1RTY,1WOZ,1WVT


Conserved Protein Domain Family
PduO_Nterm

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TIGR00636: PduO_Nterm 
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ATP:cob(I)alamin adenosyltransferase
This model represents as ATP:cob(I)alamin adenosyltransferase family corresponding to the N-terminal half of Salmonella PduO, a 1,2-propanediol utilization protein that probably is bifunctional. PduO represents one of at least three families of ATP:corrinoid adenosyltransferase: others are CobA (which partially complements PduO) and EutT. It was not clear originally whether ATP:cob(I)alamin adenosyltransferase activity resides in the N-terminal region of PduO, modeled here, but this has now become clear from the characterization of MeaD from Methylobacterium extorquens. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Statistics
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PSSM-Id: 213544
Aligned: 13 rows
Threshold Bit Score: 232.225
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1RTY_A         4 YTKTGDKGQTGLVGG-RTDKDSLRVESYGTIDELNSFIGLALAEL--SgqpgFEDLTAELLTIQHELFDCGGDLAI--VT 78  Bacillus subtilis
WP_002382343   4 YTKTGDKGMTKLVGSsTVAKDSDRVESYGTIDELNSWVGYIISQLpqE----NQEIKEELEALQHLLFDAGTDLST--PI 77  Enterococcus fa...
WP_010979504   2 FTKSGDDGNTNVINk-RVGKDSPLVNFLGDLDELNSFIGFAISKI--P----WEDMKKDLERVQVELFEIGEDLST--QS 72  Sulfolobus toko...
CAA11738       4 YTKTGDKGQTGLVGG-RTDKDSLRVESYGTIDELNSFIGLALAEL--SgqpgFEDLTAELLTIQHELFDCGGDLAI--VT 78  Bacillus subtil...
BAB59239      15 FTRRGDTGETDLASRvRVGKDSPIVEVQGVIDELNAFIGQALVLT--K----WEDIRKDLFKIQNDLFVLGEDVST--GG 86  Thermoplasma vo...
WP_011002573   9 ATRTGDDGTTGLGDGsRTGKDGLRIAAIGEVDELNSHLGVLLTEP--L----PDDVHAALTAIQHDLFDLGGELCI--PG 80  Ralstonia solan...
WP_010980260   3 YTGTGDKGKTKVPSVgEVWKDSEIVKALGDLDELNSVLGVVSSL--------YPELSEVIQKLQNDIFSISSEIAG---F 71  Sulfolobus toko...
WP_000708720   4 YTKKGDFGQTSLATGvKVPKSDRRVELYGTADELNSTIGVVKSFLr-K----ESILHSSLEIIQNLLFELGAELAGfrPK 78  Leptospira inte...
WP_010868490   4 TTKVGDKGSTKLFGGdEVWKDSPIIEANGTLDELTSFLGEARHYL-------NDEMREIIDRIQMDIYKIMGELGS--KG 74  Pyrococcus abyssi
WP_010888275   4 YTRTGDQGQTGLYGAdRVSKAHPRVEAYGTVDELNSALGLARAHS--T----DAALDTDLEYLQNALFDVGADLAT--RS 75  Deinococcus rad...
WP_010918615   8 YTRTGDGGTTRLATGaPVSKASLRVDSYGGVDETNAAIGQARQHT--Aa---DPVLDAILERIQNDLFDLGADLAT--PE 80  Caulobacter vib...
1WOZ_A         2 FTKSGDDGNTNVINk-RVGKDSPLVNFLGDLDELNSFIGFAISKI--P----WEDXKKDLERVQVELFEIGEDLST--QS 72  Sulfolobus toko...
1WVT_A         3 YTGTGDKGKTKVPSVgEVWKDSEIVKALGDLDELNSVLGVVSSL--------YPELSEVIQKLQNDIFSISSEIAG---F 71  Sulfolobus toko...
1RTY_A        79 ERKd----yK-------LTEESVSFLETRIDAYTAEAPELKKFILPGGSKCASLLHIARTITRRAERRVVAL--XKS-EE 144 Bacillus subtilis
WP_002382343  78 EAQrp---fK-------LQKASVHWLEQRIDFYTAQSPDIDRFILPGGTPAASMVHVARTIARRAERIIVRL--NWT-AK 144 Enterococcus fa...
WP_010979504  73 SKK------K-------IDEKYVKWLEERTVEYRKESGPVKLFVIPGGSEEASVLHVTRSVARRVERNAVKY--TKElPE 137 Sulfolobus toko...
CAA11738      79 ERKd----yK-------LTEESVSFLETRIDAYTAEAPELKKFILPGGSKCASLLHIARTITRRAERRVVAL--MKS-EE 144 Bacillus subtil...
BAB59239      87 KGR------V-------VTREMIDYLEDRVNVLRKEIGKIELFVIPGGTLEATSVHIARTVSRRLERRIVFA--NHY-TD 150 Thermoplasma vo...
WP_011002573  81 HT-------M-------VTPAHVLRLDQWLADYNADLPRLAEFILPGGSRAAAQAHVCRTVCRRAERAIVAL--GRA-ET 143 Ralstonia solan...
WP_010980260  72 DMN--------------FSDEKVKGIEELITNYSKELEPLRNFVLPGGHIASSFLHLARAVCRRAERSVVTL--LKE-SK 134 Sulfolobus toko...
WP_000708720  79 QES------C-------ILEEDITFLENQIDQMQEKLEPLKKFILPGGTKAAAFLHISRTVSRRLEREMVKF--KEEgLE 143 Leptospira inte...
WP_010868490  75 DIK------G-------ITDEDLKWIEGIIEKY-EGEVELRSFVLPGGTIESAKLDVCRTIARRAERRVATI--VRE-YG 137 Pyrococcus abyssi
WP_010888275  76 GTPyeknlvR-------IDAEDVAFLEAMIDRYQEAAPPFTGFVHPGGTPAAAALQLARAVARRAERDVIRL--LDV-EE 145 Deinococcus rad...
WP_010918615  81 QHG------KpeweplrVVESQVERLEREIDQLNGEMSALTSFVLPGGSPAAAALHVARTVCRRAERGVVALseMDG-EI 153 Caulobacter vib...
1WOZ_A        73 SKK------K-------IDEKYVKWLEERTVEYRKESGPVKLFVIPGGSEEASVLHVTRSVARRVERNAVKY--TKElPE 137 Sulfolobus toko...
1WVT_A        72 DXN--------------FSDEKVKGIEELITNYSKELEPLRNFVLPGGHIASSFLHLARAVCRRAERSVVTL--LKE-SK 134 Sulfolobus toko...
1RTY_A       145 IHETVLRYLNRLSDYFFAGARVVNARsGIGDVEYE 179 Bacillus subtilis
WP_002382343 145 INEEVLIFTNRLSDYFYALARCLNVQaQRPDVFYE 179 Enterococcus faecalis
WP_010979504 138 INRMIIVYLNRLSSLLFAMALVANKRrNVSEKIYD 172 Sulfolobus tokodaii
CAA11738     145 IHETVLRYLNRLSDYFFAGARVVNARsGIGDVEYE 179 Bacillus subtilis subsp. subtilis str. 168
BAB59239     151 INKNVLIYANRLSSLLFMIAMVSNKRqNVEEKIWP 185 Thermoplasma volcanium GSS1
WP_011002573 144 LGEAPRQYVNRLSDLLFVLARVLNRAgGGQDVLWE 178 Ralstonia solanacearum
WP_010980260 135 AKEVHAKYLNRLSSLLFVLALVVNKRtNNPNVIWR 169 Sulfolobus tokodaii
WP_000708720 144 ILSSPMIFINRLSDYFFVAARFANLEeNIQEPLWT 178 Leptospira interrogans
WP_010868490 138 FARKSLVYLNRLSDLLFLMARKIEIEkGKLREVRA 172 Pyrococcus abyssi
WP_010888275 146 ANAQVQVYLNRVSDLLFIMARAVNARsGLSEEAWT 180 Deinococcus radiodurans
WP_010918615 154 VGTPAIKYLNRLSDLLFVAARWANDK-GQADVLWK 187 Caulobacter vibrioides
1WOZ_A       138 INRXIIVYLNRLSSLLFAXALVANKRrNVSEKIYD 172 Sulfolobus tokodaii str. 7
1WVT_A       135 AKEVHAKYLNRLSSLLFVLALVVNKRtNNPNVIWR 169 Sulfolobus tokodaii str. 7
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