Conserved Protein Domain Family
pssA
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TIGR00473: pssA 
CDP-diacylglycerol--serine O-phosphatidyltransferase
This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is involved in phospholipid biosynthesis catalyzing the reaction CDP-diacylglycerol + L-serine = CMP + L-1-phosphatidylserine. Members of this family do not bear any significant sequence similarity to the corresponding E.coli protein. [Fatty acid and phospholipid metabolism, Biosynthesis]
Links
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Statistics
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PSSM-Id: 273098
Aligned: 6 rows
Threshold Bit Score: 150.672
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q48269        14 TASSIFLGMMSIFYAssyq-------fvmACWLVVASLILDGLDGRVARLTNTT--SKFGIEFDSLADVIAFGVAPSLIA 84  Helicobacter py...
Q58609        15 TMLNIITGLLAILLN--------------SFSLIYLSIIFDSLDGYVARKTGTV--SDFGAELDSISDVVSFGVAPAYLL 78  Methanocaldococ...
P39823         9 TIGNFICGLLAIHSLlyhn-------ihsAVLFIFTGMFLDFFDGMAARKLNAV--SDMGRELDSFADLVTFGVAPSMLA 79  Bacillus subtil...
CAA29376      87 TMLNGFSGFYSIVSClrftltgkphyvqrAHFFILLGMCFDFLDGRVARLRNRS--SLMGQELDSLADLVSFGVAPAAIA 164 baker's yeast
WP_010876658  18 SMLNASSGYLSILLSidgs-------lnaACILMLLAVLFDSLDGWVARKTGRIdiHGFGKNMDSLSDVISFGVAPAILI 90  Methanothermoba...
WP_010879536  14 SVLNALFGFTAVAYLllyg------irveSYALFYLSTFSDGLDGFIAKKTE-K--SPFGKELDSLADSISFGVFPASLL 84  Archaeoglobus f...

Q48269        85 YFyvgyNFGRIGMAVSALFV-IFGAIRLARFNISTNTSdpysFIGIPIPAAAVLVVLCVLLdnkyhflegNTEKLFLSFI 163 Helicobacter py...
Q58609        79 YN----NFESNLALISAIIFcLCGALRLARFGILNVKG----FIGLPIPAGALLLVGFCQLi--------NSYLINSILA 142 Methanocaldococ...
P39823        80 YSvalyTLPFIGILCALTYS-ICGMLRLSKFNIEQSKLp--tFIGMPIPFAGMCLVILSFT---------YNPILLAIGT 147 Bacillus subtil...
CAA29376     165 FAi---gFQTTFDVMILSFFvLCGLARLARFNVTVAQLpkdsSTGKSKYFEGLPMPTTLAL------------VL-GMAY 228 baker's yeast
WP_010876658  91 YSaa-vDFRYINILVGPLIV-LCGILRLSRFNVLTGGGk--nFTGLPIPVAAVTISSFYLTg-------fYSELSAAFIM 159 Methanothermoba...
WP_010879536  85 VK-----YDANLFPFAALFL-AFSILRLARFNVLNVED----FIGVPTLVSALAVTSLVRLd--------AGYGWAAVAA 146 Archaeoglobus f...

Q48269       164 VLLGVLMVSNIRYP 177 Helicobacter pylori 26695
Q58609       143 ILIGLLMISDIKYP 156 Methanocaldococcus jannaschii DSM 2661
P39823       148 CGLSYLMVSKIKFP 161 Bacillus subtilis subsp. subtilis str. 168
CAA29376     229 CVRKGLIFDNIPFG 242 baker's yeast
WP_010876658 160 IAVSVLMISSIEYP 173 Methanothermobacter thermautotrophicus
WP_010879536 147 FLLSFLMVCDVRYP 160 Archaeoglobus fulgidus
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