Conserved Protein Domain Family
HyfC

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COG0650: HyfC 
Formate hydrogenlyase subunit HyfC [Energy production and conversion]
Statistics
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PSSM-Id: 440415
Aligned: 201 rows
Threshold Bit Score: 137.622
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010876861   4 SYSA--VTVLGTVILGLLVSLWLPGIERKfVHARIQQRIGPPVSSPgLMAALKFFYKKTVRPSSPLpRLY-NSLPIVGFI 80 
WP_011344725   5 GHLIfnFLLFPGGLFALVLGLLLMGIDRK-IVARAQRRVGPPLYQP-FIDLAKLTLKEVVVPETAHlPAF-RLAPLLGFA 81 
YP_425409      1 MENV--GLAIFNVLLVVCAAPLLDGVLRQ-VKARIHSRQGPPILQT-YFDLAKLLVKEDQRGVNQ--LLF-AWAPVVCMA 73 
YP_426509      9 LSVLfaAVVFPGGIFAITLGLALKGFDRR-VFARLQRRVGAPLLQP-FYDVLKLMTKRTLVPENANlVVF-LMVPLLGLA 85 
WP_011736634   1 MNMI--VGVLVNVILVLALAPLFQGVLRK-VTARIQSRQGPPINQP-YLDILKLLGKDDIESGEAP-VLQ-RFAAYLPLA 74 
WP_011736634   1 MNMI--VGVLVNVILVLALAPLFQGVLRK-VTARIQSRQGPPINQP-YLDILKLLGKDDIESGEAP-VLQ-RFAAYLPLA 74 
WP_012608687   1 -MEQ--LLALTAVALAILLPVLYDGIERK-TKAILQSRVGPPLHQS-LLDLGKLLSKEPVEFPSYP-LVFyTTVLSIILE 74 
YP_002248823   4 eFVI--FSSIVNILIVLILSPFFDGFTRK-VRALIQSRIGPPPLQS-YYDIIKLMGKEDLKSTIN--PLF-RLSPYLSII 76 
WP_013121783   4 ILTAfnLLIFPGFLFALGFGLFLAGVDRK-LAARIQRRVGPPLYQP-FIDLVKLMRKETVIPRAAHpTAF-QYAPLLGIA 80 
YP_011500      5 LVALfhMIVFPGGAFALTLGLLLKGLDRK-VEARLQRRVGPPIVQP-FIDLVKLTTKETLIPATANrTFF-LAAPLIGFT 81 
WP_010876861  81 SALLILLFLIppM----YTLGALASLVAIVGFLKIEEVIYVFMGSLSRSVMSmgmpfpdlargakhpdlqryfleDLSSM 156
WP_011344725  82 GMLVAVTLIP--VagvyPGLNFAGDLLVLLYLLSLPAIALIVGGSASSSPFG-----------------------AIGSS 136
YP_425409     74 SVILSALFVP--Mag-lsPLGFSGDAIVFLYVLTMAPLCMCLGGMASGSPYA-----------------------YAGAN 127
YP_426509     86 SMGVAAAMIP--IpglyDPSPAFGDLLVLFYLLSVPAVMLMLAGSASGSPFG-----------------------GIGFS 140
WP_011736634  75 VMLTIACLVP--Mgf-kaPLSGSGDVLLLILLMTLAGICTLLAGLASGSTYS-----------------------LIGIN 128
WP_011736634  75 VMLTIACLVP--Mgf-kaPLSGSGDVLLLILLMTLAGICTLLAGLASGSTYS-----------------------LIGIN 128
WP_012608687  75 FAVILVLNIA--Vl----GINTSLLMPVAIALVTVAQTANISMPLLVSNPYS-----------------------QIGGM 125
YP_002248823  77 SIGMASLLIP--IteltPPLNFWGDIFLFIYIITVVGIAIIITASASENPFA-----------------------YIGAS 131
WP_013121783  81 GLLAAIPLMP--LpgvyAGLRQPGDLLIILYLLALPALALMIGGSSSGSPFG-----------------------ALGLS 135
YP_011500     82 GMAVCAAFIP--VpgvyDGMPGMGDMLVLFYLLPLPAIALMVGGSASSSPFG-----------------------AIGFS 136
WP_010876861 157 RAFRLIAFGSFPIYIALFVPAVMSGS-------IFLKDIVAYQAvHGPVLFTLAGVVGAVVFFIGYMILLNEYPFAILKT 229
WP_011344725 137 REMVMMMAYELPLLIVLVTVALKVGLatggiatFSLSKIVQYQVeNGALLFDYTMLPALLAFLVFIPGTIGVVPFDIPEA 216
YP_425409    128 REIMTLMAVEPVVAICLITSGIRAHS-------LNLADCVNAYAaGAP---ALSMIIATIAFFLILPAELSKVPFDQAEA 197
YP_426509    141 REMAIMLAYEGPILLVIVSVALKTGAalgqpicLSLSEIVRYQQaHGAYLFDPWMWPAVLTYIAFIPANLGISPFDIPEA 220
WP_011736634 129 REMMCMITLEPLFAVAIVMGALAKGS-------FNLDEVLSGSV-YGANGMALSGFAMLVIMLLAFQAFVGRAPFDISEA 200
WP_011736634 129 REMMCMITLEPLFAVAIVMGALAKGS-------FNLDEVLSGSV-YGANGMALSGFAMLVIMLLAFQAFVGRAPFDISEA 200
WP_012608687 126 REVMLALVNEFSLVAGLALFYYYTVS-------QHPSSIMG----------WVITMPLIILVTTATYVLSGRVPFDIAEA 188
YP_002248823 132 RKMMLHLSVEPILAIALITGAINAGS-------FKIGDIVLWYYsNGP---NVSMLLSTVCVFLSLQALIGKIPFDISEA 201
WP_013121783 136 REMMMMMAYEIPLLIVLVTVALKVGLatggtatFSLSKIVEYQLnHGPLLFDYSMLPAALAFLAFIPGTVGVVPFDIPEA 215
YP_011500    137 REMTMMLAYEIPLLAVLLAVALKVGHatgvgaeLSLASVVAYQAsTGMLGLDPVMLPALLAYLLFLPGTAGVPPFDIPEA 216
WP_010876861 230 KADVIEGPYMEYAARYRAFVYITRGFLMFTLGCLFSVL-FlgVPPNIl---sWGILVNIAV-AAVFPILMAIFSAFAPVF 304
WP_011344725 217 ETEIVEGPILEYSGSWLALFKLTNALKMVVVLGLGIAL-F--FPTPLsenllLNLVWFLLKcLILLFISITIIRSSTGRV 293
YP_425409    198 ETEIMEGPLIEYSGRKLALFKWSFYAKQIVLITLFVEW-F--LPWPHmnfvpLDILATLIK-VVIVAVIIEVIAQIFPRF 273
YP_426509    221 ESEVLEGPLIEYSGVALGLLKLTSAVKSVVVIGLGIVL-F--FPNGPeg--lFGLVVFALKcLVITVCGVSVLRAAVGRM 295
WP_011736634 201 ETEIMEGAMVEYSGPKLALFQYANMAKLVVYSALFVSL-F--VPWGSglaapISFILFWVK-VFAMVLLVTTIAATHARY 276
WP_011736634 201 ETEIMEGAMVEYSGPKLALFQYANMAKLVVYSALFVSL-F--VPWGSglaapISFILFWVK-VFAMVLLVTTIAATHARY 276
WP_012608687 189 EVELASGVLIELSGRVLALYLYSIYLKRYVSSMLAAVVvFtlMPLNPl----TRFILVNVS-IPFIWILYSITSVMLGRS 263
YP_002248823 202 EQEIAEGVLIELSGPKYACVKWANMSRQVLFCLVFTQI-F--VPWPFlendlLNILIALVK-VTAIIFISTLIEALNPRL 277
WP_013121783 216 ETEILEGPLLEYSGPGLALFKIVNSLKLVVVLTLAVLL-F--YPSVLgvsplLNLLWFMAKcVVLMICSITLVRTTTARL 292
YP_011500    217 ETEIIEGPLLEYSGPALGFFHLGAALKTVVVLGLGVAM-F--FPGTVpggivPNVLWFAAKuAGLMLLSLTLVKAATGRF 293
WP_010876861 305 TFKQFYPVTAA----ASVLGVLALVTAFV 329
WP_011344725 294 RIDQAFKFYLKy---PTVLALISLILTLV 319
YP_425409    274 KIHQSIRYFYA----VVAFSVGGLVLAVM 298
YP_426509    296 RIDQAVIFYLKw---PELLGIASLALVAM 321
WP_011736634 277 RIDQAIRYFAI----MLAVSLVTLAAASY 301
WP_011736634 277 RIDQAIRYFAI----MLAVSLVTLAAASY 301
WP_012608687 264 RIDLAPGTLFKvyivLLTISITGLLVIk- 291
YP_002248823 278 RIDQALKYNLT----LALFSLTSILLALL 302
WP_013121783 293 RIDQAFKFYLTv---PAALALVSLILILF 318
YP_011500    294 RIDQAFTFYLKl---PTPLAMASLALAWL 319
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