Conserved Protein Domain Family
ketoArg_3Met

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TIGR04543: ketoArg_3Met 
2-ketoarginine methyltransferase
This SAM-dependent C-methyltransferase performs the middle step of a three step conversion from arginine to beta-methylarginine. It performs a C-methylation at position 3 of 5-guanidino-2-oxopentanoic acid (keto-arginine). An aminotransferase converts arginine to 5-guanidino-2-oxopentanoic acid, and later converts 5-guanidino-3-methyl-2-oxopentanoic acid to beta-methylarginine.
Statistics
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PSSM-Id: 275336
Aligned: 9 rows
Threshold Bit Score: 503.814
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_014173219   1 MEALQPVRHFFLAQAIEFGLTSGLLDELAaDrtTDDRSSAEVAKRLSMDPDRLLGLLRYFAAEGIVRDPETSPRLTHKGE 80  Streptomyces bi...
WP_008742228  10 ISAIQPIRHFFLAQCIEFAMSSGLLTRLS-E--PSPTDVDGLAKDLNLHPERLTGLLRYLEGEGIVTDSEGVPAITAKGR 86  Streptomyces sp...
AGG35704      10 IEALQPVRGFALAQGIYHLFNSGLYERLA----DGPQEVPGMSASLGLDASRTSGFLRYLANENYLALSGDTVALTEKGR 85  Streptomyces ar...
WP_024511560  14 IEKLEPIRGFFLAQAIFHFFSSGLFDSLA----EKPKSVGTLAAEHRLNSDRLTAFMQYLGNENIVVFDGSIVQLTSSAR 89  Bradyrhizobium ...
WP_026128951   1 MEALQPVRYFVLAQVLHQFMETGLHEELN----AEPRTVGELSESLSLQSRRLEGVLHYLANEGYLSENDGVFSLEEKAR 76  Nocardiopsis pr...
D5FKJ3        19 IKGIEPIRQFVLAISIYHLFDTKLFSLLI-K--HEVASPEVACNELGMEKEKLLGLFRYLKNEGILLETIDGFSLSKEGH 95  Pseudomonas syr...
WP_026719030  11 IDAIQPIRFYVLATSIYHLFDTGIFDILC-Q--NGESSIKNLGKEKGLEQDKLSGFLKYLKNEGIVDEREGCFSLTAKGK 87  Fischerella sp....
EYF01039      12 IDAIQPLRHYVLSINLYHLFETGLFASLS-E--KGSLSPAQIAELHGMDASRLRVFLGYLRNEGYLKEVDGKFSLSDQGR 88  Chondromyces ap...
WP_025990235  14 VSAIDPIRGFVKATMIFHFFESEVFDYLL-R--SGWARVDAIAEDMKMNKRKLKGFLDYLVNEDLMVRKDKEYLVSKRAI 90  Burkholderia ok...
WP_014173219  81 EARRFRPWYELLIGGYSATLRELPAVMADPSAYAGRDGGMVGLGSCGISRHDAIPLVRRLLALLPEEPAVVVDLGCGDGS 160 Streptomyces bi...
WP_008742228  87 ELLEFRPWYELLIGGYGATLRELPEVMADRKRFASRNGTMVGLGSCGMSRFDAVPLVKRLITRLPEPPSALVDLGCGDGT 166 Streptomyces sp...
AGG35704      86 ALGPYRPWYELLVGGYAETFQQITDVL-NGKGYATRDGRLVGIGSCGMSAYDALPLVRELMSDLPAAPASVVDLGCGDGT 164 Streptomyces ar...
WP_024511560  90 EFGQYRPWYELLVGGYAETLLQISDTL-CGAGFASRCDRLVGQGSCGISEYDAIPLVQNLLTRLPSAALEIIDLGCGDGR 168 Bradyrhizobium ...
WP_026128951  77 ETAVFSSWYKLLVGGYSQTFEQLGRTLQQGAGFASRSGLDVGVGSCGISQYDAYPVIVGLLGEVRDDVESVVDLGCGDGS 156 Nocardiopsis pr...
D5FKJ3        96 ALAPFEGWYVMLVGGYATTFLQMGERLQEGAGWATRDATKVGVGSCGISHFDAIPLTRSLMAQAPGTCTKLLDLGCGNGR 175 Pseudomonas syr...
WP_026719030  88 SLSNFRGWYTMLIGGYGQTFLQVGEKLKKGAGWATRDATKVGIGSCEISHYDAIPLTRDLIAEIPKSCRRLLDLGCGNGL 167 Fischerella sp....
EYF01039      89 RIEEFRPWYTMLVGGYNETYMQVGEKLKQGSGWASRNLEQVGTGSCGISRHDAIPLTRSLMAKVPGKCTRLLDMGCGNGR 168 Chondromyces ap...
WP_025990235  91 EINKFRGWYTMLIGGYGKTFLQMGSCLPVDADWAARDAAKVGIGSCGISHYDAIPLTRSLVAKAPGNKKNFLDLGCGNAM 170 Burkholderia ok...
WP_014173219 161 FLLEICADRGR---GIGIDPDASSIARARALSRDQGRGAEMTFDVSTAQDFLSr-kLDLPHRSVCFITA---FSLQEVLE 233 Streptomyces bi...
WP_008742228 167 FLLDLCEGGSP---GIGVDPTAGSIDNARRAAAERGMSDQVSFVNATAEDYMAq-vKAEAVGAPCFVTA---FSLQEVLE 239 Streptomyces sp...
AGG35704     165 FLAGLVDGSGTv-tGIGIDP----------YAPEESPAEGLRFVRSGATDYLRe-aDTPESGPDSSQIClaaFLLQEVLE 232 Streptomyces ar...
WP_024511560 169 FAARILDGLPDs-nGIGVDVSP----------PETSPHERLKIEQASALDYVQrlaPRLQSEPPSVVVVa--FVLQELLG 235 Bradyrhizobium ...
WP_026128951 157 SLADLMELLPGl-sAIGVDPEPESVRAGEDLMRRRGLADRVRLRVAGAENAPE---LDLGPGPVCFISA---FVLQELLE 229 Nocardiopsis pr...
D5FKJ3       176 YLAEFCKALPQi-qAWGAEPDRGGFEEAVDLIEKEGLSHRVHISHSGAVEFLD---SDFDFEPDFIVLG---FVLHEILG 248 Pseudomonas syr...
WP_026719030 168 YLVDFCKAFPEi-eAWGVEPDEGSYRAATELVRQVGLQNRIKLTRNSAVEFLH---SDFNYQPDFIVMG---FVLHEILN 240 Fischerella sp....
EYF01039     169 YLVDFCEALPEiqaAWGVEPSAESCREAAQMIARHGLQDRVHIVNASAGEFLR---SGMGIEPDFVVLG---FVLHEILG 242 Chondromyces ap...
WP_025990235 171 YLAEFCRAIPEi-yALGVEPDRGGYEAGLAIIKKNELESRVSLINMGAIEFIN---SGFDFNPDFTVLG---FVLHEILG 243 Burkholderia ok...
WP_014173219 234 QRDRGAVVGLVRSALEQAPESYLIVVEVDHRPTDPAVMRHGLGLAYYNPYYLLHQVTEQRLETAEFWRDLFTEAGGSVVE 313 Streptomyces bi...
WP_008742228 240 QQGRGATVEVVRTALASAPGAHLAIVEVDHRPLDPAVLRHGLGNAYYNPYYFLHRITEQRLETRGFWEELIAEAGGDVVA 319 Streptomyces sp...
AGG35704     233 QEGRGAVVELVRAALRR--SGHLAVVEVDHRPADPQVMRHGLGLAYYNPYYLLHVLTEQRLESDAFWRELFQEAGARVVT 310 Streptomyces ar...
WP_024511560 236 QAGRPTVVEFLRTL--RVKGRFVAVVEVDYRPTDPRVMRHGLGRAYYNPYYLLHNLTAQRLAPIDFWEALFLEAGFRPIA 313 Bradyrhizobium ...
WP_026128951 230 QQGREAVLGLVREVFTHHPDAHWIVIEVDNRIADRAAMAHRLALSYYNPYFLVHYLTEQRLERDAFWHELFAEAGAEVAQ 309 Nocardiopsis pr...
D5FKJ3       249 QAGRPAVVNFLKKIVHRFPAINLIIIEVDNQFDNAGAMRHGLALAYYNPYYLLHCFTNQLLVQDADWLDIFAEAGLSLVT 328 Pseudomonas syr...
WP_026719030 241 QEGEAGIVNFLLQITKRFPDIYIIVIEVDLKIDAPTIMQHGLSLAYYNPYYLLHYFTNQRLETQLFWEQLFAKCQLDLIA 320 Fischerella sp....
EYF01039     243 QEGAAGVRAFLTQMVARFPDLHLIIIEVDQQMDSARAMQHGLGIAYYNPYYLAHPFTQQCLETQPFWEGLFAECGLEVVA 322 Chondromyces ap...
WP_025990235 244 QSGRSGVVGFLRAIIDRFPCVKIIVIEVEDRIEEQKIMQHGLSLAYYNPYYLLHYFTEQHLVSDEVWLEIFDEAGLSVLA 323 Burkholderia ok...
WP_014173219 314 CLTTDPEVDSTGLELGFLVRK 334 Streptomyces bingchenggensis
WP_008742228 320 CLTTAPEVDSTGLELGFLVRG 340 Streptomyces sp. Mg1
AGG35704     311 RRVADPRVDSTGLEVGYLLTR 331 Streptomyces arginensis
WP_024511560 314 SGEVSFEIDSTGLEFGRLLSP 334 Bradyrhizobium sp. ARR65
WP_026128951 310 QLTADPRVDSTGFLLGYRLRV 330 Nocardiopsis prasina
D5FKJ3       329 RETTSDQVDSTGLEIGYLLRR 349 Pseudomonas syringae pv. syringae
WP_026719030 321 KKTTDIQVDSTGLEIGYLLKR 341 Fischerella sp. PCC 9431
EYF01039     323 KEYTDPQVDSTGLEVGYLLRK 343 Chondromyces apiculatus DSM 436
WP_025990235 324 KETTSPHVDSTALEIGYLLMR 344 Burkholderia oklahomensis
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