Conserved Protein Domain Family
TroA_a

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cd01148: TroA_a 
Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.
Statistics
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PSSM-Id: 238568
Aligned: 18 rows
Threshold Bit Score: 287.697
Created: 10-Jan-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding residues [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to PsaA from Streptococcus pneumoniae
  • Citation:PMID 9862808

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                            #          
NP_795286    23 YPVTVQSCDRSVTFTAAp-QRAVSNDVNLTKMMVALGLq--SHMVGYSGitgw---------nkpDQALLHdlg----nl 86  Pseudomonas syri...
NP_625292    58 FPVTIDNCGVKTTYDKPp-SRVVTIHQHPAELMLSLGLk--DRMAGTAFpd------------saVLPELRkdy---eai 119 Streptomyces coe...
NP_781610    52 SRHDDSVNKFSMVYDKKp-EKTLAITNAMIEMMLSMGLe--DKMAGTAYae------------nnILPELKasy---dkv 113 Clostridium teta...
NP_357209    33 YPLTINSCGQEITFKQAp-ARTVSVGQSTTEVLYLLGVa--DRVVGTALw---------------IGPVLKgyeeanakv 94  Agrobacterium tu...
NP_603782     3 KILFSFLLLSSLCFAKVp-QRAVSAAHFSTEILLSIGAe--KQMVGTAYpd------------neILPSLKeky---dki 64  Fusobacterium nu...
ZP_00127792  82 YPLTLENCGATLTFTHAp-TKAVTIGQAGTEMLYELGLg--DRLVGTSLwf------------nnVLPRFKaqn---dkv 143 Pseudomonas syri...
NP_562134    46 STYDQSGKEFQETFESKp-KRVISTNQTTTEIMLDLDLq--DSLVGTSFmd------------spILPRLEdky---kni 107 Clostridium perf...
NP_739286    38 DTISVDNCGDTVTFAGVp-QRVTLLDNPAVSTLAALGVl--DRVTAKAGlypteyyreevatqldQIPTLTdq------v 108 Corynebacterium ...
NP_781613    64 TNYNFAGEEIKVIFDKTp-EKVLTTNQTTIELMLDLGLe--KYLVGTCYl---------------DNPILDrladkykkv 125 Clostridium teta...
NP_821777    46 YPAILENCGVSEKFTKApgRVVVMNGASVAEVSTLLSLglgDRVVANQQsygmsevp-grakaikALPNGKv-------- 116 Streptomyces ave...
Feature 1                                                                                       
NP_795286    87 PELASKYPSLETLLNaNADFYFAGWNYgmrvg-gdvtpQSLAPLGIQAYELtescaqi--------mpraeatLADVYND 157 Pseudomonas syri...
NP_625292   120 PELAKKEPSFERVLEaEPDLVYGGYGSafaen-egrsrKAFTDAGIDTHLNreycg------------kkrvtMKDTYNE 186 Streptomyces coe...
NP_781610   114 PVMSKTYPSKEQIFAkGVDFIIGWGGDfndkg--igsiDWLNENKIKAYIPrsve--------------adatVDSIYED 177 Clostridium teta...
NP_357209    95 ERLADNDPSFETVVGkRPELITTQFQWqigpegvvgtpAQFAELGIPVYTSpadcvgkdnsgggdgvrntgftMELIYQE 174 Agrobacterium tu...
NP_603782    65 PVLSMKNPTKEQFYAvKPDFLTGWDSTvldkn--lgpiKELEKNGVQVYIMkslh---------------ssdINLVFED 127 Fusobacterium nu...
ZP_00127792 144 ERLADNEPSFEAVIGkRPELVAVQLEWmvgkqgvvgtrEQFHDLKIPTYILpsdcegkdnlvgadgtrlepfrIETIYKS 223 Pseudomonas syri...
NP_562134   108 NVLSETYPSKEAVLAlNPDLIMGWKSVfsdkn--lgsvESWNEKGVKTFIQrnsgi------------skeqtLDDVYYD 173 Clostridium perf...
NP_739286   109 DATGHLQIARETVVAtTPDLVIGSSDTvn--------rQTLRPNGIPLLDEpafcgs----------ldgevtFDDAWDQ 170 Corynebacterium ...
NP_781613   126 NVVSEKYPTKEQVLAlQPDLIFGWKSVfadkt--lgdvKEWNDRNVKTFAQrntvkt-----------vgnytIENGFKD 192 Clostridium teta...
NP_821777   117 KLNDAYDIPREAMIGlRPDLVLSTTSYgfdekngfatrDQLKEVGAHTYVSpqgcdq----------dtskmtVADSYTL 186 Streptomyces ave...
Feature 1                                                                                       
NP_795286   158 LLNLGRIFdVQTRAETLVAQMRRSVSDVQANVagk---tsPRVFLYDSGEDRPMTAGrl---aiPQALISAAGGHNimad 231 Pseudomonas syri...
NP_625292   187 IRTIGRIFgVSDRADKLVSKLQARVDKAATAVkge---paAPVFVYDSGDKTAFTAGgk---slGTEVIRLAGGKNvfgd 260 Streptomyces coe...
NP_781610   178 FKNLGLIFgKEDKAKEVTEKIKTELKETTDKIkgi--dkkVKVLGYDSGTDKAVIVGkg----iNNEIIKLAQGENifsd 251 Clostridium teta...
NP_357209   175 IRDLAKIFnVQGRGEEVVADLKKREEAARAKIasan-gklSAVFWFSSAELDIDPYVagr-ngaPGYIMSALGLKNvies 252 Agrobacterium tu...
NP_603782   128 ILTYGKIFnLENNAKKVVGKMKSDLAAVQKQLpk----nkVKVFTYDSGDKAPFVVGgd---siGNTIITLAGGDNifkd 200 Fusobacterium nu...
ZP_00127792 224 IGQLAKIFdVQDRGDALVTDLKARLSAAIANVrqnkandvSALFWFSSSDLASDPFVagr-kgiPDFMLNSLGMRNivqs 302 Pseudomonas syri...
NP_562134   174 INDIGKIFnIEEKSTKYVDDMKERINNISEKIksv---kePMKVLVIEGEGENKYRVygp-ktlVSDMVSKAGGTNva-- 247 Clostridium perf...
NP_739286   171 VELYGTVFgKEDVAAGYIAELEDRVEAVMKAVpgde-ertVAVLFPTPGSPATYAYGtg---smSHPLVTAAGLENvfad 246 Corynebacterium ...
NP_781613   193 INDLGTIFnIKDKTDKYVKELRDRLNKIEEKTsk----vkNKKKVLILGDKNKGEFRlygkndlVGDMVLKAGGENlg-- 266 Clostridium teta...
NP_821777   187 LRDMGKIFnVRDRAEQLIAASEKHIAEISAKVkgek-qpkVMVLFSNMAMGGNDFSSvva-kgiYNDILAKAGGSNafas 264 Streptomyces ave...
Feature 1                                                                                       
NP_795286   232 -vaasWTHVNWEsVVQGNPEVIVIVDYgevsa------aqkqhFLESNPALqsvdaiRNRRYVVLPYVAVTPGl-DNVSA 303 Pseudomonas syri...
NP_625292   261 -lddvFGDVSWEqVVERKPEVIAIYDYagagsv-----eqkkkFLLSQSALkdvpaiKNKRFVVLPLTATLVGv-RSAYA 333 Streptomyces coe...
NP_781610   252 -mnkaYTEVSFEeIIKRNPDVIMVLEYsvgnggm--tfedkvkTLKSNPALkdinavKNNRFIKVELTELYPGi-RVPQT 327 Clostridium teta...
NP_357209   253 --deeWPTVGWEtIAKANPTVIVAGKMdrrrfpad-diavkrkFLETDPVAsimpavKQGRVFDMDAQAMNPTi-RTIEG 328 Agrobacterium tu...
NP_603782   201 -ikkaWADGNWEkVLVENPDIIVIIDYgdqsa------eskikFLKEKSPIkdlkavKNNKFVVIELADITTGv-RNVDA 272 Fusobacterium nu...
ZP_00127792 303 --deeWPTVGWE-TIAKANPSILVIARmdrrrfpaddylkkieFLKTDPVTrnmdavKHDRIVIIDAEGMQAGl-RLFTG 378 Pseudomonas syri...
NP_562134   248 ---keSGSVGVEnIIEMNPDAIVLIHYlnqnkd-----nkeekALLENPALknvtaiKENKIIYTPLSETYAGg-ARTVE 318 Clostridium perf...
NP_739286   247 -eterVFEVTAEeLISRNPDVIIALHTdskvda----irtaarELPGAEALta---vRDDAILPMLLSYAEPPgpLAVDG 318 Corynebacterium ...
NP_781613   267 ---ekSGTMSLEnIVSANPDAIVFIHYgdekeih---daelakEFTENKALanvnaiKNKKIIITGLAETWAGg-VRTVD 339 Clostridium teta...
NP_821777   265 asktsFADLSKEkVAATDVDALVVIGYndpnpa-----ayakkLLKEFPQWpa---aKNNTYVALSDSMYLGP--SNDLA 334 Streptomyces ave...
Feature 1            
NP_795286   304 IETLA 308 Pseudomonas syringae pv. tomato str. DC3000
NP_625292   334 VEDLA 338 Streptomyces coelicolor A3(2)
NP_781610   328 VKKLA 332 Clostridium tetani E88
NP_357209   329 IETLA 333 Agrobacterium tumefaciens str. C58 (Cereon)
NP_603782   273 IKKLA 277 Fusobacterium nucleatum subsp. nucleatum ATCC 25586
ZP_00127792 379 FEELA 383 Pseudomonas syringae pv. syringae B728a
NP_562134   319 GIERI 323 Clostridium perfringens str. 13
NP_739286   319 LEQLA 323 Corynebacterium efficiens YS-314
NP_781613   340 AVERY 344 Clostridium tetani E88
NP_821777   335 VEKIA 339 Streptomyces avermitilis MA-4680

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