Conserved Protein Domain Family
matur_MocA_YgfJ

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TIGR03310: matur_MocA_YgfJ 
molybdenum cofactor cytidylyltransferase
Members of this protein include MocA, which transfers cytosine from CTP to molybdopterin during molybdopterin cytosine dinucleotide (MCD) cofactor biosynthesis. It is distantly related to MobA, the GTP:molybdopterin guanylyltransferase. The MocA family is particularly closely related in phylogenetic distribution to other markers of selenium-dependent molybdenum hydroxylases (SDMH), suggesting most SDMH must use MCD rather than molybdopterin guanine dinucleotide.
Statistics
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PSSM-Id: 274516
Aligned: 11 rows
Threshold Bit Score: 228.378
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011459387   3 SAIVLAAGKSSRMGQMKLLLPIAGLSMIRAVVENVLRSQADEVIIVLGNEAdrvrndIELLGAgdesvKSKLKIVENLQF 82  Desulfitobacter...
WP_012047953   3 SAVIMASGYSTRMRKNKLMLPFKGKPIIEHVIDAIKECNFNEIILVGKEKK------VLDIAR-----RKNILTVLNTKA 71  Clostridium bot...
WP_011218689   7 DCVMPAAGLSSRMGDWKLMLPYRQHTILDESIENAL-LFCSRVIVVAGHRHee---lVKHYCR-----HDNVLVVINSHY 77  Photobacterium ...
WP_004513065   8 AGIVLAAGKSTRMGRPKQLLPFRGRTVLECVVDNALASRLHRVVVVLGHEAea---vMPLLG------HRCVTTVVNPLY 78  Geobacter metal...
WP_009890188   3 NAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQVVVVSQYEE------VLLLCN-----KYGFEYIDNKNA 71  [Clostridium] d...
WP_011190305  16 DAIIPAAGFSRRMGTNKLLLPLGGKTLLEVFLDAFPYHLFRSVFLIYADDQ------VAGCAG-----SYPLHLVRNSHP 84  Desulfotalea ps...
WP_001272860   5 DCIITAAGLSSRMGQWKMMLPWQQGTILDTSIKNALQ-FCSRIILVTGYRGne---lHERYAN-----QSNITIIHNPDY 75  Escherichia
WP_011706026  29 DCLITAAGLSSRMGAWKLMLPYRQSTILDESLKNAL-VLCDRVILVVGHRAde---lISRYAN-----HPRIRLVHNHDY 99  Aeromonas hydro...
WP_002362242   5 SVIILASGNSQRMGQNKLFLKYQGKTFLEHTLTLVNQLDVLERILVVSPENqp---aFPL--------PKNIQLILNHQW 73  Enterococcus fa...
WP_011393499 261 GVIVLAAGAGERMGGGKLLLPLKGQPLVRRVVLTALEAAGDKVVVVLGHESdk---tAAALAG------LKVDLAINPAY 331 Moorella thermo...
WP_011343624   2 GVLILAGGSSRRMGKDKLSLPLFGKTILEQTV-AIYRRVFAEVEVITKDRIge---sFAL-------------------- 57  Carboxydothermu...
WP_011459387  83 AEGQSTSLKVGL-S-MvNEQSAGALILMGDQPFVGTEIIDTIIECFLETVPLMVVPQYPEGRAS-PVLFARDLFPELMAV 159 Desulfitobacter...
WP_012047953  72 YQGQSQSIKLGI-L-N-ISSSKGYMFFTGDQPLLNSYTINLLLNTFTKNNDYIVIPKYKNKVGS-PTIFPEKFKNELLNL 147 Clostridium bot...
WP_011218689  78 QQGMFSSIQVGV-E---HVESEHFFICHGDMPCVPADIYQQV---WALKDQCTVFPGTLNKPGH-PVLLPNNMIDIIKNA 149 Photobacterium ...
WP_004513065  79 GEGQSSSLKAGLgA-M-TEETDAALFLLGDQPLVTADTINLLIAAFADFPSPIVIPTFEGHRGN-PVLFSRETFPRIEAL 155 Geobacter metal...
WP_009890188  72 NIGQSESIKLGV-L-N-SSKCDGYMFFVGDQPFIDNLYIDKIINTFKLDRDFIVIPRYKDMCGN-PVIFPYSKKEELLAL 147 [Clostridium] d...
WP_011190305  85 ERGQSYSVRLGL-E-L-SRAQDGFLFAVADQPCLRPASIERMVALFSRDKSRIVRPEVAGKPRN-PVIFPASLGPQLLAL 160 Desulfotalea ps...
WP_001272860  76 AQGLLTSVKAAV-P---AVQTEHCFLTHGDMPTLTIDIFRKI---WSLRNDGAILPLHNGIPGH-PILVSKPCLMQAIQR 147 Escherichia
WP_011706026 100 AQGLGSSIRAGL-A---ACSSDHLFVSHGDLPCIPPEVYRTL---WQARGDETLFPSYQGEAGH-PVLLPRALVRALAAA 171 Aeromonas hydro...
WP_002362242  74 QEGQSSSIRLGT-E---QARGAGYLYLPSDQPLLTPKMLQLVLD--KCQRNKIVVPLQKDGCPSsPVLFGNQFRQELLTL 147 Enterococcus fa...
WP_011393499 332 RLGLSTSLQAGL-AaL-PPRTPAALFVLADQPGVTPSVLRQLLEAYRPGGRRIIVPVYRGRRGN-PVLIDRGLWPQILNL 408 Moorella thermo...
WP_011343624  58 -EGMGGTLRGAA-R-LlPDHWQGVVIALGDMPFVGINSLQALSRAIAMKPEEVWCLSYRGRRGH-PVYLPRKYFSYLKRL 133 Carboxydothermu...
WP_011459387 160 TGDKGGRSIVmkcleTERRHHVSIVEVKSGLAGRDIDTWEEFLNV 204 Desulfitobacterium hafniense
WP_012047953 148 QGDVGGKIVI-----NNHINEILFVNLKNGYSLFDIDTPKDYEYI 187 Clostridium botulinum
WP_011218689 150 PITSKMKPLI-------MAHTVKYLGLKCDEIYLDIDTPDAYQSL 187 Photobacterium profundum
WP_004513065 156 SGDRGARGLF-----REYGDDIRSIDVRTPAILFDLDTEEDYLRL 195 Geobacter metallireducens
WP_009890188 148 KEDEKGKTIL------KNSSKIKYVEVPK-EMLFDIDTKMDYERI 185 [Clostridium] difficile
WP_011190305 161 EGDEGGRQVI-----RAHPHLLCSLEFSDSAEFVDIDTPERYQQL 200 Desulfotalea psychrophila
WP_001272860 148 PNVTNMRQAL-------LMGEHYSVEIENAEIILDIDTPDDFITA 185 Escherichia
WP_011706026 172 PAQGSVRRWL-------LAHPHRFIEVQSAAILQDVDTPERYQAL 209 Aeromonas hydrophila
WP_002362242 148 TGEKGGRMIY-----ERFPEAVQMLRIATPGRLKDIDTPEEYQKL 187 Enterococcus faecalis
WP_011393499 409 KGDIGAREII-----REYPEEVLPVEVSCPGIFQDIDTPADYRAW 448 Moorella thermoacetica
WP_011343624 134 TGDTGLRDLL-----PEL--SPKYIDTEDYGVLFDIDKSDDYLPF 171 Carboxydothermus hydrogenoformans
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