LVSRAQAVELLGTMMGGYNVPPLVAALK-DPELAAAAAKALSHTTYVYGAFDDVLALS-KTNAAAKSVVDAWAKAEWFSS 157
WP_013507048  80 VISKQDAVKMLGTMLGGYNLQYLVDLLQ-DSSLANEAAEALKGLVLIFDKLESINKLA-ASNPAAKSVMESWANAEWFTR 157
WP_013451110  83 LVSKEDAIFMLGTMIGGYNVAPLVEALK-DPSLAKSAANALKNVILVYGAFDEVAELS-KTNQYAKEVIESWANGEWFTS 160
WP_011139059  82 AISPKEAISLLGTMLGGYNIKPLIEALSlEEDLAKEAVEKLKETLLVYEGFNEILALS-KYNPYAKEILESWAKAEWFTR 160
WP_013885864 148 AVSAEDAVDILGTMLGGYNVQYLVELLK-DDQLGKKAAEALKTTILVYDAFDDVLKLS-KSNSNAKEVITSWAEGEWFTS 225
WP_128467469  80 VITKKDAVFFLGTMLGGYNVKPLVDLLT-DAELGADAAEALKQTILIYGSFEDVLALS-KSNANAKAVIQSWADAEWFTS 157
1L5J_A       159 RPALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGiepdqpgvvgPIKQIEALQQKGFPLAYVGD 238
WP_011365887 158 RPGVPETIKVKVFKVEGEINTDDFSPAGDAWSRPDIPLHALAMGKTRFPN----------RLKDIADWRAAGHQVAFVGD 227
WP_011498480 158 RQAIPETITVRVFKVDGEINTDDFSPASAAWSRPDIPLHALEMGTTRFPG----------GIEEIAKWRGEGHEVAFVAD 227
WP_011735582 159 RAPLPATIRLKVYRVQGEINTDDFSPAGDAWSRPDIPLHALVMGRRRFPD----------GLATMAAFREEGCRIAFVGD 228
WP_012632657 158 RPGVPETIKVKVFKVDGEINTDDFSPAGDASTRPDIPLHALAMGKTRFPG----------GLKTIAEFRAQGFQVAFVGD 227
WP_013507048 158 KPDFPAEIKVKIFRVDGEINTDDFSPASEAWSRPDIPLHALCMGNKRFPG----------GLEQIAKMRAEGFSVAFVGD 227
WP_013451110 161 KPDLPKEIKLKVYKVDGEINTDDFSPAKHAFSRPDIPLHALAMGETRFPG----------GIQEIANFRAEGYQVAFVGD 230
WP_011139059 161 RPPLPHKILLTVFKIEGETNTDDLSPASDAFTRSDIPLHAQSMLKNRTQN----------AFVRIEELKKKGFPLVYVGD 230
WP_013885864 226 KPDFPKEMKLKVYKVEGEINTDDFSPAKHAWSRPDIPMHALAMGESRFPE----------GNETIKKFREEGYKVAFVGD 295
WP_128467469 158 KPEFPKSFKLKIFKADGETNTDDFSPAKHAWSRPDIPLHALAMGETSWPQ----------GNTTIDKFREEGFEAGFVGD 227
1L5J_A       239 VVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRN 318
WP_011365887 228 VVGTGSSRKSACNSVLWHMGQDIPAVPNKKTAGVIIGGVIAPIFFNTAQDSGALPLKADVTKMNDGDVITINTAKGEISN 307
WP_011498480 228 VVGTGSSRKSACNSVLWHIGKDIPHVPNKRRDCVIIGTAIAPIFFNTAEDSGALPLQMDISKLQHGDIITINTVKGEVTD 307
WP_011735582 229 VIGTGSSRKSACNSLLWAIGEDIPGVPNKRGGGVIIGGVIAPIFFNTAQDSGALPIRAEVGALSTGDLIVVDTVRGIISD 308
WP_012632657 228 VVGTGSSRKSACNSVLWAIGEDIPFVPNKRRGGVIIGGVIAPIFFNTAQDSGALPIRTDVTKLKTGDVVVIDTKKGEVRT 307
WP_013507048 228 VVGTGSSRKSACNSLLWHIGEDIPFVPNKRRGGVIIGNAIAPIFFNTAQDSGALPLRCDVSKLKMGDVVTINTVEGTIKN 307
WP_013451110 231 VVGTGSSRKSACNSLMWHIGEDIPFVPNKRRGGIVIGGLIAPIFFNTTQDSGGLPIMCDVTGMKTGDVIIIDTVKMEIRK 310
WP_011139059 231 VVGTGSSRKSACNSLVWHMGHEIPFIPNKKAGGVVIGTSIAPIFFNTCEDSGTLPIVADASKLNEGDVIALYPYEGRIEK 310
WP_013885864 296 VVGTGSSRKSACNSVMWHIGEDIPNVPNKRNAGVVIGGLIAPIFFNTTEDSGGLPVMCDVTGMNTGDVIILDFEKGEVRK 375
WP_128467469 228 VVGTGSSRKSACNSVMWKIGQDIPFVPNKRRGGVILGGVIAPIFFNTTEDSGGLPIICDVNNIKTGDVVIVDTEKCEVRD 307
1L5J_A       319 hETG-ELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVA-ESDRGFSLAQKMVGRACGVK 396
WP_011365887 308 -DKG-EVISTFKISPNTLADEFRAGGRIPLIIGRAITEKARKALGLGDTDVFTKPVNPApKAGQGYSLAQKMVGKACGVA 385
WP_011498480 308 -EEG-NVLSTLYLNPNTLPDEYRAGGRIPLIIGRSLTTRTREVLGLPETDIFVKPDNPIpEPGQAYSLAQKIVGQACSVD 385
WP_011735582 309 -EQGaNVLSRFSLAPATLADEFRAGGRIPLIIGRALTDRARSFLGLPGSTLFTLPDNPVpEPGQGFTLAQKMVGAACGVG 387
WP_012632657 308 -EQG-EVLSTFKLEPVTVPDEFRAGGRIPLIIGRALTDKARKALGLKEIDLFAVAKNPQpKAGQGYSLAQKMVGKACGIA 385
WP_013507048 308 -EAG-ETLSTFKVNPGTLKDEYRAGGRVPLIIGRSLTNSARKLLGQGESDLFIQPDNPQpKAGQGYTQAQKIVGKACGLP 385
WP_013451110 311 -ENG-EVLTKFELKPATIRDEFRAGGRLNLIIGRALTNKARAFLGLGESDLFVKAQNPVpKPGQGYTLAQKIVGKACGLP 388
WP_011139059 311 --AG-EGVATFNLTPNTLSDEIRAGGRINLIIGRGLTAKAQEALGIKEDDLFIKPQNPQ-GKARGFTLAQKMVGRACGVE 386
WP_013885864 376 -DDG-TVLTNFELKPKTLRDEYKAGGRLNLIIGRSLTNKARSALGMDESDLFIKPDNPKpKPGQAYSLAQKIVGKACGEA 453
WP_128467469 308 -EAG-KVISTFKLSPATIKDEYRAGGRLNLIIGRQLTVKARKALGLPESTVFTATVNPVpKKGQGFTLAQKIIGKACGVE 385
1L5J_A       397 GIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGD 476
WP_011365887 386 GILPGTACEPKMTTVGSQDTTGPMTADELKELACLKFLSPMFMQSFCHTAAYPKPADVKMHKNLPGFIIERGGVPLKPGD 465
WP_011498480 386 GVLPGTACEPIMTTVGSQDTTGPMTTDELTELACLKFQAPMFMQSFCHTAAYPKLTDVKMHRTLPDFVSDRGGVSLNPGD 465
WP_011735582 388 GVLPGSACQPVMTTVGSQDTTGPMTADELKELACLSFQAPLVMQSFCHTAAYPKLSDLAMHRTLPSFITQRGGVSLRPGD 467
WP_012632657 386 GALPGGYYEPRMTTVGSQDTTGPMTADELKELACLKFQAPMVMQSFCHTAAYPKPADVKMHGSLPSFIQQRGGVALRPGD 465
WP_013507048 386 GVLPGTACEPKMTTVGSQDTTGMMTADELKELACLKFQADMYMQSFCHTSAYPKPADVSMHKNLPNFVAERGGVALRPSD 465
WP_013451110 389 GVLPGTACEPKMTTVGSQDTTGPMTADELKELACLRFQADLFMQSFCHTAAYPKPADVKMHKTLPSFVIARGGVSLKPGD 468
WP_011139059 387 GIAPGTYCEPRVATVGSQDTTGAMTRDEIKELASLGFSADFVLQSFCHTAAYPKPSDVKLHATLPQFISTRGGVSLRPGD 466
WP_013885864 454 GVLPGTSCEPKMTTVGSQDTTGPMTADELKELACLKFQTDLFMQSFCHTAAYPKSADVKMHKSLPDFITEREGVALKPGD 533
WP_128467469 386 GVLPGTACEPVMTTVGSQDTTGPMTRDEITELACLEFQASMFMQSFCHTAAYPKKADVAMHKSLPDFVTLRKGVALRPGD 465
1L5J_A       477 GVIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLY 556
WP_011365887 466 GVIHSWLNRLLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAGAMGFMPLDMPESVLVRFKGKLNPGITLRDAVNAIPYW 545
WP_011498480 466 GIIHSWLNRLLVPDTVGTGGDSHTRFPIGISFPAGSGLVAFAGALGFMPLDMPESVLVRFSGKLNSGITLRDVVNSIPYY 545
WP_011735582 468 GVIHSWLNRLLLPDRVGTGGDSHTRFPLGISFPAGSGLVAFAAAMGFMPLDMPESVLVRFSGSLNSGITLRDAVNAIPLQ 547
WP_012632657 466 GVIHSWLNRLLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFGAALGFMPLDMPESVLVRFKGKLNPGITLRDVVNAIPYW 545
WP_013507048 466 GVIHSWLNRLLIPDTVGTGGDSHTRFPIGISFPAGSGLIAFAGALGFMPLDMPESVLVRFKGKLREGITLRDVVNAIPYY 545
WP_013451110 469 GVIHSWLNRLLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAGALGFMPLDMPESVLVKFKGKLNPGITLRDVVNAIPYV 548
WP_011139059 467 GVIHSWLNRMILPDTVGTGGDSHTRFPVGISFPAGSGLVAFAAVTGSMPLDMPESILVRFRGELQKGITLRDLVNAIPYY 546
WP_013885864 534 GVIHSWLNRLLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAGALGFMPLDMPESVLVKFKGELNPGITLRDVVNAIPYF 613
WP_128467469 466 GVIHSWLNRLLLPDTLGTGGDSHTRFPIGLSLPAGSGLVAFAGALGFMPLDVPESVLVKFKGKFNPGITLRDAVNAIPYW 545
1L5J_A       557 AIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYG 636
WP_011365887 546 AIKQGKLTVPKKNKINIFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAGCIQLSKESVATYLRSNVALMKKMIADGYQ 625
WP_011498480 546 AIQQGLMTVPKKNKINIFNGRILEIEGLPDLTAEQAFELTDSAAERSAAAGCIQLDEKPVATYLRSNVALMKKMIGNGYS 625
WP_011735582 548 AIREGLLTVPKQNKVNIFSGRILEMEGISDLSVEQAFELTDSAAERSAAAGCIQLSEERVAEFLRSNVALMKRMVNEGYQ 627
WP_012632657 546 AIKQGLLTVPKKNKKNVFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAAAVDLSEKSVATYLRSNVALMRKMIADGYG 625
WP_013507048 546 AIKQGLLTVPKAGKINCFNGRILEMEGLPELSVEQAFELTDAAAERSAAAGCIKLSEASVVAYLKSNIALMEQMIKDGYQ 625
WP_013451110 549 AIKQGLLTVAKKGKKNIFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAATIKLSENSVADFLKSNIALMKEMIAEGYQ 628
WP_011139059 547 AIKRGLLTVEKQGKKNIFSGKILEIEGLPRLKVEQAFELSDASAERSAAACTVRLDKEPIIEFLRSNIRLIEAMIEAGYE 626
WP_013885864 614 AIQEGLLTVEKAGKKNIFNGRIVEMEGLPDLTVEQAFELTDASAERSAAGATIKLSEESVAEFLKSNIALMKKMIEDGYQ 693
WP_128467469 546 AIKQGLLTVPKQNKKNIFNGRILEMEGLPDLTVEQAFELTDATAERSAAGGTIKLSEKSVSGFLRSNIALMKKMIAAGYR 625
1L5J_A       637 DRRTLERRIQGMEKWLANPELLEADADA----EYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQG-----EKIDEVFI 707
WP_011365887 626 DAQTLQNRIDAVNEWLKNPQLLEADKNAvetgAYADVIEIDLAEITEPILACPNDPDDVKLLSDVAG-----TPIQDVFL 700
WP_011498480 626 DAQTLQKRIEAVEEWLEDPKLLKADPNA----DYAAVIGIDLADIKEPILACPNDPDDVKLLSEVAG-----TPIQDVFI 696
WP_011735582 628 DAESLLRRIRDVELWLDNPLLMRADKNA----SYAARLRVDLSEIREPILACPNDPDDVRLLSEVAG-----TPIQDVFI 698
WP_012632657 626 DKAALEARIAAVEAWLAKPELLRADRNA----DYAAVIEIDLAEITEPILACPNDPDDVKLLSDVQN-----TKIDDVFL 696
WP_013507048 626 DAKTLEKRIADVKEWLKNPRLIEADSNA----EYAEIIEINLDEMTEPIVACPNDPDDVKLLSEVAG-----TKVDDVFI 696
WP_013451110 629 DAETLKRRIAACEKWLEKPELLSRDENA----EYAAVIEIDLSEIKEPILACPNDPDDVKLLSEVAG-----DKIDEVFI 699
WP_011139059 627 SQETLARRAQKMRAWCENPELLEPDSDA----EYAEIIEIDLNEITEPILACPNDPDDVATLSEVLNnparpHRIDEVFV 702
WP_013885864 694 YADTLKKRIEDCEKWLEKPALLERDKDA----EYAAVLEIDLNDIKEPILACPNDPDDVKLLSDVAG-----TNIDEVFV 764
WP_128467469 626 HADTLKKRIEDAEKWLANPVLLERDENA----EYAAVIEIDLAEITEPILACPNDPDDVKLLSEVAG-----NKIDEIFI 696
1L5J_A       708 GSCMTNIGHFRAAGKLLDAhKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVS 787
WP_011365887 701 GSCMTNIGHFRAAAEIWRGlKFNPSVRTWICPPTRMDQKQLKDEAYFSVYSAFGARIEIAGCSLCMGNQARVPDGVNMFS 780
WP_011498480 697 GSCMTNIGHFRAAAEIWRDqKFNSDVRTWICPPTRMDQAKLREESVFSVYGQVGARIEIAGCSLCMGNQARVPDESTVFS 776
WP_011735582 699 GSCMANIGHFRAAAEIWRGqTFNPQVRIWLCPPTRMDEQQLRDEACFQVFGAVGARMEMPGCSLCMGNQARVPDGVTVFS 778
WP_012632657 697 GSCMTNIGHFRAAGEIWKGqKNTGLVRTWLCPPTRMDQQELRDEAYFSVYSQIGARIEIAGCSLCMGNQARVPDGVNVYS 776
WP_013507048 697 GSCMTNIGHFRAAAKIFEGeKFNPGVRTWLTPPTRMDYKKLMAEATFAKFSAIGARIEQPGCSLCMGNQARVPDKVTVFS 776
WP_013451110 700 GSCMTNIGHFRAAGKIWEK-EKEAPTRIWLTPPTKMDAAQLMREGYYSIYSNIGARTEIPGCSLCMGNQARVRSKSTVIS 778
WP_011139059 703 GSCMTNIGHYRALGEILKG-EGAVPTTLWIAPPTKMDEKQLTQEGYYAIFGAAGARIEMPGCSLCMGNQARVRDGAVVFS 781
WP_013885864 765 GSCMTNIGHFRAAGKIWEG-EKYPQTRIWVTPPTKMDEAKLKEEGYYSIYSQIGARVEIPGCSLCMGNQARVRPETNVLS 843
WP_128467469 697 GSCMTNIGHFRAAGKIWEG-AAYPKTKIWLTPPTLMDQMQLMEEGYYSIYASVGARTEIPGCSLCMGNQGRVQPKAHVLS 775
1L5J_A       788 TSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYV-AQVDKTAVDTYRYLNFNQLSQYTEKADGV 859
WP_011365887 781 TSTRNFDDRIGDGAKVFLGSAELGAVTATLGKLPTVAEFMAAYkEKVEPKKDVVYKYLQFDEMPEYK------ 847
WP_011498480 777 TSTRNFDNRVGDGAQVYLGSAELGAVISNLGRIPTVNEYMEIYmEKIEPKQDEIYRYLQFDEMEEYL------ 843
WP_011735582 779 TSTRNFDDRMGNGARVYLGSAELGAVVALLGRLPEPDEYLRLYrERVEPQRERIYRSLRFDERSEQ------- 844
WP_012632657 777 TSTRNFDDRMGNGARVFLGSAELGAVAANLGRLPTVAEYFAVYnEKIAPKAGQVYRYLQFDELAEYKGFRVVA 849
WP_013507048 777 TSTRNFDNRLGDGAQVFLGSAEVAAVIALTGKIPTPQEYLDIYrQRVAPHAADVYNYLQFDELPQDIVSLV-- 847
WP_013451110 779 TSTRNFDDRMGDGARVYLGSAELAAIAALLGKLPTPEDYFKYMnERVEPKKTEIYKYLEFHKMGNFKLTYVD- 850
WP_011139059 782 TSTRNFNNRMGKDAQVYLGSAELAALCAMLGRLPTKEEYLALIpQKIAGKESQIYRYLNFHEIEDYRLTQGR- 853
WP_013885864 844 TSTRNFDNRIGDGAQVYLGSAELTAITGLLGKLPSVDDYMDIInKKVTPNKEEIYKYLEFDKMGKVKLTYS-- 914
WP_128467469 776 TSTRNFPNRIGDESQVYLGSAELTAVTALMGELPTPAEYFMLYkSKIEPKQAEVYRYLEFDKMGDFELSYIER 848
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