1KMI


Conserved Protein Domain Family
CheZ

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pfam04344: CheZ 
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Chemotaxis phosphatase, CheZ
This family represents the bacterial chemotaxis phosphatase, CheZ. This protein forms a dimer characterized by a long four-helix bundle, composed of two helices from each monomer. CheZ dephosphorylates CheY in a reaction that is essential to maintain a continuous chemotactic response to environmental changes. It is thought that CheZ's conserved residue Gln 147 orientates a water molecule for nucleophilic attack at the CheY active site.
Statistics
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PSSM-Id: 427881
Aligned: 89 rows
Threshold Bit Score: 190.427
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KMI_Z             16 DIIARIGSLTRMLRDSLRELG--LD-QAIAEAAEAIPDARDRLYYVVQMTAQAAERALNSV-------EASQPHQDQMEK 85 
ACL06959          307 gLFGEIGQMARALHESLREFSntLDpEMKGLVEEKLPDSSLRLEHIIELTENAASTTMDLTeviqernEKSMALMDKLKS 386
jgi:Hneap_0719     42 PVFEQVGQMTREVHEALMAFA--LDeRLDRMAEAEMPDARDRLRYVISLTEQAATRTLALV-------EEAFPLTERLVE 112
WP_022775001        9 EAYTRLGAIVREMHEALTLLG--SN--QLNSIVQEIPNARDRLTYVGKMTEDAANKVLGLV-------EKAKPDCDHLAT 77  Candidatus...
jgi:Mpe_A2875      20 EVFQQLGAITRQLHDTLAQLG--VT-PKLQQAAEGLPDARSRLNYIAEKTAAAANKVLNSV-------DQAKMEHTRIAA 89 
UCNUF:Cenrod_1300  22 DVHLRLGSLTRQLHDSLNGLG--LT-DKVRTWAGELPDAKSRLSYIARLTGEAAEKVLNSV-------DQAKVHHDHIAE 91 
Q21S48             17 DIHQSIGVLTRQLHDALNGLG--LT-DKVKGWAGEIPDAKSRLSYIARLTGEAAEKVLNRV-------DMAKAQHDHIAS 86  Rhodoferax...
WP_003077948        9 NVHYKIGVLTRQLHNSLNELG--YA-DRLRGSAGELPDAQSRLSYIARLTGEAANKVLGQV-------EVTQNRQDALAE 78  Comamonas ...
jgi:Daci_0601       9 SVHYKVGVLTRQLHDSLNELG--YA-DRLRGSMGELPDAQSRLSYIARLTGEAAEKVLNRV-------ELAKVQQDRLAE 78 
WP_011806905       15 DVHHKIGQLTRQLHSALNELG--YA-DQLRGTMGELPDAQSRLSYIARLTGEAAEKVLGRV-------EQAKSLHDHVAS 84  Acidovorax...
1KMI_Z             86 SAKALTQRWDDWFADP-ID---LAD---------------ARELVT-DTRQFLADVPAHTSFTNAQLLKIMMAQDFQDLT 145
ACL06959          387 SSSDVEVLMASLDKLMdLAtenKDQpsaenipimhgllrmAREKVQ-ACGAATDSIMESTTATNKDLVDIFTAQDYQDLT 465
jgi:Hneap_0719    113 RSERLHQQLAQVAEKE-AD---NRR---------------LVEVIH-TITDYLDSVLGSGNALKSRLTEVMMAQEFQDLS 172
WP_022775001       78 HGSELSQSLARMASAEdFS---VDR---------------ARALLM-VCGKFADRTARFAQDQAETLSDIMMAQDFQDLS 138 Candidatus...
jgi:Mpe_A2875      90 ETRRIAAA---------IV---ADP---------------VKAVASgSVMNFVSDVEAATARIDADLTDIMMAQDFHDLT 142
UCNUF:Cenrod_1300  92 ETRRIGAL---------LA---ADP---------------AAAVAQgHVAQFVAEVDRTSREIDQNLTDIMMAQDFHDLT 144
Q21S48             87 ETRRIGTL---------IV---KDP---------------VGAVAKgHVMNFLTDVEQSTQQIDQHLTEIMMAQDFHDLT 139 Rhodoferax...
WP_003077948       79 RTRAMRAE---------LI---KDP---------------VAAVAKgRVMNYLQEVEEGTEQTNSHLTEIMMAQDFHDLT 131 Comamonas ...
jgi:Daci_0601      79 RVRAMRAQ---------MV---EDP---------------VAAVAKgRVMNFLEEVEQGTQQADEHLTEIMMSQDFHDLT 131
WP_011806905       85 ETRRVVTS---------LV---ADP---------------VAAVAKgEIYNFLTDVERATQEADSHLTEIMMAQDFHDLT 137 Acidovorax...
1KMI_Z            146 GQVIKRMMDVIQEIERQLLMVLLENIPEQESrpk-----------reNQSLLNGPQVD-TSKA--GVVASQDQVDDLLDS 211
ACL06959          466 GQVIQKIITLIKDLESKLLNLVTKFGVkvskd-----------ktgeQQEELYGPS----HAQrdDAVHSQDEVDALLKE 530
jgi:Hneap_0719    173 GQLLMRVINLLEQLESKMVSLLHLTSPEITSgdrqkk----ggdsseDLQKGTGPALPkESS---DVVKSQDDVDDLLAS 245
WP_022775001      139 GQVIKKVVDIINRTEVQLVQLLLDSSPgastaespdpsatqtatmnvNDHRLEGPQTA-------DDALKQSDVDDLLAS 211 Candidatus...
jgi:Mpe_A2875     143 GQVVAKVVSLASDLEDSLVKLLVQAAPpeqa------------qkvvENTILNGPVVNpEGRT--DVVQNQGEVDDLLAS 208
UCNUF:Cenrod_1300 145 GQVITRVVSLAANIEEQLVQLLIVTAPpeaqgip------aqllaksTEHALDGPVVNaANRT--DVVQGQSEVDDLLAS 216
Q21S48            140 GQVIAKVVTLVANVEEQLVQLLIQTAPadavvkap-----thvaaagLKPVLEGPVVCpEGNP--DVVTGQSEVDDLLAS 212 Rhodoferax...
WP_003077948      132 GQVIARVVALAADLESQLLQLLIQTSPdtaqmpa-------lapveaAQPKLAGPVVDpENTT--DVVTSQSQVDDLLAS 202 Comamonas ...
jgi:Daci_0601     132 GQVIARVVSLAADLEDQLVQLLIQTSPnpqqta--------leplekPKEHLAGPVVDpEKTP--DVVTSQSQVDDLLAS 201
WP_011806905      138 GQVIARVVNLAATIEQQLVQLLIQTAPpqaqpp---------iapepRRDQLQGPVVNpESAP--DVVTSQSQVDDLLAS 206 Acidovorax...
1KMI_Z            212 LGF 214
ACL06959          531 FGF 533
jgi:Hneap_0719    246 LGF 248
WP_022775001      212 LGF 214 Candidatus Symbiobacter mobilis
jgi:Mpe_A2875     209 LGF 211
UCNUF:Cenrod_1300 217 LGF 219
Q21S48            213 LGF 215 Rhodoferax ferrireducens T118
WP_003077948      203 LGF 205 Comamonas testosteroni
jgi:Daci_0601     202 LGF 204
WP_011806905      207 LGF 209 Acidovorax sp. JS42
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