Conserved Protein Domain Family
LdtF_DpaA_YafK

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NF040599: LdtF_DpaA_YafK 
peptidoglycan meso-diaminopimelic acid protein amidase
DpaA (previously YafK and LdtF) murein L,D-transpeptidases, but actually functions as an amidase. In E. coli, the most abundant protein is the lipoprotein Lpp, anchored to the inner face of the outer membrane, but cross-linked to the peptidoglycan cell wall by the transpeptidases LdtA, LdtB, and LdtC. DpaA (peptidoglycan meso-diaminopimelic acid protein amidase A) is an amidase that hydrolyzes those linkages.
Statistics
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PSSM-Id: 468573
Aligned: 20 rows
Threshold Bit Score: 452.539
Created: 24-Apr-2023
Updated: 4-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_016193134   1 MGKIALLFAMFF-LPTVVFASVPaTQVAPLAPVRkefKKQ----LLGAPVYLQIFKEERVLELYGKIGTEYRLLDSYRIC 75  Erwinia trachei...
WP_017371324   1 MRKIALFFAMLL-LPCVSFAGLL-GSNPSPla----dKKQ----FMGSPVYIQIFKQERTLELWVKSGEKYQLMSSYNIC 70  Enterobacteriac...
WP_004720248   1 MGKITLLLALIIcLPAVSV-TSSaSEPVTMAKEL---KQQ----LLGSSVYIQIFKEERTLELYARLQGEYRLLQSYRIC 72  Yersinia ruckeri
WP_012304521   1 MGKIALLFAMIIcLPAASF-TSSaSEPVAVSKEL---KQQ----LLGSSVYIQIFKEERVLELYAKLQGEYRLVQSYPIC 72  Yersinia pseudo...
WP_015696179   1 MIRIALFLAMLLsLPLFTANYAAaSDAVPVNAAL---KKQ----LLGAPVYIQIFKQERKLELYAQLDGEFRLIGSYGIC 73  Rahnella aquatilis
WP_017491490   1 MVRIALLLAMLFsLPFFAVSTAVaSEQVPVESGV---KQQ----LLGSPVYIQIFKQERTLELYAKVEDKFQLVGAYRIC 73  Rouxiella badensis
WP_004954951   1 MSRIALLFAMLFsMPMIT--ACSaSEQVPETPVV---KQQ----LLGSPVYIQIFKEERKLELYAKMGNEFRLVNTFPIC 71  Serratia odorifera
WP_009111673   1 MQKIALSFAMLFfLPSFAVT-SAaSEPAP-LTPI---KKElkqqLLGSPIYIQIFKEERLLELYAKVGNEYRLLEHYPIC 75  Brenneria
WP_016941708   1 MHKVAFSLAMLFlLPSVAISNSYaNQVAPAATET---KQQ----VAGSPVYIQIFKEERVLELYAMIGGEYKLVQSYPIC 73  Dickeya
WP_004847632   1 MGKIIALLAVFFvLPLTSC-SSSaSEQAQNTPLA---KQQ----LLGSPVYIQIFKEERKLELFAKVQDKYQLVQSFNIC 72  Hafnia alvei
WP_016193134  76 NFSGGLGPKRHEGDFKSPEGFYSVGLSQLKPNSRFYRAINVGFPNEYDRQQGYEGKYLMIHGSCVSIGCYAMTDSNIDDI 155 Erwinia trachei...
WP_017371324  71 NYSGGLGPKRRTGDFKSPEGFYSVDRSQLKPDSQYYKAINIGFPNEFDRQNGYDGKYLMIHGACVSVGCYAMTDSGIDEI 150 Enterobacteriac...
WP_004720248  73 NFSGGLGPKRREGDFKSPEGFYSIDMQHLKPDSKFYRAINIGFPNDFDKSQGYSGKYLMIHGDCQSIGCYAMTDAYMDEI 152 Yersinia ruckeri
WP_012304521  73 EFSGGLGPKRREGDFKSPEGFYSINTRHLKPDSQFYRAINIGFPNDYDKSQGYSGKYLMIHGACKSIGCYAMTDAYMDEI 152 Yersinia pseudo...
WP_015696179  74 DFSGGLGNKRREGDFKSPEGFYNVDIHHLKPDSRFYRAINIGFPNAYDISQGYSGKYLMIHGNCKSIGCYAMTDGYMDEI 153 Rahnella aquatilis
WP_017491490  74 DFSGGLGNKRREGDFKSPEGFYNIDIHHLKPDSRFYRAINIGFPNDYDRAQGYSGKYLMIHGNCLSIGCYAMTDAYMNVI 153 Rouxiella badensis
WP_004954951  72 NYSGGLGPKRREGDFKSPEGFYSVDARHLKPDSKYYRAINIGFPNDYDRSQGYSGAYLMIHGECKSIGCYAMTNDYMDEI 151 Serratia odorifera
WP_009111673  76 KYSGGLGPKRREGDLKSPEGFYQVDLRQLKPDSRYYRAINIGFPNEYDQSQGYSGRYLMIHGECVSVGCYAMTNNYMEEI 155 Brenneria
WP_016941708  74 KYSGGLGPKMTEGDFKSPEGFYQVDLKQLKPDSHYYRAINVGFPNEYDRAHGYSGRYLMIHGECVSIGCYAMTNKYIEEI 153 Dickeya
WP_004847632  73 KFSGGLGPKRTEGDFKSPEGFYQIDARHLKPNSRFYQAINIGYPNAYDQAHGYSGKYLMIHGDCVSIGCYAMTNEGISQI 152 Hafnia alvei
WP_016193134 156 YHYVEAALRNGQPQVEVSIYPFRMTDSNLQRHRNSVYYSFWQQLQPGYAEFVQNHQPPMMSVMAGRYVLKS--AlinGKV 233 Erwinia trachei...
WP_017371324 151 FQFVTAALVFGQPRVEVSIYPFRMTDANMALHKNSYYANFWKQLKPGYDYFVQNKQPPHVNVQNGQYVVNTrpFmggNNS 230 Enterobacteriac...
WP_004720248 153 FNYVKMAFINGQSKVDISIYPFRMTEQNMQRHRNSTYINFWRQLQPGYTYFAKNRMPPPVGVINGQYVINRp------LI 226 Yersinia ruckeri
WP_012304521 153 FNYVRTAFIFGQEKVDISIYPFRMTKQNMQRHRNSSYSNFWRQLQPGYTYFAKNRMPPPVSVSNGQYVLSPp------PL 226 Yersinia pseudo...
WP_015696179 154 FTYVQAAFQFGQRNLKISIYPFRMTDANMKAHKNSSYYSFWSQLQPGYAYFEKHHQPPNVVVNEGKYEVLQp------LS 227 Rahnella aquatilis
WP_017491490 154 YNYVQAAFDNGQRNVEISIYPFKMTDSNMQLHRGSYYINFWRQLQPGYAYFQKYHQPPSVSVINGNYVVNQs------QA 227 Rouxiella badensis
WP_004954951 152 YRYVEAAFAYGQSRVNISIYPFRMTEQNLQRHRSSTYASFWRQLKPGYDYFVKNHQPPMMGVANGQYVLGKp-----lMA 226 Serratia odorifera
WP_009111673 156 YRFAEHALLNGQTKINLAIYPFRMTEHNMQRHRNSSYYSFWRQLQPAYSYFNQHYQPPAITVFNGQYVVSp------pLM 229 Brenneria
WP_016941708 154 YTYVEKALRNGQQKVELAIYPFRMTEQNMKRHSRSNYYKFWSQLQPGYAYFNRMHQPPAVSVLNGQYVVNq------sAP 227 Dickeya
WP_004847632 153 YTYVQSAFRNGQTLVDINIYPFRMTEQNMQRHRNSDYLPFWKQLQPGYAYFNEHHQPPMVNVINGQYVVNRp-----sAL 227 Hafnia alvei
WP_016193134 234 ASGNGSALALSETK 247 Erwinia tracheiphila
WP_017371324 231 QPQLASNLLFTEAK 244 Enterobacteriaceae bacterium LSJC7
WP_004720248 227 SSTPASEYALSQAK 240 Yersinia ruckeri
WP_012304521 227 TSTPTSQLALIKTD 240 Yersinia pseudotuberculosis
WP_015696179 228 NTPLPSQLAFAPMK 241 Rahnella aquatilis
WP_017491490 228 LTPQPSQLAFATVK 241 Rouxiella badensis
WP_004954951 227 SGQATTLFASTTEP 240 Serratia odorifera
WP_009111673 230 TSQPISNYAFTETK 243 Brenneria
WP_016941708 228 VGQPESHYALAKTK 241 Dickeya
WP_004847632 228 DGQSPSQLAFTQTK 241 Hafnia alvei
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