1ZBS,1ZXO


Conserved Protein Domain Family
ASKHA_NBD_PG1100-like
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cd24079: ASKHA_NBD_PG1100-like 
nucleotide-binding domain (NBD) of Porphyromonas gingivalis putative N-acetylglucosamine kinase (PG1100) and similar proteins
The family includes a group of uncharacterized proteins similar to Porphyromonas gingivalis putative N-acetylglucosamine kinase (PG1100; EC 2.7.1.59), which may convert GlcNAc to GlcNAc-6-phosphate, a component utilized in UDP-GlcNAc biosynthesis or energy metabolism.
Links
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Statistics
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PSSM-Id: 466929
Aligned: 39 rows
Threshold Bit Score: 252.132
Created: 27-Jun-2022
Updated: 27-Apr-2023
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved site include 1 residue -Click on image for an interactive view with Cn3D
Feature 1: catalytic site [active site], 1 residue position
Conserved feature residue pattern:[ED]Click to see conserved feature residue pattern help
Evidence:
  • Comment:The Asp is conserved among sugar kinases and potentially acts as a general base during catalysis.
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                        
1ZBS_A         2 ILIGDSGSTKTDWCIAk----eGKSLGRFQTsgiNPFQQDRNEIDTALRSEVLPaigqkassirAVYFYGAGCT--PAKA 75  Porphyromonas g...
SMO80537       8 MLVADSGASKTDWVLLh-----DGDKQFIQTeglNPHIVSPSQFLNTLSKELKPnlmg--ksisRIQFYGSGCGs-PQKK 79  Gracilimonas me...
RFC53779       1 MIVIESGGTKSTWVFNlpndlrGKDSFRTIGl--HPQELNSTKAETIKALVQEHqlq-----nqEVHFFGAGCEs-EEAK 72  Brumimicrobium ...
RNC79473      16 KLIVDSGATKTIWVSIi-----GGEKKRIYTegtNPALISDEEFSRIIREKLIPalpd--edydSIYFYGAGCGn-EHRA 87  Balneola sp.
WP_111064101   5 IFIFDAGGTKTDVLSLq----qGETKKYSLPg-fNPNRKEKEFLSAINELNISEn--------sQVYFYGAGIK--PAQH 69  Putridiphycobac...
TNE54424       5 ALIGDSGGSGTTWCHVd----rEGRRRQFQGpsyHPAYWSDDFWGQSSEYWKQSgie----ggpEVYLYGAGLGn-ENHC 75  Bacteroidetes b...
TNF48084       8 ILLADSGGTKTDWIAIg----gGRIIDQWTGs--SLHPVLLDHFSDSIPGEYLNy---------HLEFFGAGCHseTGKL 72  Bacteroidetes b...
WP_027419439   7 IFIFEAGSSKTSLAHNv-----DDLKITLTYpgyNPNRTNKGFLESIDQLPSAVfe------daHIYFYGSGLRh-PAKQ 74  Crocinitomix ca...
WP_090249080   5 FIIADSGGSKTHWIMSd-----EKTYKEFFSsglHPKEITPAKEEEVKALFNAYdls-----eyVLYFYGTGCLr-EENQ 73  Lishizhenia tia...
OGS76062       6 YIIADSGGSNTSWAFCn----nNTVVKLLETrsmHPKFLHSWTENDWRSLKKKLgdd----lsgRLFFYGAGCSqpAVQT 77  Candidatus Fluv...

Feature 1                             #                                                          
1ZBS_A        76 PXLNEALDSXlphcDRIEVAGDXLGAARALcgdsEGIACILGTGSNSCLFDgrEIKANVSPLGYIlGDEGSGAVLGRLFI 155 Porphyromonas g...
SMO80537      80 ENVRSFLREVfp-gVKVDVKTDLDGAGLALfskrQGIVCILGTGSSAGFFKenAIDRQMPSLGYPlGDEGSGSYIGKEIL 158 Gracilimonas me...
RFC53779      73 VKIKKFLEAFg--lDVQQVQTDLHAACVAHlgqkRGMVGIIGTGAVAALFNgeKVIQQSSGLGYMlGDEGSGFDIGKRLI 150 Brumimicrobium ...
RNC79473      88 NRVSNILRSFfl-gDEVHVKTDIEGAGLGLfgltEGILLISGTGSSAGVMRngKLVDQMPSDPFPgGDFGSGSHIGGMVL 166 Balneola sp.
WP_111064101  70 KDFLRTLMGT----SDIFVNDDLLGAARASfgdkKGAVVIMGTGANIGYYNgkTMLDQRGGYGYLiDDLGGGYELGKKIV 145 Putridiphycobac...
TNE54424      76 ASLKHHLEGIg--fRVKEMSSDVQGIAQAAlgkkRGYLAILGTGSVYQEYDqgKMLRQLGGYGHLfGDEGSAYGFGRILV 153 Bacteroidetes b...
TNF48084      73 ALISKLKSLGf---TSINVNSDLYEAGLSLfgkdKGCGFISGTGSVAFKYDgeSITDIYGGLGHIlGDEGSGFYFGKLLL 149 Bacteroidetes b...
WP_027419439  75 LEIKTYFKERf--qTNIEVFDDVLGAARALllkkEGVIAIMGTGACVAYYDgrNIIESTGGHGYLiDDIGGGYELGKLIT 152 Crocinitomix ca...
WP_090249080  74 TPVKELLTTLg--fNETHIYGDVVGSCRAAladaPGDVLILGTGSVGLKYDgeKITETFGGLGYPhGDEGSGARMGKMLI 151 Lishizhenia tia...
OGS76062      78 TMVERLVRFGf---ESPVVYPDTLGACRATcgrnSGVVGILGTGSVMLEYDghHITGRVGGYGSLvGDEGSGFYFARLVV 154 Candidatus Fluv...

Feature 1                                                                                        
1ZBS_A       156 GSLLKgq--xPEGLCEAFLQEYGltSADIIESVYRKpf--pnRFLAGFSPFIAQhl-dIPAVYSLVQNSFDDFLVRNVLR 230 Porphyromonas g...
SMO80537     159 VAYLEgr--lHKDLRVYLEEQLKmdLDEIFAQVQTPem--akLFVSRLCKLMSKks-yHPEMQNILDHGFCDFLNKVKEH 233 Gracilimonas me...
RFC53779     151 VQHLNhq--lPSEITKEIDTYFE--YRSIVHRVQESdg---rMKIAGLTKIVRKys-dDPVIFKILKEAFSDFCKTALLP 222 Brumimicrobium ...
RNC79473     167 QAYLKgk--aPSTFVEIIQTSGGgnKDELLSKLKDQks---aKRIASHTMFIVKelseHDFLHNIAERSIRLFFEELDGY 241 Balneola sp.
WP_111064101 146 SAWLSgd--lNEQTNQVIQDYICtpKENFITTFYQNid---lGLLAGLCKIVLPeiekDPNLKTITLNYFDVFVKTHLIP 220 Putridiphycobac...
TNE54424     154 RKYLDgl--lPGSLYKWMEEKYPs-RESLLAALSHSsmkyelGQLAVQSQNCQE----KEFIEEIHLENLKAFQESCLKH 226 Bacteroidetes b...
TNF48084     150 VEYLNnr--lPKEIEDFLSLQLGs-RAEILPNVYGSec---kAYVSKLSELTQSi--kHDVITNLHKKNIELFVESFVGY 221 Bacteroidetes b...
WP_027419439 153 SYWLNgq--mNAAQDKSMADHFGvsRTDFTSYYYLEkd---lNSVAQVVRLINDf--kTNDIEQLLLDYFDIFFKRHVNS 225 Crocinitomix ca...
WP_090249080 152 EGYQHkt--lSPELIAKLEAYKTniSFPLNTPVEEIn----rKEIATLSKFLFEhk-aEEEVQSILRTSFQEMYTTTVEP 224 Lishizhenia tia...
OGS76062     155 RDYLTasssmSPFVRNQLREVIGs-SAEVLARLAGP------DAQTWLNELGARf--kGIDLSYYHYCNLSEWLDTSLPS 225 Candidatus Fluv...

Feature 1                                                          
1ZBS_A       231 ynr--pdlPLHFIGSVAFHYREVLssvikkrGLTLGSVLQsPXEGLIQYH 278 Porphyromonas gingivalis W83
SMO80537     234 fpeesaahQLGFVGSIASVYEAELracakqmGLEISSVIRtPIEHIAFHF 283 Gracilimonas mengyeensis
RFC53779     223 iqe---nhPIHFIGSVAYYFQEELkstlssmGYEMGGVEKeAVEGVFEFL 269 Brumimicrobium aurantiacum
RNC79473     242 fsedlkifPIKVNGSTAFHFSNIFreifgeaGIQIDMIQKnPIDELVHFH 291 Balneola sp.
WP_111064101 221 fsnkhhfnSISCVGSIAFYYKKYItiafsknGIRIDSILLkPITELFKFH 270 Putridiphycobacter roseus
TNE54424     227 hse--dlkTGYFVGSYAVAQSGKIkqlleevNLEVEEFVAePIELIVDFL 274 Bacteroidetes bacterium
TNF48084     222 ntg---atAINACGSYAYHYHEHFkvafekrGVSIGRIIKrPLEKIAENM 268 Bacteroidetes bacterium
WP_027419439 226 ilekyntnEISFVGSISSNFNAEIvqvaqsnGIKVTSINQfPVNALLNFH 275 Crocinitomix catalasitica
WP_090249080 225 mh----tnSISVTGSIAFYFKDELkdflfskQIVVNRIVKyPALNLYSLH 270 Lishizhenia tianjinensis
OGS76062     226 lkk--ypkVISVIGSYGFSQREILeqlvderFMTLGTLCKsPMEGLVNFH 273 Candidatus Fluviicola riflensis

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