Conserved Protein Domain Family
MoeA_like

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cd03522: MoeA_like 
MoeA_like. This domain is similar to a domain found in a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. There this domain is presumed to bind molybdopterin. The exact function of this subgroup is unknown.
Statistics
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PSSM-Id: 239599
Aligned: 46 rows
Threshold Bit Score: 260.942
Created: 23-Mar-2006
Updated: 9-Sep-2024
Structure
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Aligned Rows:
 
putative MPT
Feature 1:putative MPT binding site
Evidence:
  • Comment:annotation is based on homology to related subgroups

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                       
ZP_00668460 213 GRSMLHDMTQilpgkskgaaFRRGQQISVGDLCRLQQMGRQRVYVDqgntpdgewIHEDQAALAFaramageg--vrfve 290 Syntrophobacter ...
EAO23581     11 GQVLGHDIIKiipgrekcraFRRGQIITAADVPLLQDLGKEHIYIWeag---eelIHEDEAALRLaqsasgp---ginls 84  Syntrophomonas w...
ZP_01150030   2 GKILSHDITKivkdefkgpaFKKGHIIQTQDIEEFLKLGKEHVYVLele---ggeIHEDEAGSRLaraaaga---gvrcs 75  Desulfotomaculum...
ABA87480     12 GKILSHDITRivpgelkeraYKKGHMITDEDVPKLKQLGKDHIYILnla---eglVHENLAAERIaraicgp---flgyg 85  Pelobacter carbi...
ABC19249     12 GCVLAHDHTKivpgqfkgrrFKKGHIIQPEDVAELLQMGKEHIYVLnlg---pdeVHEDEAALRLaraaagdgdhgldfs 88  Moorella thermoa...
ZP_00558671  11 GSVLMHDLTQiipgktkdarFRKGHVIKEEDIPTLLSMGKEHIFVWdqt---pglIHEDEAAERLakavagp---glsfs 84  Desulfitobacteri...
ZP_00676353  12 GSVLFHDITRivpgefagraFKKGHIIREDDVAALLKLGKDNIYVLdle---egyIHENEAAQRIaravcgn---girit 85  Pelobacter propi...
CAG35000     43 GMVLCHDMTRivpgeckgpaFKKGHVVTEEDIPTLLEIGKEHIFVLdme---kgrIHENEAAERIakaafgp---gitls 116 Desulfotalea psy...
CAG36450     11 GTILCHDVTRiipgktkevaFRRGHLIKEEDIPELLAIGKENLYIYdpa---dgyLHEDDAAIRIseavage---gills 84  Desulfotalea psy...
EAT05203     12 GMVLPHDITEirggefkgraFKKGHVIRAADIEHLKRLGKEHIFILelg---agdIHENEAAALLaaalagpg--tmtgg 86  delta proteobact...
Feature 1                                                                                       
ZP_00668460 291 ppREGKINFVAdrDGLFLVEEESLEEFNMVagVMCASRRGYTLVRNGRMLGGTRAIPLYLPRSAFMKALAVlry--gpLF 368 Syntrophobacter ...
EAO23581     85 epSHGRVNLIAayDGLLKIQVDQLHWINNLdsVIFATLHNNRTVVKEQKLAGTRVVPITVERSLVEEAEKLcsn-prpLV 163 Syntrophomonas w...
ZP_01150030  76 qpKESRVNLFAecAGLLKINLDALDAINDLpdVILSTLPNHSVVKEGDMLAGTKVIPLVIKEEILAQAERIink-agnIL 154 Desulfotomaculum...
ABA87480     86 epNQGKIELTSelNGLLKINIPLLQKLNEIpdVTIATRLTNQPVGVGSTVAGTRIIPLFTQEENLLRLESLcsk-hppLI 164 Pelobacter carbi...
ABC19249     89 epQEGKVNLEStrNGLLKINLEALKQVNSVadIMLATLHNNYPVTAGQVVAGTRLIPLVAPRSVIERVEAIcre-aggIL 167 Moorella thermoa...
ZP_00558671  85 etKEGKVNLIAeeDGLIYASEEGIYALNSLeyIILATLHNHRPVKKGQKIAGTRVVPLMIDENVVIEAEGIarrfeepIL 164 Desulfitobacteri...
ZP_00676353  86 epSEGKVTMEAveQGLLKVKVDALNRINDIeeMVLATLHTNRLVDTDTRVGGTRIIPLFTDEERIRRVEAIaqa-afpLI 164 Pelobacter propi...
CAG35000    117 dvSEGRVNFEAs-PGLLDINVEALNRINSIeeVVLATMHSGQQVTEARAVAGTRVVPLVIDEEKIERVEAIcae-ypyVV 194 Desulfotalea psy...
CAG36450     85 ppSEGKVTVKAarRGLLRIDVDALQQLNMIdnVICSTIHNNQVVAEGRSLAGIRVIPLVIDGAVVAEAEALaa---qpLL 161 Desulfotalea psy...
EAT05203     87 epVEGKIEIKAahRGVLRVAREALYQFNLLgeVMAATLHGDGLVEEGEQVAATRLIPLVGSRRVVEQAAALaar-eggIV 165 delta proteobact...
Feature 1                                                                                  ###  
ZP_00668460 369 RVLPMrkaRVGILVTGSeVFQGLieDRFIPIIGAKVEalDCKVVKAVIVPDDrVAIRDGVHELVragaDLLVTTAGLSVD 448 Syntrophobacter ...
EAO23581    164 LVKPFknlWTAVITTGNeVCYGRikDGFGRVIRKKITpfGGRFMSQTIVPDSpEIIAAEIHRFIgegaDFIIITGGMSVD 243 Syntrophomonas w...
ZP_01150030 155 QVVPFlekKVGLIVTGSeVYKGRitDTFGPVLSEKMAsyGATVIELAYAPDDaQVIAEKINHAIekgaDIILVSGGMSVD 234 Desulfotomaculum...
ABA87480    165 SIKPFqpwRIGLITTGTeVFYGRipDGFGPIVKSKFEamGSEVYRQDIVPDEiQVIAAAINEQVsegaQMVVLTGGMSVD 244 Pelobacter carbi...
ABC19249    168 RVAPYrrlQVGLITTGSeVYKGRikDAFGPVVRAKIAsyGSEVALEKVVPDDaAAIHDAIEEMLaagmQMVVLTGGMSVD 247 Moorella thermoa...
ZP_00558671 165 QIRPLqskKVGVVTTGSeVYHGRiqDKFGPVLQRKVAewGSVLLGQTFADDDvEMIQERIREHIeqgaEMVLVTGGMSVD 244 Desulfitobacteri...
ZP_00676353 165 EVKPFrslRVGLVTTGNeVFHGRieDKFGPIIREKFDrlGSSVMRQILVSDNtPMTVKAIHDLIdggaEMIVATGGMSVD 244 Pelobacter propi...
CAG35000    195 GIRPFihhKVGVVTTGSeVYHGRiqDKFGPVIREKFAklGSTVMEQRFSSDDpIMTRDEILDAIaegaEMVVVTGGMSVD 274 Desulfotalea psy...
CAG36450    162 EVRPLkslKVGIITTGSeIFKGRidDAFGPILRSKFAelGCTVLGQRLVADDrAKTVEAIRDFQkegaEMIVLTGGMSVD 241 Desulfotalea psy...
EAT05203    166 RVDRMrpaKAGLVITGNeVYHGRikDAFEPVLREKLAalEAEVIEVIKTPDDaGQIAAALAQCLqagaDLLITSGGMSVD 245 delta proteobact...
Feature 1                                                      ##   #  #                        
ZP_00668460 449 PDDVTRQGLKDAGAMDMLYGAPVLPGAMTLLAR-----IGSVQVMGVPACALYFKTTSFDLLFPRLLAGVDIARRDLAKL 523 Syntrophobacter ...
EAO23581    244 PDDVTPLGIKASGAEVVFYGAPVLPGSQFMLAY-----QGHVPICGVPGGALYSKFTTLDLLLPRIFAEERINRSDIVAL 318 Syntrophomonas w...
ZP_01150030 235 PDDVTPLGIRNSGAEIIKYGAPALPGAMFLMAY-----KGDVAVLGIPACGMYFRTTVLDLVLPRLLAGDRISRRDIVKL 309 Desulfotomaculum...
ABA87480    245 PDDLTPAAIRATGARVITYGAPTYPGAMFMMAE-----LDGTPIIGLPGCTMYHKATIFELVVTRLLAGETVTRSDIVAL 319 Pelobacter carbi...
ABC19249    248 PDDVTPDGIRRSGAEVVTYGAPVLPGAMFMLAY-----RGDVPIMGLPGCVMYYRATVFDLVLPRILVGERLERHDIAGL 322 Moorella thermoa...
ZP_00558671 245 PDDLTPTAIKGLGGELITYGTPVLPGAMLLLAY-----LDDIPILGLPGCVMYSRKTVFDLVATRILAGERLTRLEIAKY 319 Desulfitobacteri...
ZP_00676353 245 PDDRTPSSIRAAGGQVVTYGSPTFPGAMFMLAY-----IGQVPVIGIPGCAMYHKATIFDLVVPRILAGETLTRSDITRL 319 Pelobacter propi...
CAG35000    275 PDDQTPTAIRATGAEVITYGSPTFPGVMFMLAV-----RDGIPILGLPGCVMYYRASIFDLVVPRLLAGVEVTREDIVAM 349 Desulfotalea psy...
CAG36450    242 PDDQTPASIRDSGADIISYGAPVLPGAMFMLAH-----LEGIPLLGLPGCVMYHAISIFDLIVPRLLAGVEIKREDIAAL 316 Desulfotalea psy...
EAT05203    246 PDDVTRTGIAAAGAREITYGTPVLPGAMFLSALlpttdGREVPVLGLPACGMFHRITVFDLILPRVLAGEKIGRETFAAL 325 delta proteobact...
Feature 1            
ZP_00668460 524 GHGSF 528 Syntrophobacter fumaroxidans MPOB
EAO23581    319 GHGGF 323 Syntrophomonas wolfei subsp. wolfei str. Goettingen
ZP_01150030 310 AHGGL 314 Desulfotomaculum reducens MI-1
ABA87480    320 GHGGI 324 Pelobacter carbinolicus DSM 2380
ABC19249    323 AAGGL 327 Moorella thermoacetica ATCC 39073
ZP_00558671 320 GHGGL 324 Desulfitobacterium hafniense DCB-2
ZP_00676353 320 GHGGL 324 Pelobacter propionicus DSM 2379
CAG35000    350 GHGGF 354 Desulfotalea psychrophila LSv54
CAG36450    317 GHGGF 321 Desulfotalea psychrophila LSv54
EAT05203    326 GHGGL 330 delta proteobacterium MLMS-1

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