Conserved Protein Domain Family
DUF4349

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pfam14257: DUF4349 
Domain of unknown function (DUF4349)
This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 282 and 353 amino acids in length. There is a single completely conserved residue D that may be functionally important. The N-terminus contains a lipoprotein signal peptide sequence.
Statistics
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PSSM-Id: 464117
Aligned: 118 rows
Threshold Bit Score: 89.9152
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EIM56943                79 EKLVYTGNVDIQTL--EYEK---SVKSLKKKIEDYEGIIQKETqsssnydwytRDDNGQMDRRLSMSVRIPSKDFQKFVD 153
jgi:Cwoe_5807          199 RKVEQSSAIELGAPagKVDD---VAQDVLGVVARQQGIVDQSS-----------VATGGAGGEARFELRIPAARLQAALA 264
Q31KZ8                  56 PQLAKTATMQLAVQ--DVPT---AVRSAQAIVNREQGDILQQT------------ESSGDSPSATLQARIPADRLETAIA 118 Synec...
WP_015111017            76 PQLIKKAAIKIVVN--SVDK---SIDAVSQIIAKQQGDLIGLNe--------rQPTKENSRHTASIQLRVPQNSLEATLE 142 Nosto...
jgi:Srot_2261          101 QSMATEQVLAVQTD--DVQK---AKSQALKISHDAGGTTQEQKe---------QDATDKVPGWVQLTLKIPVDKVEDAVA 166
KUM09763                54 RDIVKTATMTVTVA--DSGDpvtAADKAAGIAGDAGGRVDSRTe---------YGGSASDPARVALMLRVPADKLDGVIE 122
jgi:Mvan_1502           59 RDVVKTASMTITVS--NPSE---AADEAAVIAERVDGRVDSRSe---------DAGSGTGRAMTSIVLRVPVAKLDEVVR 124
PRJNA231235:Y013_08125  55 RKEVVTGYLEMDAG--DPVA---TGRRVVTVVEEAGGRVDSLT--------------EQPEASSVLTVRVPADRLDEVVD 115
CCF61775                84 RKEVITGQIEIVSA--DPID---AAGKVTDQVTALQGRVDSRTe---------RPGTDDNVPSARLTVRIPAEHTEDFIA 149
Q5Z1C9                  85 RKEVVTGSVEITAA--DPIA---AAGRVADQVRAVDGRIDSRTe---------QPGTDDTDPSATLTVRVPTDRIDAFVD 150 Nocar...
EIM56943               154 SLSEQGQVM--STSVNTDNISQSYADTTAYVEGLEKEQKRLLEMMDKAQ---TIEEMIQVEDRLTEVETQLNQGKTSIAS 228
jgi:Cwoe_5807          265 QLSGLADAQvlARTDDTLDVNQAYVSVRRRLAGAEAERGALLRSLRAAD---TETETNRLRARLDGVERAIAGLQRSQRA 341
Q31KZ8                 119 AFRALGRVD--TVNVQAEDVARQLTDLQARLTNLERTERALQSILDRAT---KVEDVLKVTERLSSTREQIEQLKAEQLN 193 Synec...
WP_015111017           143 ELAKLGTIE--SRNITAEDVGDRLVDFQARLTNLRKTEANLQKIMDRAG---SVRDVLSVAQELSQVRQSIEQIDAQLKS 217 Nosto...
jgi:Srot_2261          167 KLRTLGDVK--YFTSHSTNVSQQSTDVSADIALVQQTIARLQQIYAQAAqsgKADDMVSAEKELIEQNDRLQQLKRQQQG 244
KUM09763               123 GLKGLGSVD--ALDVRAEDVTSRRVDLDARIKALQTSVDRLLAIMRDAR---DPSALIEAENALSQRQADLDSLRAQRAA 197
jgi:Mvan_1502          125 ELKALGTVE--TATTTAEDVTAQRVDLDARIRALQTSVDRLLAIMRDAR---DPEALIRAEDALSERQAELDSLRAQRET 199
PRJNA231235:Y013_08125 116 EICTLGRVT--SLSTTRDDVTMQYTDLEARVGALRASVDRLRALLESSA---DVEALIAAETALAERQAELDSLEAQRRQ 190
CCF61775               150 GLGDIGEVT--EVSTNRDDVTMQWQDLDARIKALQASVDRLRVLMSEAT---NTADLLAAEQALSSRQAELDSLTGQKRL 224
Q5Z1C9                 151 GLGGIGELT--RVSTNRDDVTMQWEDLDARIKALQASVDRLRALIAGAT---TTADLIAAEEALGSRQGELDSLTAQQRR 225 Nocar...
EIM56943               229 MDKDVDLSTVNITMEEVTRYDDikk-penFGQKVLKAFK---QSFSSFVTIVQELIIVLIM-LLPEIVVVLlIVLLIIF 302
jgi:Cwoe_5807          342 LDRRVDYSRVALTVRAVEGGGEddgaaftPGSALDDAGR--------VLAVTAGVAVIALAaLVPLALLAA-CAWPLAR 411
Q31KZ8                 194 LRTRVAYSTITLQFQSQI-LGEtal--paFAPELETAWRqssQSVLLLIRSLLVAGVWIVA-YSPLFLLLIgGGYGLLR 268 Synech...
WP_015111017           218 LQNQVAYSTITLNLEAAV-SSTspq--raVGSQIQETWNnstQSLGSFTVGLLKLGIWLMV-YTPYLLILAaGVYGVIR 292 Nostoc...
jgi:Srot_2261          245 LGGKVETTTVGVVLLGKKSAPPehgw-------vgsGLH---SGWSDLVATVKWLVTAISW-LAVWLVPLA-VVVVVAR 311
KUM09763               198 LGDQIALSTVTVDLVAPVAGGPapr----qyQGFFGQVE---RGWDALVDTGTHMFLLVGL-MVPWVGAAL-VLLVVVY 267
jgi:Mvan_1502          200 LGDQIAYSTVNVSFYAQTIGGPapd----qyNGFLGQVQ---RGWDAMVEVASGAVMLFGL-MLPWLGAVA-ILGAVIF 269
PRJNA231235:Y013_08125 191 LGDRIELSTLTVDITTDRLPSEq--------dSFWDGLV---AGWNSLWAALGAAVVGIGA-ALPWVAFLF-VCAGVLY 256
CCF61775               225 LDDQIALSTLTIEISSTRTEPEe------gPTNFWDGIV---SGWNSLVDWLKDAVVFLGK-ALPWAGFVV-VIGAVVW 292
Q5Z1C9                 226 LADQVALSTLTISITAADKGSRddg-----ptNFWDGVV---AGWHSLVDWLQDAIVFLGK-AVPWLGFLA-LLGALGW 294 Nocard...
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