Conserved Protein Domain Family
ABC_ModC_molybdenum_transporter

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cd03297: ABC_ModC_molybdenum_transporter 
ATP-binding cassette domain of the molybdenum transport system
ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Statistics
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PSSM-Id: 213264
Aligned: 9 rows
Threshold Bit Score: 318.855
Created: 4-May-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
  next features
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:Walker A, Walker B, Q-loop, D-loop, and H-loop form the nucleotide binding site

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                  ## ###                             
Q08381      1 MISARFSGRQgd------------fTLDAAFDVPGqGVTALFGPSGCGKTTVLRCMAGLTRLPGGHLVVNGVTWQEgrq- 67  Rhodobacter capsul...
NP_618774   2 TVEVGIEKEFygrknrkkkgenpsfSMNCSFDANS-DFVVLFGCSGSGKTTALRCIAGLENPDAGTIKINGTVYFDsrkk 80  Methanosarcina ace...
AAP77254    3 DIVFRFNKKLlgsk--------gafKLEIDKQLSFgEFIALFGKSGAGKTSILRVLSGLDKVENGYIRVGDTIWLDsqkn 74  Helicobacter hepat...
NP_661352   2 KLCIDIEKRLgd------------fSLKLKTEISG-ERVGIFGASGSGKSTLVHLIAGLIKPYAGEIYLDDTCLFSsrkk 68  Chlorobium tepidum...
NP_486473 248 EMLVDIEKHLps------------fHLKVAFTTDE-QPLGLLGGSGAGKSMILRCIAGIETPTRGRIVLNGRVLFDseqg 314 Nostoc sp. PCC 7120
NP_815120   2 RLIVDIQKELks------------hTLQIQFETKT-QTTGILGASGCGKSMLLKCIAGVETADKGQIVLNDQVLFDtekk 68  Enterococcus faeca...
YP_046549   2 NLNCQFEYRHdd------------fNLKVDLDLNQ-NLLGILGRSGAGKSTFLKNLVGVLKPTVGKIDFNHRLLVDtslq 68  Acinetobacter sp. ...
YP_013660   1 MLRLQFHKKLpf------------hDLNIDYTFEE-PVTAMMGASGSGKSTLFQCVSGLKSIDGGIIEFDGTPWDDsnis 67  Listeria monocytog...
YP_064202   4 TLCLDIRKKLan------------fTLDLSLVCPAgSLTAIVGPSGAGKSTLIRIISGLERPDHGTVSLDGVLWNDtcnn 71  Desulfotalea psych...
Feature 1                   #                                                                 
Q08381     68 -itPPHRRAVGYVFQEASLFTHLSVRENLVYGlrr------argPLRISEAEVTQLLGIDPLLRRPTATLSGGERQRVAI 140 Rhodobacter capsul...
NP_618774  81 vnlPPQKRKIGYMFQENALFPHMNVRQNIEFGlkgl-----ssmEKTDRVNEMLGLVGIEELEFAYPDELSGGQKQKVAL 155 Methanosarcina ace...
AAP77254   75 idlPPQRRRIGFVFQNYALFPHLNVYENICFGlk--------nkQDRIFADELVALMDLQSLKKAHIYQLSGGQSQRVAL 146 Helicobacter hepat...
NP_661352  69 idlSPEKRRISIVFQQATLFPHLGVKSNLLYGykrc-----rpsERRIRPEAIIEVLNLGHLVGRGVGKLSGGEKQRVAL 143 Chlorobium tepidum...
NP_486473 315 inlPSRDRRIGFLVQNYALFPHMTVAQNIAFGlpkk----lsdnSMRVQVEEQLIAMQLQGLGDRYPHQLSGGQQQRVAL 390 Nostoc sp. PCC 7120
NP_815120  69 inlSPQQRKIGLLFQQYALFPHLSVVENLTCVt-----------KDLQLVTQLLASFHLTKVQQQYPSQLSGGQRQRVAF 137 Enterococcus faeca...
YP_046549  69 mfmPTHQRHIALIFQQAQLFPHFDVRQNLEYGmrfh-----rnrVQKFSFDQIVDLLALDQLLNRKSLQLSGGESQRVSI 143 Acinetobacter sp. ...
YP_013660  68 lhlPVTERKVGYLFQNLALFPNMNVYENIAFGlkvkkkkkkeqaEIQQQVRKMSDYLQISHLLYSSVQKLSGGEKQRVAM 147 Listeria monocytog...
YP_064202  72 lciPPQDRGVGLVFQEYTLFPHLTVRKNVAFAa-----------VDKDCVQELLVRFGVDHIAERRPAGISGGERQRVAF 140 Desulfotalea psych...
Feature 1                  ##                                #                        
Q08381    141 GRALLSQPELLLMDEPLSALDRISRDEILPYLERLHASLQMPVILVSHDLSEVERLADTLVLMEAGRVRAAG 212 Rhodobacter capsulatus
NP_618774 156 ARALAPNPEVLLLDEPFSALDTVVRLKLRKELRDIQKRLKIPVIFITHDPVEAFTMADRMAVFEDGRVQQIG 227 Methanosarcina acetivorans...
AAP77254  147 ARALTSRPTLLLLDEPFSALDNAMAQILQNELKKIHKHFNLTTLLVSHNLSEIFSLASRTFVIKEGQIISDG 218 Helicobacter hepaticus ATC...
NP_661352 144 GRAVLANPRLLVMDEPLSALDDSLRYQIIPYLRSVSAEFGIPCLFISHSLTEMQLMTERVLVVRDGRLAGIS 215 Chlorobium tepidum TLS
NP_486473 391 ARALASQPEALLLDEPFSALDTHLRSQLEQQMTETLTNYQGVSLFVTHNMEEAYRICPNLLVLEDGSPVHYG 462 Nostoc sp. PCC 7120
NP_815120 138 ARMLAAQPAYLLLDEPFSALDAPLKEELQIELQQRLSNLNQHALIVSHSLDELYKLCQSLVIITKNQTLFGA 209 Enterococcus faecalis V583
YP_046549 144 GRALLASPDLVLLDEPLTGLDRNLKNQLLPFLNELKQQLNIPMIYVTHHPEELEYLHAPIVTMTDGILQYSD 215 Acinetobacter sp. ADP1
YP_013660 148 ARAMITEPKLLLLDEPFNGLDEETRLICMKLVGQMAKDFHIPVIFVTHYASEAEMMTEEILVMREGRLEKRK 219 Listeria monocytogenes str...
YP_064202 141 CQALARKPALLLLDEPFSALDVATRTNLRGELKKIKEILNIPVIHVTHDLEEAFYLADDICVVEEGRLAPQW 212 Desulfotalea psychrophila ...

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