5Y0P


Conserved Protein Domain Family
TmcAL

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COG1323: TmcAL 
tRNA-Met C34-N4-acetylcytidine synthase TmcAL [Translation, ribosomal structure and biogenesis]
tRNA-Met C34-N4-acetylcytidine synthase TmcAL is part of the Pathway/BioSystem: tRNA modification
Statistics
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PSSM-Id: 440934
Aligned: 127 rows
Threshold Bit Score: 342.933
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5Y0P_A        20 MK--AVGLVVEYNPFHNGHLYHAQTAKLQTGCDTAVAVMSGHFLQRGEPAVVSKWARTKMALQSGVDLVIELPYLYAVQK 97 
NP_603629      1 MFenVVGLIVEYNPFHNGHLHHIQEIDRLFEDNIKIAVMSGDYVQRGEPSLINKLEKTKIALSQGIDIVIELPTFYSTQS 80 
WP_011917315   1 MK--AAGIIVEYNPFHNGHLYHLQKTKEITGADVVVAVMSGNFIQRGEPAIVNKWARTKMALLNGVDVVFELPFAYACNS 78 
WP_013387875   1 MK--ATGVVVEYNPFHNGHRYHLEKAREKGIGDVVIAAMSGDFLQRGEPGIINRWKRAEMALRSGVDIVAELPAYYSNQS 78 
WP_013669639   1 MS--VCGMIVEWNPFHNGHAYLIQQLKGRQPDTVIIAIMSGNYVQRGQAALLSKWQRAEVALKNGCDLVIELPFWYAVQP 78 
WP_015075984   1 MK--SCGVIVEYNPFHNGHRYHIQQARLKSGADVVIAVMSGNFLQRGEPALLDKWARAEMALAAGIDIVVELPVYSSVQA 78 
WP_083540618   2 MK--ACGIIAEYNPFHNGHLYQLEEAKKRTGAEVIIVVMSGNFLQRGEPAIVDKWKRAKMALAGGADLILELPVSYSVQP 79 
WP_077140463   2 MN--ALGIISEYNPFHNGHLYQIQCARQDHPDSVIIALMSGDFTQRGELACLSKFDRTRTVLPH-VDLVIELPHQFAIQS 78 
WP_077795706   1 MK--SCGIIAEYNPFHSGHAYHLQEARRQSGADILTVAMSGNFTQRGEPAIFDKWQRARAALENGADLVVENPVLGSAQA 78 
WP_118990073   5 VK--ALGIIAEYNPFHWGHAYQLAKARQLAGDCPIIVLMSGNVVQRGEFAVLDKWTRARLALSYGADVVIEAPITATLQG 82 
5Y0P_A        98 ADIFARGSVSILNELECEALFFGSENGDIKPFLETAQLID---EHKHILNDRIKEELKKGASYPAAAAIAFSSILHT--- 171
NP_603629     81 AEIFAKGSVNLLNKLSCSHIVFGSESNDLDKLKRIATISL-----TKEFELSLREFLAEGFSYPTAFSKVLFDE------ 149
WP_011917315  79 AEVFAYGAISILNSLGVNWVVFGSEAGDISLLKKIAMHLA---FEEDEFKKYLKIYLKEGHSFPKARELALKRVSKE--- 152
WP_013387875  79 AEIFARGAVGVLGALGVSDIVFGSESGEIERLKNIASL-----EENDEFQIYLKEELGRGSSYPTSFAAAIEKITGE--- 150
WP_013669639  79 ADLFAEGAVGCLQALGCQQLAFGSELEDFAPYQKLAQWVS---DHEETVALKQQNEAFHANNYGKSSISLLADLVAEvpe 155
WP_015075984  79 ADYFAEGGIALLHALQCDSFCFGSENGKEKDFQQVAKWLI---DEKEAFDQAFQMVKNSGSSYAAQVEALLKEVYPT--- 152
WP_083540618  80 ADLFAKGAIEILAGLGCASLSFGAESGNGETFKKAAKLLI---EYSEDIDDQFKKQNEKGKPYAVRMEQAIAAVIPS--- 153
WP_077140463  79 AQYFAQGAIEALRHLNVSTLSFGSESGSIDQLTKIAKKLHiinEEYKNDKHEVISYMRRGNTYAQSMNQLLDN------- 151
WP_077795706  79 SDLFAKSGVRILQALACDWIAFGAENGSSQEFSELAQALV---EQEATINQTFHQVKNDGRSYAVQMNEAIQKVMKP--- 152
WP_118990073  83 ADYFASKHIQLLAKLGIDAFLFGTEQAQVSDLEALLDFQE---RHADALDDGIQKYLQKGHSYAASVELAMQAIYDA--- 156
5Y0P_A       172 ---ESALDLSKPNNILGYQYVTSILTGGYPMKPYTTARISSDYHDADLpegE--N-HIASATSIRKAMIGQ------NL- 238
NP_603629    150 --------KLGSNDILALEYLRAIKTINSKIEAYCIKREKTGYYDDEK------D-NFSSATYIRKILLDSnekkenKL- 213
WP_011917315 153 ------DIEFLPNNILGVEYIKWILRTNSKIEPLTIKRVGSLYNDPNLg--S--G-SFCSATAIRQNINNL--------- 212
WP_013387875 151 ------KGYMTPNDILGTEYVRSIAKLRLNINPIAIKREGTGYHSHDI---K--D-DIASATAIRKMLEk-------EM- 210
WP_013669639 156 lrhLKIDFTDNSNVLLAYSYAKANAKYQAPMTLTAIKRQGSQHRDQDM---SpgA-NYASSTSIRKALLEDqv-----dp 226
WP_015075984 153 ----LSLNLSEPNNALGLSYAKANLAYPKPMEMYTIKREKAGYHETTI---Q--DlEFASATAIRKSLIKKe-------- 215
WP_083540618 154 ----FPINLSKPNNQLGLAYAKENYYHGDRFHFEVIGRKQAEYHDVNL---SenT-TIASATAIRKQLLNPl-----NVq 220
WP_077140463 152 ------QFNDTPNDILATQYIYHNMMLDQPMTLHTVQRKTSHHHNKKL---Tk-D-PFTSGTSIRNNWSTQidqnpnNT- 219
WP_077795706 153 ----SRIALEQPNNQLALAYLKENVSYPHPMQALAILRRGADHHAQQAv--S--T-HFASGTSLRLLLLAK------EY- 216
WP_118990073 157 ---PANFQRDAPNHLLSLQYLRANRQLAKPLTPLSLQRVQAFQGH-----------KVLSGSQIRQALSAG--------- 213
5Y0P_A       239 EACLRFLPAA-SARELAAYRKsfglwHTPESYFSYLKYSLSTvtARELQQVYEVEEGLEHRI---IRSIRKSSSYQEFME 314
NP_603629    214 NKIKNLVPEF-SYKILEENFGv---fSCLSDFYDLIKYNIIk-nCSELKNIQDLEIGLENRL---YKYSLENLKFEDFFN 285
WP_011917315 213 ELIRDKMPPF-SYQVLMEEIEsgrgpVSLNDFFEFFLYRAIv-yKDFLKEQFDVKEGLENRF---YKHIFSSSSLEDLLS 287
WP_013387875 211 EKIKNLVPEP-VYEILSNEFRkkr-cawLHEFYPILRHEIIl-hKDSLEKIQDVEAGFENRL---YEAALKNRDFEKFYG 284
WP_013669639 227 HQLDQLMPKA-MVEKLELVNYd----SSWSALYPLLRYKILSesRHKLADYYQVYEGIEKNF---IEAARKETCYADFLN 298
WP_015075984 216 STVESVMPAS-SLELVNQEKF-----VSWENYWLLLRYQIMVstVDDLQQIYQMNEGIEFRL---KEKVKEAETFTEFIG 286
WP_083540618 221 NSSQAFMPAT-SLELLNQSQL-----INWNNYWRLLKYQILSssLKELQQIYQMEEGLEYRL---KKAVQSADSFERFIQ 291
WP_077140463 220 VNLSQYVPPS-TYQFIQKQKP-----NSNDLFLPYILFTLERinYEDLMRIHLMKEDFAHRLikyKQQMRHIESFDALCL 293
WP_077795706 217 DNLEQWVPNAkTLKVLEP--------LDWEKYWPFLRYQIILqsHADLQSIYQMEEGIEYRL---KDKIKQADSFASFIG 285
WP_118990073 214 KLLEDSVPPE-TYQVLLDAAL-----PQMEAYYPMLRYRVLTlsKTDLANMYGIREGIEARF---MAACQEHTSFEAFTQ 284
5Y0P_A       315 LLKTKRYTWTRLQRMNTHILTRTKKQDMQKlLDn--dKAPYIRLLGMTKKGQAYLSEKKK--ALSV---PLVSKLSSFSH 387
NP_603629    286 EVLTKRITISRLQRILLHSLFNLTENITEK-VKn---EVPFVKILGFSTKGQKYLNYLKK--SKNYnerKILTSNRNLKE 359
WP_011917315 288 KVKTKRYTLTRLQRILIHCLVDSKVNQKTL-LS----TKPYIRVLGFNSRGKRYLNSIKE--KVK-----YITKLDSYIM 355
WP_013387875 285 DIMTKRYTNARIQRILTHILLGLTVKITEK-AKm---GVPYVRILGFNQEGGRYLKSIRG--KTGI---EVFTTLKNVSK 355
WP_013669639 299 QVTNKKWSKYRIQRALLMIFLGVSDQEMQD-HLkk-rQP--LYLLGANSRGRKYLKGLEItdPSSY---AMINRVGRDES 371
WP_015075984 287 LVKNKRYTWTRIQRLCIYILLQLKKTDVEA-SVe---GLKAIRVLGFTEQGRSYLKAKKT--KIEL---PIVTNLNAANK 357
WP_083540618 292 TVKNKRMTRTRLQRLCVYVLLQIKHSDLAA-LN----QMPTSRILGFSPLGQQYLSEVKK--SSSV---NLLTKINKLTK 361
WP_077140463 294 LLKSKNYTYTFIQRMLIHIMLNIQTID----------EIKGLRVLGMNQKGRKYLKQLNSd----I---EIITNVNKQNk 356
WP_077795706 286 LVKNKRWTWVRLQRLCLYVLLGIKKEEVLS-FYk---NEPVLRILGFNKKGQAYLNQLKH--QRDL---TIVTNLNKKTA 356
WP_118990073 285 YMISKRWTRASIQRLSMHVLLNHQLDTWQQ-ADidtkAKPALRILGMSQRGQAWLKHVDT--EQV----DLFSNLKQKH- 356
5Y0P_A       388 PAl-------DLDVKASRIYSLPIEEPLRTefdlQEYgh--apIRY 424
NP_603629    360 ILneeeaklfNFNELCSQIYRIk-----------SSYinigypIIK 394
WP_011917315 356 Knpey-nsllELEIRASQIHALKYKEYHKYl--qLEFkq--hpIYI 396
WP_013387875 356 KLsgrekallDFNERCSMIYTVI-----------KEYeerktpIII 390
WP_013669639 372 Ka-------wPLWIRVDEIYQQVVMKSKES----QLFah--ppIML 404
WP_015075984 358 Nf-------fDLDIRAGFIYQLGNPHILP-----QDYrr--kpIYQ 389
WP_083540618 362 Dn-------wSLDIKAGEVYQLALDNVKLK----QDFnr--kpLNI 394
WP_077140463 357 h-------liRQNIESTNMYNFITKHKE------NDFnr---pVIL 386
WP_077795706 357 Sl-------lPVEIRADRIYILPSGKE-------QNFsr--ipIMV 386
WP_118990073 357 -Fpr-----yELNYQADQVMQLGDWQSVPE----QNRsr--fpMII 390
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