Conserved Protein Domain Family
DUF6063

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pfam19539: DUF6063 
Family of unknown function (DUF6063)
This family of proteins is functionally uncharacterized. This family of proteins is found primarily in bacteria. Proteins in this family are typically between 237 and 249 amino acids in length. They contain a central predicted transmembrane helix.
Statistics
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PSSM-Id: 437371
Aligned: 31 rows
Threshold Bit Score: 216.338
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KUL02186          1 MKFDRENLGTALEMLHCMLAE--GSIARKDHPKEFLRYDQEAEVREAL-EFCAEKHDLLVC-----------RYNDALYL 66 
OZG52254          3 ASYSIDDISRAHEIFAILATSptHELRRTNNPDLYNDYVERDDIRELC-AQEAATWNCTIVamqarfdmpgeRDADGLCL 81 
WP_004064614      1 MAYEMEEIRTGQEIFYYLLEH--HEIREETENRLYQAYAENERIQNLV-KSQAEIACSSIE-----------RYGDVIYL 66  Eubacterium ...
OLS03307          1 MVYEIEDINQSQNIFSYLIQH--RELREDRDIGLYKAYTENENIMNLV-KMNGKASNSIVE-----------RYGNVIYL 66 
WP_055243964      1 MSYQIEEVKLSQQIFYHLLSQ--RELNEQQDKALYYAYTGNETVMNLV-KSQGEIANCVIE-----------RYGSSIYL 66  Turicibacter
CDA85620          1 MAYEMEEIQQSQEIFYLLLKE--HEIKEENEKELFRVYTQNNHVMNLV-KSQATAAESLVE-----------RYGDVIYL 66 
EEG37738          1 MAYTMEDIRKSQEIFYYLLEK--HELREEDEQALYKAYTEEEDIQNIV-KSQAETASCDIE-----------RYGNTIYL 66 
jgi:Desmer_1904   1 MITNKATLEKALELLKTLLTK--QEISREDDRDLYEDYLYNSEVEEIL-NLVAEKLELDIY-----------SYNEKIFL 66 
SNX53654          2 YNVDIENVRNAVKIFFKLIEK--GEINKIDD-REYMDMIDQSEVSDVL-NVMEEETGTIIL-----------RGSDRIYI 66 
KLU60190          3 ESYKAETVASALEIFLELVKK--GELHAEEYPQLVQTYKTDLEVQGLLtNIVEPLADVKIL-----------ESLYVLYL 69 
KUL02186         67 SPGVQNRVFGLSNAEIR-NSLGRG-FNNPEMYTVFFIIHVLITEFYHESAYDAY-VEKVAKTNLLAAVEKKIQAMG---A 140
OZG52254         82 VPDKLNTTLGYTRATLRdAVLPGSgNTMTDYYLIVFIIMTLIEMFYDGSGEDPRtRSSITMRVLQTEVERQLKIGA---E 158
WP_004064614     67 IPKEENYFLGFSKAQLKaLLCKSG-GTDKDYFLSQFVILTLLVEFYDSQGRSSKaREFLRVGDLQNSIGTYLKTGA---E 142 Eubacterium ...
OLS03307         67 IPNEDNNYLGYSKQDLKsKLCKSG-ATDKDYYLSQFVILTLLVEFYDGQGSSSKaRDYFRVGDLVNSISERLNEGV---L 142
WP_055243964     67 IPKEENEVLGFSKRELKkVLCKSS-GTDKDYYLSQFVILTLLVEFYDGQGQSAKgRDFMRVGELQNIIAERLKEGA---T 142 Turicibacter
CDA85620         67 IPKEENEYLGFTKQELKaQLCRSN-ATDKDYYLSQFVILVLLTEFYDGQGSSSKsREYMKVGELLNLVSDYLVEAG---E 142
EEG37738         67 IPQEENNFLGYSRVELKkELCKST-ATNKDYYLAQFVILTLLTEFFDGDGNSSRaREYIRSGELMNILSERLREGAayeE 145
jgi:Desmer_1904  67 TPGINNKLFGYTHEDLR-KALPYV-TRNSELFMAYFIILVVITLFYKQSGADTN-RGYVNMTEIVESTTQKLDALV---E 140
SNX53654         67 SAKTDNKVFGYNNEELR-NLLKV--SDNSELYLCYFIMLCIMCLFYAGEGYDMKcREFIEIEEIHRYADDKIKSLE---D 140
KLU60190         70 SPNLDNRFFGYTNEELR-QRLGL--TLNRELYLAYFIILSLLAMFYGEDSLSEVsRSYVTAADLERFVSERLQSLA---G 143
KUL02186        141 IQdlektSEEYQFNFKVIYDLWSSLPavefkkddpDEKKQWGVSSKVTLINETIAFLEKNQLAK--EHDDAVYLTPRCKA 218
OZG52254        159 HE-----EERDGILYTDLYNRFTALR---------SDDDDTKKTTKQGFMHYTLSFLDKQGLVNyaKDVRVFSPTAKMDA 224
WP_004064614    143 NSre-etDTERGMAFTDMYEAYEALRs--------DEKGSKAKTTKEGFLHHLLKFLEKQGLIEyvEEDEMIQTTKKLDN 213 Eubacterium ...
OLS03307        143 RNdi-evEDRDGLAFSNMLEAFEALRs--------EEKGSRAKTTKEGFIYNILKFLEKQTLIDyiEEDEMIKTTKKLDQ 213
WP_055243964    143 YYde-eqQQQLGIAYSNMLEAFEALRs--------DDRGSKQKTTKEGFLHGIFKFLQEQQLIEyiEADEMITTTKKLDQ 213 Turicibacter
CDA85620        143 NMep-eeEEKTGLAFINMLEAYSALRs--------DEHGSKARTTKEGFVYHVLQFLQKQGLIHyvERDEMIMTTKKLDR 213
EEG37738        146 EHne-eeMDTAGISFSDMCHAYEALKs--------DDKGSHAKTTKEGFLYNILLFLQKQGLIEyiERDEMIKTTKKLDS 216
jgi:Desmer_1904 141 VEnleavSSEYSFNFADIAKLWENKSfakqtrfgeISNLA--STTKMGFVHGVCNFLQGHKLIKvvDEQGLIVPTNRFKG 218
SNX53654        141 FNkteevEATLQINFGTVVQKWNSMIvyd----erKVNVQSTKNSRMAFIKKVCAFLRDQGLAIi-EEDKVLRTTEKMDR 215
KLU60190        144 AAelpewEKELEVNLLSSVELWQDMPeyd----peLKTLRRSNKNRISFILRVARFLEEDGLAHv-EQDREIYLTQKTEQ 218
KUL02186        219 IIREVYSNREVQDAITLFIDGLGHQG 244
OZG52254        225 IMERIVLTDDYFARFSRFFDVDDGEI 250
WP_004064614    214 FMDWNLLNQNHYLRVRQVLGLEKEVN 239 Eubacterium plexicaudatum
OLS03307        214 FMDYNLLNKNNYNRVLKVLGVIDNEQ 239
WP_055243964    214 LMDFNLLNQNNYTRVLHVLKEAENES 239 Turicibacter
CDA85620        214 FMDWNLLNQNHYDRVQKVLAVWKEDD 239
EEG37738        217 FMDWNLLNQNNYQRVKNILGVIENEQ 242
jgi:Desmer_1904 219 IIYNFFEDKENKSKLLTFVENLGLVN 244
SNX53654        216 MVTSYYTADDRKQEIMDFINGIKKDD 241
KLU60190        219 MVRKYYSERNRQEKLLSLLCARKEEA 244
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