4COJ_A         72 EISkPHTYLYSLYRIWQKMKEMFGK--GVADEFVEAQINGAVYLHDRHHAAL-MPYCFAYTLKPIVEKGLPFiKTI---- 144 Thermotoga mar...
jgi:Mfer_1068 189 ANI-VHNSETIHKYVADEAFKQYALlrLLPSHLADAHMSGDIHIHDLEFFPArPLNCLQHDLRLFIRFGLKV-DGTgdht 266
O27582        196 ANM-IHNPETVHKYVADEALKQYTLlhILPSRLADAHMSGDIHIHDLEFFAArPLNCLQHDLRLFIRHGLRV-DGTgdht 273 Methanothermob...
WP_023991237  190 ANM-IHNPETVHKYVADEALKQYALlhMLPNELADAHLGGDLHIHDLEFFAGrPINCLQHDLRFFIRNGLKV-DGTgdht 267 Methanobacteri...
Q2NHG3        191 ANM-MHNPETIHKYVADESLKQYALlnILPHNLADAHMNGTVHIHDLEFFAGrPINCLQHDLRQFIRYGLKV-DGTgdht 268 Methanosphaera...
Q0W698        189 ANL-HHNPETIHKFAGDQILREYLLvqVLPKHIADAHMRGDIHIHDADYFAVrP-NCLQHDLSWFFENGLRV-DGTgkht 265 uncultured met...
BAI62900      200 ANL-HHNPETIHKFAGDQILREYLLvkILPRHITDAHLRGDIHLHDADYFAIrP-NCLQHDLSWFFQNGLRV-DGTgnht 276
jgi:Mvol_1467 190 ANL-MHNPESIHKWVADETMKEYALmkIFPKHIADLHMKGDIHLHDLEYAAVrT-VCCQHDLRPFLMHGLKV-DGTgrht 266
Q6M0P2        190 ANL-MHNPESIHKWVADETMKQFALlnVFPKYIADSHMRGDIHLHDLEYAAVrT-VCCQHDLRNFFKYGLKV-DGTgrht 266 Methanococcus ...
WP_013683031  123 ANL-QHNPETIHKLVADGVMKEYALlrILPLKLADSHMRGEIHIHDLEYFATrP-YCFQHDLRWFLKNGLKV-DGTgent 199 Archaeoglobus ...

4COJ_A        145 --KSEPaKHLSTFIQHVIQFVMFASNQSSGAVGLPdfFVWMWYFVkkDlkegiiPrdKLDWYIEQHFQILTYSLNQPI-- 220 Thermotoga mar...
jgi:Mfer_1068 267 svAAQP-KHLETLMNHCGEIMLAAQQNMSGGQAMSlwNIFVAPFV--E------G--LSYERIKQAVQMFIFNLNMAYaa 335
O27582        274 svAGPP-KHLETLMNHAGEIMLASQQNMSGGQAMSlwNVFVAPFA--S------G--LSYEKIKQAVQMFIFNLNMAYaa 342 Methanothermob...
WP_023991237  268 svAGPP-NHIETLMNHSGEIMLAAQQNMSGGQSMSlwNVFVAPFA--H------G--LPYQKIKQAVQMFIYNLNMAYaa 336 Methanobacteri...
Q2NHG3        269 svAGCP-NHIETLMNHSGEIMLAAQQNMSGGQAMSlwNVFVAPFA--A------G--LPYEKIKQSVEMLIFNLNMAYaa 337 Methanosphaera...
Q0W698        266 svAAPP-KHAMVAALHAAKILASSQTNMAGGQSLDnfNIFMAPFF--T------G--MSREEVKQVAQAFVYEMNMQYva 334 uncultured met...
BAI62900      277 svAAPP-KHAMVAALHAAKILASSQTNMAGGQSLDnfNVFMAPFF--T------G--MSYDEVKQVAQAFVYEMNMQYva 345
jgi:Mvol_1467 267 svSKPA-KNPEVAIQHAAKVLSASQCEMSGGQSIDefNVWLAPYM--R------G--LSYEEVKQLMQMFIYEMNQIYaa 335
Q6M0P2        267 svSKPA-KHPDVALQHAAKVLSAAQCEMSGGQSIDefNIWIAPYM--R------G--LEYSEVRQLMQLFIYEMNQIYaa 335 Methanococcus ...
WP_013683031  200 avAGPA-KNAEVAILHAAKALAAAQTNFAGGQGLDffNVWLAPYM--A------G--KSYREVKQLAQMFIYEMSQMYva 268 Archaeoglobus ...

4COJ_A        221 RTtQSPYTNFTYL-DRN----------------------------------YIKAIFEGerypDGSlitdhvediialqk 265 Thermotoga mar...
jgi:Mfer_1068 336 RGsQVPFTSINLElGVPeflqdetaygpggekv--gvygdyqdetkllakaFTEVLLEG----DAY-------------- 395
O27582        343 RGsQVPFTSINLEfGVPefledepaygprgeya--gvygdfaeearlltraFTEVLLEG----DAD-------------- 402 Methanothermob...
WP_023991237  337 RGsQVPFTSINLEfTVPdflkeepaygpkgrlv--gtygdfedetrmlqraFTEVLLEG----DSD-------------- 396 Methanobacteri...
Q2NHG3        338 RGgQVPFTSIGLEfTVPdflknepaygpggkvm--gvygdyekevrllqraFTEALIKG----DAE-------------- 397 Methanosphaera...
Q0W698        335 RGgQVVFSNVDIElTIPkyladkpaigpkgkvm--gtykdyqdelytftdaLLDVFIDG----DAL-------------- 394 uncultured met...
BAI62900      346 RGgQVVFSNVNIElTVPpflrdepaigpkgkvv--gtygdfedelqvfteaLLDVFLDG----DAR-------------- 405
jgi:Mvol_1467 336 RGgQVVFSTINLElEAPeflkdkpaikngqivg---tyeeydaeikiiaeaLTEVLMGG----DAY-------------- 394
Q6M0P2        336 RGgQVVFSSINLElEVPeylkgkdaikagqvvg---ayeeydyevkmiaeaLVDVLMDG----DAY-------------- 394 Methanococcus ...
WP_013683031  269 RGgQTVFSDIDIEyGVPsivadlpavlpggvqresvtygdfeeeaiafakaLTEVYLEG----DYV-------------- 330 Archaeoglobus ...

4COJ_A        266 hywewvsrereRQMFtFPVLTASLLYKdgkfLDE----DSARFINKINMKWQDTNWy-------IsdsIdaVASCCRLTS 334 Thermotoga mar...
jgi:Mfer_1068 396 -----------GKPHlFPNTIYVLRKEt---WDP----ELLEMVHELSAKYGTPYFlnmetsynN---VlvNAMGCRTRL 454
O27582        403 -----------GKPHlFPNTIYSLRREt---FRGef-dEELSLVHELASKYGTAYFinmladyrG---KmaNYMGCRTSL 464 Methanothermob...
WP_023991237  397 -----------GKPHlFPNTIYALREEv---LKDef-rEDLELVHELSSKYGTAYFtnmlpsyrG---QmsNYMGCRTSL 458 Methanobacteri...
Q2NHG3        398 -----------GKPHlFPNTIYYLRKEc---LTPef-tEDIERVHFLSAKFGTAYFinmlpkymG---NmaNYMGCRTRL 459 Methanosphaera...
Q0W698        395 -----------GKPHlFPNVIVKTRDSa---FKDpqqkELLFKVHQLFSKYGTPYIlnmlpdwqH---DavNSMGCRTRL 457 uncultured met...
BAI62900      406 -----------GKPHlFPNTIVKVRDSa---FKDpkqqEMLLKVHYLFSKYGTPYIlnmlpkwqH---GavNSMGCRTRL 468
jgi:Mvol_1467 395 -----------GKPFlFPNVIFKLRENa---FKNen-yELLYKIHRLSAKWGLPYFinmtadyqV---GntNAMGCRTRL 456
Q6M0P2        395 -----------GKPFlFPNVIFKLRENa---FKDen-kDLLVKIHELSAKWGLPYFinmfadyqH---GntNAMGCRTRL 456 Methanococcus ...
WP_013683031  331 -----------GKPFfFPKPNYKLRKEn---FRKegfdEFMILVHKCVAKYGTPYFlnllagylP---DnvFAQCCRLVL 393 Archaeoglobus ...

4COJ_A        335 StqtlkkfslsseeeEklkgrmnsiggsdlnIGSFKVITVNLPRIAL--ESggDREKYLQILRHRVQLIKKALAAVREII 412 Thermotoga mar...
jgi:Mfer_1068 455 Gtew--------tgnWead---------clrTGNLAYVTVNLPRIAYrsR---DDDEIYDYLHDYLRLAKEVLEIRREHA 514
O27582        465 Adnw--------tgdWekd---------clrTGNLAYITLNLPRIAYqsR---DDDELFEYLDEYIDMAVEVLRIRRSQA 524 Methanothermob...
WP_023991237  459 Sdnw--------tgdWeqd---------cfrTGNLAYVTLNLPRIAYqsR---DEEEIFEYLDSYLRLSEEILMIRREQA 518 Methanobacteri...
Q2NHG3        460 Sdnw--------tgdWekd---------clrTGNLAYVTMNLPRIGYnaR---DETEIFDYLDDYMKIVEDVLLLRRERA 519 Methanosphaera...
Q0W698        458 Sgdwadk---qgyenPgms---------tmrTGNIHYNTVNLPRIALeaNG--NDGKIFEILDSRLDLIREALEIKHDLV 523 uncultured met...
BAI62900      469 Sgdwadr---qgytnPrys---------tmrTGNIHYNTLNLPRIAIeaNG--DDNKVFEILDQRLDLIRESLEIKHELI 534
jgi:Mvol_1467 457 Sgdw--------gnsVeeg---------tlrTGNMQWYTLNLPRIAYeaKG--DDTRLFELLNERLHLVQDALLIKHSIS 517
Q6M0P2        457 Sgew--------gnsIees---------slrTGNMQWYTINLPRIAYeaDG--DDGRLFEILDEKLAIAKQALEIKHEIS 517 Methanococcus ...
WP_013683031  394 Spdan------dwedFakg---------cmrTGSLQVVTINLPRIAYesK---DDDELFELIEERMRLAREVIEIKAEII 455 Archaeoglobus ...

4COJ_A        413 KERISEGl-----LPLY------ENGLMllnrqYGTIGVTGVWESASIMglttediDGLKY--TEeGEVFVDNVLDTIRE 479 Thermotoga mar...
jgi:Mfer_1068 515 LKCLNQYn----iLPFLsqk-fdGEMYYrienaTMSFGFVGLNEMLIAH-------TGEGLe-DKySRRFGIKIIEEINK 581
O27582        525 QRCLDDYh----lLPFLsqe-idGERYYrienaTMSFGFTGLNEMLEYH-------LGAGIq-SPeANRFGLRVIEHINE 591 Methanothermob...
WP_023991237  519 LACLDDYn----lLPFLsqd-lnGDRYYrvensTMSFGFVGLNEMLKSF-------CGSGIe-DPdSLKLGLKVIDYMNG 585 Methanobacteri...
Q2NHG3        520 LKCLNDYn----iLPFLtqk-mgEDPYYmvdnsTLSFGFVGLNEMLLAQ-------TGAGLe-DKdSNNLGLKVIQHIND 586 Methanosphaera...
Q0W698        524 KKRLYENq----iLPFLtqkgrhGEDYYrfedlTHTVGFVGLNELVQAH-------TGSMLheSQdAYDFGMDVIRYMRD 592 uncultured met...
BAI62900      535 ERRLYDNk----lLPFLtqkgqsGEDYYqfkdlTHTVGFVGLNEFTKIH-------IGKGLheSRdAYDFGMDLIKYMRD 603
jgi:Mvol_1467 518 EKRLYGDdesravLPFLtqe-fdEDQYYrydntTKTFGFVGLNELLKYH-------MGEELhtSKdAVSFGEKVIGHIKG 589
Q6M0P2        518 KRRLYHDn----vLPFLtqe-fdGEQYYrydstTKTFGFVGLNELLKYH-------VGSELheSPeALAFGVKVISHIRK 585 Methanococcus ...
WP_013683031  456 KKRMEQNa-----LPFLtqd-vdGEPYYrvdkvVRSIGFVGLNEMLKAY-------MGEELh-ePsAWRFGLEIIKHMMD 521 Archaeoglobus ...

4COJ_A        480 EAEKGYHEYGFTFNIEQVPAEKAAVTLAQKD--RF------------------LFGekqpfeiySNQWVPLMANTDVLNR 539 Thermotoga mar...
jgi:Mfer_1068 582 KAQELRDETGWRWSVLQTPAESTAHRFAMLDieRFdavvqg-------tegayYYT--------NSSHIPVDSELDIIDR 646
O27582        592 RAAELKKETGWRWSVLQTPAESTAHRFAMLDheHYpeeavlq-----gtegayYYT--------NSSHTPVNAEVDLVEK 658 Methanothermob...
WP_023991237  586 RAQDLKKDTGLRWTIIQTPAESTAYRFAMLDreKFgkdavtq-----gdvgayYYT--------NSSHVPVDTSLNLAEK 652 Methanobacteri...
Q2NHG3        587 RANELKKETGLRWGVIQTPAESTAYRFATMDreKYpdqvicn-----gdsnasYYT--------NSSHVPVDTSLSLPEK 653 Methanosphaera...
Q0W698        593 WADSLSDITGWRWTLTQTPAESTAGRFARLDmkAFgaralvhg---drntggvYYT--------NSSHMPVDADISLFDR 661 uncultured met...
BAI62900      604 WAEFRTEMTDWRWTLTQSPAESTSGRFAKLDlrEFgdraivkg---dkekgnvYYT--------NSSHLEVDADVPMFER 672
jgi:Mvol_1467 590 YADGLKKETGLRWTVTQTPAESTAGRFARLDhkYYkeqtesvvngnlddmgsiYYT--------NSSHVKVNSDVTLGEK 661
Q6M0P2        586 YADDLKKETGLRWTVTQTPAESTAGRFAKFDhkYYpeetksvvngnlndlssiYYT--------NSSHVRVNADVTLGEK 657 Methanococcus ...
WP_013683031  522 IATEWSKETGLRWVITQTPAESTAHRFAKLDlmQFgdkavvqg---daergsvYYT--------NSSHCRVSANIPLFER 590 Archaeoglobus ...

4COJ_A        540 IRYSGKWDKKVSGGAILHINLGESFKTEEESFNMVK-MIADmGVMYFAFNTKISVCED-GH--AFYGerCPVCGkaK--- 612 Thermotoga mar...
jgi:Mfer_1068 647 LKIEQKFHPLTKGGHIFHVWLGESAPNPKGLMSLTEkICKRsEIGFWAYSNALSFCLRcKTlmRGLKdsCINCG--Ekd- 723
O27582        659 IRIEEKYHPLTPGGHIFNAWLGEAKPDPAALEGLTRrICRRsDIGFWAYSNALSFCLRcKTlmRGLQdsCARCG--Erd- 735 Methanothermob...
WP_023991237  653 IRIEEQFHSRTLGGHIFHAFMGESHSDPEALMSLTDkIARKsDIGFWAYSSALSFCVKcKTlmKGLQdsCASCG--Ekk- 729 Methanobacteri...
Q2NHG3        654 IRIESDYHPLTQGGHIFHAFMGESYSDPDSLMSLTNkITHKtDIGFWAYSSALSFCINcKTlmKGLQtkCTHCG--Etr- 730 Methanosphaera...
Q0W698        662 AKMEGKFHPVCNGGHITHLFLGEGTPDPAGLMSLTEkLCRNtSMGLFDYTRDLTTCRKcGTvaGGLLnsCPNCN--Angk 739 uncultured met...
BAI62900      673 ARLEGEFHPVCNGGHITHLFLGEGTPNPEGLMSLTEkLCRNtSMGLFDFTRDLTTCKAcATvsGGLQksCPNCG--Atga 750
jgi:Mvol_1467 662 VSIEEKFHPLCNGGHIGHFWNAEAYADPDVLMTITKkICDs-NIGFWTYTKNLSICEAcNKamTGLKdnCSNCG--Se-- 736
Q6M0P2        658 VGIEEKFHELCNGGHIGHFWNAEAYADPEVLMDITKkMTKt-DIGFWTYTKNLSICEKcSLamSGLKdnCTGCG--Sd-- 732 Methanococcus ...
WP_013683031  591 LRIEGSFHPLCNGGMMAHVWMGESSPNAELMWELTKkIATKtLIGYWAYTKDMTYCRRcKKvtGGIKsaCPFCS--St-- 666 Archaeoglobus ...

4COJ_A        613 -VDEYMRIVGYLVPvs-------aFNKERREiEYPRRQFY 644 Thermotoga maritima MSB8
jgi:Mfer_1068 724 eIEWYDRITGYVQQvgrakrasggWNKGKRQ-ELLDRRRi 762
O27582        736 eVEWYDRITGYVQQvgraksssggWNRGKQQ-ELLDRRRi 774 Methanothermobacter thermautotrophicus str. Delta H
WP_023991237  730 eVEWYDRITGYVQQvgrsksasggWNAGKMQ-ELRDRRRF 768 Methanobacterium sp. MB1
Q2NHG3        731 nVEWYDRITGYVQQvghaetasggWNAGKKQ-ELLDRKRW 769 Methanosphaera stadtmanae DSM 3091
Q0W698        740 dLEYYSRITGYCQRigsgd-saggWNDAKIA-ELRDRKRY 777 uncultured methanogenic archaeon
BAI62900      751 aLEYYSRITGYCQRigsgesttggWNDAKVA-ELRDRRRY 789
jgi:Mvol_1467 737 sVEKFSRITGYLQNvs-------nWNSAKQK-ELLDRKsn 768
Q6M0P2        733 hIEKFSRITGYLQNvs-------nWNKAKQQ-ELLDRKst 764 Methanococcus maripaludis
WP_013683031  667 dVECYSRITGYYQRvs-------gWNEGKQR-ELLDRRRv 698 Archaeoglobus veneficus