5XBW,1JYH


Conserved Protein Domain Family
Cass2

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pfam14526: Cass2 
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Integron-associated effector binding protein
This family contains Cass2 from Vibrio cholerae, an integron-associated protein that has been shown to bind cationic drug compounds with submicromolar affinity. Cass2 has been proposed to be representative of a larger family of independent effector-binding proteins associated with lateral gene transfer within Vibrio and other closely-related species.
Statistics
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PSSM-Id: 434016
Aligned: 28 rows
Threshold Bit Score: 79.3228
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5XBW_C        125 RIVERPAFSVVGMEYFGSAPGD--------------TI-GQLWERFIPRE----HEIA-GKHd-pEVSYGICAQQP---N 180 Pseudomonas ae...
WP_015844446    5 TIEHKKSFTLTAYGFSIQSNFQdmta-------lqkEK-SEFWGKLKADGr---FAKL-KDAakdDREWSVNEVYQgkpW 72  Paenibacillus ...
WP_015735692    5 TLEEKDSFIVLGIGTELKSDYTdyag-------inkEK-TEFWESVKQDGrldtLKAI-AAN---DYIFAVNEa----vN 68  unclassified P...
WP_014824796    5 TIEEKDSFVVLGFGTELKSDYTdymg-------inkEK-ADFWHAVNEDGr---LDAL-KAVa--TNDYIFIV-NEa-vN 68  Solibacillus s...
Q81AW8          7 TIEEKDSFIVLGIGTEIKSEYTdfag-------inkEK-EDFWSAVKEDGr---LDTL-KALa--TNEYIFSVSEa--vN 70  Bacillus cereu...
Q97LX8        131 KIETKKSFKIAGVSKRISTKEGnn----------fkII-PEFWDEVKKSGq---CEII-EKNagkLGVMGVCTNFDc-eY 194 Clostridium ac...
jgi:Cphy_3142 131 RIETKEAFDVFGIETVASLSGEdsfvspaelwrkshQN-GDYERLFNASGd---LPKF-ISQd-lCKIHGVENYRKt-eG 203
Q8Y8J0          7 RLEEWEGFTGIALVREGLKAEAlh-----------tEI-KTAFKEILQLAr--eLDDF-SKQ---KIFYGISVHNIe--- 65  Listeria monoc...
Q180I1          5 SIKELNAFAVIGQEVELTNYQKkn-----------iQIsTQFWRKFNS--------SL-KKSy--LSQSGNWVKYAfmeR 62  Clostridioides...
WP_004238549  133 ELTELPEMLLAGSHHYHRKHLSdw----------qtEN-RKFRREFWEKF----FKEVdIIP---ADLYAIHAPYEs-tA 193 Morganella mor...
5XBW_C        181 GEFHY-VAGFEVQEG----WPVPEGMVRFQVPAQKYAVFTHK------GTAPQ-IAESFQAIy-SHLLAe--RGLEPKAG 245 Pseudomonas ae...
WP_015844446   73 NYFAV-EAGKSVTD----------ATRIIEFPESEYIVVAGN------GDKETlFDQLTYLAf-GEVLSr-aTDYAYIGG 133 Paenibacillus ...
WP_015735692   69 NKMMY-YAGVMTEE------SLPEATRVIQFPKGEYLVVKGE------GKTADeLSNKLTGIafGQVLPs-aKDFAYVGG 134 unclassified P...
WP_014824796   69 NKMMH-YAGVLTDE------TLPEATRVIQFPKGEYVVVKGE------APTAEeLANTVTGIafGQALQe-aTDYAYVGG 134 Solibacillus s...
Q81AW8         71 NKMMY-YAGVMTEA------QIEEESRVIQFPRGEYLVVKGE------DKTAKeLSNKLTGIafGQALPe-aKDFAYVGG 136 Bacillus cereu...
Q97LX8        195 QEFDY-LIAVEGDK-----IEGLDNYVVIEVPELSFAVFESI------GPMPDaLQDVTRRIf-SEWFPa--TKYEEAEG 259 Clostridium ac...
jgi:Cphy_3142 204 NTFPY-MLCSFVSD-----SFKTDGYTIQHIPSQTYAIFPSEkfmwneGSMEv-LRNLQKRFy-SEWLPt--ANYERVSG 273
Q8Y8J0         66 DGITH-YSAIPVEQKy---SNLKEPLEWIEVPAHTYFVAEHI------QD--TdIGESYEEIa-RAIQEknyKPYITANN 132 Listeria monoc...
Q180I1         63 RNGKL-YYFCSIPKR----TILPDNFLYKEIPSYKYLVVEHI------GAMGK-IYETYRKIy-QEIIPn--TPYTPIKN 127 Clostridioides...
WP_004238549  194 DDISYaYTTAVIPSVlsadSIRRASLSPVTLPGGHYLRITIDpa--mlKNLPAdYNNIIHAAy-SGTLAe--MNLLRRRG 268 Morganella mor...
5XBW_C        246 V-------D--FEYY-------DqrfrGpl--------dpNSQVDLYIPI 271 Pseudomonas aeruginosa PAO1
WP_015844446  134 P-------N--ATYR-------KdngdG------------TFYGEFWVPV 155 Paenibacillus sp. JDR-2
WP_015735692  135 P-------N--ATVE-------MeerdG------------FVSGELWIPV 156 unclassified Paenibacillus
WP_014824796  135 P-------N--AAVV-------MdqqnG------------QVYGEMWIPV 156 Solibacillus silvestris
Q81AW8        137 P-------NttVEMG-------Qrn--------------gLVFGEMWIPV 158 Bacillus cereus ATCC 14579
Q97LX8        260 P-------E--IEVY-------LpgnpQd----------kDYRAEIWVPV 283 Clostridium acetobutylicum
jgi:Cphy_3142 274 A-------N--FEIYgg----dK----E------------YGYIELWFPV 294
Q8Y8J0        133 PvfdplpfK--LEVY-------TkqgsD------------ETNIEIRIPV 161 Listeria monocytogenes
Q180I1        128 Ii-----lH--FEKYdyrfhwnRd----------------NSVIEIWIPI 154 Clostridioides difficile 630
WP_004238549  269 P-------D--IEHY-------KllpaErhdefianglqyVEEINYYIPV 302 Morganella morganii
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