Conserved Protein Domain Family
NhaP2

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COG3263: NhaP2 
NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains [Energy production and conversion, Inorganic ion transport and metabolism]
Statistics
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PSSM-Id: 442494
Aligned: 261 rows
Threshold Bit Score: 358.268
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012031461   2 TNLNILYLVFSMLLFISVIGSTLSARSGIPLLVLFLVIGMLAGEEGIIGIRFNQFFFANLLGQAALAVILLDGGLRTSLT 81 
WP_011139549   2 DNLELYLLISALLMLLSVVSSKLSDKFGIPALFIFLGLGMLAGSDGILGIYFDNAKLAQSVGTLALIFILFGGGLDTSWK 81 
WP_014585711   2 IPFEYLLLGVAVLLLLSVVSSKASTQLGVPALLLFLVIGMLAGADGPGGVDFDNPWLAQALGTVALIFILFSGGLDTRWS 81 
WP_007315655   3 PSIEYILLVIAVLIIVSILANKVSGRLGVPALLIFLLVGMLAGSEGPGGIYFDDPWVAQAVGVIALTFILFSGGLDTRWS 82 
WP_014770331   4 ENLEWYIVIIAFLMLVSVISSKISDKFGVPTLFIFLGLGMLAGSDGILGIHFDNPNLAQSIGTIALIFILFGGGIDTSWK 83 
WP_015284743   2 IAIEYVLAGAAVLILFSIIANKVSGRLGLPALLIFIFVGMLAGSEGPGGIYFDDPFIAQSIGVVGLALILFSGGLDTRWT 81 
WP_128699287   3 VSIEFILLWVSVLILISIFSSKLSDKFAVPALLLFLIIGMLAGFEGPGGIYFDDPYLAKTIGIIALIFIIFSGGLDTSWK 82 
WP_128699371   1 MAFETILLWASVLMFVSVVSSKISDKFAVPVLLLFLAVGMLAGSEGIGNINFDNAQLAKQIGILALIFIIFSGGLDTNWK 80 
WP_128700837   1 MAFETILLWVAVLIFVSAVSSKLSDRFAIPALLLFLVIGMLAGSEGIGRVYFDNARLAKSIGVIALIFIIFSGGLDTNWK 80 
WP_074175677   3 IALEIIFLGISLLFLVSIIANKFSERLGVPALLIFLIVGMLAGSEGPGGIPFDEPAVAQIIGIIALAYILFAGGFDTRWD 82 
WP_012031461  82 NIRIAYKPALPLATWGVIATAVISGLFITWILakygyieKGNWRYGMLMASIVGSTDAAAVFSLLRNGGVRLNARVQSTL 161
WP_011139549  82 AIKPVLGAGLALATFGVIFTALFVALSVRYLL-------DFTWQESLLLGAIISSTDAAAVFAILRAQGISLKKRLAPLL 154
WP_014585711  82 EVRPVLWRGVLLSTVGVLITTVIVGYAAYYVL-------DFSLLEALLLAAIISSTDAAAVFSILRSRQIRLKGELRPLL 154
WP_007315655  83 EVRPVLPQAAVLSTLGVLLTALLMAGIAIVVF-------GVSLLEGFLLGAVVSSTDAAAVFSILRTKRASLKGILRPLL 155
WP_014770331  84 VIRPVIKEGLLLSTLGVLLTALLTALCVHYLF-------HFNTLESLLVGAIVSSTDAAAVFAILRAKGIALKRPLAPLL 156
WP_015284743  82 EVRPVLYKGLMLSTVGVALTALVVCAAAIFLL-------GFSPLEGFLLGAIVSSTDAAAVFSILRSRRASLKGDLRPLL 154
WP_128699287  83 EIRPVALPGFFLATAGVFLTAFIVGVFSVFIL-------KFSLLEGLLLGAIVSSTDAAAVFSVLRSRHISLKSPLKPML 155
WP_128699371  81 DTRPIILPGIVLSTLGVLVTAIITGLFAVYVL-------KFSLLEGVLLGSIVSSTDAAAVFAILRSRRISLKKPLKPLL 153
WP_128700837  81 DTKPIVWPGIILSTLGVLLTAVITGFFAVYIF-------KFSLLQGMLLGSIVSSTDAAAVFSILRSKRISLKQPLKPLL 153
WP_074175677  83 EVRPIFWPGVALSTVGVVLTAVCLGAFASLVL-------GLSPLTGFLLGAVVSSTDAAAVFSVLRMARARLKGNLRPFL 155
WP_012031461 162 EVESGANDPMAILLVTAFISLNLHPeEQNLLSFSTLLITQFALGILIGLTSGYLLARLLQRLHL-PEGMYAILIFSAGIL 240
WP_011139549 155 ELESGSNDPMAIFLTVAILQMILLPeSSSLGEWIGKFFLQFLVGGIMGYLFGILLPPIFNRIHLgHYGLYPVFSIAWVLL 234
WP_014585711 155 ELESGSNDPMAIFLTISLIGLIAAP-ATSPTALLPIFAQQMALGAVCGHMMGRAMAIAVNRIRLdYRGLYPVLTISLVLF 233
WP_007315655 156 ELESASNDPMAVFLTIGAITLLLNP-GLSPLIIIPLFIQQMAVGGLIGYGMGKAMVYLINRLKLeFEGLYPVLTLALVMM 234
WP_014770331 157 ELESGSNDPMAIFLTLSVLQLIAIPhELSFSELIFSFFLQFLIGGLLGYLFGFLLPLMLNRLHLgYYGLYPVFSIAWVLL 236
WP_015284743 155 EFESGSNDPMAILLTIGAITLLMQP-GTSFFSLVPLFVQQMAVGGLLGYGMGKGAAWLINAVKVeYEGLYAVLTLASALL 233
WP_128699287 156 ELESGSNDPMAVFLTLSFISMLTVK-NIGVIALTSRFVLDMGGGALVGYAMAKMSVWLIGRLKLeYDGLYPVLTVSLVLL 234
WP_128699371 154 EFESGSNDPMAIFLTMGFLSFLTVK-GSGLVLLIPRFVLDMGMGALVGYLMAKAIVFFIKRLKLdYEGLYPVITISLILF 232
WP_128700837 154 EFESGSNDPMAVFLTVGFLAILTAK-NMGIAALIPRFFLDMGMGAVIGYLMAKVIVYSINRLKLyYEGLYPAVVISLILL 232
WP_074175677 156 EFESGSNDPMAVFLTTGVIALILTP-GASVLTLVPMFVQQMVVGGLLGYGMGKAIVFLINRLKLeSEGLYPVLTLAMVLM 234
WP_012031461 241 TFSMTNLLGGSGFLAVFIAGIVIGNHHVRATEHVLRVMDGMAWLSQAVLFVMLGLLITPSQVVKILPLVAVISLFLIFIA 320
WP_011139549 235 LFSASSFLGGNGFLAVYIAGIASNAREFVHKKNLIGFHDGLAWIMQIAVFLTLGLLVFPSDLPAIAPAAIGISLWLIFVA 314
WP_014585711 234 TYGLAAILGGNGFLAVYLAGLTLGNYSFIHKRSLMHDHDSLAWMMQIVMFLTLGLLVYPSQLIPVAATGLFVCFILIFVA 313
WP_007315655 235 TYGVTASLGGSGFLAAYIAGLVLGNSMFIHKNSLMRFHEGIAWLMQIAMFLTLGLLVFPSQLVAIAGVGILFSLFLIFIA 314
WP_014770331 237 LFGGTVMLGGNGFLAVYIAGIAANAKEFTHKKNLVGFHDGLAWIMQIWVFLTLGLLVFPSELPNIAWQSILIALWLAFIA 316
WP_015284743 234 IYGLTTIVGGNGFLAAYIAGLVIGNSAIVHRKSLIRFHEGIGWLMQITLFLTLGLFVFPSELLPVLVPGIIISIVLIFVA 313
WP_128699287 235 TYSLAALLQCNGFLAVFLVGLIMGKHEFLNKKMIMRFHDGLAWLMQIVMFLTLGLLVFPSHLLPVMGAGLLIAIVLMVLA 314
WP_128699371 233 TYVIAVLLKGNGILAVYLAGLGLAQAEFPNKKSIMKFHDGLAWISQIAMFVTLGLLVYPSHLVPLIGTGLLVTIVLMFIA 312
WP_128700837 233 TYVIAVFLKGNGILAVYVAGLMLGQADFPNKRMITRFHDGLAWLMQIAMFITLGLLVFPSHIIPLIGPGLLLTFLLMVVA 312
WP_074175677 235 TYGLTATFGGNGFIAVYVSGLVVGNSIVVYKKSLIRFHDGIAWLMQIVMFLALGLLVFPSDLVPVIIPGLLIAFFLLLIA 314
WP_012031461 321 RPLAVISVLIFC-RFNPREIGFISWVGLRGAVPITLAIIPIMENVPNARFLFDLTFGVVIISLVLQGMTLPFAAELFKVK 399
WP_011139549 315 RPLGVFLTLTFS-SLSLQEKSFISWVGLRGAVPIILATYPFLAGLESSSLIFNTIFFIVLTSILIQGTTLPRVAKWLKVE 393
WP_014585711 314 RPVSVLLCLLPFrKMRFAERIMISWVGLKGSVPIILATFPLTYGIEKADLIFNIVFFVVLTSVLVQGSSIPFLARWLEVD 393
WP_007315655 315 RPVAVFISLSPW-KMALRDKVMVSWVGLRGAVPIVLATFPLIAGIQHAEIIFNVVFFIVVTSALLHGTSIPFVARHLGVS 393
WP_014770331 317 RPVGVFLTLLGS-FLTVKEKLFISWVGLRGAVPIVLATYPFLQNLEHASMIFNTVFLVVLISLLMQGMSLPWMARLLGVE 395
WP_015284743 314 RPIAVYLSLLPW-KMKKNEKLMISWVGLRGAAPIVLATFPLIAGVPQAQVFFNLVFFMVIASALLHGTSIPFVAKHLGLA 392
WP_128699287 315 RPVSVLMCLLPF-PMVLRKKIMVAWVGLRGAAPIVLATFPLLAGIPQADTIFNVVFFVVLTSVLIQGTSIPLVSRILNVD 393
WP_128699371 313 RPLSVFLCLLPF-KFAVPKKIMLSWVGLRGSVPIILATFPLAAGIPQAETIFNIVFFIVIASVFIQGTSIPLVSKLLKLD 391
WP_128700837 313 RPVSVLLCLLPF-KMNMRKKAMVAWVGLRGSVPIILATFPFMAGIAQADSIFNIVFFIVIASVLIQGTSIPVVAKVLKLD 391
WP_074175677 315 RPIAVFITLLPW-KMPLNEKALVSWVGLRGAVPIILATYPLVAGVPDAEMIFNVVFFIVLVSALVHGTSIPTVARWLGLA 393
WP_012031461 400 IPPSAHPSNEHEIWVGDRASIRIYEFNVKKGAFGINQHPDAISrrlGEEEIRLFALVRQDKVEAVTPQTKIRVGDRLWYA 479
WP_011139549 394 ESKESKVPEP-SIIASPLLHHTLKQFYITKNSSVIGKSIAELE---LPSEFLILLIKREKEQIKPTGSTLFEEGDMLLIQ 469
WP_014585711 394 APAKPSTALS-EMAAGGGIREPLVEFEVMPGSAAVGKQIADLN---LPDDTWIAILRRDGRPLRPGGSTVLQAGDGLSVQ 469
WP_007315655 394 DPMQETSRLAMSLGDGYESGNDLIELTISGQAGVVGKQIVDIG---LPPGTLIIMIEKGGNRYVPCGSTVLEEGDHLLIL 470
WP_014770331 396 EPQEKSALTN-NVAASPLFYHAMRQLYVEENAEVIGKSLAELD---LPSEFLIVLIKRQGKSLKPTGSTLFHANDLLLVY 471
WP_015284743 393 APLPGRSRFGLELDSPEDSRNELFELVVPHGSPASGKQIVNLG---LPAGTLIILIAKGSEQFSPRGATVLEDGDTLLIL 469
WP_128699287 394 APMANKRRYPIEFEKIEGIDAELTDLIVPYVSEAVGKQLMELN---MPGKCLIVLISRGDRYIIPAGQTVIEGGDVLLVL 470
WP_128699371 392 VPLPDKKAYPIEFEKVEGIDAELTDVIVPYNSEAIGKMIKELN---VPVKCLIMLVSRNDKFVIPSGSTVIEGGDVLLVL 468
WP_128700837 392 LPWTNKTRYPLEFEKTEGIDAELTDIIVPYNAGVVGRPIIELS---VPPDALIVLISRNDKFIIPNGYTIIEGGDVLLVL 468
WP_074175677 394 APLQEKRKLSREFEVDPNTPSELIELTIPPDASAVGQQVVDLG---LPEGALIILMQKESERFVPSGSTVIEAGDTLLLL 470
WP_012031461 480 VNGDH-AHALAVVLND-TYVTR 499
WP_011139549 470 CEDPAlFRQIVRSFAPlES--- 488
WP_014585711 470 SSGPS-LELLRSQVEK-Raaed 489
WP_007315655 471 TNQLQ-SDKVRSMFIS-Ersad 490
WP_014770331 472 CDPKElYETISKRFSA------ 487
WP_015284743 470 TTPDA-AQAVRRIITG-ETeme 489
WP_128699287 471 ANEHD-LAALQKKLAS-LREED 490
WP_128699371 469 ANAED-FSVLQCALAR-LKE-- 486
WP_128700837 469 ANQRD-LTMLQNIFSQ-LAQ-- 486
WP_074175677 471 TTDDL-VESVRARFLE-Iregk 490
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