2I0M


Conserved Protein Domain Family
phoU_full

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TIGR02135: phoU_full 
phosphate transport system regulatory protein PhoU
This model describes PhoU, a regulatory protein of unknown mechanism for high-affinity phosphate ABC transporter systems. The protein consists of two copies of the domain described by pfam01895. Deletion of PhoU activates constitutive expression of the phosphate ABC transporter and allows phosphate transport, but causes a growth defect and so likely has some second function. [Regulatory functions, Other, Transport and binding proteins, Anions]
Statistics
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PSSM-Id: 273990
Aligned: 26 rows
Threshold Bit Score: 163.582
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2I0M_A         3 NQFDLELHELEQSFLGLGQLVLETASKALLALAs-KDKEMAELIINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVI 81  Streptococcus p...
O28911         2 KRIEEKEKAIMDEIMEMHALAEKAVELSFRAMR--GDKSVVREISRIEQQTDVLDTDINYACTTFIALFQPVARDLRFAI 79  Archaeoglobus f...
Q9RYZ2        10 SRLDEQLERMTADFLSMQDTLAGQLRALQAAFAq-GDTSVREEVERLDRDIDAANARIEGEALHLLARQSPVAHDLKLTL 88  Deinococcus rad...
AAO04663       6 QKYEGQLDGLIKDLRRLGLRVYFNINNALVSLGe-EKKSFARQTIEKDKEINHLDHEINEKVIMLITRQQPIAKDLRMMM 84  Staphylococcus ...
O53833         3 TAYHEQLSELSERLGEMCGLAGIAMERATQALLq-ADLVLAEQVISDHEKIATLSARAEESAFVLLALQAPVAGDLRAIV 81  Mycobacterium t...
WP_000621378   4 SRFASQLNDLNKEIIFMGALCEDIIGKSLGALTn-SNDVYLDDISETYHKIEQMERDIEERCLKLLLRQQPVAKDLRRIS 82  Streptococcus a...
P47649        10 KRSEKKLLKLFFEYFKHVINAHETLNQLLCEDNleKRKELIKTIYEMEDQSNRSEFKLINESIWTISKNSPLASHLRLTI 89  Mycoplasma geni...
WP_000251235   4 eQFQCDLKTLQQKVIELGELAREALLLAMEGLHk-RDVEKALEVIDGDYRMDNLEEEINDLALMLITKQQPVASDLRRIF 82  Bacillus anthracis
WP_031786601   6 QRYQEQLDDLIKELRRLGANVYVSIENGIKSLSi-DDRGFARQTVKNDKHINQLNYDINERVIMLITKQQPIASDLRMMI 84  Staphylococcus ...
WP_010932580   4 RPVHEYIKELSEALVQLSDKVLQNFNEALYAVTh-KDVQSARKIRIVDDEIDQTEVKLEERCLAFLALQQPVARDLRTMV 82  Chlorobaculum t...
2I0M_A        82 SIMSSCSDLERMGDHMAGIAKAVLQLKenql--apdeEQLHQMGKLSLSMLADLLVAFPLHQAsKAISIAQKDEQIDQYY 159 Streptococcus p...
O28911        80 SIMRISSSYERIADIAQEISLYESKLP----------EIVFKAEKYLKKMFDAVKEGYTKTEG-LKERMTELDNAVDEIY 148 Archaeoglobus f...
Q9RYZ2        89 LILQSTPDLERAGDYAKHVARRLSALRagta---ghpSEFAQALALLLQMATTLRAASSPMNAaLAHEVRALDDQVDALY 165 Deinococcus rad...
AAO04663      85 AALKISTDFERMGDNAASIAHIRLRVKindn---yvfTRLKTMGKLAMLMLEDLNNAIRNKDLpLIKEVIERDEDIDDLY 161 Staphylococcus ...
O53833        82 SAIQMVADIDRMGALALHVAKIARRRHpqhalpeevnGYFAEMGRVAVELGNSAQEVVLSHDPeKAAQIREEDDAMDDLH 161 Mycobacterium t...
WP_000621378  83 SALKMVYDMKRIGAQAYEIAEIVSLGHiiqgs-gserDQLNSMSNNVISMLTKSIDAFIYDNEeQAHQVIEQDRTVNQEF 161 Streptococcus a...
P47649        90 TIIMSSRDLERICDYANNLTKFIEHYLhldi---kifNNLVTLHQSALNNLKKTFESLQDKEKpLTLQFENATKTIIEFE 166 Mycoplasma geni...
WP_000251235  83 ISIKTATDLERIADHAVNIAKSTIRLgekev--svslHNLDEMFAIANNMLQLALDAYEQENLtFAKQIAEMNDSVDEIY 160 Bacillus anthracis
WP_031786601  85 SSLKIASDLERIGDNASSIANIRLRTKitdd---yvlTRLKTMGKLAMLMLKDLDQAFKKKDTvLIREIIERDEDIDDLY 161 Staphylococcus ...
WP_010932580  83 TIIKINDDLERIGDLAVHIIERMPALGhev----merYQFEKMGNLSATMVRKAIEAFVTRDRlLADNVCAMDEDVDAMH 158 Chlorobaculum t...
2I0M_A       160 YALSKEIIGLmkdqe----tsipNGTQYLYIIGHLERFADYIANICERLVYLETGELV 213 Streptococcus pneumoniae TIGR4
O28911       149 VEAIEQLEES-------------CDVNAVLTVRHIERIGDLLAKIAARQIFIKEGRRV 193 Archaeoglobus fulgidus DSM 4304
Q9RYZ2       166 DRAVEQVLAGrpda------alaDTLEASHAWRAAERLGDHLVNVAQRTERLLARPAP 217 Deinococcus radiodurans R1
AAO04663     162 VNIVN--TSYlidn------dpfVAGQAHLAARHLERIGDHISNIAESVYYYLTGQHF 211 Staphylococcus epidermidis ATCC 12228
O53833       162 RHLFTVLMDRewkh------gvaAAVDVTLLSRFYERFADHAVEVARRVIFQATGAFP 213 Mycobacterium tuberculosis
WP_000621378 162 DTIKKQLVLYfsvqd----vdgeYPIDVLMIAKYLERIGDHTVNIAKWVLFSITGNld 215 Streptococcus agalactiae
P47649       167 HQYRLVLTKYyetinknevteriFLIDLVASVKHIERINDYCYNIIKSFLFIKNPEIF 224 Mycoplasma genitalium G37
WP_000251235 161 GKAIREFISSvpeqp----eaitQITQLSFVARYIERVADHITNIAENVFYLVKGKHY 214 Bacillus anthracis
WP_031786601 162 SHIIN--ATYlidn------dpfVAAQAHLAARHLERIGDHIINIAESVYFYLTGTHY 211 Staphylococcus aureus
WP_010932580 159 RMIFKKVADAmkacn----tdteQLLAVLSVSRYIERMADHATRIAREVIYLVTGEIV 212 Chlorobaculum tepidum
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