Conserved Protein Domain Family
Pyr_excise

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pfam03013: Pyr_excise 
Pyrimidine dimer DNA glycosylase
Pyrimidine dimer DNA glycosylases excise pyrimidine dimers by hydrolysis of the glycosylic bond of the 5' pyrimidine, followed by the intra-pyrimidine phosphodiester bond. Pyrimidine dimers are the major UV-lesions of DNA.
Statistics
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PSSM-Id: 460778
Aligned: 81 rows
Threshold Bit Score: 53.8388
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
YP_004324221   1 MNIFVTDPcprksaQVLPDKHVVKMPLETCQMLSIVFshwyydwgddllkkkdgtpyktskgafrNHPCTQWAAKSly-n 79 
ORZ04279       2 VNNFLISQifsdtaKILDNKRLGKQRVETFQIINILDkkikkgnk-------------kkrigfvNHPAVKAWDGH---- 64 
AHH02019       2 VNTFILCSdfsesaSLLDDKRLFKQCVEARQIISILEesnls------------------kkgfsNHPATKQWIGY---- 59 
AWY04507       1 MMTWMPNKslfdsaEALELDQLAVATVEGASLFNEMLygeptd-----------------gqmkaPVPLIGMWAGY---- 59 
CEM10813       5 IVTYLPYAdyrrcaECMRKNDLQLQIDQSLDIFEQIStnafa------------------rsrydGHPCVEMWRAH---- 62 
WP_013336081   1 MQVFRPYIdhqrsaRFLDDLRLGKQRVETKQVILAILrklnvlk--------------dgkigwlNHPIVVMYFNNgrpy 66  Vulcanisaeta di...
WP_072710301   1 MQIFRVSPdhedsaKFLDNRRLSKQVLELYQIIRVCLgemglve---------------vntrylHHPVVKVVYNDgrpy 65  Salinicoccus al...
OAO32615       1 MQIFRVSPnhevsaKYLDNRRLSKQILELYQIIRVCLahmelie---------------gntkyiYHPIVQHVYNDgnpy 65 
SNV07499       1 MQIFRVSPnpnvsaEFLDNRRLSKQVLELYQIIRVCLgelgaiq---------------tgtgyrNHPVVKAVYNEgnpy 65 
AWY05216       1 MQTFLVa------pRNLDPKRLANQINECQSIWVALTegr----------------------gyiNHPATLMWDGY---- 48 
YP_004324221  80 TAWLIQHGCALSTEYTHR--YGKEHGCRD 106
ORZ04279      65 SDALKLYCNAMLEEWEHRg-FKNNMAYYD 92 
AHH02019      60 LDGLKYYFNCHLDEVFRRgrWNVKVMTIY 88 
AWY04507      60 EAALAAYVAACATTLVR---YGVSATNRA 85 
CEM10813      63 VPALVKYIRTLHGVYVEKg-YKTHRDDEM 90 
WP_013336081  67 LDDLIRYFYSVVDEWERRg-FVNKISLDD 94  Vulcanisaeta distributa
WP_072710301  66 LPDTLVMLEAMDEEHMRRg-GKRSLEFRD 93  Salinicoccus alkaliphilus
OAO32615      66 IIDTFQLLKEMNKEHIRRg-GKRSESFKQ 93 
SNV07499      66 LWGALEIMDAMNREHLRRg-GNQSEHFKN 93 
AWY05216      49 LIALAQYAVAMCEEHERRt-MSTHALHEN 76 
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